第四届DNA损伤应答与人类疾病研讨会

会议日程安排

Oct. 18th (Friday), 2013

Registration

All day, lobby at the Jinlongtan Hotel

Oct. 19th (Saturday), 2013

Opening ceremony

8:00-8:50

DNA damage response I, chairs: Tomas Lindahl& Guoliang Xu (9:00-11:45)

9:00-9:25

Yossi Shiloh, Sackler School of Medicine, Tel Aviv University, Israel

ATM: a busy intersection

9:25-9:50

Peter McKinnon, St. Jude Children’s Research Hospital, Memphis, TN, USA

DNA damage signaling in the nervous system

9:50-10:15

Xingzhi Xu, Beijing Key Laboratory of DNA Damage Response, CNU, Beijing, China

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response

Tea break: 10:15-10:30

10:30-10:55

Qimin Zhan, Chinese Academy of Medical Sciences & Cancer Hospital, Beijing

TBA

10:55-11:20

Wei Yang, NIH, USA

Mechanisms for DNA lesion recognition, repair and bypass

11:20-11:45

Wei Xiao, Beijing Key Laboratory of DNA Damage Response, Capital Normal University, Beijing

DNA-damage Tolerance Mediated by PCNA Mono-ubiquitination Is Dependent on Rev1

11:45-1:30

Lunch and poster session

DNA replication checkpoint, chair: TBA (1:30-5:10)

1:30-1:55

Guoliang Xu

1:55-2:20

Zhao-Qi Wang, Leibniz Institute for Age Research/Fritz Lippman Institute, Jena

TBA

2:20-2:45

Zhixiong Xiao, Sichuan University, Sichuan

TBA

2:45-3:10

Xialu Li, Capital Normal University, Beijing, China

TBA

3:10-3:35

Lee Zou

Sensing and Signaling DNA Damage through the ATR Checkpoint

Tea break: 3:35-3:55

3:55-4:20

Daochun Kong, Peking University, Beijing

TBA

4:20-4:45

Han You, Xiamen University, Fujian, China

TBA

4:45-5:10

Yuejin Hua, Zhejiang University, Hangzhou, Zhejiang

A Novel Stress Response Mechanism in Deinococcus radiodurans

Oct. 20th (Sunday), 2013

DNA Damage response II, chair: Yossi Shiloh (8:30-11:50)

8:30-8:55

Junjie Chen, PhD, Professor, University of Texas MD Anderson Cancer Center, USA

Protein-protein interaction network involved in DNA damage repair and tumorigenesis

8:55-9:20

Huadong Pei, Beijing Proteome Research Center, Beijing, China

TBA

9:20-9:55

Axel Behrens, CR-UK London Research Institute, London, UK

A novel arm of ATM signalling pathway defined by the ATMIN cofactor

Tea break: 9:55-10:15

10:15-10:40

David Chen, University of Texas Southwestern Medical Center, USA

DNA-PK Complex and the Pathway Choice of DSB Repair

10:40-11:05

Steve Smerdon, MRC National Institute for Medical Research, London, UK

A molecular view of mediator function in the DNA-damage response

11:05-11:30

Zhiyong Mao, Tongji University, Shanghai, China

TBA

11:30-1:00

Lunch and poster session

Post-translational modifications in DDR, chair: TBA (1:00-4:45)

1:00-1:25

Daniel Durocher, Samuel Lunenfeld Research Institute, Canada

How cells write and read the DNA damage-induced chromatin code

1:25-1:50

Xiaobo Qiu, Beijing Normal University, Beijing, China

Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis

1:50-2:15

Guo-Min Li, University of Kentucky, USA

TBA

2:15-2:40

Yungui Yang, Beijing Institute of Genomics, CAS, Beijing

Ago2 is required for Rad51 recruitment and repair of DNA double-strand breaks by homologous recombination

2:45-3:05

Jun Huang, Zhejiang University, Hangzhou, Zhejiang

Chromatin remodeling and Homologous Recombination Repair

Tea break: 3:05-3:30

3:30-3:55

Titia K. Sixma, Netherlands Cancer Institute, Netherlands

Specificity in H2A ubiquitination

3:55-4:20

Michael Huen, University of Hong Kong, Hong Kong

Regulators of Ubiquitin Signaling at DNA Double-Strand Breaks

4:20-4:45

Fangwei Wang, Zhejiang University, Zhejiang, China

Coordinated actions of protein kinases to orchestrate chromosome segregation in mitosis

4:45-5:00

Wei Xiao, Zhao-Qi Wang, and Xingzhi Xu

Poster Awards and closing remarks