Unit Iresearch and Its Methodologies (With Examples)9(12)

/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 1 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

UNIT IRESEARCH AND ITS METHODOLOGIES (WITH EXAMPLES)9(12)

Objectives of research, research process – observation, analysis, inference, hypothesis, axiom, theory, experimentation, types of research (basic, applied, qualitative, quantitative, analytical etc). Features of translational research, the concept of laboratory to market (bench to public) and Industrial R&D.

Objective: To provide a conceptual introduction to research and its methodologies.

Session No / Topics to be covered / Time allocation / Books Referred / Teaching Methods
1 / Objectives of Research / 50 min / TB -1 (1-24) / LCD/PPT
2 / Types of Research / 50 min / TB- 4(8-13) / LCD/PPT
3 / Basic Research / 50 min / TB- 4(8-13) / LCD/PPT
4 / Applied research / 50 min / TB- 4(8-13) / LCD/PPT
5 / Qualitative Research / 50 min / TB- 4(8-13) / LCD/PPT
6 / Quantitative Research / 50 min / TB- 4(8-13) / LCD/PPT
7 / Analytical Research / 50 min / TB- 4(8-13) / LCD/PPT
8 / Research process – Observation analysis and inference / 50 min / TB-41 (15-70) / LCD/PPT
9 / Concepts of hypothesis / 50 min / TB -1 (1-24), TB- 4(72-79) / LCD/PPT
10 / Axiom theory / 50 min / TB -1 (1-24), TB- 4(72-79) / LCD/PPT
11 / Translational Research (bench to public) / 50 min / TB- 1(15-79) / LCD/PPT
12 / Industrial R&D / 50 min / TB- 1 (15-79) / LCD/PPT
/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 2 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

UNIT IIRESEARCH IN BIOTECHNOLOGY – AN OVERVIEW 9(12)

Biological systems and their characteristics that influence the type and outcome of research, Exploratory and product-oriented research in various fields of biotechnology (health, agri, food, industrial etc) – types of expertise and facilities required. Interdisciplinary nature of biotech research, sources of literature for biotech research.

Objective: To provide an overview about research in biotechnology.

Session No / Topics to be covered / Time / Books Referred / Teaching Methods
Biological systems and their characteristics / 50 min / TB- 1 (29-37) / LCD/PPT
Outcome of biological research / 50 min / TB- 1(37-45) / LCD/PPT
Exploratory and product-oriented research in various fields of biotechnology / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Exploratory and product-oriented research in various fields of biotechnology / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Exploratory and product-oriented research in various fields of biotechnology / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Exploratory and product-oriented research in various fields of biotechnology / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Exploratory and product-oriented research in various fields of biotechnology / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Types of expertise and facilities required. / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Interdisciplinary nature of biotech research. / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Sources of literature for biotech research. / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
Summary of Unit II / 50 min / TB- 1(1-55), TB- 4 (15-79) / LCD/PPT
Revision of Unit I and Unit II / 50 min / TB- 1(1-55), TB- 4 (15-79) / LCD/PPT
/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 3 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

UNIT IIIEXPERIMENTAL RESEARCH: BASIC CONCEPTS IN DESIGN AND METHODOLOGY 9 (12)

Precision, accuracy, sensitivity and specificity; variables, biochemical measurements, types of measurements, enzymes and enzymatic analysis, antibodies and immunoassays, instrumental methods, bioinformatics and computation, experimental planning – general guidelines.

Objective:To provide basic concepts in design and methodology of experimental research.

Session No / Topics to be covered / Time / Books Referred / Teaching Methods
1 / Precision, accuracy, sensitivity and specificity / 50 min / TB- 1(55-94, TB-3(231-253) / LCD/PPT
2 / Biochemical measurements / 50 min / TB- 1(55-94) / LCD/PPT
3 / Types of measurements / 50 min / TB- 1(55-94) / LCD/PPT
4 / Enzymes and Enzymatic analysis / 50 min / TB- 5, Open source –recent research article in Biotechnology / LCD/PPT
5 / Antibodies / 50 min / TB-5, Open source –recent research article in Biotechnology / LCD/PPT
6 / Immunoassays / 50 min / TB-5, Open source –recent research article in Biotechnology / LCD/PPT
7 / Instrumental methods / 50 min / TB- 1(361-374) / LCD/PPT
8 / Bioinformatics and computation / 50 min / TB- 1(361-374) / LCD/PPT
9 / Experimental planning –Part I / 50 min / TB- 3(49-65)
TB-4(83-142) / LCD/PPT
10 / Experimental planning – Part II / 50 min / TB- 3(49-65)
TB-4(83-142) / LCD/PPT
11 / Experimental planning – Part III / 50 min / TB- 3(49-65)
TB-4(83-142) / LCD/PPT
12 / Review of Unit III / LCD/PPT
/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 4 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

UNIT IVRESULTS AND ANALYSIS9(12)

Importance and scientific methodology in recording results, importance of negative results, different ways of recording, industrial requirement, artifacts versus true results, types of analysis (analytical, objective, subjective) and cross verification, correlation with published results, discussion, outcome as new idea, hypothesis, concept, theory, model etc.

Objective: To impart knowledge about the various ways of interpreting and analysis of results

Session No / Topics to be covered / Time allocation / Books Referred / Teaching Methods
1 / Importance and scientific methodology in recording results / 50 min / TB- 1(55-68, 95-121) / LCD/PPT
2 / Importance of negative results / 50 min / TB- (195-121) / LCD/PPT
3 / Different ways of recording-Sampling / 50 min / TB- 1(152-183) / LCD/PPT
4 / Sampling techniques / 50 min / TB- 1(152-183) / LCD/PPT
5 / Artifacts versus true results / 50 min / TB- 1 (122-151) / LCD/PPT
6 / Types of analysis (analytical, objective, subjective) / 50 min / TB-1 (122-151, 184-343) / LCD/PPT
7 / Correlation with published results / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
8 / Discussion of results / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
9 / Discussion of results / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
10 / Discussion of results / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
11 / Research outcome as new idea, hypothesis, concept, theory, model etc. / 50 min / Open source –recent research article in Biotechnology / LCD/PPT
12 / Review of Unit IV / 50 min / LCD/PPT
/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 5 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

UNIT VSCIENTIFIC AND TECHNICAL PUBLICATION 9 (12)

Different types of scientific and technical publications in the area of biotechnology, and their specifications, Ways to protect intellectual property –Patents, technical writing skills, definition and importance of impact factor and citation index - assignment in technical writing

Objective: To impart training on technical writing and the importance of publication.

Session No / Topics to be covered / Time / Books Referred / Teaching Methods
1 / Different types of scientific and technical publications in the area of biotechnology / 50 min / TB-1 (344-359) / LCD/PPT
2 / Ways to protect Intellectual property / 50 min / TB-2(355-377) / LCD/PPT
3 / Intellectual Property, Patents / 50 min / TB-2(355-377) / LCD/PPT
4 / Technical writing skills / 50 min / TB- 1 (344-359) / LCD/PPT
5 / Definition and importance of impact factor. / 50 min / TB- 2( 333-344), Open source - Online / LCD/PPT
6 / Definition and importance of Citation Index. / 50 min / TB- 2( 333-344), Open source - Online / LCD/PPT
7 / Training on technical writing / 50 min / TB- 2( 297-330), TB- 3 (entire) / LCD/PPT
8 / Training on technical writing -ethics / 50 min / TB- 2 (347-353) / LCD/PPT
9 / Evaluation and Feedback on technical writing assignment / 50 min / - / LCD/PPT
10 / Evaluation and Feedback on technical writing assignment / 50 min / - / LCD/PPT
11 / Evaluation and Feedback on technical writing assignment / 50 min / - / LCD/PPT
12 / Review of Unit V / 50 min / TB-1 (344-359), TB-2(355-377) / LCD/PPT
/ LESSON PLAN / LP- BY7023
LP Rev. No: 00
Date:31.12.2014
Page 6 of 6
Sub Code & Name : BY7023Research & Research Methodology in Biotechnology
Unit: I Branch: M. Tech (Bio Technology) Semester : II

Course Delivery Plan 45(60)

Week / 1 / 2 / 3 / 4 / 5 / 6 / 7 / 8 / 9 / 10 / 11 / 12 / 13 / 14 / 15
Units / I / II / III / IV / V

Text Books

1. C. R. Kothari, “Research Methodology - Methods and Techniques”, New Age International publishers, New Delhi, 2004.
2. R. Ganesan, “Research Methodlogy for Engineers”, MJP Publishers, Chennai 2011.
3. Guide to Publishing a Scientific paper, Ann M. Korner, 2004, Bioscript Press
4. Ranjit Kumar, “Research Methodology- A step by step guide for beginners”, Pearson Education, Australia, 2005.
5. M.M. Ranga, “Animal Biotechnology”, Student Edition, Jodhpur, 2006.

Prepared by / Approved by
Signature
Name / Dr. Nalinkanth V. Ghone / Dr. S. Sulochana
Designation / Assoc. Prof.
Dept. of Bio Technology / Prof. & Head
Dept. of Bio Technology
Date / 31.12.2014 / 31.12.2014

ANNA UNIVERSITY, CHENNAI-600 025

AFFILIATED INSTITUTIONS

REGULATIONS – 2013

M.TECH. BIOTECHNOLOGY

SEMESTER II

Elective VI

BY7023Research & Research Methodology in Biotechnology L T P C

3 0 0 3

UNIT IRESEARCH AND ITS METHODOLOGIES (WITH EXAMPLES)9

Objectives of research, research process –observation, analysis, inference, hypothesis, axiom, theory, experimentation, types of research (basic, applied, qualitative, quantitative, analytical etc). Features of translational research, the concept of laboratory to market (bench to public) and Industrial R&D.

UNIT IIRESEARCH IN BIOTECHNOLOGY –AN OVERVIEW 9

Biological systems and their characteristics that influence the type and outcome of research, Exploratory and product-oriented research in various fields of biotechnology (health, agri, food, industrial etc) –types of expertise and facilities required. Interdisciplinary nature of biotech research, sources of literature for biotech research.

UNIT IIIEXPERIMENTAL RESEARCH: BASIC CONCEPTS IN DESIGN ANDMETHODOLOGY 9

Precision, accuracy, sensitivity and specificity; variables, biochemical measurements, types of measurements, enzymes and enzymatic analysis, antibodies and immunoassays, instrumental methods, bioinformatics and computation, experimental planning – general guidelines.

UNIT IVRESULTS AND ANALYSIS9

Importance and scientific methodology in recording results, importance of negative results, different ways of recording, industrial requirement, artifacts versus true results, types of analysis (analytical, objective, subjective) and cross verification, correlation with published results, discussion, outcome as new idea, hypothesis, concept, theory, model etc.

UNIT VSCIENTIFIC AND TECHNICAL PUBLICATION 9

Different types of scientific and technical publications in the area of biotechnology, and their specifications, Ways to protect intellectual property –Patents, technical writing skills,definition and importance of impact factor and citation index -assignment intechnical writing

TOTAL:45 PERIODS

TEXT BOOKS AND REFERENCES

1.Essentials of Research Design and Methodology Geoffrey R. Marczyk, David DeMatteo, David Festinger, 2005 John Wiley & Sons Publishers, Inc.

2. Biochemical Calculations: How to Solve Mathematical Problems in General Biochemistry, 2nd Edition, Irwin H. Segel, 1976John Wiley & Sons Publishers, Inc

3. Guide to Publishing a Scientific paper, Ann M. Korner, 2004, Bioscript Press