Preliminary programme

Session A

Why do we need Physiology in the cath lab?

Jaydeep Sarma

08.50Introduction and overview: UK perspective , why is it important to use adjunctive technology in the cath lab.

Key points: Importance of coronary physiology in revascularisation

European vs. global practice

UK perspective

Matthias Schmitt

09.00Imaging of the heart in CAD: epicardial topographic data vs: functional perfusion imaging

Key points: The evolution of non-invasive cardiac imaging

Current state of the art

The use of anatomical and functional imaging in CAD

Saqib Chowdhary

09.15Is angiography redundant in modern coronary intervention?

Key points:

The limitations of angiography in coronary revascularisation (both CABG and PCI)

How intra-coronary imaging aids revascularisation strategy and techniques

New developments in intra-coronary imaging

Bernard de Bruyne

09.30The need for functional evaluation

Coronary artery physiology primer

Key points:Basic principles of coronary flow

Overview of the concepts and derivation of FFR

Application of FFR in the cath lab

Session B

Practical issues in evaluating coronary physiology in the cath lab

Chairs: Faz Fath-Ordoubadi / Neal Uren

Key points: General (2min) introduction to the use of

Mobile and on-table analysers

Pre-packaged drugs

Technician and non-physician cath lab worker familiarity with techniques

Ganesh Manoharan

09.45Setting up FFR in your cath lab: the ideal world

Key points: Patient preparation, access choices

Guide catheter selection and technique

Wire calibration and equalisation

Engagement and wire technique

Use of analyser software and data acquisition

Andreas Baumbach

10.0Pharmacology

Key points:Concepts behind drugs used for FFR evaluation

Vessel preparation

Drug choices

Drug delivery routes

Drug infusion rates

Phil MacCarthy

10.15Pitfalls, artefacts and caveats in physiological assessment

Key points:

Difficult areas: Severe LV dysfunction, Cardiomyopathy, Hypertrophy

Ostial damping

Drift

Contribution of collaterals

Session C

The use of coronary physiology in real-life Clinical Practice

Special anatomy

10.35Saqib ChowdharyLeft Main Stem

Key points: Use of IVUS vs. FFR. Does LMS flow allow for FFR measurements? Is IVUS more reliable? Are IVUS criteria always relevant?

10.45Doug FraserBifurcations.

Key points: Use of FFR evaluation of side branch stenoses. Assessment of side branch results post bifurcation stenting

10.55Neal UrenDiffuse disease, serial stenoses

Key points: Evaluation of multiple lesions in single vessels. Use of steady state hyperaemia. The role of pullbacks in decision making in serial stenoses. Impact of tandem lesions on individual FFR readings in diffuse disease

11.15Interactive Clinical case (serial stenoses, +/- bifurcation)

Key discussants/operators:Richard Levy/Bernard De Bruyne

Key points: Introduction of clinical case

Panel discussants: Neal Uren, Andreas Baumbach, Faz Fath-Ordoubadi

Lunch

Session C

Multi-vessel disease & FAME

1.15 Introduction Andreas Baumbach

Key points: overview. The role of PCI in multi vessel disease

Introduction to Keynote speaker

Bernard De Bruyne

1.20Keynote lecture: Beyond FAME

Key points: Background to FAME study

Importance of the study

Impact on clinical practice

Interactions with other major recent studies: SYNTAX and COURAGE

Future developments and investigations

1:45Interactive/ live clinical Case Multi-vessel disease

Key discussants/live operators

Saqib Chowdhary/Phil MacCarthy

Key points: Introduction and clinical background to clinical case

Panelists: Doug Fraser, Ganesh Manoharan, Bernard De Bruyne

Session D

Moving forward with FFR

Use of invasive physiological tools in special clinical settings

3:05Bernard De BruyneACS

Key points: The role of FFR evaluation in ACS. Is it useful? Is it meaningful?

3.15Andreas BaumbachSTEMI

Key points:

Theory of FFR in post MI patients

Changes in flow in acute vs. chronic MI

Time frame for meaningful results with FFR post MI

Implications of loss of muscle mass on FFR

3.25Neal UrenMicrocirculatory dysfunction

Key points:

Background concept of microcirculation

Microcirculatory dysfunction in cardiac disease

How to measure it (non-invasive, invasive)

Relevance to PCI

3.35Ganesh ManoharanNon-coronary arterial flow

Key points: Is the concept of flow useful outside the heart?

Do the same principles apply?

Models of non-coronary flow evaluation

Pressure wire evaluation in renal arteries

3:45 Wrap up and close

Jaydeep Sarma