ANNEX A:SAMPLING TECHNIQUES

1.Non Probability Sampling Methods

There are two common types of non probability sampling, namely convenience or purposive sampling and quota sampling.

a.Convenience Sampling

Convenience sampling is that in which the study units that happen to be available at the time of data collection are selected for purposes of convenience. Most clinic based studies use this method. It is the common method for selecting participants to a focus group discussion.

b.Quota Sampling

Quota sampling is used when it is considered that convenience sampling would not provide a desired balance of study units. For example when assessing patient understanding of how to take drugs, a quota sample could be used to ensure that both males and females are covered in the study.

Non probability sampling methods are less representative than probability sampling methods and thus inappropriate if the objective of a study is to generalize findings. They are often used in qualitative methods because of their flexibility in adapting to local situations and settings.

2.Probability Sampling Methods

Probability sampling techniques are those that involve the random selection of study units by chance. For this to be possible, a sampling frame must exist. There are a number of probability sampling techniques and any of them could be used in a study depending upon the study problem and the purpose of the study. These comprise;

Simple Random Sampling (SRS)

a.Simple Random Sampling (SRS)

This is the simplest form of probability sampling. It involves:

! making a numbered list of all units in the study;

! deciding the size of your sample;

! choosing the number you require.

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For example, suppose we are faced with a problem of selecting 60 households in a community of 360 households to learn more about their attitudes towards the use of antibiotics in cough. We could proceed by first giving each household a number. These numbers are then written on small pieces of paper and placed in a box. Numbers are then picked from the box up to the required total, making sure that that the box is well shaken each time to ensure the principle of equal and random selection.

b.Systematic Sampling

The principle involved in using this method is similar to the SRS, but with an added condition that the selection of units is based on regular intervals starting from a determined point. To use the example above, we can obtain our interval by dividing 360 by 60 which gives 6. Once the sample interval has been determined, the first unit is then drawn between 1 and 6.

Afterwards, every sixth case must be drawn until the total sample of 60 has been drawn.

The technique is particularly useful where large numbers are involved such as the sampling of prescription records. For instance, if we need 30 prescriptions from a register in a health facility which contains 50 pages of 25 lines per page, the sampling interval must be calculated by dividing the product of 50 and 25 by 30 to obtain 41.7. Based on this figure, every 42nd prescription would be selected for the study.

c.Stratified Sampling

This is an alternative method to systematic sampling and preferable where the sampling frame contains distinct populations. For example, assuming our antibiotics study covers an entire district, it would be necessary to ensure that both rural and urban facilities are adequately covered. This would not be possible using the SRS or systematic sampling techniques.

Alternatively, using a procedure that groups study units who are similar in certain characteristics into strata ensures that all relevant groups are appropriately covered. In drug use studies stratified sampling could be used to sort facilities into various levels of care, i.e., community clinics from health centers and both from district hospitals. When the method is used, the final stage of selecting the units is also based on the principle of equal selection by chance.

d.Cluster Sampling

Assuming our district is a large one with a landscape that makes travelling around facilities difficult, then cluster sampling offers a better alternative. This involves selecting clusters or groups of study participants or units rather than on individual basis. Clusters may be villages or families or a specified group of patients or providers.

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For example, if we want to select two facilities for study in a geographically difficult area, then we could select a cluster of two facilities by randomly selecting a single facility and then selecting another one close to it. The method saves time in data collection.

e.Multi-Stage Sampling

This is a combination of all the methods described above and is very useful if the purpose of the structured observation method is to generalize study results from diverse populations. As the name implies, it involves sampling in two or more stages as follows:

1.Forming clusters and selecting a random sample of these.

2.Making a separate list of all study units within each of the selected clusters.

3.Selecting study units separately from each cluster in the sample.

4.Interviewing selected study units.

For example, if we intend to select 12 health facilities in a district with 36 facilities, we can first group them into the various clusters or levels of health care such as community clinics, health centers, and hospitals. We can then randomly select our 12 facilities from the 3 groups. This is two-stage sampling. If we want to select 30 prescriptions from each facility, we can continue from this stage with the process described in selecting every 42nd prescription under systematic sampling. This is three-stage sampling.

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ANNEX B:BIBLIOGRAPHY

GENERAL

Laing RO., "Rational Drug Use: An Unsolved Problem" Tropical Doctor,Vol ? 1990.

Hudelson PM., Qualitative Research for Health Programmes. 1994, WHO/MNH/PSF/94, Geneva.

Heggenhougen K, Draper A. Medical Anthropology and Primary Health Care. 1990, London School of Tropical Medicine and Hygiene, London.

Varkevisser CM, Pathmanathan I, Brownlee A, (1993) Designing and Conducting Health Systems Research Projects. Health Systems Research Training Series, Vol. 2 Part 1, Ottawa

Lutz, W. (1986). Planning and Organizing a Health Survey. International Epidemiological Association, Switzerland.

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CHAPTER 3:IN-DEPTH INTERVIEW

1.PATH. Developing health and family print materials for low-literate audiences: a guide. PATH, 1988; pp. 17-18.

2.UNICEF. Baseline data for FGN/UNICEF 1991/95 country program: Manual for rapid assessment procedures. UNICEF, 1991; pp. 1-5.

3.World Health Organization. How to investigate drug use in health facilities: selected drug use indicators. Geneva: World Health Organization, 1993 (WHO/DAP/93.1).

FURTHER READINGS

4.Scrimshaw SCM, Hurtado Elena, (1987). Rapid Assessment Procedures for Nutrition and Primary Health Care: Anthropological Approaches to Improving Programme Effectiveness, pp. 11-12.

5.Kashyap P, Young RH. (19??). Rapid Assessment of Community Nutrition Problems: a Case Study of Parbhani, India, pp. 3-5.

6.Forcese DP, Richer S. (1973). Social Research Methods. Englewood Cliffs NJ: Prentice-Hall, Inc., pp. 168-177.

7.Lockerbie L., Lutz W., (1986) Questionnaire Design, International Epidemiological Association, Switzerland.

8.Hepburn W., Lutz W., (1986) Interviewing and Recording, International Epidemiological Association, Switzerland.

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CHAPTER 4:FOCUS GROUP DISCUSSION

Varkevisser CM, Pathmanathan I, Brownlee A, (1993) Designing and Conducting Health Systems Research Projects. Health Systems Research Training Series, Vol. 2 Part 1, Ottawa

Scrimshaw SCM, Hurtado E. Rapid Assessment Procedures for Nutrition and Primary Health Care. 1987, University of California Press, Los Angeles

Dawson S, Manderson L, Tallo VL., The Focus Group Manual. 1992, World Health Organization, Geneva.

Bernard HR. Methods in Cultural Anthropology. 1988, Sage Publications, California.

Stewart DL, Shamdasani PN. Focus Groups, Theory and Practice. 1990, Sage Publications, California.

FolchLyon E, Trost JF. "Conducting Focus Group Sessions." Studies in Family Planning Dec. 1981; 12(12):443448.

Heggenhougen K, Draper A. Medical Anthropology and Primary Health Care. 1990, London School of Tropical Medicine and Hygiene, London.

Peelers RF. Methodology of Health Behavior Research. 1989, Esoc. Publication Nr. 19;

Program for Appropriate Technology in Health (PATH). Focus Group Discussion Use in the Preparation of Materials. [DATE??] Washington DC.

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CHAPTER FIVE:STRUCTURED OBSERVATION

OTHER READINGS

Grady KE, Wallston S., Reasearch in Health Care Settings. Newbury Park: Sage, 1991.

Oladepo O, Oyejide CO, Oke EA., "Training Field Workers to observe Hygiene-related behaviour." World Forum 12, 1991.

Nietzel MT, Bernstien DA, Introduction to Clinical Psychology. Englewood Cliffs, NJ: Prentice Hall, 1987.

Varkevisser CM, Pathmanathan I., Brownlee A., Designing and Conducting Health Systems Reasearch Projects, Vol. 2, Part 1. Ottawa: IDRC, 1993.

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CHAPTER SIX:STRUCTURED QUESTIONNAIRE

1.World Health Organization (1993). How to Investigate Drug Use in Health Facilities: Selected Drug Use Indicators. Geneva: (WHO/DAP/93.1).

Additional Readings

Abrahamson, J.H. (1979). Survey Methods in Community Medicine. Churchill Livingstone, Edinburgh, 114-115.

Selltiz, C, Wrightsman, L.S., Cook, S.W. (1976). Research Methods in Social Relations. Holt, Rinehart and Winston; New York, 542-557.

Denzin, N.K. (1970). The Research Act in Sociology. Aldine Publishing Company, Chicago.

Varkevisser, C.M., Pathmanathan, I., Brownlee, A. (1993). Designing and Conducting Health Systems Research Projects, Vol. 2, Part 1. International Development Research Centre, Ottawa.

Hepbun, W., Lutz, W. (1986). Interviewing and Recording. International Epidemiological Association, Switzerland.

Lockerbie, l. Lutz, W. (1986). Questionnaire Design. International Epidemiological Association, Switzerland.

Lutz, W. (1986). Planning and Organizing a Health Survey. International Epidemiological Association, Switzerland.

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ANNEX C1:Example of Interview Guide for Mothers at OPD Assessing Use of Antibiotics in Treatment of Respiratory Infections

Introduction: As in the interview guide for the prescribers.

General Background: Mother and community.

Interview Start: Could you please tell me what treatments are available in the community for treatment of colds in young children. What about your educational background, age, number of children alive, marital status etc. ... Just to tell me a little bit about your status.

Community Perception of Causes of Respiratory Infection: As a care giver to young children and a member of this commuknity, what do people here believe causes respiratory infections in young children? What about your own belief? How do you know a child has respiratory infection? What specific signs are there for each type of respiratory infection?

Treatment Of Respiratory Infections In Children:

What treatments are available in this community for treatment of colds in young children?

Probe: The types of treatment mothers prefer most? What traditional remedies are available in community? Ask about popular home remedies used by people. At what stage in the course of the ailment do mothers or care givers take their children to the clinic/hospital or contact modern orthodox health facility?

Probe into:

*Types of treatment given by clinic/doctor.

*Kinds of drugs/tables or injections given - provide names or descriptions.

*Medications given for treatment of mild, severe colds in children.

*Perception of mothers on effectiveness of the drugs?

*Mothers' expectations from different courses of treatment - what about antibiotics (use local concepts and terminologies).

*Medications mothers prefer for (a) mild (b) severe colds.

Cost of Treatment (Medications) of Colds in Children:

*How much do you have to pay for a typical treatment of episode of respiratory infection of your young child? What about payment for (a) antibiotics (b) other drugs.

*What about costs of treatment of severe colds for your child? What differences occur in prices or payment in a government and private clinic?

*Are mothers able to afford the costs?

*What difficulties are experienced by mothers over payment for medications?

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Dispensing Process: From your experience, do mothers get prescribed drugs at the clinic pharmacy often or most of the time?

*What sources do mothers rely on most for drug supply when they visit government clinics?

*What other sources?

*Do mothers get specific instructions on how their children should use prescreibed drugs? What instructions?

Suggestions: Is there any point you still want to elaborate upon on how children are treated for episodes of colds? What suggestions do you have for improvement of health care for children in the community, at clinic? Any other comments?

Close: Expression of appreciation.

Note: The draft interview guides can be discussed with colleagues or preferably proof-read by them before a training session with interviewers to ensure its test of suitability.

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ANNEX C2:

The following are draft outlines of protocols for observation of the prescribing and dispensing processes. Most will come from direct observation. Some will need to be filled in at the end of the visit or end of the day from the patient record.

CLINICAL PROCESS OBSERVATION FORM

IDENTIFYING INFORMATION

Sequence #:

Health Facility: ______Date:

Patient Age: < 5 5-12 over 12 Sex:

Provider Type: Doctor CMO Nurse

DIAGNOSTIC COMMUNICATIONPrescriberPatientNot

AsksVolunteersDiscussed

Length of current problem episode?

Presence of:fever?

headache?

malaise?

muscle weakness?

loss of appetite?

chills?

vomiting?

bitter taste?

Patient mentions malaria?

Previous treatment for this episode?

Any previous drugs taken this episode?

Last time treated for malaria?

Name of drug used to treat last time?

Patient finished last course of treatment?

Comments

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EXAMINATIONDoes Not

YesNoApply

Temperature measured?

Patient touched for fever?

Pulse felt?

Conjunctivitis/Sclera of eye examined?

Tongue examined?

Listens to chest?

Palpates abdomen?

Comments

TREATMENTDoes Not

YesNo Apply

Injection given

(If injection) Sterile technique followed

Advised lab test?

Advised exam at different facility?

Advised return visit if not better?

Comments

COMMUNICATIONDoes Not

YesNoApply

Patient asks for:injection?

chloroquine?

halofantrine?

Provider explains how to use drugs?

Provider offers advice on malaria prevention?

Provider offers nutrition advice?

Comments

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PROVIDER-PATIENT INTERACTIONDoes Not

YesNoApply

Patient greets prescriber?

Prescriber greets patient?

Friendly conversation?

Provider gives reassurance to patient?

Patient encouraged to describe problem freely?

Doctor listens to responses?

Provider ends encounter abruptly?

Patient appears to want more information?

WRAPUP

Observer: ______

Length of consultation (mins):

Notes:

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DISPENSING OBSERVATION FORM

IDENTIFYING INFORMATION

Sequence #:

Health Facility: Date:

Patient Age: < 5 5-12 over 12 Sex:

COMMUNICATIONDispenserPatientNot

InitiatedInitiatedDiscussed

Description of drugs dispensed?

Instructions on how to take drugs?

Cautions, side effects mentioned?

Information about prevention/care?

DISPENSING ACTIONSDoes Not

YesNoApply

(If injection) Sterile technique followed

Drugs labeled with (Check one or more):

Patient name Drug name How to take No label

Type of package in which drugs dispensed (Check one or more):

Plastic/glass bottle Plastic bag Envelope

Folded Paper None

WRAPUP

Observer: ______

Length of dispensing process (seconds):

Notes:

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ANNEX C.3:EXAMPLE OF QUESTIONNAIRE

Study Title:

AN ASSESSMENT OF THE OUTPATIENT CARE PROCESS IN SELECTED HEALTH CENTERS

Specific Objectives:

1.To estimate the proportion of outpatients adequately during consultation.

2.To assess the dispensing process at the health centers.

3.To identify the main reasons for patients' satisfaction/dissatisfaction with the treatment received.

PATIENT INTERCEPT INTERVIEW

(Introduction)

1.What is the main complaint/ailment for which you have come here to seek treatment?

2.Is this your first visit for this ailment?

(1) Yes (Skip to Q.4)(2) No

3.How long ago was your last visit?

.....days.....months before

4.Did you consult any practitioner for this episode of illness before coming here?

(1) Yes(2) No (Skip to Q.6)

5.Whom did you consult? (Probe to specify type of practitioner)

6.Has the doctor of this facility told you the name of the disease?

(1) Yes(2) No (Skip to Q.8)

7.What is the disease/diagnosis? (Skip to Q.9)

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8.Did you ask the doctor the name of your disease?

(1) Yes(2) No

9.Did the doctor physically examine you?

(1) Yes(2) No

10.Do you feel that physical examination was necessary to diagnose your disease?

(1) Yes(2) No

11.Did you have the chance to fully describe your illness to the doctor?

(1) Yes(2) No

12.Did the doctor advise any laboratory test?

(1) Yes(2) No

13.How many drugs did you receive from this facility?

...... (Check the patient's prescription)

14.Did the doctor here give you a prescription for a drug that you must buy outside of this facility?

(1) Yes: How many? ...... (Number)

(2) No (Skip to Q.15)

15.Did the pharmacist explain to you how to take the drug?

(1) Yes(2) No

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16.Would you please tell me how to take the drugs?

(Look at the prescription and compare patient's answer)

1st Drug(1) Correctly stated(2) Not correct

2nd Drug(1) Correctly stated(2) Not correct

3rd Drug(1) Correctly stated(2) Not correct

17.Would you please rate your satisfaction or dissatisfaction with the treatment you have received?

(1) Highly satisfied(Skip to Q.19)

(2) Satisfied(Skip to Q.19)

(3) Okay(Skip to Q.19)

(4) Dissatisfied

(5) Highly dissatisfied

18.What are the main reasons for your dissatisfaction?

(Record maximum three reasons)

(1)

(2)

(3)

19.Will you visit this health facility again in case of sickness?

(1) Yes(2) No

20.Do you have any specific complaint about any aspect of the health facility?

(1) Yes(2) No (Skip to Q.22)

21.What is your complaint?

22.Do you have suggestions on how to improve patient care?

(1) Yes(2) No (Skip to Q.24)

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23.What are these suggestions?

(Record maximum three suggestions)

(1)

(2)

(3)

24.Do you have any other comments on the facility?

(1) Yes(No) (Stop interview; thank patient)

25.What are your comments?

(1)

(2)

(3)

Stop interview and thank patient.

Name of Interviewer:

Signature:

Date:

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