Warwick Medical School
2ndInternational Symposium on
Advances in Human Metabolism Research
PROGRAMME
Thursday 16MAY 2013
Society for Endocrinology Seminar
‘Metabolism, Mitochondria and Fatty Acids’
08.30 REGISTRATION, COFFEE, EXHIBITION
ChairProfessor Jonathan Arch
Clore Laboratories, University of Buckingham, UK
09.15Welcome
Professor Sudhesh Kumar, Warwick Medical School, UK
09.30Plenary Session: Uncoupling proteins
Professor David Nicholls, Buck Institute for Research on Aging, USA
10.00Fatty acid-induced defects in the bioenergetics of INS-1 insulinoma and skeletal muscle cells
Dr Charles Affourtit, Plymouth University, UK
10.30Studying mitochondrial morphology and dynamics
Professor OrianShirihai, Boston University School of Medicine, USA
11.00 COFFEE, POSTER SESSION, EXHIBITION
ChairDr John Clapham
Warwick Medical School, UK
11.45Elucidation of the routes of triglyceride synthesis: implications for metabolic homeostasis
Professor Victor Zammit, Warwick Medical School, UK
12.10Regulation of lipogenesis in developing adipocytes
Dr Justin Rochford, Rowett Institute of Nutrition and Health,
University of Aberdeen, UK
12.40CIDEA-dependent lipid droplet enlargement: how cells get fat
Dr Mark Christian, Warwick Medical School, UK
13.10 LUNCH, POSTER SESSION, EXHIBITION
ChairProfessor Charles Hutchinson
Warwick Medical School & University Hospitals Coventry and Warwickshire, UK
14.40Quantifying brown adipose tissue in human adults
Dr Tom Barber, Warwick Medical School & University Hospitals Coventry
and Warwickshire, UK
15.00IDEAL-MRI for the imaging of brown adipose tissue in human adults
Professor Charles Hutchinson, Warwick Medical School & University Hospitals Coventry and Warwickshire, UK
15.20 MRI of pericardial fat and heart function: (i) Newly refined ventricle-
specific analyses and (ii) imaging pre-and post-bariatric subjects
Professor James A Hamilton, Boston University School of Medicine, USA
15.50 Closing remarks
Professor Victor Zammit, Warwick Medical School, UK
16.00 - 18.00 CHEESE & WINE, POSTER PRIZES, EXHIBITION
19.30 Official Dinner(for registered delegates only)
Friday 17 MAY 2013
Training Workshop: ‘Energetics: from eukaryotes to man’
(for workshop registered delegates only)
8.00REGISTRATION, COFFEE
8.15Welcome
Professor Victor Zammit, Warwick Medical School, UK
8.30Mitochondrial diagnosis
Professor OrianShirihai, Boston University School of Medicine, USA
9.15Cellular Bionergetics
Professor David Nicholls, Buck Institute for Research on Aging, USA
10.00Probing the insulin sensitivity of skeletal muscle cells with Seahorse extra cellular flux technology
Dr Charles Affourtit, Plymouth University, UK
10.50SHUTTLE BUS DEPARTS TO UNIVERSITY HOSPITAL, COVENTRY
11.15Introduction to the XFe Wave Software
Experimental design for intact cells, isolated mitochondria and permeabilized cells using the Seahorse XF Stress test kits and reagents
Mr Alex Liversage, Seahorse Bioscience, UK
12.00PRACTICAL SESSION: Running an experiment using adherent cells on the XF24 analyser
13.00LUNCH
13.40Tour of HMRU (optional)
Dr Tom Barber, Warwick Medical School & University Hospitals Coventry and Warwickshire, UK
14.00Assay Optimizations – Key items to ensure XF assay success
Dr Alex Liversage, Seahorse Bioscience, UK
15.30 COFFEE and QUESTIONNAIRE
16.00One-on-one session: Consulting participants about their specific needs for research projects
17.00 Closing remarks
Professor Victor Zammit, Warwick Medical School, UK
17.50SHUTTLE BUS DEPARTS TO SCARMAN HOUSE, COVENTRY