“The Art of Bacterial Warfare”, by B. Brett Finlay, Scientific American, February 2010, p. 57:
Most bacteria are well-behaved companions. Indeed, if you are ever feeling lonely, remember that the trillions of microbes living in and on the average human body outnumber the human cells by a ratio of 10 to one. Of all the tens of thousands of known bacterial species, only about 100 are renegades that break the rules of peaceful coexistence and make us sick.
Collectively, those pathogens can cause a lot of trouble. Infectious diseases are the second leading cause of death worldwide, and bacteria are well represented among the killers. Tuberculosis alone takes nearly two million lives every year, and Yersinia pestis, infamous for causing bubonic plague, killed approximately one third of Europe’s population in the 14th century. Investigators have made considerable progress over the past 100 years in taming some species with antibiotics, but the harmful bacteria have also found ways to resist many of those drugs. It is an arms race that humans have been losing of late, in part because we have not understood our enemy very well.
Historically, microbiologists sought to learn how bacteria cause disease by growing them in a nourishing broth, then isolating molecules from the bugs’ exterior or extracting their secretions from the medium, and examining the effects of those substances on human cells and animals.
“Change We Can Believe In”, by Fareed Zakaria, Newsweek, February 1, 2010, p. 24:
How bad do things look for Barack Obama? Some historical perspective is useful. His approval ratings after one year in office are about the same as Ronald Reagan’s or Jimmy Carter’s and, in fact, are a bit higher than Bill Clinton’s. The Bushes fared better than all three of them, but for unusual reasons: 41 because he presided over the collapse of the Soviet Union in his first year in office, and 43 because the nation rallied around him after 9/11. As the economy improves, Obama’s numbers will surely rebound somewhat.
Still, last week’s special election in Massachusetts is a sign that Obama has a big problem. The public has clearly registered a protest vote against him, congressional Democrats, and their signature policy proposal: the health-care bill. The size of the swing, the issues raised during the campaign and in exit polls, and the migration of independents all suggest that Obama is confronting not just generalized anger but dissatisfaction with the course that the ruling party has taken. How he responds will shape the rest of his term.
A great debate has begun on the nature of that response. My own advice would be simple: Barack Obama needs to act like a president, especially the president he campaigned to become.
One Hundred Years of Solitude, by Gabriel Garcia Marquez (English translation) Harper Perennial 1991 New York. p. 1.
Many years later, as he faced the firing squad, Colonel Aureliano Buendía was to remember that distant afternoon when his father took him to discover ice. At that time Macondo was a village of twenty adobe houses, built on the bank of a river of clear water that ran along a bed of polished stones, which were white and enormous, like prehistoric eggs. The world was so recent that many things lacked names, and in order to indicate them it was necessary to point. Every year during the month of March a family of ragged gypsies would set up their tents near the village, and with a great uproar of pipes and kettledrums they would display new inventions. First they brought the magnet. A heavy gypsy with an untamed beard and sparrow hands, who introduced himself as Melquíades, put on a bold public demonstration of what he himself called the eighth wonder of the learned alchemists of Macedonia. He went from house to house dragging two metal ingots and everybody was amazed to see pots, pans, tongs, and braziers tumble down from their places and beams creak from the desperation of nails and screws trying to emerge, and even objects that had been lost for a long time appeared from where they had been searched for most and went dragging along in turbulent confusion behind Melquíades’ magical irons.