University of Virginia School of Medicine
PO Box 800739
Charlottesville, VA 22908-0739
(434) 924-5579
Your Legal Name
Curriculum Vitae:
_
University of Vermont 1989-1990
University of Virginia B.A. 1990-1993 Biology
University of Virginia Ph.D. 1993-1999 Neuroscience
University of Virginia 1993- Medicine
Research Rotations:
Carl Haisch, M.D., University of Vermont (1990)
Federico Gonzalez-Fernandez M.D., Ph.D., University of Virginia (1992-1993)
Russell Foster, Ph.D., University of Virginia (1993)
Robert Grainger, Ph.D., University of Virginia (1994)
Federico Gonzalez-Fernandez, M.D., Ph.D., University of Virginia (1995-present)
Honors, Fellowships, and Awards:
Outstanding First-Year Student in General Biology, University of Vermont (1990)
Phi Beta Kappa (1993)
Richard D. Katz Undergraduate Research Symposium Prize,
University of Virginia (1993)
Bachelor of Arts with Distinction, University of Virginia (1993)
Samuel Miller Scholar Award in Biology, University of Virginia (1993)
Fight for Sight Student Fellowship in memory of Albert G. and Herman B. Mosler (1993)
Medical Scientist Training Program Fellowship (1993)
Merit Scholarship, University of Virginia School of Medicine (1993-1997)
Whitfield-Randolph Scholarship Award, University of Virginia (1996)
ARVO/Retina Research Foundation Joseph M. and Eula C. Lawrence Travel
Fellowship Grant (1999)
Ad hoc National Science Foundation reviewer, 1999.
Publications:
1.) _., Kittredge, K.L., Klinger, A.L., Briercheck, D.M., Braiman, M.S., and Gonzalez-
Fernandez, F. (1994). Expression and characterization of the fourth repeat of Xenopus
interphotoreceptor retinoid-binding protein in E. coli. Curr.Eye Res. 13, 391-400.
2.) Hessler, R.B., _., Bukelman, A., Kittredge, K.L., and Gonzalez-Fernandez, F. (1996).
Interphotoreceptor retinoid-binding protein (IRBP) - expression in the adult and
developing Xenopus retina. J.Comp.Neurol. 367, 329-341.
3.) _., Retief, J.D., Van Niel, E., Braiman, M.S., and Gonzalez-Fernandez, F. (1998). Soluble
expression in E. coli of a functional interphtoreceptor retinoid-binding protein module
fused to thioredoxin: Correlation of vitmain A binding regions with conserved domains
of C-terminal processing proteases. Exp.Eye Res. 66, 249-262..
4.) Gonzalez-Fernandez, F., _., Van Niel, E., Braiman, M.S., Okajima, T.L., and Pepperberg,
D.R. (1998). Fourth module of Xenopus interphotoreceptor retinoid-binding protein:
activity in retinoid transfer between the retinal pigment epithelium and rod
photoreceptors. Curr.Eye Res. 17, 1150-1157.
5.) _., Van Niel, E., Cronk, J.W., Kinter, M.T., Sherman, N.E., Braiman, M.S., and Gonzalez-
Fernandez, F. (1998). Arginine to glutamine substitutions in the fourth module of
Xenopus interphotoreceptor retinoid-binding protein. Mol.Vis. 4:30.
vis.org/molvis/v4/p30.
6.) _., Van Niel, E.E., Braiman, M., Bukelman, A., Retief, J.D., and Gonzalez-Fernandez, F.
Relationship of IRBP’s modules to retinoid binding. In revision.
7.) Gonzalez-Fernandez, F., _., Van Niel, E.E., Braiman, M., Bukelman, A., and Retief, J.D.
Xenopus interphotoreceptor retinoid-binding protein: Evolution and function. In revision.
8.) Gelderman, M.P., Gonzalez-Fernandez, F., _., Wiggert, B., Chan, C-C, Vistica, B.P., and
Gery, I. Xenopus IRBP, a phylogenetically remote protein, is uveitogenic in Lewis rats.
In preparation.
Abstracts:
1.) _, Kittredge, K.L., Gonzalez-Fernandez, F. (1993). Expression of the fourth repeat of
Xenopus IRBP in E. coli. Invest.Ophthal.Vis.Sci. 34, 831.
2.) Hessler, R.B., Wagenhorst, B., _., Gonzalez-Fernandez, F. (1993). Expression of
interphotoreceptor retinoid-binding protein (IRBP) in Xenopus and goldfish
photoreceptors. FASEB J. 7, A371.
3.) Van Niel, E.E., _., Cronk, J.W., Atwood, M., and Gonzalez-Fernandez, F. (1994). Functional
domains in IRBP. Invest.Ophthal.Vis.Sci. 35, 1704.
4.) Payman, R., Bukelman, A., _., Redick, J.A., Sheppard, B.L., Gonzalez-Fernandez, F. (1994)
Role of retinal pigment epithelium (RPE) in interphotoreceptor retinoid-binding protein
(IRBP) turnover. Invest.Ophthal.Vis.Sci. 35, 2061.
5.) Gonzalez-Fernandez, F., Baker, E.L., _., Okajima, T.L., Wiggert, B., and Pepperberg, D.R.
(1995). Recombinant IRBP 4th repeat. Invest.Ophthal.Vis.Sci. 36, S6.
6.) _., Yang, L., and Gonzalez-Fernandez, F. (1996). Light stimulates endocytosis of IRBP by
the RPE. Invest.Ophthal.Vis.Sci. 37, S909.
7.) Van Niel, E.E., _., Miller, V.L., Gonzalez-Fernandez, F. (1996) Comparison of expression
systems for recombinant interphotoreceptor retinoid-binding protein (IRBP).
Invest.Ophthal.Vis.Sci. 37, S801.
8.) _., Van Niel, E.E., Braiman, M.S., and Gonzalez-Fernandez, F. (1997). Truncational
mutagenesis of the fourth module of Xenopus IRBP. Invest.Ophthal.Vis.Sci. 38, S3.
9.) Van Niel, E., _., and Gonzalez-Fernandez, F. (1997). Structure/function studies of IRBP
modules expressed as thioredoxin fusion proteins in E. coli. Invest.Ophthal.Vis.Sci. 38,
S4..10.) _., Van Niel, E.E., Braiman, M, Gonzalez-Fernandez, F. (1998). Site-directed mutagenensis of the fourth module of Xenopus IRBP. Invest.Ophthal.Vis.Sci. 39, S422.
11.) Gelderman, M.P., Gonzalez-Fernandez, F., _., Wiggert, B., Chan, C.C., Vistica, B.P., Gery,
I. (1998). Uveitogenic and immunogenic properties of Xenopus IRBP in rats.
Invest.Ophthal.Vis.Sci. 39, S777.
12.) _., Van Niel, E.E., Braiman, M., Gonzalez-Fernandez, F. (1999). Relationship of IRBP’s
modules to retinoid binding. Invest.Ophthal.Vis.Sci. 40, S217.
13.) Casaletto, J.B., Vleugels, R.A., _., Van Niel, E.E., Gonzalez-Fernandez, F. (1999).
Expression of zebrafish interphotoreceptor retinoid-binding protein (IRBP) and its
individual modules in E. coli. 40, S217.
Community Service:
Big brother/little brother program (1993-present)
Hobbies:
Sailing, windsurfing, canoeing, hiking, guitar