Supplemental Digital Content 2

Baseline characteristics of patients

Obese (n=25)
(Mean ± SD) or N(%) / Healthy Weight (n=25)
(Mean ± SD) or N(%) / P-value
Age* (Years) / 9.91 ± 3.89 / 9.90 ± 3.86 / N/A
Sex*
Male
Female /
18 (72)
7(28) /
18 (72)
7 (28) /
N/A
N/A
Race
Caucasian
African-American
Hispanic/Latino
Other/Unknown /
3 (12)
1 (4)
19 (76)
2 (8) /
11 (44)
2 (8)
12 (48)
0 (0) /
<0.05
0.62
<0.05
0.25
BMI (kg/m2) / 26.45 ± 4.31 / 17.30 ± 2.73 / <0.05
BMI (Percentile) / 98.08 ± 1.38 / 46.1 ± 27.6 / <0.05
Primary indication*
Appendectomy
Pneumonia /
24 (96)
1 (4) /
24 (96)
1 (4) /
N/A
N/A
Initial CrCl (mL/min/1.73m2) / 129 ± 39
(n=19) / 166 ± 54
(n=22) / <0.05

*Matched category

Abbreviations: SD (standard deviation), n or N (number of patients), N/A (not applicable), BMI (body mass index), CrCl (creatinine clearance)