1

Appendix 1: Scientific advisory and organizing committee, and faculty

Scientific advisory and organizing committee:

Rome Foundation: Ami Sperber, Doug Drossman, Lin Chang, Max Schmulson

WGO – Eamonn Quigley, Richard Hunt, Kok-Ann Gwee, Carolina Olano

IFFGD – Nancy Norton

Co-Directors

Ami Sperber MD, MSPH,Tel-Aviv Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Eamonn Quigley MD, University College Cork, Cork, Ireland

Faculty

Paul Brodwin PhD, University of Wisconsin-Milwaukee, Milwaukee WI, USA

Lin Chang MD, UCLA, Los Angeles CA, USA

Sheila Crowe MD, University of Virginia, Charlottesville, VA, USA

Douglas Drossman MD, University of North Carolina at Chapel Hill, NC, USA

Dan Dumitrascu, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania

Shin Fukudo MD, PhD, Tohoku University, Sendai, Miyagi, Japan

Mary-Joan Gerson PhD, New York University, New York, NY, USA

Uday Ghoshal MD, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow India

Byron Good PhD, Harvard University, Boston, MA, USA

Kok-Ann Gwee MD, PhD, National University of Singapore, Singapore

Albena Halpert MD, Boston Medical Center, Boston MA, USA

Pali Hungin MD, Durham University, Durham, UK

Richard Hunt MD, McMaster University, Hamilton, Ontario, Canada

Nusrat Husain MD, University of Manchester, Manchester, UK

Mei Yun Ke MD, Peking Union Medical College Hospital, Beijing, China

Carolina Olano MD, Universidad de la República, Montevideo, Uruguay

Donald Patrick PhD, University of Washington, Seattle, WA, USA

Ben Saypol. PhD, Loyola University, New Orleans, LA, USA

Max Schmulson MD, Universidad Nacional Autónoma de México-UNAM, Mexico City, Mexico

Brennan Spiegel MD, MSHS, UCLA, Los Angeles CA, USA

Robin Spiller MD, University of Nottingham, Nottingham, UK

Jon Streltzer MD, MSW, University of Hawaii at Manoa, Honolulu, HI, USA

Nick Talley MD, PhD, University of Newcastle, New South Wales, Australia

W. Grant Thompson MD, University of Ottawa, Ottawa, Ontario, Canada

Masao Kobayakawa MD, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan

Marc Zuckerman MD, Texas Tech University, El Paso, TX, USA

Appendix 2. Symposium program

Day 1-April 6, 2011

Time / Topic / Speaker/s
8-8:20 / Greetings and introduction
8:00-8:10 / The RF and theWGO: a global collaboration / Drossman, Quigley
8:10-8:20 / Introduction and goals of the symposium / Sperber
8:20-10:15 / Epidemiology and socio-cultural issues / Chair: Quigley, Olano
8:20-8:40 / How symptoms mediate culture and biology / Good
8:40-9:20 / Interpretation and reporting of GI symptoms, differential diagnosis and diagnostic work-up around the world / Gwee, Ghoshal, Dumitrascu, Schmulson
9:20-10:15 / Discussion and Q&A
10:15-10:45 / Break
10:45-12:00 / Culture, health and FGIDs / Chair: Sperber, Schmulson
10:45-11:05 / Culture and health care / Streltzer
11:05-11:30 / Explanatory models of illness: basic framework & applications for care of people with FGIDs / Brodwin
11:30-12:00 / Discussion and Q&A
12:00-13:30 / Mechanisms and pathophysiology / Chair:Spiller, Fukudo
12:00-12:15 / A global perspective on the effect of genetics and ethnicity on pathophysiology and management / Talley
12:15-12:30 / GI microbiology – pathogens, exposure patterns and immune responses / Spiller
12:30-12:45 / Geographical and cultural food-related symptoms, food avoidance and elimination / Crowe
12:45-13:00 / Worldwide differences in psychopathology and the interpretation and effects of stress / Good
13:00-13:30 / Discussion and Q&A
13:30-14:30 / Lunch
14:30-16:15 / Patient care in different geographical areas and cultural settings / Chair: Thompson, Gwee
14:30-14:45 / Practicing in a multicultural milieu – physician competence / Husain
14:45-15:00 / Practicing in a multicultural milieu– listening for stories / Good
15:00-15:15 / Folk remedies, self-medicating, and CAM around the world / Mei YunKe
15:15-15:30 / Impact of local regulations and health care organization on management options / Quigley
15:30-15:45 / Cultural beliefs and health care:searching for balance / Brodwin
15:45-16:15 / Discussion and Q&A
16:15-17:30 / Clinical competence workshop / Chair: Drossman
Workshop 1 /
  1. Working in a multiethnic clinic
  2. Role play with professional actors - clinical encounters with cross-cultural issues
/ Saypol, Halpert, Chang
Workshop 2 / Research competence workshop / Chair: Quigley
  1. Cross-cultural, multinational research (5 min)
  2. Examples of cross-cultural studies (12 m each)
  3. Translation and validation of instruments for cross-cultural studies (10 min)
  4. Expression of gastrointestinal symptoms across countries: similarities and differences (12 min)
  5. Discussion (12 min)
/ Sperber
Zuckerman, Gerson, Hungin
Sperber
Patrick
17:30-18:30 / Reception for all conference participants
19:00 / Faculty dinner

Day 2-April 7, 2011

Time / Topic / Speaker
8:00-10:00 / Conducting multinational drug trials / Chair: Spiegel, Talley
8:00-8:30 / Unique problems in multi-national studies: ethical issues, inclusion criteria and recruitment problems / Spiegel
8:30:8:45
8:45-9:00
9:00-9:15 / Unique problems in multi-national studies: regional perspectives on endpoints and outcomes / Japan – Kobayakawa
EMEA – Schabel
FDA – Trentacosti
9:15-10:00 / Discussion and Q&A / Spiegel,Talley, Kobayakawa, Schabel, Trentacosti, Gwee, Hungin, Schmulson, Spiller
10:00-10:30 / Break
10:30-11:00 / Summary of workshops and meeting / Chair: Drossman
10:30-10:45 / Summary of clinical practice workshop / Drossman
10:45-11:00 / Summary of research practice workshop / Sperber
11:00-12:00 / General discussion: How should we proceed? / Quigley, Sperber, Drossman
12:00 / Adjourn