RESPT 1213 Pharmacology page 1
Unit 2 Bronchodilators Part IICorrected 2/26/08
Name:Date: 2007
1.Cholinergic antagonists work on the bronchial smooth muscle by:
- Stimulation of the Beta II receptor
- Blocking the Beta II receptor
- Blocking the cholinergic receptor
2.A cholinergic antagonist will raise the HR by:
- Stimulation of the beta I receptor on the myocardium
- Stimulation of the Beta II receptor on the myocardium
- Blocking the cholinergic receptor on the myocardium that should decrease the HR
3.A cholinergic antagonist will reduce mucus production by:
- Stimulation of the alpha receptor on the submucosal gland
- blocking the Beta II receptor on the submucosal gland
- Blocking the cholinergic receptor on the submucosal gland
4.Organophosphate poisoning is caused by:
- Increasing the action of the acetylcholinesterase
- Inhibition of the acetylcholinesterase
- Causing the acetylcholine to rise because it is not being broken down
- b and c
5.A patient can die from organophosphate poisoning or from an overdose of parasympathetic neurotransmitter due to:
- Rapid HR
- Slowed HR
- Skeletal muscle paralysis
6.A person who is getting intubated might get systemic atropine:
- to raise the HR to minimize the effect of vagal reflex bradycardia
- drop the HR to minimize the effect of vagal reflex bradycardia
7.During CPR, a patient might get systemic atropine to:
- Treat asystole
- Treat pulseless electrical activity
- Both of these
8.Inhaled cholinergic antagonists are indicated for maintenance bronchodilation, to treat wheezing associated with:
- COPD
- chronic bronchitis
- emphysema
- Croup
- All of these
- All but d
9.Would an acutely wheezing patient do better with Albuterol MDI for rescue bronchodilation or with inhalation of Atrovent MDI?
- Albuterol MDI
- Atrovent MDI
- Doesn’t matter both are excellent rescue bronchodilators
10.[Correction] A person who is going to have surgery might get systemic atropine to:
- Minimize reflex bradycardia during intubation
- Minimize glandular secretions during surgery
- Both
11.Side effects of systemic atropine include:
- dry mouth
- blurred vision
- tachycardia at moderate doses
- all of these
12.Side effects of systemic atropine include:
- Increased urination
- Urinary retention
- Complication of glaucoma by changing the shape of the iris
- Both b and c
13.Persons with sensitivities to soya lecithin should:
- Get a lot of systemic atropine
- Should avoid systemic atropine
14.Persons with prostatic hypertrophy can suffer – with systemic atropine.
- Increased urination
- Urinary retention
- Increased ocular blood pressure
15.The brand name for ipratropium bromide is:
- Atrovent®
- Breathaire®
- Spiriva®
16.The brand name for Tiotropium Bromide is:
- Atrovent®
- Breathaire®
- Spiriva®
17.The indication for Tiotropium Bromide is:
- prevent bedwetting
- maintenance for COPD, chronic bronchitis and emphysema
- rescue drug for COPD, chronic bronchitis & emphysema
- both a and c
18.Why is ipratropium bromide considered to be a safer inhaled drug than inhaled atropine?
- It has less effect on the Beta I receptor on the myocardium
- It has poor absorption at the tissue level so less gets into the blood stream
- Both of these
19.The usual dose of ipratropium bromide is:
- 500 micrograms in 2.5 ml sterile saline
- 2.5 mg in 2.5 ml sterile saline
- One inhalation by DPI Q day
20.The usual dose of Tiotropium Bromide is:
- 500 micrograms in 2.5 ml sterile saline
- 2.5 mg in 2.5 ml sterile saline
- One inhalation by DPI Q day
21.Combivent MDI contains these two drugs:
- Albuterol & ipratropium bromide
- Albuterol racemic epinephrine
- ipratropium bromide & salmeterol
- the same drugs that are found in Duoneb SVN unit dose
- a and d
- c and d
22.Combivent MDI is contraindicated in those persons with:
- Peanut allergy
- Soy food allergies
- Both a and b
23.The usual dose of Combivent MDI is:
- 2 puffs BID
- 2 puffs TID
- 2 puff QID
24.T/F The xanthine family of bronchodilators are oral and IV drugs.
25.T/F Theophylline is the only bronchodilator that increases the effectiveness of the diaphragm.
26.T/F The xanthine family of bronchodilators work by blocking the cholinergic receptors on the bronchial smooth muscle.
27.The aminophyline/theophylline works by:
- Inhibits phosphodiesterase that breaks down C-AMP
- Blocks adenosine receptors that cause bronchospasm
- Releases endogenous catecholamines
- inhibition of Ca uptake
- antagonist toward prostaglandin E2 & prostaglandin F2α
- all of these
28.T/F The xanthine family of bronchodilators are in the same family as caffeine and chocolate.
29.T/F Aminophyline and theophylline will raise the ventilatory drive.
30.T/F Aminophyline and theophylline differ mainly by differences in route of administration.
31.The therapeutic serum level of theophylline for bronchodilation associated with asthma is:
- 5 microns
- 5-15 micrograms
- 10 to 12 micrograms
- +20 micrograms
32.The therapeutic serum level of theophylline for bronchodilation associated with COPD is:
- 5 microns
- 5-15 micrograms
- 10 to 12 micrograms
- +20 micrograms
33.The therapeutic serum level of theophylline for treatment of apnea of prematurity is:
- 5 microns
- 5-15 micrograms
- 10 to 12 micrograms
- +20 micrograms
34.Side effects of aminophylline include:
- Tachycardia, hypotension & cardiac arrhythmias
- convulsions and seizures
- nausea, vomiting, cramps, diarrhea
- all of these
35.Drug interactions with aminophylline that result in decreasing the available amount of the drug include:
- Nicotine
- Marijuana
- Eating charcoal-grilledfoods
- TB antibiotics
- All of these
36.Phenobarbital is an excellent drug to give to a patient with an aminophylline overdose because:
- Phenobarbital treats the seizures & convulsions associated with this drug
- Phenobarbital decreases the amount of aminophylline in the body
- Both
37.Taking activated charcoal:
- Can act as an antidote to aminophylline
- Decreases the serum level of aminophylline
- Increases the serum level of aminophylline
- A and b
- A and c
38.Magnesium Sulfate:
- Is given by inhalation
- Is given by IV
- Relaxes smooth muscles in both labor contractions and asthma
- A and c
- B and c