Manning, P. J., D. H. Ringler, and C. E. Newcomer, eds. 1994. The biology of the laboratory rabbit, 2nd ed. Academic Press, San Diego, CA.
Chapter 8 - Bacterial Diseases, pp. 129-162
QUESTIONS
1. What is the most common bacterial pathogen of the laboratory rabbit?
a. Bordatella bronchiseptica
b. Pasteurella multocida
c. Clostridium spiroforme
d. Bacillus piliformis
2. What is the most common clinical manifestation of Pasteurellosis in rabbits?
a. pneumonia
b. otitis media
c. rhinitis
d. abscesses
3. What percentage of rabbits harboring Pasteurella in their nares show no clinical
signs of rhinitis?
a. 10 %
b. 20 %
c. 50%
d. 80%
4. What is the “ common name “ for Rhinitis caused by Pasteurella?
a. sniffles
b. snuffles
c. Tyzzers disease
d. Schmorl’s disease
5. Pasteurella grows well on what kind of agar?
a. blood agar
b. MacConkeys’s agar
c. XLD agar
d. Agar-agar
6. The indirect hemagglutination assay ( IHA) for Pasteurella multocida identifies ?
number of serotypes ?
a. 16
b. 4
c. 7
d. 5
7. Which bacteria in rabbits can cause a clinical sign of epiphora ?
a. Bordatella bronchiseptica
b. Pasteurella multocida
c. Clostridium spiroforme
d. Bacillus piliformis
8. True or False: Pasteurellosis can be spread venereally?
9. True or False: At the present time there is no commercially available vaccine for
Pasteurellosis ?
10. True or False; There are no serologic tests for Pasteurella ?
11. The antibiotic of choice to treat Pasteurella infections in rabbits is?
a. Gentamycin
b. Tetracycline
c. Penicillin
d. Trimethoprim-Sulfadiazine
12. True or False Virulence of a specific isolate of Pasteurella is dependent upon the
plasmid it carries?
13. Enterotoxemia in rabbits is caused by?
a. Clostridium difficile
b. Clostridium perfringens Type E
c. Clostridium spiroforme
d. Clostridium cuniculi
14. The etiologic agent that causes Enterotoxemia is normally present in the rabbit intestine? T/F
15. In which animal was Tyzzers disease first identified in 1917?
a. BALB/c mouse
b. Japanese waltzing mice
c. New Zealand White rabbit
d. Watanabe rabbit
16. True or False Bacillus piliformis grows readily on most microbiological media?
17. Which of the following stains will NOT stain Bacillus piliformis?
a. Warthin-Starry stain
b. Periodic acid-Schiff
c. Giemsa
d. Tyzzer’s stain
18. E.coli is recognized as a primary pathogen in rabbits? T/F
19. Which enteropathogenic strain of E.coli is most common in the U. S.?
a. O15:H
b. 028:H2
c. 0103:H2
d. 0132:H2
20. What are the two ages when rabbits commonly get colibacillosis?
a. 1-2 weeks and 6-8 weeks
b. 2-4 weeks and adult
c. 1-2 weeks and 4-6 weeks
d. 1-2 weeks and adult
21. Histological findings of colibacillosis in rabbits includes all but….
a. atrophy and fusion of villi in the intestine
b. epithelial cells are flattened and disorganized, and ulcers may be present
c. infiltration of the lamina propria by PMN leukocytes and submucosal edema
d. perivascular cuffing
22. True or False : Salmonella bacteria are lactose fermenters.?
23. True or False: Rabbits can be carriers of Salmonella?
24. Salmonella can be grown on all of the following agar except….?
a. SS agar
b. brilliant green agar
c. Hektoen agar
d. PEA agar
25. Salmonella is considered a zoonotic bacteria ? T/F
26. Pathogenic Staph can be distinguished from non pathogenic Staph by what test?
a. catalase test
b. coagulase test
c. coagulum test
d. optochin test
27. Staph aureus infection in rabbits is usually considered a ? infection?
a. pathogenic
b. opportunistic
c. zoonotic
d. rare
28. Clinical signs of Staph infection in rabbits are similar to which other rabbit disease?
a. Salmonella
b. Pasteurella
c. Listeriosis
d. Bordetella bronchiseptica
29. Rabbit syphilis is caused by?
a. Treponema pallidum
b. Treponema cuniculi
c. Treponema syphilisii
d. Treponema kutcheri
30. True of False: A vaccine for human syphilis has been made from the agent for rabbit syphilis?
31. Which inbred strain of rabbit is most sensitive to Treponema infection?
a. AC/J
b. ACEP/J
c. X/J
d. III/J
32. What is the antibiotic of choice to treat rabbit syphilis?
a. streptomycin
b. penicillin
c. Trimethoprim-sulfadiazine
d. Enrofloxacin
33. What is the most suitable screening test for rabbit syphilis?
a. VDRL
b. RPR
c. FTA-ABS
d. MHA-TP
34. Fusobacterium necrophorum causes a disease called ? in rabbits?
a. Tyzzer’s
b. Schmorl’s
c. Snuffles
d. Pododermatitis
35. Fusobacterium necrophorum culture requires
a. aerobic conditions
b. anaerobic conditions
c. microaerophilic conditions
36. Listeriosis in rabbits is more common in?
a. pregnant females
b. breeding males
c. suckling rabbits
37. The most consistent pathologic lesion associated with Listeria in rabbits is
a. focal hepatic necrosis
b. Diffuse hepatic necrosis
c. granulomatous kidneys
d. nephritis
38. Which mycobacterium is most often found in rabbits?
a. M. avium
b. M.tuberculosis
c. M. bovis
d. M. paratuberculosis
39. Tularemia was first described in which animal?
a. Oryctolagus cuniculus
b. Lepus articus
c. Citellus beecheyi
d. Sylvilagus audubonii
40. Francisella tularensis is only found in rabbits and hares.? T/F
41. Rabbits should not be housed with guinea pigs due to the possible transmission of which bacteria?
a. Actinomyces
b. Actinobacillus
c. Bordetella
d. Brucella
42. A green discoloration on the dewlap of a rabbit would make you think of ?
a. Streptococcus
b. Staphylococcus
c. Pseudomonas
43. Which of the following is rare in rabbits yet common in guinea pigs?
a. Bordatella bronchiseptica
b. Pasteurella multocida
c. Yersinia pseudotuberculosis
d. Streptococcus ulcerans
44. True or False, Rabbits with CAR bacillus have severe clinical disease with pathognomonic lung lesions?
45. Snowshoe hares( Lepus americanus) are sensitive to what infectious disease?
a. Chlamydia trachomitis
b. Chlamydia psittici strain A
c. Chlamydia psittici strain M56
d. Chlamydia lepus
46. To be sure a rabbit is Pasteurella free the blue book suggests culturing X times?
a. twice, two weeks apart
b. three times
c. 5 times over a 3 month period
d. once is sufficient
47. Which antibiotic will inhibit growth of most nasopharyngeal flora except Pasteurella?
a. Tetracycline
b. Penicillin
c. Albon
d. Clindamycin
48. What kind of swab should you use to culture the rabbits nose ?
a. calcium alginate urethral swab
b. cotton swab
c. Whatman Omniswab
Rabbit Blue Book Chapter 8 Answers:
1. B, page 131 31. C, page 152
2. C, page 131 32. B, page 154
3. C, page 133 33. D, page 154
4. B, page 133 34. B, page 154
5. A, page 132 35. B, page 155
6. D, page 132 36. A, page 155
7. B, page 134 37. A, page 156
8. T, page 133 38. C, page 157
9. T, page 139 39. C, page 158
10. F, page 139 40 F, page 158
11. F, page 138 41. C, ACLAM CD -ROM
12. F, page 138 42. C, page 162
13. C, page 142 43. C, page 162
14. F, page 142 44. F, page 160
15. B, page 143 45. C, page 160
16. F, page 143 46. B, page 139
17. D, page 145 47. D, page 139
18. F, page 146 48. A, page 139
19. A, page 147
20. C, page 147
21. D, page 147
22. F, page 149
23. T, page 149
24. D, page 149
25. T, page 149
26. B, page 150
27. B, page 151
28. B, page 150
29. B, page 151
30. F, page 151