2006 San Diego, CA
2004 – Baltimore ImToxSS Member in Bold
Functional Flow Cytometry - CE
Chair: Leigh Ann Burn Naas and Nancy Kerkvliet
Speakers:
C. Bortner – Introduction to Flow Cytometry
Debbie Laskin – Assessment of Macrophage-Induced Tissue Injury in Liver/Lung by Flow Cytometry
Nancy Kerkvliet – In Vivo Assessment of T-Cell Activation Using Flow Cytometry
Scott Burchiel – Flow Cytometric Approaches to Understanding Mechanisms of Toxicant Action
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Skin Sensitization and Allergic Contact Dermatitis - CE
Chair: Frank Gerberick and Ian Kimber
Speakers:
Ian Kimber – The Basic Biology and Immunology of Skin Sensitization and Allergic Contact Dermatitis
David Basketter – Skin Sensitization: Predictive Tests and Hazard Identification
Frank Gerberick – Relative Potency, Exposure, and Risk Assessment
Denise Sailstad – The Global Regulatory Environment
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Systemic Drug Allergy: Frequency, Challenges, Mechanisms, and Need for Predictive Models - Workshop
Chair: Ray Pieters and Jack Dean
Speakers:
Jack Dean and Ray Pieters – Systemic Drug Allergy: Frequency, Challenges, mechanisms, and Need for Predictive Models
Jack Uetrecht – Mechanisms of Adverse Effects of Low Molecular Weight Chemicals
Ray Pieters – Popliteal Lymph Node Assay and Recent Mechanistic Studies
Jean Meade and Jim Weaver – Modification of the Local Lymph Node Assay to Evaluate the Potential for Adverse Immunologically-Mediated Drug Reactions
Brad Gutting – The Use of the PLNA in Relation to Oral Route of Exposure to LMWCS
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Histomorphology and Beyond: Correlating Non-Clinical Immune Modulation with Clinical Data - Workshop
Chair: Lynda Reid and JoAnn Schuh
Speakers:
JoAnn Schuh and Lynda Reid – Histomorphology and Beyond: Correlating Non-Clinical Immune Modulation with Clinical Data
C. Kuper – Immunotoxicology and the Mucosal Immune System
Jeff Vos – Protocols and Validation Studies of Histopathology and Immune Function in Non-Clinical Studies
D. Mellon – Regulatory Implications of Non-Clinical Immunotoxicological Findings During the Drug Development Process in the United States
Mike Holsapple et al. – Concordance of Animal Toxicity and Safety Pharmacology Data with Human Toxicities for Therapeutic Agents: Focus on the Immune System
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Gene Expression Influences on Metal Immunomodulation – Symposium
Chair: David Lawrence and Mike Lynes
Speakers:
David Lawrence – Gene Expression Influences on Metal Immunomodulation
Mike Lynes, Kevin Crowthers, et al. – Influence of Metallothionein Gene Expression on Stress-Mediated Immunomodulation
A. Fontenot – MHC Genetics and Sensitivity to Beryllium
David Lawrence and Yong Heo – Cytokine Gene Expression Modified by Lead
Allen Rosenspire – Modulation of Protein Interactions by Mercury: Molecular Analysis of Signaling Pathways to Uncover Mechanisms of Hg Immunotoxicity
Michael Pollard – Genetic Checkpoints in Heavy Metal-Induced Systemic Autoimmunity
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Modulation of Host Defenses by Ambient and Source Particulate Air Pollutants – Symposium
Chair: Ian Gilmour and Matt Reed
Speakers:
Matt Reed and Ian Gilmour – Modulation of Host Defenses by Air Pollutants
Ian Gilmour and MaryJane Selgrade – Mechanisms of Host Defense
A. Pope – Epidemiology of Ambient Air Pollution and Pulmonary Infection
Kevin Harrod et al. – Increased Lung Pathogenesis to Respiratory Viral Infection by Diesel Engine Combustion Components
J. Antonini – Effect of Workplace Particulates on the Susceptibility to Bacterial Infection and the Suppression of Lung Defense Responses in Rats
Judy Zelikoff, Mitch Cohen, et al.– Exacerbation of Pulmonary Pneumonia by Inhaled Ambient Particulate Matter and Associated Metals
S. Kleeberger – Role of Toll-Like Receptors (TLRs) in Responses to Air Pollutants and Infections
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Environmental Pollution and the Immune System: Mechanisms of Immunotoxicity - Symposium
Chair: Dori Germolec and Bob Luebke
Speakers:
Bob Luebke and Dori Germolec – Environmental Pollution and the Immune System: Mechanism of Immunotoxicity Across Phyla
K. Davis and R. Mulpuri – Disease Resistance and Innate Immunity in Plants
A. Goven and L. Fitzpatrick – Chemical Toxicity and host Defense in Invertebrates: An Earthworm Model for Immunotoxicology
L. Rollins-Smith – Environmental Chemicals and Amphibian Immunity: What Are the Risks to Amphibian Health?
Charlie Rice – Fish as Experimental Models in Immunotoxicology: Evolutionary Mechanisms of Action