BUDGET JUSTIFICATION
A. SENIOR/KEY PERSON(S)
Philip S. Green, Ph.D., Principal Investigator (2 AY months and 2 summer months: Years 1-5)
Dr. Green is an Assistant Professor of Kinesiology, the Director of the Muscle Biology Laboratory and a faculty member in the Center for Personalized Health Monitoring at the University of Massachusetts-Amherst. Dr. Green …
Jane A. Turner, Ph.D., Co-Investigator (1 AY month and 1 summer month: Years 1-5)
Dr. Turner is a Professor of Kinesiology, Director of the Muscle Physiology Laboratory and faculty member in the Center for Personalized Health Monitoring at the University of Massachusetts-Amherst. She will …
Jack Ho, Ph.D., Statistician (0.30 calendar months: Years 1-5)
Dr. Ho is a Professor of Mathematics and Statistics and faculty member in the Center for Personalized Health Monitoring at the University of Massachusetts-Amherst. He will …
B. OTHER PERSONNEL
Phyllis Stockholm, Ph.D., Postdoctoral Fellow (12 calendar months: Years 1-5)
Dr. Straight is a postdoctoral fellow in Dr. Green’s laboratory, where he has focused on single fiber experiments since his arrival in August of 2015. He will be responsible for…
TBD, Project Coordinator/Exercise Trainer (12 calendar months: Years 1-5)
This individual will be a Master’s level assistant who will work closely with the PI to ensure the smooth running of day-to-day operations of the overall project. The Project Coordinator will be responsible for all …
TBD, Laboratory Technician (12 calendar months: Years 1-5)
This person will be responsible for a large number of the single fiber mechanical and biochemical assessments. Specifically, the technician will …
Graduate Research Assistant (RA), Kinesiology (6 months (20 hours per week, 52 weeks) Years 1-5)
The primary responsibilities of the graduate RA will be to assist Dr. Turner and the PI with …
Fringe Benefits
· The regular fringe benefit rate is 37.34% (35.68% Workers Compensation, Group Insurance and Retirement, UI, UHI, MTX; plus Health & Welfare of $16.50/week.) Non-faculty positions also include Sick Leave Bank of 0.66%.
· Faculty Summer Salary fringe benefit rate is 2.18%, which includes workers compensation, UI, UHI, MTX.
· Post-doctoral fellow fringe is 15.26% (14.26% Workers Compensation, Group Insurance and Retirement, UI, UHI, MTX; plus Health & Welfare of $15.00/week.)
· Graduate Student fringe includes Health and Welfare of $16.50/wk. assessed to all Graduate Student appointments, a GEO Health Deferment Rate of 18.66% on academic and summer wages, and 2.18% for UI, UHI, MTX in the summer.
All personnel costs include an annual 2% cost of living raise.
C. EQUIPMENT None
D. Travel
Conference Travel ($12,500 total)
Funds in the amount of $2,500 per year for each of the 5 years are requested for travel by the PI and co-investigators to appropriate domestic conferences to disseminate the results from this research.
E. PARTICIPANT /TRAINEE SUPPORT COSTS None
F. OTHER DIRECT COSTS
F.1 Materials and Supplies ($111,230 total)
Activity Monitoring, Minor Equipment And Software ($4,070 total, Year 1)
Funds for the purchase of …
Software ($1,930 total)
Funds to purchase a Matlab license …
Computer ($1,800 total)
Funds are requested to purchase 1 laptop computer, docking station and monitor in Year 1. This laptop will be 100% dedicated to this project for the project coordinator to manage all recruiting activities; maintain study and IRB records; analyze portions of the data; compile all data for each Aim; conduct the statistical analyses; and archive all analysis programs, presentations and publications generated throughout the project.
Consumable Lab Supplies for Single Fiber Studies ($100,000 total)
We have estimated our costs based on the expenditures in Dr. Green’s laboratory for recent projects (AG-031303) that employed similar analytical approaches. We estimate the need for $20,000 per year for chemicals, reagents, gels and consumable supplies related to Aims 1-2. This includes …
Other Lab Supplies ($7,500 total)
Funds are requested ($1,500 per year) for Drs. Green’s and Turner’s lab/office supplies to support the studies planned in Aim 1 and 2. These supplies include tape, velcro, data storage materials, cleaning supplies, cables, small repairs, toner, paper, etc.
F.2. Publication Costs ($7,500 total)
Funds in the amount of $1,500 per year are requested to help defray publication costs for the manuscripts stemming from this work.
F.3. Consultant Costs None
F.4. ADP/Computer Services None
F.5. Subawards/Consortium/Contractual Costs ($203,304 total) $38,509 year 1; $39,621 year 2; $40,698 year 3; $41,715 year 4; $42,761 year 5
Dr. Michael Sussman, Co-Investigator, is an Associate Professor in the Department of Medicine at the University of Minnesota. Dr. Sussman will …
F.6. Equipment or Facility Rental/User Fees ($67,750)
Funds are requested for facility fees for the studies planned in Aim 1, which will be performed in the Human Magnetic Resonance Center (2nd floor, Life Science Laboratory), Center for Personalized Health Monitoring (3rd floor, Life Science Laboratory) and the Body Shop Fitness Center (1st floor, Totman Building).
Human Magnetic Resonance (MR) Center, Facility Fees ($55,000 total)
We are requesting $11,000 per year, for the magnetic resonance imaging planned for Aim 1 (one hour per visit x $550 per hour x 20 participants). This is the University of Massachusetts-Amherst internal rate for our Siemens Skyra 3T scanner.
Center for Personalized Health Monitoring, Facility Fees ($9,500 total)
Funds are requested for the skeletal muscle biopsies, whole muscle contractile function measures and dual energy x-ray absorptiometry (DEXA) planned for Aim 1. Over the 5 years of the study, biopsies will require $5,000 ($50 per visit x 50 participants x 2 visits), contractile function will require $1,500 ($15 per visit x 50 participants x 2 visits) and DEXA will require $3,000 ($30 per visit x 50 participants x 2 visits) for facility fees. For planning purposes, these services are distributed evenly over the 5 years, for a cost of $1,900 per year.
Body Shop Fitness Center, Facility Fees ($3,250 total)
We are requesting $3,250 total or $650 per year in facility fees for access to the appropriate exercise equipment for this study ($65 per participant x 50 participants).
F.7. Alterations and Renovations None
F.8. Human Subject Compensation
We are requesting $11,000 per year for 50 study participants to receive three payments (one at each phase of the study). Payments are as follows: phase I completion $20; phase II completion $100; phase III completion $100.
Yes, G. is omitted !
H. Indirects
Indirect costs at the federally-negotiated rate of 59.5% have been included.
Created: 4 January 2017