This bulletin covers aspects of head and neck cancers and should be of interest to multidisciplinary teams working in this area.

Sections can include:

· Combined Modality Therapies

· Drug Therapy

· Pathology, Staging, Polymorphisms & Biomarkers

· Prognosis, Survival & Risk Factors

· Radiotherapy & Imaging

· Supportive Care & Symptom Management

· Surgery

Many of the following articles are available online via the NHS Scotland Knowledge Network. Please use the links where provided and your ATHENS password. A complete list of available online journals and registration for ATHENS can be found at www.knowledge.scot.nhs.uk/

If the article you require is not available via the NHS Scotland Knowledge Network and you would like to request a print copy, please submit your request online at www.quest.scot.nhs.uk

This bulletin contains a selection of material gathered from a search of the evidence base, and is not intended to be comprehensive. Professional judgment should be exercised when appraising the material. The Library takes no responsibility for the wording, content and accuracy of the information supplied, which has been extracted in good faith from reputable sources. NHSGGC is not responsible for the content of external internet sites.

Compiled by:

Kirsty Coltart

Subject Librarian

Beatson West of Scotland Cancer Centre

0141 301 7285,

General

Chinn SB and Myers JN. (2015). Oral Cavity Carcinoma: Current Management, Controversies, and Future Directions. Journal of Clinical Oncology 33,29:3269-3276.

Dillon MT and Harrington KJ. (2015). Human Papillomavirus-Negative Pharyngeal Cancer. Journal of Clinical Oncology 33,29:3251-3261.

Lee AW, Ma BB, Ng WT, et al. (2015). Management of Nasopharyngeal Carcinoma: Current Practice and Future Perspective. Journal of Clinical Oncology 33,29:3356-3364.

Porceddu SV, Veness MJ and Guminski A. (2015). Nonmelanoma Cutaneous Head and Neck Cancer and Merkel Cell Carcinoma: Current Concepts, Advances, and Controversies. Journal of Clinical Oncology 33,29:3338-3345.

Combined Modality Therapies

Atchariyasathian V, Pruegsanusak K and Wongsriwattanakul S. (2015). Sensorineural hearing loss following induction chemotherapy plus concurrent chemoradiotherapy for advanced nasopharyngeal carcinoma. Journal of Laryngology & Otology 129,8:767-772.

Chen MM, Holsinger FC and Laccourreye O. (2015). Salvage Conservation Laryngeal Surgery After Radiation Therapy Failure. Otolaryngologic clinics of North America 48,4:667-675.

Chen YP, Sun Y, Chen L, et al. (2015). Surrogate endpoints for overall survival in combined chemotherapy and radiotherapy trials in nasopharyngeal carcinoma: Meta-analysis of randomised controlled trials. Radiotherapy & Oncology 116,2:157-166.

Kumar A, Sharma A, Mohanti BK, et al. (2015). A phase 2 randomized study to compare short course palliative radiotherapy with short course concurrent palliative chemotherapy plus radiotherapy in advanced and unresectable head and neck cancer. Radiotherapy & Oncology 117,1:145-151.

Lewis CM, Chronowski GM, Dong W, et al. (2015). Analysis of Charges Associated with Definitive Nonsurgical Therapy for Early-Stage Lateralized Tonsil Cancer. Annals of Surgical Oncology 22,8:2755-2760.

Rodriguez CP, Adelstein DJ, Rybicki LA, et al. (2015). Randomized phase III study of 2 cisplatin-based chemoradiation regimens in locally advanced head and neck squamous cell carcinoma: Impact of changing disease epidemiology on contemporary trial design. Head & neck 37,11:1583-1589.

Russi EG, Moretto F, Rampino M, et al. (2015). Acute skin toxicity management in head and neck cancer patients treated with radiotherapy and chemotherapy or EGFR inhibitors: Literature review and consensus. Critical Reviews in Oncology-Hematology 96,1:167-182.

Theunissen EA, Zuur CL, Jozwiak K, et al. (2015). Prediction of Hearing Loss Due to Cisplatin Chemoradiotherapy. JAMA Otolaryngology-- Head & Neck Surgery 141,9:810-815.

Xu T, Shen C, Zhu G, et al. (2015). Omission of Chemotherapy in Early Stage Nasopharyngeal Carcinoma Treated with IMRT: A Paired Cohort Study. Medicine 94,39:e1457.

Drug & Targeted Therapies

Goyal G, Mehdi SA and Ganti AK. (2015). Salivary Gland Cancers: Biology and Systemic Therapy. Oncology (Williston Park) 29,10:

Lee KW, Koh Y, Kim SB, et al. (2015). A Randomized, Multicenter, Phase II Study of Cetuximab With Docetaxel and Cisplatin as Induction Chemotherapy in Unresectable, Locally Advanced Head and Neck Cancer. Oncologist 20,10:1119-1120.

Zhang LN, Gao YH, Lan XW, et al. (2015). Effect of taxanes-based induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: A large scale propensity-matched study. Oral oncology 51,10:950-956.

Pathology, Staging, Polymorphisms & Biomarkers

Anayannis NV, Schlecht NF and Belbin TJ. (2015). Epigenetic Mechanisms of Human Papillomavirus-Associated Head and Neck Cancer. Archives of Pathology & Laboratory Medicine 139,11:1373-1378.

Cosway B, Paleri V and Wilson J. (2015). Biomarkers predicting chemotherapy response in head and neck squamous cell carcinoma: a review. Journal of Laryngology & Otology 129,11:1046-1052.

Guerra EN, Acevedo AC, Leite AF, et al. (2015). Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis. Oral oncology 51,9:805-818.

Moloney EC, Brunner M, Alexander AJ, et al. (2015). Quantifying fibrosis in head and neck cancer treatment: An overview. Head & neck 37,8:1225-1231.

Pankau T, Wichmann G, Neumuth T, et al. (2015). 3D model-based documentation with the Tumor Therapy Manager (TTM) improves TNM staging of head and neck tumor patients. International Journal of Computer Assisted Radiology & Surgery 10,10:1617-1624.

Teng J, Halbert T, McMurry TL, et al. (2015). Histopathologic margin distance in survival in resection of cutaneous melanoma of the head and neck. Laryngoscope 125,8:1856-1860.

Prognosis, Survival & Risk Factors

Bhatia A and Burtness B. (2015). Human Papillomavirus-Associated Oropharyngeal Cancer: Defining Risk Groups and Clinical Trials. Journal of Clinical Oncology 33,29:3243-3250.

Burris JL, Studts JL, DeRosa AP, et al. (2015). Systematic Review of Tobacco Use after Lung or Head/Neck Cancer Diagnosis: Results and Recommendations for Future Research. Cancer Epidemiology, Biomarkers & Prevention 24,10:1450-1461.

Gourin CG, Starmer HM, Herbert RJ, et al. (2015). Quality of care and short- and long-term outcomes of laryngeal cancer care in the elderly. Laryngoscope 125,10:2323-2329.

Jegadeesh N, Liu Y, Prabhu RS, et al. (2015). Outcomes and prognostic factors in modern era management of major salivary gland cancer. Oral oncology 51,8:770-777.

Lan M, Huang Y, Chen CY, et al. (2015). Prognostic Value of Cervical Nodal Necrosis in Nasopharyngeal Carcinoma: Analysis of 1800 Patients with Positive Cervical Nodal Metastasis at MR Imaging. Radiology 276,2:536-544.

Ryu IS, Roh JL, Cho KJ, et al. (2015). Lymph node density as an independent predictor of cancer-specific mortality in patients with lymph node-positive laryngeal squamous cell carcinoma after laryngectomy. Head & neck 37,9:1319-1325.

Radiotherapy & Imaging

Baulch J, Gandhi M, Sommerville J, et al. (2015). 3T MRI evaluation of large nerve perineural spread of head and neck cancers. Journal of Medical Imaging & Radiation Oncology 59,5:578-585.

Chen YP, Tang LL, Zhang WN, et al. (2015). Prognostic Value and Grading of MRI-Based T Category in Patients With Nasopharyngeal Carcinoma Without Lymph Node Metastasis Undergoing Intensity-Modulated Radiation Therapy. Medicine 94,43:e1624.

Chi FH and Young YH. (2015). Inner ear deficits in irradiated nasopharyngeal carcinoma survivors. Laryngoscope 125,11:2565-2571.

Gregoire V, Langendijk JA and Nuyts S. (2015). Advances in Radiotherapy for Head and Neck Cancer. Journal of Clinical Oncology 33,29:3277-3284.

Hansen CR, Johansen J, Kristensen CA, et al. (2015). Quality assurance of radiation therapy for head and neck cancer patients treated in DAHANCA 10 randomized trial. Acta Oncologica 54,9:1669-1673.

Hemmat SM, Wang SJ, Uzelac A, et al. (2015). The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma. Orl; Journal of Oto-Rhino-Laryngology & its Related Specialties 77,3:132-140.

Jensen AD, Nikoghosyan AV, Lossner K, et al. (2015). COSMIC: A Regimen of Intensity Modulated Radiation Therapy Plus Dose-Escalated, Raster-Scanned Carbon Ion Boost for Malignant Salivary Gland Tumors: Results of the Prospective Phase 2 Trial. International journal of radiation oncology, biology, physics 93,1:37-46.

Kawaguchi Y, Nishiyama K, Hirata T, et al. (2015). Treatment outcomes of external-beam radiotherapy for squamous cell carcinoma of the base of the tongue. International Journal of Clinical Oncology 20,5:891-896.

Kwa SL, Al-Mamgani A, Osman SO, et al. (2015). Inter- and Intrafraction Target Motion in Highly Focused Single Vocal Cord Irradiation of T1a Larynx Cancer Patients. International journal of radiation oncology, biology, physics 93,1:190-195.

Leclerc M, Lartigau E, Lacornerie T, et al. (2015). Primary tumor delineation based on (18)FDG PET for locally advanced head and neck cancer treated by chemo-radiotherapy. Radiotherapy & Oncology 116,1:87-93.

Li C, Sheng S, Men Y, et al. (2015). Emission Computed Tomography for the Diagnosis of Mandibular Invasion by Head and Neck Cancers: A Systematic Review and Meta-Analysis. Journal of Oral & Maxillofacial Surgery 73,9:1875.e1-1875.11.

Lok BH, Chin C, Riaz N, et al. (2015). Irradiation for locoregionally recurrent, never-irradiated oral cavity cancers. Head & neck 37,11:1633-1641.

Owen D, Iqbal F, Pollock BE, et al. (2015). Long-term follow-up of stereotactic radiosurgery for head and neck malignancies. Head & neck 37,11:1557-1562.

Ryu IS, Lee JH, Roh JL, et al. (2015). Clinical implication of computed tomography findings in patients with locally advanced squamous cell carcinoma of the larynx and hypopharynx. European Archives of Oto-Rhino-Laryngology 272,10:2939-2945.

Sheikhbahaei S, Taghipour M, Ahmad R, et al. (2015). Diagnostic Accuracy of Follow-Up FDG PET or PET/CT in Patients With Head and Neck Cancer After Definitive Treatment: A Systematic Review and Meta-Analysis. AJR.American Journal of Roentgenology 205,3:629-639.

Tang LL, Chen L, Mao YP, et al. (2015). Comparison of the treatment outcomes of intensity-modulated radiotherapy and two-dimensional conventional radiotherapy in nasopharyngeal carcinoma patients with parapharyngeal space extension. Radiotherapy & Oncology 116,2:167-173.

van Dijk LK, Boerman OC, Kaanders JH, et al. (2015). PET Imaging in Head and Neck Cancer Patients to Monitor Treatment Response: A Future Role for EGFR-Targeted Imaging. Clinical Cancer Research 21,16:3602-3609.

Varoquaux A, Rager O, Dulguerov P, et al. (2015). Diffusion-weighted and PET/MR Imaging after Radiation Therapy for Malignant Head and Neck Tumors. Radiographics 35,5:1502-1527.

Villari CR and Courey MS. (2015). Management of Dysphonia After Radiation Therapy. Otolaryngologic clinics of North America 48,4:601-609.

Zackrisson B, Kjellen E, Soderstrom K, et al. (2015). Mature results from a Swedish comparison study of conventional versus accelerated radiotherapy in head and neck squamous cell carcinoma - The ARTSCAN trial. Radiotherapy & Oncology 117,1:99-105.

Zhang B, Mo Z, Du W, et al. (2015). Intensity-modulated radiation therapy versus 2D-RT or 3D-CRT for the treatment of nasopharyngeal carcinoma: A systematic review and meta-analysis. Oral oncology 51,11:1041-1046.

Supportive Care & Symptom Management

Best J, Muzaffar J and Mitchell-Innes A. (2015). Quality of information available via the internet for patients with head and neck cancer: are we improving?. European Archives of Oto-Rhino-Laryngology 272,11:3499-3505.

Bonomi M and Batt K. (2015). Supportive Management of Mucositis and Metabolic Derangements in Head and Neck Cancer Patients. Cancers 7,3:1743-1757.

Britton B, McCarter K, Baker A, et al. (2015). Eating As Treatment (EAT) study protocol: a stepped-wedge, randomised controlled trial of a health behaviour change intervention provided by dietitians to improve nutrition in patients with head and neck cancer undergoing radiotherapy. BMJ Open 5,7:e008921.

Brown T, Banks M, Hughes BG, et al. (2015). New radiotherapy techniques do not reduce the need for nutrition intervention in patients with head and neck cancer. European journal of clinical nutrition 69,10:1119-1124.

Cho HK, Jeong YM, Lee HS, et al. (2015). Effects of honey on oral mucositis in patients with head and neck cancer: A meta-analysis. Laryngoscope 125,9:2085-2092.

Cox SR, Theurer JA, Spaulding SJ, et al. (2015). The multidimensional impact of total laryngectomy on women. Journal of communication disorders 56,59-75.

ESMO Clinical Practice Guidelines: Management of oral and gastrointestinal mucosal injury.

(Sep 2015) http://annonc.oxfordjournals.org/content/26/suppl_5/v139.full

Fronczek, A.E. (2015). A Phenomenologic Study of Family Caregivers of Patients With Head and Neck Cancers. Oncology nursing forum 42,6:593-600.

Kanagalingam J, Feliciano R, Hah JH, et al. (2015). Practical use of povidone-iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections. International journal of clinical practice 69,11:1247-1256.

Kaushal P, Atri R, Soni A, et al. (2015). Comparative evaluation of triplet antiemetic schedule versus doublet antiemetic schedule in chemotherapy-induced emesis in head and neck cancer patients. Ecancermedicalscience 9,567.

Kraaijenga SA, Oskam IM, van der Molen L, et al. (2015). Evaluation of long term (10-years+) dysphagia and trismus in patients treated with concurrent chemo-radiotherapy for advanced head and neck cancer. Oral oncology 51,8:787-794.

Kraaijenga SA, van der Molen L, Jacobi I, et al. (2015). Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises. European Archives of Oto-Rhino-Laryngology 272,11:3521-3531.

Lips M, Speyer R, Zumach A, et al. (2015). Supracricoid laryngectomy and dysphagia: A systematic literature review. Laryngoscope 125,9:2143-2156.

Longacre ML, Galloway TJ, Parvanta CF, et al. (2015). Medical Communication-related Informational Need and Resource Preferences Among Family Caregivers for Head and Neck Cancer Patients. Journal of Cancer Education 30,4:786-791.

Murphy BA and Deng J. (2015). Advances in Supportive Care for Late Effects of Head and Neck Cancer. Journal of Clinical Oncology 33,29:3314-3321.

Patterson JM, McColl E, Wilson J, et al. (2015). Head and neck cancer patients' perceptions of swallowing following chemoradiotherapy. Supportive Care in Cancer 23,12:3531-3538.

Rathod S, Livergant J, Klein J, et al. (2015). A systematic review of quality of life in head and neck cancer treated with surgery with or without adjuvant treatment. Oral oncology 51,10:888-900.

Ringash, J. (2015). Survivorship and Quality of Life in Head and Neck Cancer. Journal of Clinical Oncology 33,29:3322-3327.

Sahebjamee M, Mansourian A, Mohammad MH, et al. (2015). Comparative Efficacy of Aloe vera and Benzydamine Mouthwashes on Radiation-induced Oral Mucositis: A Triple-blind, Randomised, Controlled Clinical Trial. Oral Health & Preventive Dentistry 13,4:309-315.

Schindler A, Denaro N, Russi EG, et al. (2015). Dysphagia in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus. Critical Reviews in Oncology-Hematology 96,2:372-384.

Simpson GK, Dall'Armi L, Roydhouse JK, et al. (2015). Does Resilience Mediate Carer Distress After Head and Neck Cancer?. Cancer nursing 38,6:E30-6.

Singer S, Araujo C, Arraras JI, et al. (2015). Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III. Head & neck 37,9:1358-1367.

Whited CW and Dailey SH. (2015). Evaluation of the Dysphonic Patient. Otolaryngologic clinics of North America 48,4:547-564.

Williams WB and O'Ryan F. (2015). Management of Medication-Related Osteonecrosis of the Jaw. Oral & Maxillofacial Surgery Clinics of North America 27,4:517-525.