NIH-CAP 2007-08 Participating Companies
Champaign, IL
Industry Sector: Medical Devices / Everette C. Burdette
Tel: 217-239-0900
Email:
Acoustic MedSystems, Inc. (AMS) focuses on the development of minimally invasive interventional methods for treatment, treatment guidance, and delivery monitoring. These are predominately real-time methods for imaging, image processing and therapy delivery guidance. Included are its proprietary ACOUSTXTM technology (Applicators with Controllable Output of Ultrasound for Selective Treatment) for minimally invasive targeted thermal ablation of tumors and other soft-tissue diseases and its spatially-registered image guidance methodologies for treatment delivery and monitoring. The ACOUSTX technology can provide significant benefits and improvements over traditional surgical procedures, as well as over other minimally invasive thermal technologies, and has treatment potential for a wide range of soft-tissues (malignant and benign tumors, other soft tissue disorders) including breast, liver, uterus, prostate, brain, lung, bladder, and colo-rectal diseases. Additionally, the technology can be effective for the treatment of prostate BPH, uterine fibroids, and stress urinary incontinence. The other core technologies of the company are in image registration and real-time intraoperative treatment guidance and monitoring.
Advanced Brain Monitoring, Inc.
Carlsbad, CA
Industry Sector: Medical Devices / Mandy Sinning
Tel: 760-720-0099
Email:
Advanced Brain Monitoring, Inc. (ABM) is the first company to address sleep apnea, memory dysfunction, and alertness monitoring with instrument systems that combine laboratory level accuracy with the portability, ease of use and low cost of consumer electronics. Patients with conditions targeted by ABM’s products total over 110 million people in the US alone, and the vast majority have not been assisted diagnostically. ABM systems make widespread use by physicians, dentists, industrial/transportation companies, and consumers possible.
Advanced Circulatory Systems, Inc.
Eden Prairie, MN
Industry Sector: Medical Devices / Mike Black
Tel: 952-947-9551
Email:
Advanced Circulatory Systems is focused on developing and commercializing a sudden cardiac arrest resuscitation system. The platform for this system is a combination of proprietary technologies developed by Advanced Circulatory Systems to increase blood flow during CPR and survival rates for cardiac arrest victims. The goal is to create a cost-effective treatment system through an optimized integration of multiple cardiac arrest-related technologies that will significantly improve cardiac arrest survival rates.
AfaSci, Inc.
Carlsbad, CA
Industry Sector: Pharmaceuticals / Xinmin Simon Xie
Tel: 650-784-5658
Email:
AfaSci, Inc. currently develops a wireless, non-invasive rodent homecage monitoring system for in vivo high-throughput screening (HTS) of drug efficacy and safety, and for behavioral phenotyping of transgenic and knockout mice, through collaborations with Pennsylvania State University, Pennsylvania, The George Washington University, Washington, D.C.), and research institutions (SRI International, CA). We provide products and services in these areas.
In the future direction, we will explore contract services on in vivo drug screening and potentially new drug discovery via commercial contracts, collaborations and/or partner with both biotech or pharmaceuticals.
AJ Medical Devices, Inc
Wilmette, IL
Industry Sector: Medical Devices / Robert Arzbaecher
Tel: 847-251-5020
Email:
AJ Medical Devices develops monitoring systems for the high-risk patient that are based on small sensors implanted under the skin that communicate externally via wireless. The first product, CardioAlarm, has an implanted sensor that records a patient’s EKG, automatically detects an abnormal heart rhythm, and transmits an alarm and EKG recording to a 24/7 patient monitoring service, without the encumbrance of electrodes on the skin and wires tethering the patient to a recorder. AJ Medical is seeking capital to complete FDA requirements, begin manufacture and marketing of CardioAlarm, and develop the next in a series of minimally invasive and wireless physiologic monitors.
Akaza Research
Cambridge, MA
Industry Sector: Clinical Research / Cal Collins
Tel: 617-621-8585
Email:
Akaza Research has developed OpenClinica, the leading open source clinical trial data capture and management software platform. Akaza brings Open Source Software (OSS) into the mainstream of the clinical research enterprise by making robust, flexible, standards-based systems accessible for private and public research. Akaza Research provides OpenClinica support, training, and consulting services to its customers worldwide.
Allied Innovative Systems, LLC
Parsippany, NJ
Industry Sector: Diagnostics / Simon Bystryak
Tel: 973-919-5707
Email:
Allied Innovative Systems (ALLIS) is a research and development company engaged in the development of new technologies in the field of biochemical and biomedical assays and reagents. In particular, we have developed several techniques that increase the sensitivity of enzyme-mediated fundamental analytical assays. This work was supported by NIH SBIR grants. Now, we are in the process of negotiations regarding the commercialization of these technologies with a market leader in biomedical diagnostics. Several novel biochemical assays, such as development of new homogeneous analytical assays based on generation of singlet oxygen and detection of fluorescence polarization, were also developed by ALLIS.
Applied Scientific Research
Santa Ana, CA
Industry Sector: Other / Adrin Gharakhani
Tel: 949-752-7545
Email:
Applied Scientific Research (ASR) develops state-of-the-art user-friendly design and analysis software to simulate and visualize thermo-fluid dynamical processes of interest to government and industrial clients in the environmental, bioengineering and medical products sectors, as well as the aerospace, automotive, maritime, and chemical fields. Additionally, ASR provides engineering consulting support to clients in the same fields. At present, ASR has NIH support to develop a highly advanced "virtual test chamber" to investigate blood flow about mechanical heart valves under physiologically realistic flow conditions. Another NIH project supports the development of software for simulating particulate-laden flow, such as flow of platelets and red blood cells in plasma as well as drug particulates or aerosols in carrier fluid streams.
Archimage, Inc.
Houston, TX
Industry Sector: Healthcare Media / Richard Buday
Tel: 713-523-3425
Email:
Archimage is a twenty-four-year-old design studio and winner of over thirty international awards for architecture, television commercials, videogames, websites, and graphic design.The company is wrapping up development of two videogames targeted to preventing obesity and type II diabetes in children.
The rising incidence of type II diabetes has reached epidemic proportions, especially among children and young adults. Causes are linked to poor diet and lack of exercise. Diabetes, the leading cause of new blindness and kidney failure, is also the nation’s sixth leading cause of death. The predicted societal and economic impacts are staggering.
Videogames are one of the fastest-growing businesses in the entertainment world. Research shows a majority of children and teenagers spend an hour a day playing videogames. The average age videogame player is 33 years old.
Archimage believessignificant consumer markets exist for videogames that promote healthy lifestyles.
Atmospheric Glow Technologies, Inc.
Knoxville, TN
Industry Sector: Medical Devices / Kimberly Kelly-Wintenberg
Tel: 865-777-3776
Email:
Atmospheric Glow Technologies, Inc. (AGT) is a science and engineering company developing products based upon patented One Atmosphere Uniform Glow Discharge Plasma (OAUGDP®) technology. The company has assembled an experienced and diverse team of experienced officers and highly trained scientists and engineers committed to technology commercialization. AGT owns two patents and has exclusive rights to eight patents. AGT’s technology uses radio-frequency electric power to generate plasma from air which in turn produces highly oxidative chemical species that can be used beneficially in several application areas. AGT’s plasma doesn’t require special gases or vacuum conditions so it costs less to operate than other plasma technologies. AGT has introduced two products and is working to commercialize other plasma products in the areas of biotechnology, medical device sterilization, air purification, and disinfection of food and other agricultural products.
BioFormatix, Inc.
Escondido, CA
Industry Sector: Diagnostics / Dariusz Wroblewski
Tel: 858-248-2884
Email:
BioFormatix was founded and incorporated in 2004 as a research, product development and service company addressing the needs of biomedical markets. Our technology addresses challenging problems in data collection, data modeling, and software development.
The present product development programs, funded by the NIH National Eye Institute, include:
* Head mounted apparatus for the visual field testing.
* Diagnostic aid software for early detection of glaucoma from the visual field test.
Other current interests include:
* Computerized personal tools for weight management and diabetes management.
* Novel graphical computer interfaces.
* Medical diagnostic aid software.
* Bioinformatics and novel modeling approaches to analysis of molecular expression data (metabonomic, genomic/transcriptomic, proteomic).
BioHesion Inc.
Seattle, WA
Industry Sector: Biotechnology / Theo deVos
Tel: 206-235-3435
Email:
BioHesion has developed expertise in surface chemistry with an emphasis on derivatizing inert surfaces with biomolecules. We have produced a number of recombinant proteins and peptides which bind gold through high affinity peptide tags, while retaining their biological activity. Based on this, we have developed Goldbinder technology for application in BioSensor and Biomaterials markets. We have developed sensor applications for surface plasmon resonance and colloidal gold to support commercialization of the technology. We are also establishing proof of principle in animal models for Goldbinder technology to enable Biomaterials with robust surface coatings for imaging and drug delivery.
Bioptigen, Inc.
Durham, NC
Industry Sector: Diagnostics / Eric Buckland
Tel: 919-314-5500
Email:
Bioptigen's pioneering in vivo optical imaging technology allows academic and life science researchers to see pathologies at their earliest stage with unprecedented detail and clarity, across a wide range of subject applications. This sophisticated OCT hardware and software system enables real-time non-invasive imaging of internal tissue microstructure at an unmatched level of precision and depth, and extends the application space to cover a wide range of human and animal subjects. These advances make it possible for researchers to open up new avenues of biological exploration and development, and to foster advances in disease detection and management.
Brown & Herbranson Imaging
Portola Valley, CA
Industry Sector: Clinical Research / Bob Austrian
Tel: 415-794-1199
Email:
eHuman, Inc., and parent company Brown & Herbranson Imaging, are leading providers of 3-D interactive anatomical software applications, services and human datasets for dental, medical and consumer markets. Our core products, already in use within 50% of U.S.-based dental schools, bring the latest volumetric computing, interactive visualization and learning solutions to the spatially complex field of dentistry. Based upon the educational and economic value of our initial products, we are developing the industry’s first Web-based, haptics-enabled surgical simulator and digital curriculum platform, enabling a first-in-class, 21st-century dental pedagogy. Additionally, working with partners including the Stanford School of Medicine, Smithsonian and Max-Planck Institute, our eHuman.com subsidiary is developing the most comprehensive, research-class anatomical imaging, reference and digital learning library for broader health care applications.
Caracal, Inc.
Buffalo Grove, IL
Industry Sector: Healthcare Services / DerShung Yang
Tel: 847-419-9288
Email:
Caracal, Inc. is a premier research and development firm specialized in healthcare-related innovative technology solutions to improve patient outcomes, promote patient self-management, improve access to quality care, and reduce healthcare costs. Our solutions are based on multidisciplinary approaches integrating patient-reported outcomes (PRO) research, e-health and telehealth technologies, evidence-based medicine, and patient education and provider training practice. Our solutions are developed with the collaboration from researchers and practitioners at more than a dozen top-rated research and patient care institutions. We are a main contributor to the endeavors integrating PRO solutions developed at the PROMIS Network, an NIH Roadmap project, into mainstream clinical practice.
Caring Technologies, Inc.
Boise, ID
Industry Sector: Telemedicine / Ron Oberleitner
Tel: 609-306-9181
Email:
Caring Technologies, Inc. delivers a specialty web-based Personal Health Record (PHR) platform which is enhanced by its exclusive worldwide license to a proprietary data capture system called BI Capture™. By delivering these via its popular online autism communication network TalkAutismTM, the Company will revolutionize behavioral medicine treatment and research while providing enriched interaction between individuals with autism and professionals who can be anywhere in the world. Stemming from its traction in the autism category, CT will apply this platform to other pressing health conditions, where the company can leverage this unique hybrid of technology services to facilitate treatment for Alzheimer’s, Parkinson’s, Traumatic Brain Injury, Post Traumatic Stress Disorder, and other costly neurological , neuromuscular and broader chronic illness populations. Ultimately, CT’s technology platform will appeal to the more general health marketplace directly or via sublicense.
CellASIC Corporation
San Leandro, CA
Industry Sector: Instrumentation / Paul Hung
Tel: 510-895-1985
Email:
CellASIC’s long term vision is to develop microfluidic products to foster the next wave of the life science revolution. In the 20th century, it became possible to isolate and study living components (DNA, proteins, cells) in a laboratory setting, giving rise to the modern pharmaceutical industry. The next revolution in human biology will occur when controlled studies can be replicated in the laboratory that are capable of simulating behaviors of entire living system. The basic concept of CellASIC’s technology is to create microfabricated cell culture environments to improve the quality of laboratory experiments.
CFD Research Corporation
Huntsville, AL
Industry Sector: Pharmaceuticals / Shankar Sundaram
Tel: 256-726-4892
Email:
CFD Research Corporation (CFDRC) is the technology leader in advanced engineering solutions (software & hardware, designs and prototypes) for diverse global businesses. CFDRC researches, develops and provides innovative solutions for:
* Aerospace and Defense
* Biomedical and Life Sciences
* Emerging Technologies
Our products and services are used by over 500 organizations worldwide. To accelerate global commercialization of matured simulation technologies, in 2004, CFDRC spun off its software products division. Presently, CFDRC has a highly qualified staff of over 90 employees in Huntsville, AL, and active collaborations with over 30 research organizations worldwide.
In recognition of our commercialization successes, we have been awarded the prestigious Tibbetts Award twice (latest one in 2006) and have been cited in the success stories of NASA, U.S. Navy, Air Force, DARPA, NIH, NSF, and international magazines.
Creatv MicroTech, Inc.
Potomac, MD
Industry Sector: Diagnostics / Cha-Mei Tang
Tel: 301-983-1650
Email:
Creatv MicroTech, Inc. is developing sensitive biodetection platforms. Creatv’s vision is to become a major supplier of diagnostic tests, analytical tools and reagents for the water, food, environmental, pharmaceutical and medical industries. Creatv achieves innovations through both independent and joint research & development with universities and research laboratories. Creatv also performs development in microfabrication. Creatv manufactures advanced x-ray anti-scatter grids and nuclear collimators to improve medical imaging and received R&D 100 Award in 2006 for these products.