Supplementary material
S6 – U7-specific SM-like proteins: Lsm10 and Lsm11
Lsm10 sequences
>gi|14249632|Lsm10_Homo sapiens
MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
NCK
>gi|109002008|Lsm10_Macaca mulatta
MALSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPSK
NYK
>gi|55586816|Lsm10_Pan troglodytes
MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYT
DRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPK
N
>gi|20270251|Lsm10_Mus musculus
MALSHSVKERTISENSLIILLQGLQGQITTVDLRDESVARGRIDNVDAFMNIRLANVTYT
DRWGHQVELDDLFVTGRNVRYVHIPDGVDITATIEQQLQIIHRVRNFGGKGQGRREFPSK
RP
>gi|34871191|Lsm10_Rattus norvegicus
MALSHSVKERTISENSLIILLQGLQGQITTVDLRDESVARGRIDNVDAFMNIRLANVTYT
DRWGHQVELDDLFVTGRNVRYVHIPDGVNITATIEQQLQIIHRVRNFGGKGQGRREFPSK
RP
>gi|57096594|Lsm10_Canis familiaris
MAVSHSVKERTISENSLIILLQGLQGQVTTVDLRDESVARGRIDNVDAFMNIRLANVTYT
DRWGHQVELDDLFVTGRNVRYVHIPDDVNITATIEQQLQVIHRVRNFGSKGQGRREFPSK
KYK
>gi|76614580|Lsm10_Bos taurus
MEVSHSVKERTISENSLIILLQGLQGQVTTVDLRDESVAHGRIDNVDAFMNIRLAQVTYT
DRWGHQVELDDLFVTGRNVRYVHIPDNVNITATIEQQLQVIHRVRYFGSKGQGRQEFPSK
NS
>gi|50759758|Lsm10_Gallus gallus
MEVSHSVKERTIAENSLVILLQGLHGHVTTVDLRDESTATGRVANVDAFMNMRLAEVTFT
DRRGEVSQLDEIFVTGRNVRYVHIPDEVDIRATIERQLQAIHRVRYFGGRDKGRREFPRA
KHK
>gi|62858991|Lsm10_Xenopus tropicalis
MEVSHSVKERTISENSLIILLQGLHGHVTTVELRDESSATGTITNVDAFMNIRLAKVTYR
DRRERETELDDLFITGRNIRYVHIPEEVDVIHTIENQLRKIQTVRGFGGTGRKEFARRKP
K
>gi|zK206D17|Lsm10_Danio rerio
MDVSHSIRERTIAENSLVILLQGLHGQVTTVDLRDESTARGRVINVDAFMNIRLENVLYR
DRRGRKSSMDDLFITGRNVRYVHIPDQINIIETIEAQLSKIHRVRNFGAGGGRKEYSKKK
>lcl|contig_2132|Lsm10_Gasterosteus acuelateus
VFNSIRERAIAENSMVVLLQGLQGEVTTVDLRNESTARGRVVNVDAFMNVRLEDVLYRDR
RGKLTELQDLFITGRNVRYVHIPDHVDIMKTMQSQLAKIHRVRNFASHGGGRKEYAKK
>gi|252_3|Lsm10_Fugu rubripes
MESQENEPNPSGSGEVISSIRERTVTENSLVVLLQGLQGEVTTVDLRNECTARGRIINVD
AFMNIRLEAVLYRDRRGQIANLQDLFVTGRNVRYVHIPDHVDIMRTIQTQLARIRRVRNF
AREGGGRKEFAKKKN
>gi|47212040|Lsm10_Tetraodon nigroviridis
SIRERTMAENSLVVLLQGLQGEVTTVDLRNECTARGRIVSVDAFMNMRLEAVLYRDRRGQ
LANMQDLFVTGRNVRYVHVPDHVDMMKTIEMQLAKIHRVRNFAQEGGGRKEFAKK
>gi|2497|Lsm10_Ciona intestinalis
MAASSREKFYANNTLAVLLIAMENNNVRVETKNESLIKGRLINCDGFGNLNLINATIINV
RGTKIKVDEIYIKASSVRYVQLPSKINPIEEIEKHISRSKQRKPQMPAKYKKEKT
>gi|21703324|Lsm10_Boltenia villosa
MAASKKERFFKYNTLAILLCGMEGKLITVEMKNDTTITGTLXCVDGFMNMFMKKAKISSC
NGTSMSAERIHVKASNTRYIMLPNDVNPVTAIRQQLNNQT
>gi|115725270|Lsm10_Strongylocentrotus purpuratus
MAPTLSMREKYKSKHTMVCLLRAVVGRITTVELRNECSATGYVVDVDGFMNVTMSKVLFV
NMDGEKTHMDSIFIQASLVRYVQIPDDINMVKAMKKELMMMNPRRPLPGSMAGGRKKPPL
KLCD
>lcl|27988|Lsm10_Branchiostoma floridae
MASLRERAISQNTLVCLLQAIQGHETTVELRDEASVFGLIVNVDAFMNTTMKYCTYTDHR
GKTMQFDDFYVQGRNIRFVQIPDAVNMMEAIEYQLGSIERRRTQHSQERKKMMALREERR
RKREAKSKKT
>gi|39595126|Lsm10_Caenorhabditis elegans
MDSDLKKEEEKKALEAEKRKKTEKERLLAGCGSVLQGMAGKNVAVELRGDNYVIGELVDC
DSDLNIQLKNVTVIRDSQETKEPVYYVTGKFIRFVHFKDQVNVQAAIKRCARGDRAVNGN
RRADQKQFDTGKKLVDQ
>gi|33300397|Lsm10_Caenorhabditis elegans
MEFSNEKKRLESGCGAVLQGMAGKKVFVELRNDVYVIGILESCDSNLDIRIQYATIIRDA
QKTEEPEYLVIGKHVRFVHFEHQVVPIAAIRRCMKGDQTGRPKQNRRLDQKQFDTGRKIV
DQ
>gi|108870086|Lsm10_Aedes aegypti
MSRLTERKERYNTLNELAGLVQCLVNRNILIDLRNESSVAGKITNVDGFMNISMENVVLI
DQLGKHFRMEEFMIYPRYVRYIHIPESIEIVPALEEHIKRETTRKPRAPVKRTYKMKRAQ
LNQQRTLAELNAAQSETSKEQ
>gi|110751095|Lsm10_Apis mellifera
MISESKEERYFYFNSLAILLKAVENVRTIIDLRNEASVYGIVEHADAYMNIVMKDCIFID
PRGDSYNYDMFFVQARNIRFVHIPPKVFLYL
>gi|24652555|Lsm10_Drosophila melanogaster
MQQFSAREKYLVSNTLNCWPVMLQGHSVLIDLHNETSVAGIIDVADGHMTCELTHAVFID
RNGGQHPFDHFMVRNRMIRQIHIPSYLDAEQELRSAMERGVLRRKRVETKGGKRTFKQKR
AEVRHKETLQMISQQKKNKET
>gi|AADE01000005.1|Lsm10_Drosophila pseudoobscura
MQKFSSQEKYLIANTLNCWPVMLQGHSVLMDLRNETSVAGVVDIADGHMTCELSNAVLID
RNGGQHPFDNFMVRNRMIRQIHIPADIDVAQELRQAMEHGVLRRNRVDGRNTKRTFKQKR
AEMRHKETLEMIAQQRSEKEQNQSNIQ
>gi|112998|Lsm10_Nematostella vectensis
MAGRERAIAERSLVCLIKAVQGYNTTVELRNESYLEGFIEHVDGFMNIKMKDVKFVKASG
EVDNLPAMFVVGTQIRYVHIPDEIDMRKAIEQELGKIQGTRTVKRERKMKKRKI
>gi|DDB0189212|Lsm10_Dictyostelium discoideum
MSITYKKDEKDLKNNTNNSKKKFIAKEFQSLLCVFTALRGTQITIQLRSNCEIYGTITNV
DAYLNIELSDAKLTNTRYKNKRDEHVQEILIQSRNIRFIQIPDKIDLNSLLYLYSKQLSQ
SKKKYERTLRKPPPPTK
>lcl|scaffold2|Lsm10_Oryzias_latipes
VEVVNSIRERTIAENSMVVLLQGLQGEVTTVDLRDESSARGLVLNVDAFMNIRLKDVLFL
DRRGQTAQLQDLFITGRNVRYVHIPDHVDIMKTMESQLAKIHRVRNFAGEGGGRKEFGGR
K
Lsm10 alignment
CLUSTAL FORMAT for T-COFFEE Version_1.37, CPU=0.00 sec, SCORE=40, Nseq=25, Len=192
gi|14249632|Homo ------MAVSHS---VKERTISEN------SLIILLQGLQGRVTT
gi|109002008|Macaca ------MALSHS---VKERTISEN------SLIILLQGLQGRVTT
gi|55586816|Pan ------MAVSHS---VKERTISEN------SLIILLQGLQGRVTT
gi|20270251|Mus ------MALSHS---VKERTISEN------SLIILLQGLQGQITT
gi|34871191|Rattus ------MALSHS---VKERTISEN------SLIILLQGLQGQITT
gi|57096594|Canis ------MAVSHS---VKERTISEN------SLIILLQGLQGQVTT
gi|76614580|Bos ------MEVSHS---VKERTISEN------SLIILLQGLQGQVTT
gi|50759758|Gallus ------MEVSHS---VKERTIAEN------SLVILLQGLHGHVTT
gi|62858991|Xenopus ------MEVSHS---VKERTISEN------SLIILLQGLHGHVTT
gi|zK206D17|Danio ------MDVSHS---IRERTIAEN------SLVILLQGLHGQVTT
lcl|contig_2132|Gasterosteus ------VFNS---IRERAIAEN------SMVVLLQGLQGEVTT
gi|252_3|Fugu MESQENEPNPSGSGEVISS---IRERTVTEN------SLVVLLQGLQGEVTT
gi|47212040|Tetraodon ------S---IRERTMAEN------SLVVLLQGLQGEVTT
gi|2497|Ciona ------MAAS---SREKFYANN------TLAVLLIAMENNNVR
gi|21703324|Boltenia ------MAAS---KKERFFKYN------TLAILLCGMEGKLIT
gi|115725270|Strongylocentrotus ------MAPTLS---MREKYKSKH------TMVCLLRAVVGRITT
lcl|27988|Branchiostoma ------MAS---LRERAISQN------TLVCLLQAIQGHETT
gi|39595126|Caenorhabditis MDSDLKKEEEKKALEAEKRKKTEKERLLA------GCGSVLQGMAGKNVA
gi|33300397|Caenorhabditis ------MEFS------NEKKRLES------GCGAVLQGMAGKKVF
gi|108870086|Aedes ------MSRLTE---RKERYNTLN------ELAGLVQCLVNRNIL
gi|110751095|Apis ------MISES---KEERYFYFN------SLAILLKAVENVRTI
gi|24652555|Drosophila ------MQQFS---AREKYLVSN------TLNCWPVMLQGHSVL
gi|AADE01000005.1|Drosophila ------MQKFS---SQEKYLIAN------TLNCWPVMLQGHSVL
gi|112998|Nematostella ------MA---GRERAIAER------SLVCLIKAVQGYNTT
gi|DDB0189212|Dictyostelium ------MSITYK---KDEKDLKNNTNNSKKKFIAKEFQSLLCVFTALRGTQIT
*: : .
gi|14249632|Homo VDLRDESVAHGRIDNVDAFMNIRLAKVTYTDR---WGHQVKLDDLFVTGRNVRYVHIPDD
gi|109002008|Macaca VDLRDESVAHGRIDNVDAFMNIRLAKVTYTDR---WGHQVKLDDLFVTGRNVRYVHIPDD
gi|55586816|Pan VDLRDESVAHGRIDNVDAFMNIRLAKVTYTDR---WGHQVKLDDLFVTGRNVRYVHIPDD
gi|20270251|Mus VDLRDESVARGRIDNVDAFMNIRLANVTYTDR---WGHQVELDDLFVTGRNVRYVHIPDG
gi|34871191|Rattus VDLRDESVARGRIDNVDAFMNIRLANVTYTDR---WGHQVELDDLFVTGRNVRYVHIPDG
gi|57096594|Canis VDLRDESVARGRIDNVDAFMNIRLANVTYTDR---WGHQVELDDLFVTGRNVRYVHIPDD
gi|76614580|Bos VDLRDESVAHGRIDNVDAFMNIRLAQVTYTDR---WGHQVELDDLFVTGRNVRYVHIPDN
gi|50759758|Gallus VDLRDESTATGRVANVDAFMNMRLAEVTFTDR---RGEVSQLDEIFVTGRNVRYVHIPDE
gi|62858991|Xenopus VELRDESSATGTITNVDAFMNIRLAKVTYRDR---RERETELDDLFITGRNIRYVHIPEE
gi|zK206D17|Danio VDLRDESTARGRVINVDAFMNIRLENVLYRDR---RGRKSSMDDLFITGRNVRYVHIPDQ
lcl|contig_2132|Gasterosteus VDLRNESTARGRVVNVDAFMNVRLEDVLYRDR---RGKLTELQDLFITGRNVRYVHIPDH
gi|252_3|Fugu VDLRNECTARGRIINVDAFMNIRLEAVLYRDR---RGQIANLQDLFVTGRNVRYVHIPDH
gi|47212040|Tetraodon VDLRNECTARGRIVSVDAFMNMRLEAVLYRDR---RGQLANMQDLFVTGRNVRYVHVPDH
gi|2497|Ciona VETKNESLIKGRLINCDGFGNLNLINATIINV---RGTKIKVDEIYIKASSVRYVQLPSK
gi|21703324|Boltenia VEMKNDTTITGTLXCVDGFMNMFMKKAKISSC---NGTSMSAERIHVKASNTRYIMLPND
gi|115725270|Strongylocentrotus VELRNECSATGYVVDVDGFMNVTMSKVLFVNM---DGEKTHMDSIFIQASLVRYVQIPDD
lcl|27988|Branchiostoma VELRDEASVFGLIVNVDAFMNTTMKYCTYTDH---RGKTMQFDDFYVQGRNIRFVQIPDA
gi|39595126|Caenorhabditis VELRGDNYVIGELVDCDSDLNIQLKNVTVIR----DSQETKEPVYYVTGKFIRFVHFKDQ
gi|33300397|Caenorhabditis VELRNDVYVIGILESCDSNLDIRIQYATIIR----DAQKTEEPEYLVIGKHVRFVHFEHQ
gi|108870086|Aedes IDLRNESSVAGKITNVDGFMNISMENVVLIDQ---LGKHFRMEEFMIYPRYVRYIHIPES
gi|110751095|Apis IDLRNEASVYGIVEHADAYMNIVMKDCIFIDP---RGDSYNYDMFFVQARNIRFVHIPPK
gi|24652555|Drosophila IDLHNETSVAGIIDVADGHMTCELTHAVFIDR---NGGQHPFDHFMVRNRMIRQIHIPSY
gi|AADE01000005.1|Drosophila MDLRNETSVAGVVDIADGHMTCELSNAVLIDR---NGGQHPFDNFMVRNRMIRQIHIPAD
gi|112998|Nematostella VELRNESYLEGFIEHVDGFMNIKMKDVKFVKA---SGEVDNLPAMFVVGTQIRYVHIPDE
gi|DDB0189212|Dictyostelium IQLRSNCEIYGTITNVDAYLNIELSDAKLTNTRYKNKRDEHVQEILIQSRNIRFIQIPDK
:: :.: * : *. : : * : .
gi|14249632|Homo VNITSTIEQQLQIIHRVRNFGGKGQG------RWEFPPKNCK------
gi|109002008|Macaca VNITSTIEQQLQIIHRVRNFGGKGQG------RWEFPSKNYK------
gi|55586816|Pan VNITSTIEQQLQIIHRVRNFGGKGQG------RWEFPPKN------
gi|20270251|Mus VDITATIEQQLQIIHRVRNFGGKGQG------RREFPSKRP------
gi|34871191|Rattus VNITATIEQQLQIIHRVRNFGGKGQG------RREFPSKRP------
gi|57096594|Canis VNITATIEQQLQVIHRVRNFGSKGQG------RREFPSKKYK------
gi|76614580|Bos VNITATIEQQLQVIHRVRYFGSKGQG------RQEFPSKNS------
gi|50759758|Gallus VDIRATIERQLQAIHRVRYFGGRDKG------RREFPRAKHK------
gi|62858991|Xenopus VDVIHTIENQLRKIQTVRGFG--GTG------RKEFARRKPK------
gi|zK206D17|Danio INIIETIEAQLSKIHRVRNFGA-GGG------RKEYSKKK------
lcl|contig_2132|Gasterosteus VDIMKTMQSQLAKIHRVRNFASHGGG------RKEYAKK------
gi|252_3|Fugu VDIMRTIQTQLARIRRVRNFAREGGG------RKEFAKKKN------
gi|47212040|Tetraodon VDMMKTIEMQLAKIHRVRNFAQEGGG------RKEFAKK------
gi|2497|Ciona INPIEEIEKHISR-SKQR------KPQMPAKYKKEKT------
gi|21703324|Boltenia VNPVTAIRQQLN--NQT------
gi|115725270|Strongylocentrotus INMVKAMKKELMMMNPRRPLPGSMAG------GRKKPPLKLCD------
lcl|27988|Branchiostoma VNMMEAIEYQLGSIERRRTQHSQER------KKMMALREERRRKREAKSKKT------
gi|39595126|Caenorhabditis VNVQAAIKR---CARGDRAVNGNRRA------DQKQFDTGKKLVDQ------
gi|33300397|Caenorhabditis VVPIAAIRRCMKGDQTGRPKQNRRL------DQKQFDTGRKIVDQ------
gi|108870086|Aedes IEIVPALEEHIKR-ETTRKPRAPVKRTYKMKRAQLNQQRTLAELNAAQSETSKEQ-----
gi|110751095|Apis VFLYL------
gi|24652555|Drosophila LDAEQELRSAMERGVLRRKRVETKGG------KRTFKQKRAEVRHKETLQMISQQ
gi|AADE01000005.1|Drosophila IDVAQELRQAMEHGVLRRNRVDGRN------TKRTFKQKRAEMRHKETLEMIAQQ
gi|112998|Nematostella IDMRKAIEQELGKIQGTRTV------KRERKMKKRKI------
gi|DDB0189212|Dictyostelium IDLNSLLYLYSKQLSQSKK------KYERTLRKPPPPTK------
:
gi|14249632|Homo ------
gi|109002008|Macaca ------
gi|55586816|Pan ------
gi|20270251|Mus ------
gi|34871191|Rattus ------
gi|57096594|Canis ------
gi|76614580|Bos ------
gi|50759758|Gallus ------
gi|62858991|Xenopus ------
gi|zK206D17|Danio ------
lcl|contig_2132|Gasterosteus ------
gi|252_3|Fugu ------
gi|47212040|Tetraodon ------
gi|2497|Ciona ------
gi|21703324|Boltenia ------
gi|115725270|Strongylocentrotus ------
lcl|27988|Branchiostoma ------
gi|39595126|Caenorhabditis ------
gi|33300397|Caenorhabditis ------
gi|108870086|Aedes ------
gi|110751095|Apis ------
gi|24652555|Drosophila KKNKET------
gi|AADE01000005.1|Drosophila RSEKEQNQSNIQ
gi|112998|Nematostella ------
gi|DDB0189212|Dictyostelium ------
Lsm11 sequences
>gi|27735089|Lsm11_Homo sapiens
MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLRTGVRGGGRGRGRARGA
AAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAKEEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELH
RCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
SKSAVEDSTLSRYSQTSTWKLASVWGRADTGRGSHKRSRSVPSSLQASAREESRSELSGRTTRTDGSSVGGTFSRATTLS
RGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|109079567|Lsm11_Macaca mulatta
LFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKLASVWGRGDTDRGSHKRSRSVPSSLQASAREESRSELSGRTTRT
EGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|114603137|Lsm11_Pan troglodytes
MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLRTGVRGGGRGRGRARGA
AAGSGVPAAPGPSGRTRRRPDAPAPDPERIQRLRRLMVAKEEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSPLGELH
RCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEAD
SKSAVEDSTLSRYSQTSTWKLASVWGRADTDRGSHKRSRSVPSSLQASAREESRSELSGRTTRTDGSSVGGTFSRATTLS
RGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|29789219|Lsm11_Mus musculus
MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPA
SAGTSTGTSTGAGSSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGARRQGPGRSKKAPRNVLTRMPLHEGSPLGEL
HRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEA
DSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTL
SRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|109488011|Lsm11_Rattus norvegicus
MGKQLLHVPWKNGSGKADFGSPEQIYAAPWWQQLRSACPWAAAAAAQCRPLAARFLSPAHRLRLAGLSNMEEREWGARSA
RAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTG
AGTSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGSRRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVN
VHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSKKEADSKSAVEDSTLS
RYSQTSTWKVASVWGRGDTDRGSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKP
KVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|73954119|Lsm11_Canis familiaris
MNLFPGRAGGGGGGGGGGEPSADTGCPPAAAPAQCSPEPRLRSAALWRPRSSFPSASACGTFKHERSGAGGEDVVTAPGH
GRPSEAAPPRPPVSAAAGSRSEAAEAARGGSRLLPLGGALPTSAGERRGQLAARSLRILPAEPKRIESPPPDRRKTGSYS
HLEFVTQTAGKRCRMCILIQNVELIFALAVCLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMAL
TDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRGSRRRS
RSVPSSLQASAREESRSEMSGRTTRTEGSSAGGTFSRATTLSRGQPRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHL
AQ
>gi|NC007305_1|Lsm11_Bos taurus
VHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRL
KLQDSSKKETDSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRSSRRRSRSVPSSLQASAREESRSELSGRTTRTEGSSA
GGTFSRATTLSRGPSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ
>gi|50754967|Lsm11_Gallu gallus
MNTPPDAAAAPRGHRALQHRRRPTAPHRPAARVPPVGGSVRCPSPLGSRALRCSAGDAAAPPMGGNTNPERIQRLRSLMV
NAGPEQDAAGSGTARRRRAPRNVLTRMPLHEGSPLGELHRCVRDGVKINVHIRTFKGLRGVCTGFLVAFDKFWNMALTDV
DETYRKPVLGKAFYAEPQLSLTRLFDRLKLQDASVKKGADSKTVSGELALTNDSQTSGWKVGSGRGREEDEREKQKRLGR
GGEKKVPGDGLHLAVRGEADVGSGTAHMGGATAGGTRTRSQARRKRRPKVDYQQGNAIL
>gi|33324899|Lsm11_Xenopus laevis
MAEEEDEAPGSCLDVSSESFNPLLALYSPQTPLPFPDIRCFNNLAEYESFLRGGARGRARGAQRGQSRGPGGKRKGRKPE
PDPERIERLKQLMLPVEEGKVPVRPRRSRAPKNVLTRMPLHAGSPLGELNRCVQDRIRIRVHIRTFKGLRGVCSGFIVAF
DKFWNMAMVDVDETYRKPVLGKAFYNEPQLTLTRLFDRLQLQEPGSHDPAKGRPAGPAETLTAPPSKKSTQPSERAAGPP
VEPGPQGHSGNRPKQRRRNRKEKVDYQQVFTRHLKQIFIRGENVLLVHIAE
>gi|62204641|Lsm11_Danio rerio
MEEGERKSESVRCPASSQTSDQQNTTESTGQNPETDEDDVETKLDIRSDKFDPLLALYSPQVPLPYPNIKCFN
NIAEYESFMKGGRGRAKPENVEKRLRKAQKGKADPERIERLKRLMVNNPVPEEGEGSGVKRPPRQRKTAKNVLTRMPLHT
GSPLGQLNRCVQEKIRVKVHIRTFKGLRGVCSGFVVAFDKFWNLAMVDVDETYREPLLGQALYHEKALTITRLFEKLKVQ
ETAALSAVERKQGDKLLKSDPRSGSSQLKDQSRRSDSRHNKEKPELSEIDKSTSSREMQKPESRPKVEYGRVHTRHVNQL
FIRGENVLLVNIQQD
>lcl|contig_5939|Lsm11_Gasterosteus acuelateus
KTDVCSGNFDPLVALYAPAVPLPFPNIRGFNNVAAYESFMKGGRGRAKPENVEKRRRKAMKGVADPERIARLKKLIVNNP
VSETGESSSGGGGGGRRRRQKPQKNVLTRMPLCKGSPMGELYRCVEERIRVKVHIRTFKGLRGVCSGFVVAFDKFWNMAM
VDVDETYREPLLGEAFYHEKALTISRV
>gi|544|Lsm11_Fugu rubripes
QIDVCSDKFDPLMALYSPTVSIPFPKIKCFNNVSEYESFLKGGRGRAKPENVEKKRLKAMKGVADPERIERLKRLMVNNP
VAESEGGESSSAPQRRRQKVQKNVLTRMPCEGSPLGELYRCVQERIRVKVHIRTFKGLRGVCSGFVVAFDKFWNMAMVDV
DETYREPLLGEAFYHEKALTISRLFEKLKLQESPAGSQPTAKPDEGETVRSHLPVQDPGRREQSSTGAGLSHGLGTKYKD
SPKAREENNATKPGKCHTRHINQLFIRGENVILVNPQRL
>gi|47216812|Lsm11_Tetraodon nigroviridis
QIDVCSDKFDPLLALYSPTVSIPFPEIKCFNNVSEYESFLKGGRGRAKPENVEKKRRKAMKGVADPERIERLKKLVVDNP
VEESDGAGSSSTSRSRRRRPQKNVLTRMPLCEGSPLGELYRCVQEGIRVKVHIRTFKGLRGFCSGFVVAFDKFWNMAMVD
VDETYREPLRGEAFYHEKALTISRLFEKLKLQESPAGSRPTRKAEAGESVSAHRPAPDAGGPEQSPAGAGLSDSVRTPNK
GCEKKDGKSFGKVHTRHIRQLFIRGENVILVNPQRL
>lcl|525|Lsm11_Ciona intestinalis
MATDPSSSDFDPLLALYPTEVISHEPGLKVYDNIQIFEANQQQRETAKVQKTKQNENKLKSFSQRRKIQEEVNKRDVTML
QLMMQQKKNQRPELIDKTEKMKETRKEKTLSTIFTSMEKLSEGPFSVLHRITNDRARCKVFTRNFCGLRGVLCGYVVAYD
RFMNMVMVDVDETFCKSPLGGVAQHQQRMSTFKLNSAVKDISLYGVKGSATSIGINEVPRHTVAQGGQPPLFHRHLTNLY
VRGDSVILISI
>lcl|Scaffold97769|Lsm11_Strongylocentrotus purpuratus (partial)
SPLDLLRQCVEKRCKVRVCIRSFKGLRSICIGYLVAFDKIWNMALTDVVEIYKRPSTGKRFHHEEKVT
>lcl|5039|Lsm11_Branchiostoma floridae
MEPEEEEAVDLTSPDFDPAKALSSQAVSLPVPNVRPFENLAQYESAMKGLRARRKAPASTQHGGPDTAGKSGSKDSSTEA
GPSARSLPPLVATHRKPAKTLLTRMTEAKQGPLDVLRSCISEKRRVIVTTRTFKGLRGICTGYLVAFDKFWNLAMADVEE
VYHKPPLGKKFFNEETLTVSKVFLENEYSSLKKHGRERDKGSKAGPESLSALESKLTNLQKELAALDAEESDEEEDTGTK
AKTRRKPRKQECQFFKRHVNQLFVRGENVVIVSIKDA
>gi|108883342|Lsm11_Aedes aegypti
MRSAIMSESDESNSEGSRGSSGRDGDSSSEGSPTELDPTSAGFKPLRVLYSRKPQAVPIPEAKLLDNVGMFESRFSQLGG
FDQRYSDQRLKEIFQARAATSKRAQMQLASTSGSGAEMPQRRFLPHQEMIKAEKPARLRRNILVKLERTEGPLKLMMTWM
RERVRVRVYTRRKSGVRGYVTGFVEMFDKHWNMALVDVYESWKRRKYRYSENKLCVLGQAEDCSALLREMGIRVPEVSVQ
SAGRKYVTCSRRMPKLMIRGEQVVLVTKDSEKVGKEDEEKKVE
>gi|58378512|Lsm11_Anopheles gambiae str. PEST
MGNSDTDSTTSESDSSGELDVGSKRFNPLKALYSAKLKVPVPKARLHDNISSLEGKQLTLGGFTEKFDEARIRQIRAAQN
KPKLAENEMPQRRFLPEQGPVTRVRSIRHTKNIFIRLEKGFEGPLGQLQRWMEGRNRVRVSIRKQKGVRGHVSGVLELFD
KHWNLALSDVCETWTRRKYRYSENRQHPDSMEAPRDCSERLRRLGIVLPELKVRPADGKKNVIITRKVPQLLVKGEMVVL
VTLEPGEPQASTSKGTK
>gi|NC007072_1|Lsm11_Apis mellifera (partial)
LDVKSVKFDPLKALYSTKIKLSGTKAPIYDNVSKFEAVMSGKVYTRNARGIRGHVEAYVAAFDKHWNLALEDCFEIWTRK
VKRKA
>gi|21430742|Lsm11_Drosophila melanogaster
MESRDRKTSNEDDSSEISELDVGSDRFNPLRALYEPNFRVTDAVPKVIYQNLAAFESALKKFGIWQLNKRQKPGSAEGGD
QGTSKKASTSEAVDILPPERRFEPHQMPTTSSRKKHHRNIFTYMEAAVGPLELLTKCISPASHNESNERIRVRVVIRKHG
SVGGSVEGELLAFDKQWNLLLRNVTETWKRRKYNYGEQNICDTPVDCTGRLKELGITLPRTVVKNLNRKNVEIRRELPQI
LIRGENVVLVSLIPTK
>gi|AADE01000118|Lsm11_Drosophila pseudooscular
ELDVCSEHFNPLRALYEPNYKITDVPPKVLYQNLAAFESALKKFGVWQLNKRQKSGTSAGPGQADQKSSLPCTSKTVMVL
EEAPQRRFEPHQMPMVSTVNKKHQRNIFTYMETTVGPLELLKKCIVSPALENNSKFRVRVVIRKEREIGGRVEGELVAYD
KQWNLLLRNATETWKRRKYNFGEQKLCGAPVDCSARLRDLGIVLPTVEVKSLNRKNVQVKRDLPQVLIRGENVVLISLI
>lcl|DDB0188426|Lsm11_Dictyostelium discoideum
MDNLKSKNKGNGGGDHDNYGNDNDKFNVLSDKFDALLALKNPQLVSLPFPKIKPLDNIHKARILLPPSDENYVQIKKPPT
QPINNINITSLNNNNSSTTTNTSPPIESTPTTTTTTTTTTTTSTTSTNSIASIVETTTTTTTIRKKNTNEDHKILKNISN
KFTDGPLSLLKRALESKSKIKVMIRGTNCIRGYCRGYIIAFDKHMNIILRDVEEEYDLLKSLPSTRNQNQPIQPKIKRYY
GQLFIKGDTVVSVILID
>lcl|scaffold18|Lsm11_Oryzias_latipes
NVTEATSAEGATGRDNESSDPADKINVCSDNFDPLLALYSSTAPPLPFPNIKCFNNVAEYESFLKGGRGRAKPENVEKRR
RKALKGVADPERIDRLRKLMVSSSQEGEGSTAKPRRKQKILKNVLTRMPLCKGSPLGELHRCIQERIRIKVHIRTFKGMR
GVCSGFLVAFDKFWNMAMVDVDETYREPLFGEALYHEKALTISRLFEKLNLQESPGGTDVQEKADQHPPANPRAAPESCF
AQMEGDGATSQSDLPEAIKSKQGKLQVSLKAKDPHMHPKGESQKYGKVYTRHINQLFIRGENVILVNPQ
Lsm11 alignment
CLUSTAL FORMAT for T-COFFEE Version_1.37, CPU=0.00 sec, SCORE=29, Nseq=22, Len=475
gi|27735089|Homo ------
gi|109079567|Macaca ------
gi|114603137|Pan ------
gi|29789219|Mus ------
gi|109488011|Rattus MGKQLLHVPWKNGSGKADFGSPEQIYAAPWWQQLRSACPWAAAAAAQCRPLAARFLSPAH
gi|73954119|Canis ------MNLFPGRAGGGGGGGGGGEPSADTGCPPAAAPAQCSPEP
gi|NC007305_1|Bos ------
gi|50754967|Gallu ------
gi|33324899|Xenopus ------
gi|62204641|Danio ------MEEGERKSESV
lcl|contig_5939|Gasterosteus ------
gi|544|Fugu ------
gi|47216812|Tetraodon ------
lcl|525|Ciona ------
lcl|Scaffold97769|Spurpuratus ------
lcl|5039|Branchiostoma ------
gi|108883342|Aedes ------MRS
gi|58378512|Anopheles ------
gi|NC007072_1|Apis ------
gi|21430742|Drosophila ------
gi|AADE01000118|Drosophila ------
lcl|DDB0188426|Dictyostelium ------
gi|27735089|Homo ------MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPY-PNA
gi|109079567|Macaca ------
gi|114603137|Pan ------MEERERGARSAGAGSPARPPSPRLDVSSDSFDPLLALYAPRLPPIPY-PNA
gi|29789219|Mus ------MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPY-PNA
gi|109488011|Rattus RLRLAGLSNMEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPY-PNA
gi|73954119|Canis RLRSAALWRPRSSFPSASACGTFKHERSGAGGEDVVTA---PGHGRPSEAAPPRP--PVS
gi|NC007305_1|Bos ------
gi|50754967|Gallu ------MNTPPDAAAAP-RGHRALQHRRRPTAPHRPAA
gi|33324899|Xenopus ------MAEEEDEAPGSCLDVSSESFNPLLALYSPQTP-LPF-PDI
gi|62204641|Danio RCPASSQTSDQQNTTESTGQNPETDEDDVETKLDIRSDKFDPLLALYSPQVP-LPY-PNI
lcl|contig_5939|Gasterosteus ------KTDVCSGNFDPLVALYAPAVP-LPF-PNI
gi|544|Fugu ------QIDVCSDKFDPLMALYSPTVS-IPF-PKI
gi|47216812|Tetraodon ------QIDVCSDKFDPLLALYSPTVS-IPF-PEI
lcl|525|Ciona ------MATDPSSSDFDPLLALYPTEV-ISHE-PGL
lcl|Scaffold97769|Spurpuratus ------
lcl|5039|Branchiostoma ------MEPEEEEAVDLTSPDFDPAKALSSQAVS-LPV-PNV
gi|108883342|Aedes AIMSESDESNSEGSRGSSGRDGDSSSEGSPTELDPTSAGFKPLRVLYSRKPQAVPI-PEA
gi|58378512|Anopheles ------MGNSDTDSTTSESDSSGELDVGSKRFNPLKALYSAKLK-VPV-PKA
gi|NC007072_1|Apis ------LDVKSVKFDPLKALYSTKIK-LSG-TKA
gi|21430742|Drosophila ------MESRDRKTSNEDDSSEISELDVGSDRFNPLRALYEPNFRVTDAVPKV
gi|AADE01000118|Drosophila ------ELDVCSEHFNPLRALYEPNYKITDV-PPK
lcl|DDB0188426|Dictyostelium ------MDNLKSKNKGNGGGDHDNYGNDNDKFNVLSDKFDALLALKNPQLVSLPF-PKI
gi|27735089|Homo PCFNNVAEYESFLRTGVRGGGRGRGRA--RGAAAGSGVPAAPGPSGRTRRR------
gi|109079567|Macaca ------
gi|114603137|Pan PCFNNVAEYESFLRTGVRGGGRGRGRA--RGAAAGSGVPAAPGPSGRTRRR------
gi|29789219|Mus PCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAG-SSSRARR------
gi|109488011|Rattus PCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAG-TSSRARR------
gi|73954119|Canis AAAGSRSEAAEAARGGSRLLPLGGALPTSAGERRGQLAARSLRILPAEPKR------
gi|NC007305_1|Bos ------
gi|50754967|Gallu RV------PPVGGSVRCPSPLGSRALRCSAGDAAAPPMG------
gi|33324899|Xenopus RCFNNLAEYESFLRGGARGRARGAQRGQSRGPGG------KRK------
gi|62204641|Danio KCFNNIAEYESFMKGG------RGRAKPENV------EKRLRK------
lcl|contig_5939|Gasterosteus RGFNNVAAYESFMKGG------RGRAKPENV------EKRRRK------
gi|544|Fugu KCFNNVSEYESFLKGG------RGRAKPENV------EKKRLK------
gi|47216812|Tetraodon KCFNNVSEYESFLKGG------RGRAKPENV------EKKRRK------
lcl|525|Ciona KVYDNIQIFEA------NQQQRETAKVQKTKQNENKLK----SFSQRRK------
lcl|Scaffold97769|Spurpuratus ------
lcl|5039|Branchiostoma RPFENLAQYESAMKG-----LRARRKAPASTQHGGPDTA------
gi|108883342|Aedes KLLDNVGMFESRFSQLGGFDQRYSDQRLKEIFQARAATSKRAQMQLAST------
gi|58378512|Anopheles RLHDNISSLEGKQL-TLGGFTEKFDEARIRQIRAAQNKPK------
gi|NC007072_1|Apis PIYDNVSKFEAVMSG------
gi|21430742|Drosophila -IYQNLAAFESALK--KFGIWQLNKRQKPGSAEGGDQGTSKKASTSE------
gi|AADE01000118|Drosophila VLYQNLAAFESALKKFGVWQLNKRQKSGTSAGPGQADQKSSLPCTSKT------
lcl|DDB0188426|Dictyostelium KPLDNIHKARILLPPSDENYVQIKKPPTQPINNINITSLNNNNSSTTTNTSPPIESTPTT
gi|27735089|Homo -PDAPAPDPERIQRLRRLMV---AKEEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSP
gi|109079567|Macaca ------
gi|114603137|Pan -PDAPAPDPERIQRLRRLMV---AKEEGDGAAGAGRRGPGRSRKAPRNVLTRMPLHEGSP
gi|29789219|Mus -RAAPTPDPERIQRLRRLMV---VKEDTDGTAGARRQGPGRSKKAPRNVLTRMPLHEGSP
gi|109488011|Rattus -RAAPTPDPERIQRLRRLMV---VKEDTDGTAGSRRQGPGRSKKAPRNVLTRMPLHEGSP
gi|73954119|Canis -IESPPPDRRKTGSYSHL------EFVTQTAGKRCRMCILIQNVELIFALAVCLHEGSP
gi|NC007305_1|Bos ------VHEGSP
gi|50754967|Gallu ----GNTNPERIQRLRSLMV------NAGPEQDAAGSGTARRRRAPRNVLTRMPLHEGSP
gi|33324899|Xenopus -GRKPEPDPERIERLKQLML------PVEEGKVPVRPRRSRAPKNVLTRMPLHAGSP
gi|62204641|Danio -AQKGKADPERIERLKRLMV---NNPVPEEGEGSGVKRPPRQRKTAKNVLTRMPLHTGSP
lcl|contig_5939|Gasterosteus -AMKGVADPERIARLKKLIVNNPVSETGESSSGGGGGGRRRRQKPQKNVLTRMPLCKGSP
gi|544|Fugu -AMKGVADPERIERLKRLMVNNPVAESEGGESSSAPQ--RRRQKVQKNVLTRMPC-EGSP
gi|47216812|Tetraodon -AMKGVADPERIERLKKLVV--DNPVEESDGAGSSSTSRSRRRRPQKNVLTRMPLCEGSP
lcl|525|Ciona --IQEEVNKRDVTMLQLMM-QQKKNQRPELIDKTEKMKETRKEKTLSTIFTSMEKLSEGP
lcl|Scaffold97769|Spurpuratus ------SP
lcl|5039|Branchiostoma -GKSGSKD------SSTEAGPSARSLPPLVATHRKPAKTLLTRMTEAKQGP
gi|108883342|Aedes -SGSGAEMPQR----RFL------PHQEMIKAEKPARLRRNILVKLERTEG-P
gi|58378512|Anopheles --LAENEMPQR----RFL------PEQGPVTRVRSIRHTKNIFIRLEKGFEGP
gi|NC007072_1|Apis ------
gi|21430742|Drosophila --AVDILPPER------RFEPHQMPTTSSRKKHHRNIFTYMEAAVG-P
gi|AADE01000118|Drosophila -VMVLEEAPQR------RFEPHQMPMVSTVNKKHQRNIFTYMETTVG-P
lcl|DDB0188426|Dictyostelium TTTTTTTTTTSTTSTNSIA---SIVETTTTTTTIRKKNTNEDHKILKNISNKF---TDGP
gi|27735089|Homo LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|109079567|Macaca ------
gi|114603137|Pan LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|29789219|Mus LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|109488011|Rattus LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|73954119|Canis LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|NC007305_1|Bos LGELHRCI------REGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|50754967|Gallu LGELHRCV------RDGVKINVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYR
gi|33324899|Xenopus LGELNRCV------QDRIRIRVHIRTFKGLRGVCSGFIVAFDKFWNMAMVDVDETYR
gi|62204641|Danio LGQLNRCV------QEKIRVKVHIRTFKGLRGVCSGFVVAFDKFWNLAMVDVDETYR
lcl|contig_5939|Gasterosteus MGELYRCV------EERIRVKVHIRTFKGLRGVCSGFVVAFDKFWNMAMVDVDETYR
gi|544|Fugu LGELYRCV------QERIRVKVHIRTFKGLRGVCSGFVVAFDKFWNMAMVDVDETYR
gi|47216812|Tetraodon LGELYRCV------QEGIRVKVHIRTFKGLRGFCSGFVVAFDKFWNMAMVDVDETYR
lcl|525|Ciona FSVLHRIT------NDRARCKVFTRNFCGLRGVLCGYVVAYDRFMNMVMVDVDETFC
lcl|Scaffold97769|Spurpuratus LDLLRQCV------EKRCKVRVCIRSFKGLRSICIGYLVAFDKIWNMALTDVVEIYK
lcl|5039|Branchiostoma LDVLRSCI------SEKRRVIVTTRTFKGLRGICTGYLVAFDKFWNLAMADVEEVYH
gi|108883342|Aedes LKLMMTWM------RERVRVRVYTRRKSGVRGYVTGFVEMFDKHWNMALVDVYESWK
gi|58378512|Anopheles LGQLQRWM------EGRNRVRVSIRKQKGVRGHVSGVLELFDKHWNLALSDVCETWT
gi|NC007072_1|Apis ------KVYTRNARGIRGHVEAYVAAFDKHWNLALEDCFEIWT
gi|21430742|Drosophila LELLTKCI-SPASHNESNERIRVRVVIRKHGSVGGSVEGELLAFDKQWNLLLRNVTETWK
gi|AADE01000118|Drosophila LELLKKCIVSPAL--ENNSKFRVRVVIRKEREIGGRVEGELVAYDKQWNLLLRNATETWK
lcl|DDB0188426|Dictyostelium LSLLKRAL------ESKSKIKVMIRGTNCIRGYCRGYIIAFDKHMNIILRDVEEEY-
gi|27735089|Homo KPVLGKAYERDSSLTLTRLFDRLKLQDSSK-KEADSKSAV-EDSTLSRYSQTSTWKLASV
gi|109079567|Macaca ------LFDRLKLQDSSK-KEADSKSAV-EDSTLSRYSQTSTWKLASV
gi|114603137|Pan KPVLGKAYERDSSLTLTRLFDRLKLQDSSK-KEADSKSAV-EDSTLSRYSQTSTWKLASV
gi|29789219|Mus KPVLGKAYERDSSLTLTRLFDRLKLQDSSK-KEADSKSAV-EDSTLSRYSQTSTWKVASV
gi|109488011|Rattus KPVLGKAYERDSSLTLTRLFDRLKLQDS-K-KEADSKSAV-EDSTLSRYSQTSTWKVASV
gi|73954119|Canis KPVLGKAYERDSSLTLTRLFDRLKLQDSSK-KEADSKSAV-EDSTLSRYSQTSTWKVASV
gi|NC007305_1|Bos KPVLGKAYERDSSLTLTRLFDRLKLQDSSK-KETDSKSAV-EDSTLSRYSQTSTWKVASV
gi|50754967|Gallu KPVLGKAFYAEPQLSLTRLFDRLKLQDASVKKGADSKT-VSGELALTNDSQTSGWKVGSG
gi|33324899|Xenopus KPVLGKAFYNEPQLTLTRLFDRLQLQEP------
gi|62204641|Danio EPLLGQALYHEKALTITRLFEKLKVQETA------ALSAV------
lcl|contig_5939|Gasterosteus EPLLGEAFYHEKALTISRV------
gi|544|Fugu EPLLGEAFYHEKALTISRLFEKLKLQESPA------
gi|47216812|Tetraodon EPLRGEAFYHEKALTISRLFEKLKLQESPA------
lcl|525|Ciona KSPLGGVAQHQQRMSTFKL------NSAVKD------ISL
lcl|Scaffold97769|Spurpuratus RPSTGKRFHHEEKVT------
lcl|5039|Branchiostoma KPPLGKKFFNEETLTVSKVF----LEN------EYSSLKKH------
gi|108883342|Aedes RR---KYRYSENKLCVL------
gi|58378512|Anopheles RR---KYRYSEN------
gi|NC007072_1|Apis RKVKRKA------
gi|21430742|Drosophila RR---KYNYGEQNICDTPV------DC
gi|AADE01000118|Drosophila RR---KYNFGEQKLC------
lcl|DDB0188426|Dictyostelium ------DLLK------
gi|27735089|Homo WGRADTGRGSHKR-----SRSVPSS-LQASAREESRSELSGRTTRTDGSSVGGTFSRATT
gi|109079567|Macaca WGRGDTDRGSHKR-----SRSVPSS-LQASAREESRSELSGRTTRTEGSSVGGTFSRATT
gi|114603137|Pan WGRADTDRGSHKR-----SRSVPSS-LQASAREESRSELSGRTTRTDGSSVGGTFSRATT
gi|29789219|Mus WGRGDTDRSSHRR-----SRSVPSS-LQASAREESRSELSGRTTRTEGSSVGGTFSRATT
gi|109488011|Rattus WGRGDTDRGSHRR-----SRSVPSS-LQASAREESRSELSGRTTRTEGSSVGGTFSRATT
gi|73954119|Canis WGRGDTDRGSRRR-----SRSVPSS-LQASAREESRSEMSGRTTRTEGSSAGGTFSRATT
gi|NC007305_1|Bos WGRGDTDRSSRRR-----SRSVPSS-LQASAREESRSELSGRTTRTEGSSAGGTFSRATT
gi|50754967|Gallu RGREEDEREKQKRLGRGGEKKVPGDGLHLAVRGE--ADVGSGTAHMGGATAGGTRTR---
gi|33324899|Xenopus -GSHDPAKG--RPAGPAETLTAPPS--KKSTQPSERAAGPPVEPGPQGHSG------
gi|62204641|Danio ------ERKQGDKLLKSDPRSGSSQLKDQSRRSDSRHNKEKPELSEI----DKST-
lcl|contig_5939|Gasterosteus ------
gi|544|Fugu -GSQPTAKPDE---GETVRSHLP---VQDPGRREQSSTGAGLSHGL------GTKYKDS-
gi|47216812|Tetraodon -GSRPTRKAE---AGESVSAHRPA---PDAGGPEQSPAGAGLSDSV------
lcl|525|Ciona YG----VKGSATSIG---INEVPRHTVAQ------GG------
lcl|Scaffold97769|Spurpuratus ------
lcl|5039|Branchiostoma -GR-ERDKGS------KAGPESLSALESKLTNLQKELAALDAEESDEEEDT------
gi|108883342|Aedes -GQAEDCSALLREMG----IRVPEVSVQSAGRK------
gi|58378512|Anopheles ------RQHPDS-MEAPRDCSERLRRLGIV------
gi|NC007072_1|Apis ------
gi|21430742|Drosophila TGR------LKELG----ITLPRTVV------
gi|AADE01000118|Drosophila -GAPVDCSARLRDLG----IVLPTVEV------
lcl|DDB0188426|Dictyostelium ------SLPST------
gi|27735089|Homo LSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|109079567|Macaca LSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|114603137|Pan LSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|29789219|Mus LSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|109488011|Rattus LSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|73954119|Canis LSRGQPRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|NC007305_1|Bos LSRGPSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ------
gi|50754967|Gallu ----SQARRKRRPKVDYQQ------GNAIL------
gi|33324899|Xenopus -NRPKQRRRNRKEKVDYQQVFTRHLKQIFIRGENVLLVHIAE------
gi|62204641|Danio -SSREMQKPESRPKVEYGRVHTRHVNQLFIRGENVLLVNIQQD------
lcl|contig_5939|Gasterosteus ------
gi|544|Fugu -PKAREENNATKP----GKCHTRHINQLFIRGENVILVNPQRL------
gi|47216812|Tetraodon --RTPNKGCEKKDGKSFGKVHTRHIRQLFIRGENVILVNPQRL------
lcl|525|Ciona ------QP-----PLFHRHLTNLYVRGDSVILISI------
lcl|Scaffold97769|Spurpuratus ------
lcl|5039|Branchiostoma ---GTKAKTRRKPRKQECQFFKRHVNQLFVRGENVVIVSIKDA------
gi|108883342|Aedes ------YVTC-SRRMPKLMIRGEQVVLVTKDSEKVGKEDEEKKVE
gi|58378512|Anopheles LPELKVRPADGKKNV----IITRKVPQLLVKGEMVVLVTLEPGEPQASTSKGTK-
gi|NC007072_1|Apis ------
gi|21430742|Drosophila ------KNLNRKNVE----IRRELPQILIRGENVVLVSLIPTK------
gi|AADE01000118|Drosophila ------KSLNRKNVQ----VKRDLPQVLIRGENVVLISLI------
lcl|DDB0188426|Dictyostelium ------RNQNQP---IQPKIKRYYGQLFIKGDTVVSVILID------