Name: ______Date: ______

Unit L Notes #3 - Gas Exchange

- When carbon dioxide ______, only a small amount of it (9%) reaching the blood is held in simple solution. (this

portion is carried as______)

- Another ______% attaches directly to the ______to form

______(______).

- The______, the remaining _____%, combines with ______to form

______(HCO3-) and ______(H+).

- Each time blood passes through the tissues; it picks up large quantities of carbon dioxide. This then reacts with water to form Bicarbonate (______) and Hydrogen Ions (____).

Ex. ______+ ______à ______à ______+ ______

* The reaction above takes place ______with the help

of an ______called “ ______”- This reaction can be reversed by the same enzyme as blood enters the pulmonary capillaries of the lungs.

- There are many substances in the blood capable of binding to the excess free

hydrogen ions ______. ______

is one of the most important of these substances. When ______(H+) combines with the ______(____), the ______

______. The Hb binds with the H+ to make (______) or “ ______”

A) Gas Exchange in Tissues : ______

1.CO2 diffuses into the blood from the cells.

2.CO2 joins with water to make Bicarbonate and Hydrogen Ions thanks to

______

CO2 + ______à ______+ ______

3. Most of the ______is picked up by the combined form of O2 and

hemoglobin (______). The taking up of H+ by HbO2

(produces HHb), causing the ______to release its oxygen easily.

- The H+ concentration (______near tissue) and the slight ______

______alters the hemoglobin structure (Slight______)

causing it to ______easily.

4.______moving from an area of high concentration to an area of low concentration.

- The blood leaving the tissues now contains large quantities of hemoglobin, which is

free of oxygen but carrying ______, at this point these Hb’s are called

______(______) The blood also contains large amounts of

______(______). No further changes occur until the blood reaches the lungs.

B) Gas Exchange in the Lungs – ______

* The environment near the lungs is different than near the tissues, the capillaries near the lungs are at a ______temperature and at a ______

1.High concentration of Oxygen in lungs. ______

______.

2.The reduced hemoglobin (HHb)______causing it to lose its H+ to become ______(Hb). This Deoxyhemoglobin readily picks up oxygen to form Oxyhemoglobin (HbO2)

Ex. ______à ______+ ______à _____+ ______à ______

3.H+ picked up by Bicarbonate to produce CO2 + H2O

Ex. ______+ ______à ______à ______+ ______

4.The ______where it is expelled by normal breathing.

***NOTE: H+ does not accumulate because as soon as it is released from HHB, it combines with HCO3- to release Carbon dioxide.

- Hemoglobin is essential in the blood because it ______
______
______

The Respiratory System : Review #2

Respiratory System : (Learning Outcomes L5 – L8)

L.O. L – 5 Lungs, Pleural Membranes, Ribs, and Diaphragm

___ 1. What makes up the floor of the chest cavity?

___ 2. What chemicals are primarily responsible for stimulating us to breathe?

___ 3. What is the normal shape of the diaphragm?

___ 4. What happens to the diaphragm when it contracts?

___ 5. What happens to the ribs when the intercostal muscles contract?

___ 6. When the ribs and diaphragm contract, what happens to the overall volume of the

thoracic cavity?

___ 7. What happens to the air pressure within the lungs when a vacuum is produced??.

L.O. L – 6 Nervous System Control

___ 1. The levels of what two substances are the main stimuli for the chemoreceptors in the base of the brain to send an impulse to stimulate us to inhale?

___ 2. These substances stimulate what part of the brain?

OVER à

___ 3. Some receptors are able to detect low oxygen concentration. Give two locations

for these chemoreceptors.

___ 4. Where are the stretch receptors located that detect that the lungs have expanded?

___ 5. What happens when these receptors send their message to the Medulla notifying

it that that the lungs are full?

____ 6. Name the nerve that the nerve impulse travels on its way from the stretch

receptors to the Medulla.

L.O. L – 7 Internal and External Respiration

___ 1. During internal respiration as CO2 diffuses into the blood, some of it directly

joins with what molecule, and what is the new combined molecule called?

____2. What happens to the majority of the CO2 that leaves the tissue? (p. 290)

___ 3. Name the enzyme that speeds up the above reaction, and where are these

enzymes located?

___ 4. The hydrogen ions [H+] that are produced during this reaction are taken up by

what molecule, and what is the name of this new combined form of the molecule?

___ 5. During EXTERNAL respiration, oxygen from where to where?

___ 6. What must happen to carbaminohemoglobin (HbCO2) and reduced hemoglobin

(HHb) in order for them to form deoxyhemoglobin (Hb)?

____7. When oxygen binds onto Deoxyhemoglobin, what name is given to this new form

Of Hemoglonin (Hb) and give its short-hand version or symbol?

___ 8. The Hydrogen Ions are picked up by Bicarbonate to undergo a reaction to

produce what two molecules?

___ 9. What happens to the CO2 that is produced?

___ 10. List three roles that Hemoglobin plays in the blood in the blood?

___ 11. Give the chemical formula for the Bicarbonate Ion.

L.O. L – 8 Oxyhemoglobin, Carbaminohemoglobin, and Bicarbonate Ions

___ 1. List three ways that carbon dioxide can be transported by the blood. Give the

percentage that is carried in each method?

___ 2. Carbon Dioxide is mainly carried in the form of what Ion?

___ 3. Give the name for a combination of hemoglobin carrying oxygen.

___ 4. Where is the partial pressure of Oxygen the greatest: in tissues or in the lung

alveoli?

___ 5. What happens to the amount of oxygen held by hemoglobin when the partial

pressure of oxygen decreases?

___ 6. Where is the partial pressure of oxygen least: in tissues or in lung alveoli?

___ 7. What effect does a slightly lower temperature have on the amount of oxygen

carried by hemoglobin?

___ 8. Where in the circulatory system is the temperature lowest?

____9. What happens to Oxyemoglobin when the temperature rises at the internal

tissues?