IUPUI CURRICULUM VITAE FORMAT
FOR PROMOTION AND TENURE DOSSIERS

NAME: MATHER Kieren James

Last / First / Middle

Academic Office:

Indiana University

541 North Clinical Drive, Room CL365

Indianapolis, IN 46202

Clinical Studies Office:

Indiana University Clinical Research Center

550 N University Blvd, Room 5550

Indianapolis, IN 46202

EDUCATION:

POSTDOCTORAL

Institution Degree Date Awarded

See ‘Further Education’ below

GRADUATE

Institution Degree Date Awarded

University of Calgary, Calgary, Alberta, Canada. MD May 1992.

UNDERGRADUATE

Institution Degree Date Awarded

University of Calgary, Calgary, Alberta, Canada. BSc (Biochemistry) with distinction,

June 1989.

FURTHER EDUCATION: (Advanced and Specialty Training, Fellowships, Institutes)

Institution Credential Date Awarded

Indiana University, Indianapolis, Indiana, Postgraduate clinical research fellowship, USA. Dr Alain Baron. 1998 - 1999

University of Calgary, Calgary, Alberta, Canada. Postgraduate clinical research fellowship, Dr Todd Anderson 1996 – 1998

University of Calgary. Calgary, Alberta, Canada Endocrinology Fellowship,

1993 - 1996

University of British Columbia, Vancouver, British Columbia, Canada General Internal Medicine (Core program), 1992 – 1993

The Greater Victoria Hospital Society, Victoria, British Columbia, Canada. (Internship administered by The University of British Columbia, Vancouver, British Columbia, Canada).

Rotating Internship 1991 - 1992

APPOINTMENTS:

ACADEMIC (i.e. academic appointments, including academic administrative roles)

Institution Rank/Title Inclusive Dates

Indiana University School of Medicine Professor of Medicine July 2012-present

Indiana University School of Medicine. Associate Professor July 2007-June 2012 Tenured July 1 2008.

Indiana University School of Medicine, Assistant Professor, Jan 2001 – June 2007.

Indiana School of Medicine, Visiting Assistant Professor July 2000 - Dec 2000.

NON-ACADEMIC (i.e. administrative, hospital or corporate appointments, consultantships)

Institution/Entity Title Inclusive Dates

n/a

LICENSURE, CERTIFICATION, SPECIALTY BOARD STATUS (as applicable for discipline):

Credential Number Inclusive Dates

ABIM (Endocrinology) 1998-2018.

FRCPC (Endocrinology) 1998

FRCPC (Internal Medicine) 1997

ABIM (Internal Medicine) 1996 - 2006.

LMCC (National Licensure Exam Canada) 1994

Indiana State Medical License 01051373 1999 – present

Alberta, Canada. 011789. 1997 –1999.

British Columbia, Canada. 14839. 1993 –1999.

PROFESSIONAL ORGANIZATION MEMBERSHIPS:

Organization Inclusive Dates

Association for Patient Oriented Research 2005 - present

Federation of American Societies for Experimental Biology (FASEB) 2004 – present

American Association for the Advancement Of Science 2002 - present

Central Society for Clinical Research 2002 – present

American Diabetes Association 1997 – present

Canadian Diabetes Association 1996 – present

Canadian Society for Clinical Investigation 1998 – present

The Endocrine Society 1997 – present

British Columbia Internal Medicine Society 1992 – 1999

British Columbia Medical Association 1992 – 1999

Canadian Medical Association 1989 – present

Alberta Medical Association 1989 – present

PROFESSIONAL HONORS AND AWARDS:

TEACHING

Award Name Granted By Date Awarded

Indiana University Trustees Teaching Award 2011

Gold Star for Excellence in Lecturing (Endocrinology), 1999

RESEARCH

Award Name Granted By Date Awarded

Member, American Society of Clinical Investigation, 2012

Order of the Amaranth support for ADA Career Development Award, 2006-2007

Indiana University School of Medicine Outstanding Junior Faculty Research Award, Department of Medicine 2005

American Diabetes Association, Career Development Award 2005-2010

GlaxoSmithKline Endocrinology and Metabolism Scholar Award 2004

American Diabetes Association, Junior Faculty Award 2002-2005

Alberta Heritage Fund for Medical Research, Clinical Fellowship. 1998-2000

SERVICE

Award Name Granted By Date Awarded

OVERALL/OTHER

Award Name Granted By Date Awarded

Nat Christie Foundation Medical Entrance Award for Tuition and Fees. 1989, 1990 and 1991

Joseph Albert Award for Elective Study at Centres of Excellence, 1991

University of Calgary, Faculty of Science Gold Medal, 1989

George I Drummond Memorial Award (Biochemistry), 1989.

National Science and Energy Research Council of Canada summer studentship 1988

Alberta Heritage Foundation for Medical Research summer studentship, 1987 and 1989

Viscount Bennett Scholarship (Undergraduate Merit), 1987.

University of Calgary Undergraduate Merit Award, 1987

PanCanadian Scholarship (Undergraduate Merit), 1985 to 1988

Louise McKinney Post-Secondary Scholarship, 1986, 1988, and 1989

University of Calgary Academic Scholarship for Freshmen, 1985

PROFESSIONAL DEVELOPMENT: List courses, workshops or training programs attended to enhance your performance in any area of academic work.

Course/Workshop Title Provider Date

National Meetings

American Diabetes Association Scientific Sessions 1999 -2012

American Heart Association 1999 - 2004

American Society of Clinical Investigation 2012

The Endocrine Society National Meeting 2000–03, 2011-15

Regional Meetings

Central Society for Clinical Research 2001 - 2015

Faculty Development Programs

Grant writing seminar IUPUI 2004, 2010

LIBRARIAN PERFORMANCE:

n/a

TEACHING:

TEACHING ASSIGNMENTS: List the course number, brief title, format (i.e. lecture, lab, clinic, online); your role (course director, lecturer), year and term, enrollment and other information that specifically pertains to your discipline (i.e. contact hours, hours of lab instruction, time instructing students on wards or clinics, course-related advising.) Mean teaching evaluation scores may be included.

UNDERGRADUATE

Course # Short Title Format Role Term Enrollment

GRADUATE

Course # Short Title Format Role Term Enrollment

Introduction to Clinical Medicine II (2nd year core curriculum). Endocrinology component. Team teaching of core endocrinology, 2X1 hour presentations per year.

G805 Diabetes and Obesity – One-hour lecture per course year 2004, 2005,2010. Graduate level team-taught course for physiology, endocrinology and metabolism PhD students

93MI710 Scientific Basis of Clinical Therapeutics – 2 hours small group teaching per course year 2003-present. Clinical diabetes case studies.

POSTGRADUATE

Course # Short Title Format Role Term Enrollment

Clinics and Clinical Teaching:

Wishard Hospital General Endocrinology Clinic (16 hours/mo)

Indiana Clinic Outpatient General Endocrinology (16 hours/mo)

Inpatient consultation service attending 3 months/year (includes teaching rounds 5 days per week and bi-weekly case-based workshops; teaching average 1 fellow, 2 residents and 1 medical student)

CONTINUING EDUCATION

Course # Short Title Format Role Term Enrollment

MENTORING: List mentoring activities that pertain to your discipline such as thesis or advisory committees, students on research rotations, postdoctoral fellows and visiting scholars, advisor to graduating students, mentor for peer and self-assessment review, faculty mentoring committees. Name the individual, identify your role and provide inclusive dates.

Individual Role Inclusive Dates

PhD Committees:

Abbas Conteh; MD/PhD program, Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr J Tune). Hemodynamic and molecular differences in the cardioprotective response to GLP-1 agonism in lean and obese Ossabaw swine.

Graduate Committee Member 2014 - 2016

Daniel Sassoon, BS; MD/PhD program, Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr J Tune). MicroRNA changes in response to GLP-1 agonism modify the response to ischemia in lean and obese Ossabaw swine.

Graduate Committee Member 2014 - 2016

Stacey Dineen, BS; PhD program, Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr M Sturek). Effects of the GLP-1 agonist, exenatide, on the sarco/endoplasmic reticulum calcium ATPase (SERCA) and ER stress in coronary smooth muscle cells. Graduate Committee Member 2013 - 2015

Saurabh Thosar, BS, PhD Program. Indiana University Department of Kinesiology (Faculty supervisor Dr J Wallace). Effects of Sedentary Time on Vascular Function

Graduate Committee Member 2012-2014

Chawla, Aarti BSc, PhD program. Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr M Sturek). Effects of AICAR on myocardial metabolism and ischemia tolerance in Ossabaw swine with and without PKARg3 mutations.

Graduate Committee Member 2011-2012

Steve Moberly BSc, MD/PhD program. Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr J Tune). Effects of GLP-1 on metabolism in ischemic and reperfused myocardium. Co-Mentor, MD/PhD program 2010 - 2012

Zachary Berwick, BSc. Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr J Tune). Molecular determinants of hemodynamic response to ischemia

Graduate Committee Member 2010-2012

Blair Johnson, MS. Indiana University Department of Kinesiology (Faculty supervisor Dr J Wallace). Effects of Resistance Exercise on Vascular Function

Graduate Committee Member 2009-2011

Jaume Padilla MS. Indiana University Department of Kinesiology (Faculty supervisor Dr J Wallace). Nitrergic mechanisms underlying the vasodilator response to forearm ischemia.

Graduate Committee Member 2008-2010

Ryan Harris MS. Indiana University Department of Kinesiology (Faculty supervisor Dr J Wallace). Exercise modulation of fat-induced vascular dysfunction.

Graduate Committee Member 2007-2009

Reina Watanabe MS. Indiana University Department of Cellular and Integrative Physiology (Faculty supervisor Dr J Tune). Potassium channel regulation of coronary microvasculature in a pig model of insulin resistance. Exploratory translational project for measuring coronary potassium channel activity in human obesity (Institutional Award)

Graduate Committee Member 2007-2009

Clinical research teaching:

Farah Meah (Fellow) – 60 hours 2014 - present

Marisa Fisher (Fellow) – 200 hours 2013 - present

Maysa Hussain (Resident) – 90 hours 2012 - present

Jun Chung (MS4) – 95 hours Feb 2011 – August 2011

Yash Patel (resident) – 520 hours Oct 2009 – 2011.

MPH research projects. Seasonality and endothelium-dependent vasodilation, analyses of a diabetes prevention clinical trial dataset for planned secondary outcomes.

Pooja Singal (fellow) – 200 hours Sep 2006 – 2010

Resident research project. User-independent approach to measuring insulin sensitivity with hyperinsulinemic euglycemic clamps.

Nancy Yoon (fellow) – 80 hours March 2006 – June 2008

Medicine resident research project. Blood pressure response to systemic endothelin antagonism in lean, obese, and diabetic subjects.

Emily Veeneman (fellow) – 150 hours September 2004 – June 2007

Fellowship clinical research project – PET studies of myocardial blood flow regulation in lean and obese subjects.

Prashant Vaishnayva – 400 hours Sep – Nov 2004

Visiting medical student, lab-based project contributing to plasma analyses for studies of the effect of endothelin on skeletal muscle insulin resistance in obese humans.

Inessa Gelfand (fellow) – 150 hours December 2003 – present

Fellowship clinical research project investigating the application of repaglinide to the clinical care of patients with cystic fibrosis-related diabetes mellitus.

Lori Brame (fellow) – 200 hours April 2003 – June 2004

Training in all aspects of clinical research including study design, procedures, data collection and assessment, statistical analysis and presentation of results in oral and written formats.

Amale Lteif (fellow) - >1000 hours Aug 2001-June 2003

Training in all aspects of clinical research, including bedside procedures, data collection and data assessment, statistical analysis, and presentation of results in both oral and written form.

Bahram Mirzamohammadi (fellow)- 40 hours July 2000 – Jan 2001

Training in all aspects of clinical research, including bedside procedures, data collection and data assessment, statistical analysis, and presentation of results in both oral and written form.

TEACHING ADMINISTRATION AND CURRICULUM DEVELOPMENT:

n/a

GRANTS/FELLOWSHIPS IN TEACHING:

n/a

INVITED PRESENTATIONS – TEACHING

n/a

RESEARCH/CREATIVE ACTIVITY:

GRANTS/FELLOWSHIPS IN RESEARCH: Organize grants to differentiate active from pending/under review. Include your history of past grant support. If a record of effort to obtain funding is expected in your discipline and/or rank, include proposal submitted but not funded.

ACTIVE RESEARCH GRANTS/FELLOWSHIPS

Title Granting Agency Role % Effort Amount Dates

COMPLETED RESEARCH GRANTS/FELLOWSHIPS

Title Granting Agency Role % Effort Amount Dates

PENDING RESEARCH GRANTS AND FELLOWSHIPS

Title Granting Agency Role % Effort Amount Dates

SUBMITTED BUT NOT FUNDED RESEARCH GRANTS/FELLOWSHIPS

Title Granting Agency Role % Effort Amount Dates

INVITED PRESENTATIONS – RESEARCH

LOCAL

Title Organization Date

Role of Endothelin in Insulin Action American Diabetes Association 2003

Hormonal control of vascular function Endocrinology Division Grand Rounds 2005

Approaches to measuring in vivo metabolism

Endocrinology Division Grand Rounds 2008

GLP-1 and Myocardial Fuel Selection Endocrinology Division Grand Rounds 2011

Diabetes treatments and heart disease Cardiology Division Grand Rounds 2012

REGIONAL

Title Organization Date

NATIONAL

Title Organization Date

Vascular Function and Cardiovascular Risk in Diabetes Mellitus. Clinical Update, May 2000, University of Calgary Continuing Medical Education.

Insulin resistance, endothelin, and vascular dysfunction in obesity and diabetes. Grand Rounds, University of Oklahoma, Oklahoma City OK. May 2005.

Endothelin in vascular and metabolic dysfunction in insulin resistance. Cardiology grand rounds, University of Kentucky, Knoxville KY. February 2007.

Renal Disease and the Metabolic Syndrome American Society of Nephrology 2007 Annual Meeting. November 2007

The Endocrine Society Diabetes Diagnosis and Management Day, 2011-14. Co-Director.

Cardiovascular Benefits of GLP-1: Fact or Fantasy. Physiology Seminar, University of Mississippi, Sept 2014

INTERNATIONAL

Title Organization Date

Endothelial Function in the Polycystic Ovary Syndrome. 1st Virtual Congress of Endocrinology, Brazil. January 2001. http://www.endocrinologia.org.br

Insulin Resistance, Metabolic Syndrome and Vascular Diseases: Update on Mechanistic Linkages. Canadian Vascular Biology Working Group, Vancouver. Aug 2003.

Role of Insulin in Vascular Health. Korean Diabetes Society 2007 Annual Meeting. Pusan, Korea. November 2007

GLP-1 based treatments for diabetes. Mexican Internal Medicine society 2010 Annual Meeting August 2010.

SERVICE:

Distinguish between service to the University and service to your professional discipline. If a service activity spans academic levels (i.e. Department, School, Campus, University) list it once. Identify your role in leadership (i.e. member, co-chair, chair).

UNIVERSITY SERVICE:

DEPARTMENT

Activity Role Inclusive Dates

IU School of Medicine Promotion and Tenure Committee 2014 - present

SCHOOL

Activity Role Inclusive Dates

IU-CTSI Clinical Research Committee Oversight Committee 2008 - present

CAMPUS

Activity Role Inclusive Dates

IUPUI Institutional Review Board Member 2005-2012

UNIVERSITY

Activity Role Inclusive Dates

IUPUI Research Support Fund Grant reviewer 2006 – 2012

IU-CTSI Preclinical Development Team Project review 2009 - 2012

IU-CTSI Concepts to Clinic Project Development Team 2013 – present

IU-CTSI Peer Review and Mentoring Committee – Obesity and Metabolic Diseases 2014-present

PROFESSIONAL SERVICE:

LOCAL

Organization Activity Inclusive Dates

REGIONAL

Organization Activity Inclusive Dates

Midwest Branch of the American Federation for Medical Research, Board Member, 2005 - 2007.

Midwest Branch of the American Federation for Medical Research, Treasurer, 2008 - 2011.

Midwest Branch of the American Federation for Medical Research, President Elect 2011-2012

Midwest Branch of the American Federation for Medical Research, President 2012 - 2013

NATIONAL

Organization Activity Inclusive Dates

American Federation for Medical Research, Council Member, 2002-present.