"The Pharmacogenetics of Alcohol Dependence Treatment"

February 27th 2014

9:00-10:00

Class of 62 Auditorium, John Morgan Building

Henry Kranzler, MD

Professor, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania

Target Audience

This program has been designed for departmental/institutional faculty, fellows, residents, medical students, other health science students, nurses, allied health professional, and community physicians in the medical specialties of internal medicine, infectious disease, gastroenterology, cardiology, endocrinology, obstetrics and gynecology, nephrology, community health and prevention, oncology, critical care, pulmonary medicine, and cancer epidemiology.

Educational Objectives

After completing this activity, participants should be able to:

·  Better interpret results of studies in determining practice patterns bias

·  Implement strategies learned to improve patient adherence

·  Use new diagnostic and therapeutic techniques in their practice setting

Accreditation

The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgement of Commercial Support*

NONE

For more information, please contact

Cathy Mulvaney

215-573-4866

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Disclosure of Relevant Financial Relationships and Unapproved Uses of Products

It is policy at the Perelman School of Medicine at the University of Pennsylvania for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provides products or services that may be relevant to the content of this continuing medical education activity. For this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.

The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations.

The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania, Mila Kostic, Director of CME and the peer reviewer Zalman Agus, MD, Associate Dean for CME, have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity.

The following individuals have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity:

Planning Committee Member Name

Douglas Wiebe, PhD / Jimbo Chen, PhD / Marcella Devoto, PhD
Rui Feng, PhD / Scott Halpern, MD, PhD, MBE / Steven Kawut, MD, MS
Michael Levy, PhD / Mingyao Li, PhD / Mary Putt, PhD, ScH
Ebbing Lautenbach, MD, MPH, MSCE / KAthryn Schmitz, PhD, MPG

Presenter Name

The following individuals have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity.

Planning Committee Member Name Name of Commercial Interest Relationship

Robert Gross, MD, MSCE Abbott Laboratories, Bristol Myers Squibb Research Support

John Kempen, MD, PhD Clearsite, Lan&Fite, LuxBiosciences, Xoma Consultant

Eyegate PI

David Margolis, MD, PhD Centocor, Celleration, Macrocure DSMB

Kerecus Stock/Stipend

Peter Reese, MD, MSCE CVS Caremark Research Support

Merck Research Support

Presenter Name Name of Commercial Interest Relationship

Henry Kranzler, MD Alkermes, Lilly, Roche, Lundbeck, Pfizer Scientific Advisory Brd

Alkermes Safety Monitoring Brd & Consultant

Abbvie, Lilly Lundbeck, Pfizer Member of Alcohol Clinical Trials Initiat

Relevant Financial Relationships: Financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected

Disclosure of Unapproved Uses of Products

Presenter name Product Investigational and/or Off-label Use

Henry Kranzler / Ondansetron & Topiramate / Alcohol Dependence Treatment