Supplementary Table 1. Umbilical cord-blood proteins analyzed with IPA.
Symbol, identification number, name, localization, as well as protein classification, role and tentative physiological function are reported.
N. / Symbol / Uniprot/
Swissprot
ID / Name / Function / Ref.
ABCA1 / O95477 / ATP-binding cassette, sub-family C, member 1 / Other (transporter) / 4
ABCA2 / Q9BZC7 / ATP-binding cassette, sub-family A, member 2 / Other (transporter, metabolism, neural development) / 4
ABCA4 / P78363 / ATP-binding cassette, sub-family C, member 4 / Other (transporter) / 4
ABCD1 / P33897 / adrenoleukodystrophy protein / Other (transporter) / 4
ABHD7 / Q8IUS5 / abhydrolase domain containing 7 / Enzyme / 1
ACADS / P16219 / Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain / Enzyme / 1
ACRC / Q96QF7 / Acidic repeat-containing protein / Uknown / 4
ACTA1 / P02568 / Alpha actin / Structural / 3, 4
ACTB / P60709 / beta actin / Structural / 1, 4
ACTG1 / P63261 / Actin, gamma 1 propeptide cytoskeletal / Structural / 1, 2, 4
ACTN2 / P35609 / Alpha actinin 4 / Structural / 4
ACTN4 / O43707 / Alpha actinin 4 / Structural / 1
ADA / P00813 / Adenosine deaminase / Immune system (T-cell activator) / 1, 2
AHNAK / Q09666 / Desmoyokin (Neuroblast differentiation-associated protein) / Transcriptional control (neural cell differentiation) / 4
AK1A1 / P14550 / Alcohol dehydrogenase [NADP1] (Aldehyde reductase) / Enzyme – Metabolism / 1
ALB / P02768 / Serum albumin (precursor) / Other (regulation of the colloidal osmotic pressure of blood) / 4
ALDH18A1 / P54886 / Delta-1-pyrroline-5-carboxylate synthetase (P5CS) / Enzyme – Metabolism / 1
ALDOA / P04075 / Aldolase A, fructose-bisphosphate aldolase / Enzyme – Metaoblism / 1
AML1 / Q01196 / Runt-related transcription factor 1 / Transcriptional control / 4
ANKRD26 / Q9UPS8 / Ankyrin repeat domain-containing protein 26 (KIAA1074) / DNA damage repairing / 1
ANXA11 / P50995 / Annexin 11 / Cell cycle regulation / 3
ANXA2 / P07355 / Annexin 2 / Oxidative stress (heat stress response – calcium binding) / 1
ANXA5 / P08758 / Annexin 5 / Enzyme – Clotting cascade / 1
APOB / P04114 / Apo B-100 / Other (chylomicrons transport) / 4
APOC3 / P02656 / apolipoprotein C-III / Other (delays catabolism of triglyceride-rich particles) / 1
APOF / Q13790 / apolipoprotein F / Other (cholesterol transport) / 2
APP / P05067 / Amyloid precursor protein 639 / Growth regulation (neural) / 1
APRT / P07741 / Adenine phosphoribosyltransferase / Enzyme / 1
ARHGAP17 / Q68EM7 / Rho GTPase-activating protein 17 (Nadrin) / Other (apical polarity of epithelial cells) / 1
ARHGDIB / P52566 / Rho GDP-dissociation inhibitor 2 / Transport / 1
ARID1A / O14497 / BRG1-Associated Factor 250a / Transcriptional control / 4
ARPC4 / P59998 / Actin related protein 2/3 complex subunit 4 / Structural / 1
ARPC5 / O15511 / Actin related protein 2/3 complex subunit 5 / Structural / 1
ASTN1 / O14525 / Astrotactin 1 / Other (post-mitotic migration of young neurons) / 4
ATIC / P31939 / 5-aminoimidazole-4-carboxamide ribonucleotide / Enzyme (purine biosynthesis) / 1
ATM / Q13315 / Serine-protein kinase ATM / DNA damage repairing / 4
ATP2B1 / P20020 / Plasma membrane calcium ATPase isoform 1 / Other (calcium transport) / 4
ATP2B4 / P23634 / Plasma membrane calcium-transporting ATPase 4 / Other (calcium transport) / 4
ATP2C2 / O75185 / Probable calcium-transporting ATPase KIAA0703 / Other (calcium transport) / 4
ATP6 / Q9B1D3 / ATP synthase, H1 transporting, mitochondrial / Transport / 1
Ba1-651 / Q7TP27 / similar to Ba1-651 / Enzyme – Oxidoreductase / 1
BAI1 / O14514 / Brain-specific angiogenesis inhibitor 1 / Other (engulfment of apoptotic cells, anti-angiogenetic signaling in the brain) / 4
BANF1 / O75531 / Barrier-to-autointegration factor / Transcriptional control / 1
BLM / P54132 / Bloom syndrome protein / DNA damage repairing / 4
BRCA2 / P51587 / Breast cancer type 2 susceptibility protein / DNA damage repairing / 4
BRD2 / P25440 / Bromodomain containing protein 2 / Transcriptional control / 4
BSN / Q9UPA5 / Bassoon; zinc finger protein 231; neuronal double zinc finger protein / Other (neurotransmitter release) / 4
C1orf212 / Q96EX1 / Hypothetical protein BC011880 / Uknown / 1
C1QBP / Q07021 / Complement component 1 q subcomponent binding protein / Uknown (binds to C1q) / 1
CA5A / P35218 / carbonic anhydrase VA, mitochondrial / Enzyme / 1
CABIN1 / Q9Y6J0 / Calcineurin-binding protein 1 / Cell cycle regulation (Chromatin assembly) / 4
CACNA1A / O00555 / alpha1A-voltage-dependent calcium channel / Other (channel) / 4
CALD1 / Q05682 / caldesmon 1 isoform 4 / Structural / 1
CALR / P27797 / calreticulin / Protein folding / 1
CAP1 / Q01518 / Adenylyl cyclase-associated protein 1 / Translational control (mRNA localization for cell polarity) / 3
CAPZA1 / P52907 / F-actin capping protein alpha-1 subunit (CapZ alpha-1) / Structural / 1, 3
CBX3 / Q13185 / Chromobox homolog 3 / Transcriptional control / 1
CCNI / Q14094 / Cyclin I / Cell cycle regulation (Spermatogenesis) / 1
CCT2 / P78371 / Chaperonin containing TCP1, subunit 2 / Protein folding / 2
CCT5 / P48643 / Chaperonin containing TCP1, subunit 5 / Protein folding / 2
CCT6A / Q59ET3 / Chaperonin containing TCP1, subunit 6A (zeta 1) / Protein folding / 1
CCT7 / Q53HV2 / Chaperonin containing TCP1, subunit 7 (eta) / Protein folding / 1
CD3D / P04234 / T cell receptor CD3 delta / Immune system / 1
CD52 / P31358 / CDW52 antigen (CAMPATH-1 antigen) / Transport (carbohydrate) / 1
CDKN3 / Q16667 / Cyclin-dependent kinase associated protein phosphatase / Cell cycle regulation / 1
CEP290 / O15078 / CTCL tumor antigen se2-2 (KIAA0373 protein) / Transcriptional control / 2
CEP350 / Q5VT06 / Centrosome-associated protein 350 / Cell cycle regulation (centriol growth) / 4
CER1 / O95813 / protein related to DAN and cerberus / Other (cytokine) / 1
CFL1 / P23528 / Cofilin, non muscle isoforms / Structural / 3
CHAF1A / Q13111 / chromatin assembly factor/CAF-1 p48 subunit; MSI1 protein homolog / Transcriptional control / 1
CHRAC1 / Q9NRG0 / chromatin accessibility complex 1 / Transcriptional control / 1
CLCA1 / A8K7I4 / Calcium-activated chloride channel protein 1 / Other (channel) / 4
CLIC1 / O00299 / Chloride intracellular channel 1, p64CLCP / Transport (channel) / 1, 3
CLTC / Q00610 / Clathrin heavy chain / Transport / 1
CMAS / Q8NFW8 / N-acetylneuraminic acid synthase / Enzyme – Metabolism / 2
CMTM4 / Q8IZR5 / chemokine-like factor super family 5, transcript variant 4 / Other (chemotaxis) / 1
CNTN2 / Q02246 / Contactin 2, precursor / Other (axon growth and guidance) / 1
COL10A1 / Q03692 / type X alpha 1 collagen / Structural / 1
COL4A1 / P02462 / Arresten (Collagen alpha-1(IV) chain) / Structural / 1
COP9 / Q53QS9 / COP9 homolog / Uknown / 1
CORO1A / P31146 / Coronin, actin binding protein 1 alpha / Structural (defense response) / 1
COX6B1 / P14854 / Cytochrome c oxidase subunit Vib / Metabolism / 1
CPSF2 / Q9P2I0 / Cleavage and polyadenylation specific factor 2 / Transcriptional control; Translational control / 1
CRKL / P46109 / Crk-like protein / Other (signal transduction) / 1
CRYGD / P07320 / Crystallin, gamma D / Structural (eye lens) / 1
CSPG2 (VCAN) / P13611 / Chondroitin sulfate proteoglycan 2 (versican) / Cell cycle regulation; Differentiation / 4
CSPG4 / Q6UVK1 / melanoma-associated chondroitin sulfate proteoglycan-like (MCSP), Chondroitin sulfate proteoglycan 4 / Cell cycle regulation; Differentiation / 1
CST6 / Q15828 / Cystatin M / Defense response / 1
CTNNA1 / P35221 / Alpha catenin / Cell differentiation / 4
CUTA / O60888 / acetylcholinesterase putative membrane anchor (brain) / Other / 1
CXCL11 / O14625 / small inducible cytokine B11 (precursor) / Immune system (defense response) / 1
DAXX / Q9UER7 / ETS1-associated protein EAP1/Daxx / Transcription control (apoptosis) / 4
DDAH1 / O94760 / NG,NG-dimethylarginine dimethylaminohydrolase 2 / Oxidative stress -. Enzyme / 1
DDX21 / Q9NR30 / RNA helicase II/Gu protein / Translational control / 1
DDX3Y / O15523 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked / Transcriptional control (spermatogenesis) / 1
DENND4A / Q7Z401 / C-myc promoter-binding protein / Cell cycle regulation / 4
DES / P17661 / Desmin / Structural / 4
DHCS1 / Q96JQ0 / Protocadherin 16 / Other (calcium dependent cell adhesion molecule) / 4
DHX40 / Q8IX18 / DEAH (Asp-Glu-Ala-His) box polypeptide 40 / Other (RNA helicase) / 1
DKFZP566K023 / *NP_056300 / DKFZP566K023 / Uknown / 2
DLST / P36957 / Dihydrolipoamide S-succinyltransferase / Enzyme / 1
DMD / P11532 / Dystrophin / Structural / 4
DNMT3B / Q9UBC3 / cytosine-5 methyltransferase 3 beta isoform 2 / Transcriptional control (de novo methylation of DNA) / 1
DNPEP / Q9ULA0 / Aspartyl aminopeptidase / Metabolism (protein and peptide) / 1
DSCAMSL1 / Q8TD84 / Down syndrome cell adhesion molecule / Other (nervous system development – cell adhesion molecule) / 4
DSP / P15924 / Desmoplakin / Structural / 1, 4
DYSF / O75923 / Dysferlin 1 / Stress response (calcium binding) / 1
ECH1 / Q13011 / d,3,5-d,2,4-Dienoyl-CoA isomerase, mitochondrial / Enzyme – Metabolism (fatty acid) / 3
ECHS1 / P30084 / Mitochondrial short-chain enoyl-coenzyme A hydratase 1 / Enzyme / 1
EEF1A1 / P68104 / Eukaryotic translation elongation factor / Protein biosynthesis / 1
EEF1B2 / P24534 / Elongation factor 1-beta (EF-1-beta) / Translational control / 1
EEF1D / P29692 / eukaryotic translation elongation factor 1 delta isoform 2 / Translational control / 1
EIF1 / P41567 / Eukaryotic translation initiation factor 1 (SUI1) / Translational control / 1
EIF2A / Q9BY44 / translation initiation factor IF-2 homolog / Translational control / 2
EIF3A1 / Q14152 / eukaryotic translation initiation factor 3, subunit 1 alpha / Translational control / 1
EIF3B2 / P55884 / eukaryotic translation initiation factor 3, subunit 2 beta / Translational control / 1
EIF3I / Q13347 / TGF-b receptor interacting protein 1 / Translational control / 3
EIF3S2 / Q13347 / Eukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa / Translational control / 1
EIF5A1 / P63241 / Eukaryotic translation initiation factor 5A / Translational control / 1
EIF5B / O60841 / Eukaryotic translation initiation factor 5B / Translational control / 4
ENO1 / P06733 / Alpha Enolase / Enzyme- Metabolism / 1, 2, 3
ENO3 / P13929 / Beta enolase / Enzyme – Metabolism / 1
ETFA / P13804 / Electron transfer flavoprotein, alpha polypeptide / Enzyme – Metabolism (oxidative stress) / 1
EVPL / Q92817 / Envoplakin / Structural / 4
EXOSC4 / Q9NPD3 / Exosome component Rrp41 / Transcriptional control (cell cycle regulation – replication control) / 1
F16A11.2 / P90838 / Similar to C. elegens hypothetical 55.2 kD protein F16A11.2 / Uknown / 1
FABP5 / Q01469 / Fatty acid binding protein 5, epithelial / Other (lipid transport; keratinocyte differentiation) / 3
FAU1 / A3LUI4 / 5,10-methenyltetrahydrofolate synthetase / Enzyme / 1, 2
FBL / P22087 / Fibrallarin / Transcriptional control / 1
FBP1 / P09467 / Fructose-1,6-bisphosphatase 1 / Enzyme – Metabolism / 1
FBXW7 / Q969H0 / F-box protein 30 / Protein degradation / 2
FLJ00166 / Q8TEM7 / FLJ00166 protein / Translational control / 1
FLJ95410 / B2RBA8 / Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), (cDNA, FLJ95410, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade B(ovalbumin), member 6 (SERPINB6)) / Enzyme (serine protease inhibitor) / 1
FLNA / P21333 / Filamin 1 / Structural / 4
FOLH1 / Q04609 / Glutamate carboxypeptidase (folate hydrolase I) / Enzyme (folate uptake) / 1
FRAT2 / O75474 / GSK-3 binding protein FRAT2 / Cell proliferation / 1
FSCN / Q16658 / fascin homolog 1, actin-bundling protein / Structural / 2
FUBP1 / Q96AE4 / far upstream element binding protein / Translational control / 2
FUBP2
(KHSRP) / Q92945 / KH-type splicing regulatory protein / Translational control / 2
FUNDC2 / Q9BWH2 / hepatitis C virus core-binding protein 6 / Other / 1
G6PD / P11413 / Glucose-6-phosphate dehydrogenase / Enzyme – Metabolism / 1
GALK1 / P51570 / galactokinase 1 / Enzyme – Metabolism / 1
GAPDH / P04406 / Glyceraldehyde 3-phosphate dehydrogenase / Enzyme- Metabolism / 1, 3
GDNF / P39905 / Glial cell derived neurotrophic factor isoform 1 preproprotein / Other (differentiation of dopaminergic neurons) / 1
GFER / P55789 / ALR protein / Enzyme / 4
GLO1 / Q04760 / Glyoxalase I / Enzyme (oxidative stress) / 1
GLOD4 / Q9HC38 / CGI-150 protein / Enzyme / 1
GLUD1 / P00367 / glutamate dehydrogenase 1 / Enzyme / 2
GMEB2 / Q9UKD1 / Glucocorticoid modulatory element binding protein 2 / Other (replication of parvovavirus) / 1
GMFG / O60234 / Glia maturation factor, gamma / Growth factor / 1, 3
GMPS / P49915 / Guanine monophosphate synthetase / Transcriptional control (RNA and DNA synthesis) / 1
GNB2 / P62879 / guanine nucleotide binding protein beta polypeptide2 like 1 / Other (signal transduction) / 2
GOLGA1 / Q92805 / Golgin 97; gap junction protein, alpha 4, 37kD / Structural / 4
GOLGA4 / Q13439 / Golgin-245 / Structural / 4
GOLGB1 / Q14789 / Gigantin / Structural / 4
GPR98 / Q8WXG9 / Very large G protein-coupled receptor 1 / Receptor (central nervous system development) / 4
GPX1 / P07203 / Glutathione peroxidase 1 / Oxidative stress (enzyme) / 1
GRB2 / P62993 / growth factor receptor-bound protein 2 / Growth factor / 1
GRIA4 / P48058 / glutamate receptor, ionotropic, AMPA 4 / Receptor (signal transduction) / 4
GRIN1 / Q59GW0 / glutamate (NMDA) receptor 1, isoform NR1-2 / Other (receptor) / 2
GSTA1 / P08263 / Glutathione S-transferase / Enzyme (oxidative stress) / 1
H1F1OO / Q8IZA3 / oocyte-specific histone H1 / Transcriptional control / 1
H2AZ / P0C0S5 / H2A histone family, member Z / Transcriptional control / 1
H2BFD / Q99877 / H2B histone family, member D / Transcriptional control / 1
H2BFWT / Q7Z2G1 / H2B histone family, member J / Transcriptional control / 4
H3F3A / P84243 / Histone H3.3 / Transcriptional control / 1
HADH / Q16836 / Hydroxyacyl-Coenzyme A dehydrogenase / Enzyme – Metabolism / 1
HBA1 / P69905 / Hemoglobin alpha 1 globin chain / Other (oxygen transport) / 4
HBB / P6887 / Hemoglobin beta chain / Oxygen transport / 1
HBE / P02100 / Hemoglobin epsilon / Oxygen transport / 1
HBG1 / P69891 / Hemoglobin, gamma A / Other (oxygen transport) / 4
HBG2 / P69892 / G-gamma globin / Oxygen transport (fetal) / 1
HDAC10 / Q969S8 / histone deacetylase 10 isoform beta / Transcriptional control / 1
HEBP2 / Q9Y5Z4 / Heme binding protein 2 / Apoptosis (oxidative stress)\ / 1
HINT1 / P49773 / Histidine triad nucleotide binding protein 1 / Transcriptional control / 1
HIP2 (UBE2K) / P61086 / Huntingtin interacting protein 2 / Protein degradation / 1
HIST1H1A / Q02539 / Histone H1 family, member 1 / Transcriptional control / 4
HIST1H1T / P22492 / Histone H1t / Transcriptional control / 4
HIST1H4A / P62805 / H4 histone family, member A / Transcriptional control / 4
HISTH1C / P16403 / Histone H1.2 / Transcriptional control / 4
HISTH1D / P16402 / Histone H1.3 / Transcriptional control / 4
Hist2h3c1 / Q71DI3 / similar to histone protein Hist2h3c1 / Transcriptional control / 1
HLAB / P30475 / HLA-B associated transcript 1 / Immune system / 1
HMGB1 / P09429 / High mobility group box 1 / Binds to DNA (Transcriptional control) / 1
HNRNPA0 / Q13151 / Heterogeneous nuclear ribonucleoprotein A0 / Translational control / 1
HNRNPA1 / P09651 / Heterogeneous nuclear ribonucleoprotein A1 / Translational control / 1
HNRNPA2 / Q9TUP1 / Heterogeneous nuclear ribonucleoprotein A2/B1 / Translational control / 1
HNRNPA3 / P51991 / Heterogeneous nuclear ribonucleoprotein A3 / Translational control / 1
HNRNPC / P07910 / Heterogeneous nuclear ribonucleoprotein C-like protein—human / Translational control / 4
HNRNPD / Q14103 / Heterogeneous nuclear ribonucleoprotein D isoform c / Translational control (mRNA turn-over) / 1
HNRNPE
(PCBP1) / Q15365 / Poly(rC) binding protein 1 / Translational control / 1
HNRNPF / P52597 / Heterogeneous nuclear ribonucleoprotein F / Translational control / 3
HNRNPH1 / P31943 / Heterogeneous nuclear ribonucleoprotein / Translational control / 1
HNRNPK / P61978 / Heterogeneous nuclear ribonucleoprotein K isoform a / Translational control / 1
HNRNPL / P14866 / Heterogeneous nuclear ribonucleoprotein L / Translational control / 1, 4
HNRNPU / Q00839 / Heterogeneous nuclear ribonucleoprotein U / Translational control / 4
HNRPNM / P52272 / Heterogeneous nuclear ribonucleoprotein M / Translational control / 4
HNRPQ
(SYNCRIP) (NSAP1) / O60506 / Heterogeneous nuclear ribonucleoprotein Q / Translational control / 1
holE / P0ABT0 / Polymerase (DNA directed), theta / Transcriptional control / 4
HOXC9 / P31274 / Homeobox protein Hox-C9 / Cell cycle regulation (development – axis formation) / 1
HSP90AA1 / P07900 / Heat shock 90 kDa protein 1, alpha / Protein folding / 1
HSP90AB1 / P08238 / Heat shock 90 kDa protein 1, beta / Protein folding / 1, 2
HSPA1 / P08107 / Heat shock 70 kDa protein 1 / Protein folding / 4
HSPA5 / P11021 / Heat shock 70 kDa protein 5, BiP / Protein Folding (endoplasmic reticulum) / 1
HSPA6 / P17066 / Heat shock 70 kDa protein 6 / Protein folding / 4
HSPA8 / P11142 / Heat shock 70 kDa protein 8 isoform / Protein folding / 1, 2, 4
HSPA9 / P38646 / Heat shock 70 kDa protein 9B / Protein folding; Cell proliferation / 1, 2
HSPB1 / P04792 / Heat shock protein 27 / Oxidative stress (stress resistance) / 3
HSPB7 / Q9UBY9 / Heat shock 27kD protein 1 / Protein folding / 1
HSPC022 (RAC2) / P15153 / HSPC022 / Oxidative stress / 1
HSPC117 / Q9Y3I0 / C22orf28 (HSPC117) / Oxidative stress (?) / 2
HSPD1 / P10809 / Heat shock 60 kDa protein 1 / Protein folding (mitochondrion) / 1, 2
HYAL2 / Q12891 / hyaluronoglucosaminidase 2 / Structural / 1
IGF2R / P11717 / Insulin-like growth factor 2 receptor / Protein degradation (transport of proteins from Golgi complex and cell surface to lysosomes) / 1
IGHG1 / P01857 / IgG1 heavy chain / Immune system / 1
IGHM / P01871 / immunoglobulin mu heavy chain variable regio / Immune system / 1
IGKC / P01834 / immunoglobulin heavy chain variable region / Immune system / 1
IGLL1 / P15814 / immunoglobulin lambda chain variable region / Immune system / 1
IGLV (fragment) / Q8TE63 / Immunoglobulin light chain variable region / Immune system / 1
IL15 / P40933 / Interleukin 15 isoform 1 / Other (proliferation of T lymphocytes) / 1
IMPDH2 / P12268 / inosine monophosphate dehydrogenase 2 / Cell cycle regulation / 2
INSL4 / Q14641 / Insulin-like 4 (precursor) / Other (trophoblast development) / 1
ISG12 / Q7Z5R2 / interferon-induced ISG12c delta isoform / Other / 1
ITGA2B (PG2B) / P08514 / Platelet glycoprotein IIb / Other (platelet aggregation) / 1
ITGB4 / P16144 / Integrin beta 4 binding protein, eukaryotic translation (CD104) / Structural / 1
ITPA / Q9BY32 / Inosine triphosphatase / Enzyme / 1
KCNJ15 / Q99712 / ATP-sensitive inward rectifier potassium channel 15 / Other (channel) / 1
KIAA0063 / Q6IB81 / KIAA0063 protein / Uknown / 2
KIAA0819 / O94909 / KIAA0819 protein / Uknown / 2
KIF3C / O14782 / Kinesin family member 3C / Other (organelle transport through microtubules) / 1
KIT / P10721 / mast/stem cell growth factor tyrosine kinase receptor / Other (signal transduction) / 1
KRT1 / P04264 / Cytokeratin / Structural / 1
KRT10 / P13645 / Keratin 10 / Structural / 1, 4
KRT2 / P35908 / Keratin 2 / Structural / 1, 4
KTN1 / Q86UP2 / Kinectin 1 / Structural / 1
LCN2 / P80188 / Neutrophil gelatinase-associated lipocalin (NGAL) / Immune system (other) / 1
LDHA / P00338 / Lactate dehydrogenase A / Enzyme – Metabolism / 1
LECT1 / O75829 / chondromodulin I / Other (growth of cartilage) / 1
LGALS1 / P09382 / Beta-galactosidase binding lectin precursor / Enzyme – Metabolism / 1
LNPEP / Q9UIQ6 / Leucine aminopeptidase / Enzyme / 1
LPHN1 / O94910 / Latrophilin 1 / Other (regulation of exocytosis) / 4
LRP1 / Q07954 / Low density lipoprotein-related protein 1 / Other (embryonic development) / 4
LRP1B / Q9NZR2 / Low density lipoprotein-related protein 1 / Other (involved in receptor-mediated endocytosis) / 4
LRP2 / P98164 / Low density lipoprotein-related protein 2 / Other (endocytosis) / 4
LRRC7 / Q96NW7 / Densin-180 / Other (organization of synaptic cell contacts) / 4
LYPLA1 / O75608 / Lysophospholipase 1 / Enzyme / 1
LYST / Q99698 / Beige protein homolog; Lysosomal trafficking regulator / Other (vesicular trafficking) / 4
MACF1 / Q9UPN3 / Macrophin 1 isoform 4 / Structural / 4
MAP4 / P27816 / Microtubule-associated protein 4 / Structural / 4
MAX / P61244 / MAX protein isoform a / Transcriptional control / 2
MDH2 / P40926 / mitochondrial malate dehydrogenase / Enzyme – Metabolism / 1
MFN1 / Q8IWA4 / Mitofusin 1 / Other (mitochondrial morphology) / 1
MGAT2 / Q10469 / Alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase / Enzyme / 1
MKKS / Q9NPJ1 / McKusick-Kaufman syndrome protein / Other (limb, cardiac and reproductive system development) / 1
MLH3 / Q9UHC1 / DNA mismatch repair protein Mlh3 / DNA damage repairing / 4
MLLT10 (AF10) / P55197 / type II AF10 protein / Transcriptional control / 1
MMP2 / P08253 / matrix metalloproteinase 7 / Other (angiogenesis) / 1
MPHOSPH1 / Q96Q89 / M-phase phosphoprotein 1 / Cell cycle regulation (cytokinesis) / 4
MRLC2 / O14950 / Myosin regulatory light chain / Structural / 1
MRVI1 / Q9Y6F6 / Inositol 1,4,5-triphosphate receptor type 1 / Receptor (signal transduction) / 4
MSN / P26038 / Moesin / Structural / 1
MTL5 / Q9Y4I5 / Tesmin / Differentiation (spermatogenesis) / 1
MUC4 / Q99102 / Mucin 4 / Cell cycle regulation (repression of apoptosis) / 4
MUC5 / P98088 / Mucin 5 / Immune system (defense response) / 4
MYBPC2 / Q14324 / Myosin-binding protein C, fast type / Structural / 4
MYH10 / P35580 / Smooth muscle and non-muscle myosin
isoform 1 / Structural / 1
MYH11 / P35749 / Smooth muscle myosin heavy chain 11 / Structural / 4
MYH13 / Q9UKX3 / Myosin, heavy polypeptide 13, skeletal muscle; extraocular muscle myosin heavy chain / Structural / 4
MYH2 / Q9UKX2 / Myosin, heavy polypeptide 2, skeletal muscle, adult / Structural / 4
MYH3 / P11055 / Myosin heavy chain, fast skeletal muscle, embryonic (muscle embryonic myosin heavy chain) (SMHCE) / Structural / 4
MYH4 / Q9Y623 / Myosin, heavy polypeptide 4, skeletal muscle / Structural / 4
MYH8 / P13535 / Myosin heavy chain, perinatal skeletal muscle / Structural / 4
MYHCA (MYH6) / P13533 / Myosin alpha heavy chain / Structural / 4
MYHCB (MYH7) / P12883 / Myosin beta heavy chain / Structural / 4
MYO5A (MYH12) / Q9Y4I1 / Myosin Va (Myosin 5A) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin) / Structural / 4
MYO5C / Q9NQX4 / Myosin 5C / Structural / 4
MYO7A / Q13402 / Myosin VIIA; deafness, autosomal dominant 11; deafness, autosomal recessive 2 / Structural / 4
NAB1 / Q13506 / Transcriptional regulatory protein p54 / Transcriptional control / 1
NBAS / A2RRP1 / Neuroblastoma-amplified protein / Uknown / 4
NCL / P19338 / Nucleolin / Transcriptional control (Cell cycle regulation) / 1
NCOR2 / Q9Y618 / Nuclear receptor co-repressor 2 / Transcriptional control / 4
NCR3 / O14931 / natural cytotoxicity triggering receptor 3 / Immune system (natural killer) / 1
NDUFV2 / P19404 / NADH dehydrogenase (ubiquinone) flavoprotein 2 / Enzyme - Metabolism (oxidative stress) / 1
NEB / P20929 / Nebulin / Structural / 4
NEDD8 / Q15843 / Neural precursor cell expressed, developmentally down-regulated 8 / Protein degradation / 1
NETO1 / Q8TDF5 / neuropilin- and tolloid-like protein 1 isoform 1 / Other (neuronal circuitry) / 1
NEUROD6 / Q96NK8 / Neurogenic differentiation 6 / Cell cycle regulation (neuronal differentiation) / 1
NME1 / P15531 / Non-metastatic cells 1 protein / Cell proliferation / 1, 2
NONO / Q15233 / G01211 54 kDa protein / Transcriptional control / 1
NOTCH3 / Q9UM47 / Notch 3 / Transcriptional control / 1
NOV1 / Q8WZ69 / Putative uncharacterized protein C11orf40 / Uknown / 1
NRG1 / Q02297 / Neuregulin 1 isoform GGF / Other (growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells) / 1
NUDT5 / Q9UKK9 / Nudix (nucleoside diphosphate linked moiety X)-type motif 5 (HSP115) / Enzyme (oxidative stress) / 1
NUMA1 / Q14980 / Nuclear mitotic apparatus protein 1 / Transcriptional control / 4
OGG1 / O15527 / 8-oxoguanine DNA glycosylase isoform 1c / DNA damage repairing / 1
OLA1 / Q9NTK5 / Obg-like ATPase 1 / Other / 1
OSBPL8 / Q9BZF1 / Oxysterol-binding protein-like protein 10; oxysterol-binding protein-related protein 10; OSBP-related
protein 10 / Other (lipid transport) / 4
P0018H04.6 / Q5Z8V5 / FtsJ homolog 2 isoform b / Translational control / 1
P2RY6 / Q15077 / Pyrimidinergic receptor P2Y6 / Other (GPCR) / 1
PACAP / Q8WU39 / HSPC190 (Similar to RIKEN cDNA 2010) / Protein folding (apoptosis) / 1
PACSIN1 / Q9BY11 / protein kinase C and casein kinase substrate in neurons 1 / Other (vesicle trafficking) / 2
PAX6 / P26367 / Paired box protein Pax-6(aniridia protein) / Cell cycle regulation (eye, nose, central nervous system and pancreas development) / 1
PCDC5 / O14737 / Programmed cell death 5 / Cell cycle regulation (apoptosis) / 1
PCNA / P12004 / Proliferating cell nuclear antigen (PCNA) / Cell cycle regulation / 1, 2
PCSK2 / P16519 / Proprotein convertase subtilisin/kexin type 2 / Other (secretory vesicles) / 1
PDHA1 / P08559 / Dihydrolipoamide dehydrogenase precursor / Enzyme – Metabolism / 1
PDHB / P1117 / Pyruvate dehydrogenase E1 component subunit beta, mitochondrial / Enzyme – Metabolism / 3
PDIA3 / P30101 / Glucose regulated protein, 58 kD / Protein folding (S-S bond rearrangement) / 1
PDK1 / Q15118 / Pyruvate kinase 3, isoform 1 / Enzyme – Metabolism / 1, 2
PDK3 / Q15120 / Pyruvate kinase, muscle, pyruvate kinase-3 / Enzyme – Metabolism / 1
PEBP1 / P30086 / Prostatic binding protein (PBP) / Other (pre-synaptic cholinergic neurons) / 2
PEX1 / O43933 / Peroxisome biogenesis factor 1 / Protein degradation / 4
PFDN2 / Q9UHV9 / Prefoldin 2 / Protein folding / 1
PFKFB2 / O60825 / 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase / Enzyme – Metabolism / 1
PGK1 / P00558 / Phosphoglycerate kinase 1 / Enzyme – Metabolism / 1, 3
PGAM1 / P18669 / Phosphoglycerate mutase 1 / Enzyme – Metabolism / 1
PGLS / O95336 / 6-phosphogluconolactonase / Enzyme – Metabolism / 1
PHB / P35232 / Prohibitin / Transcriptional control (inhibits DNA synthesis for negative regulation of cell proliferation) / 1, 2
PKM2 / P14786 / Pyruvate kinase isozymes M1/M2 (p58) / Enzyme – Metabolism / 1, 3
PLA2G1B / P04054 / phospholipase A2, group IB (pancreas) / Enzyme / 1
PLEC1 / Q15149 / Plectin 1 / Structural / 4
PLIN3 / O60664 / Perilipin 3 (cargo selectin protein) / Other (lipid transport) / 3
POLR3C / Q9NW08 / RNA polymerase III transcription initiation factor B00 short / Tranascriptional control / 4
PPARG / P37231 / Steroid receptor RNA activator isoform 3 (Peroxisome proliferator-activated receptor gamma) / Transcriptional control (oxidative stress; beta oxidation of fatty acids – Metabolism) / 1
PPIA / P62937 / Peptidylprolyl isomerase A (cyclophilin) / Protein folding / 1, 2
PPIE / Q9UNP9 / Peptidyl-Pro cis trans isomerase / Protein folding / 1
PRDX3 / P30048 / Peroxiredoxin 3 / Enzyme (oxidative stress) - Metabolism / 1
PRDX6 / P30041 / Peroxiredoxin 6 / Enzyme (oxidative stress) / 1
PRL / P01236 / Prolactin / Other (promotes lactation) / 1
PRX / Q9BXM0 / Periaxin / Other (myelin deposition) / 4
PSMA3 / P25788 / Proteasome alpha 3 / Protein degradation / 1
PSMA5 / P28066 / Proteasome alpha 5 subunit / Protein degradation / 1
PSMA6 / P60900 / Proteasome alpha 6 subunit / Protein degradation / 1
PSMB6 / P28072 / Proteasome beta 6 subunit / Protein degradation / 1
PSMB9 / P28065 / Proteasome beta 9 subunit isoform 1 / Protein degradation / 1
PSME1 / Q06323 / Proteasome activator subunit 1 / Protein degradation / 1
PSME2 / Q9UL46 / Proteasome activator subunit 2 / Protein degradation / 1
PTBP1 / P26599 / Polypyrimidine tract-binding protein 1 isoform a / Translational control / 1
PTD004 / Q53SW9 / Putative GTP-binding protein PTD004 (PRO2455) / GTP-binding (other) / 1
RAB12 / Q6IQ22 / Similar to RAB12 protein / Other (transport and assembly of tight junction proteins) / 1
RAB13 / P51153 / RAB13 protein / Other (transport and assembly of tight junction proteins) / 1
RAB14 / P 61106 / Rab14 / Other (vesicular trafficking, neurotransmitter release) / 1
RAB17 / Q9H0T7 / Rab17 / Other (transcellular transport) / 1
RAB2B / Q8WUD1 / RAB2B / Other (transport from ER to Golgi apparatus) / 1
RAB32 / Q13637 / RAB32, member RAS oncogene family / Cell cycle regulation (mitochondrial fission) / 1
RAB7 / P51149 / RAB7, member oncogene family RAS 7 / Other (maturation of the phagosome) / 2
RAD26L / Q5T890 / Excision repair cross-complementing rodent repair deficiency, complementation group 6; Rad26
(yeast) homolog / DNA damage repairing / 4
RAD50 / Q92878 / RAD50 / DNA damage repairing / 4