UK RENAL REGISTRY
WorkProposal form
The information supplied in this form will be used by the UK Renal Registry (UKRR) and the UKRR Study Group members to determine whether to proceed with the proposed analysis and to prioritise the work if approved. In assessing the proposal the following criteria will be key:
- originality
- feasibility of addressing the question
- quality of available data
- plan of analysis
- likely importance to patients and the NHS
- cost
There are three possible levels of UKRR support:
- None – The UKRR sends you an anonymised dataset and you do all the analyses and write up yourselves (with no input/co-authorship from the UKRR). In this case you would be required to include the UKRR’s official disclaimer and acknowledgement in any publication. Due to the complex nature of the UKRR datasets we generally prefer applications at level 2 to those at level 1.
- Some – The UKRR sends you an anonymised dataset and you do most of the analyses locally but with some support with statistics/interpretation from the UKRR (i.e. co-author that approves final paper).
- Full – The UKRR does most of the analysis and someone locally writes up the paper (i.e. at least 2x UKRR co-authors, one statistician and one clinician).
For level 3 requests this form will be filled in by the UKRR – please contact us for informal discussions about the project to begin with ().
For level 1 or 2 requests, if possible, the form should be completed electronically and emailed to but please contact us if you would like to have an informal discussion about your proposed project before completing the form - for example, to check whether we have the necessary data items available.
Proposals will be sent out for peer review. They will also be circulated to the relevant UKRR Study Group(s) for discussion, a summary of decisions will be included with the agenda for each Patient Council meeting and, for accepted proposals, the lay summary will be made available on the UKRR website.
UK RENAL REGISTRY
Work Proposal form
(UKRR use) / Originator name: / Submitted date:
UKRR contact:
(UKRR use) / Address: / Telephone number:
Email address:
Level of UKRR input (1,2,or3: see above)
Title:
Lay summary:
(Max 500 words. Note: This will be made available on the UKRR website once approved)
How would this work benefit patients:
Background and justification for the study:
(To include the importance of the issue, a list of related existing work by other researchers and the UKRR)
Aims and objectives:
(Include relevant standards)
Additional data sources beyond the UKRR:
(List other data sources required for the analysis)
Funding:
(Provide detail if external funding is available).
Methodology
1. Dataset:(Including list of data items, inclusion and exclusion criteria).
2. Outcomes:
(Which, measured when?)
2.1 Primary:
2.2 Secondary:
3. Key exposure variables:
4. Key confounders:
5. How will missing data be dealt with?
(Especially ethnicity, comorbidity, date of referral)
6. Plan of statistical analysis:
(To include justification of the sample size, key analyses and method, if multivariate modelling how to check assumptions, adjustments for confounders, checking for interactions, sensitivity analysis, sub groups).
7. Statistical expertise
7.1. List all individuals who will be working with you on the analysis.
7.2. Indicate who will be (a) doing the statistical analysis and (b) supervising the statistical analysis
Information Governance
1. If you want to receive a dataset from us: Length of time you will hold the anonymised dataset before securely destroying.(In years)
2. For linkages:
If your proposal involves data linkage with data that you already hold then please send us the Patient Information Sheet and the Consent Form from your study (so that we can check that it is permissible for us to receive and link to your data).
3. For research:
If your proposal is research then we need it to have Research Ethics Committee (REC) approval and local R&D office sign-off. Please send us a letter from the REC and a copy of the local R&D office approval.
Note: There is a tool on the HRA website which can be used to define what is research -
New work?
Related work requests:
(UKRR use)
Estimated time allocation?
Decision and reason:
(UKRR use)
Originator informed:
(UKRR use)
UK Renal Registry work proposal form (version 2.0, Oct 2015)Page 1 of 6