Type / Tissue: cell type (cell lines) / Ref
Adipose / Adipose / [1, 2]
Bladder / Bladder / [1, 2]
Blood / Dendritic / [3–8]
Eosinophils / [5, 6]
Granulocyte / [9]
Leukocyte (HL-60, F-36P) / [3, 10–12]
Lymphocyte: natural killer (NK), CD8+, CD4+ (Jurkat, CLL, LCL) / [1–3, 8, 10, 13–19]
Macrophage (dU937) / [1, 2, 10, 20–23]
Mast / [24, 25]
Megakaryocyte (CMK-86, M-07e, UT7-Epo) / [1, 2]
Monocyte / [1–3, 8, 14–17, 22, 26–29]
Monocyte-derived dendritic / [10, 30, 31]
Neutrophils / [1, 2, 14–17, 32]
Peripheral blood mononuclear / [18]
Platelet / [1, 2, 14–17, 32–35]
Bone / cartilage / Bone / [1, 2]
Cartilage / [1, 2]
Chondrocyte (C2OA4, HAC60) / [1, 2]
Osteosarcoma (HOS, MG63, SaOS-2) / [1, 2, 36, 37]
Brain / Astrocyte (1321N1,CCF-STTG1) / [1–3]
Brain / [1, 2, 38]
Glia (Hs-683, C13, H4) / [1, 2]
Neuroblastoma (IMR32-, IMR32+, SH-SY-5Y-, SH-SY-5Y+) / [1, 2]
Development / Embryo (HEK-293) / [1, 2, 38–40]
Embryo from Xenopus / [41]
Embryo lung fibroblast (MRC-9) / [1, 2]
Placenta / [1, 2, 42–44]
Stem cell: CD34+, mesenchymal / [14–17, 45]
Teratoma (NT-2) / [1, 2]
Endocrine / Thyrocyte / [46]
Endothelium / Endothelium: ± idiopathic pulmonary arterial hypertension, umbilical vein / aortic, cerebral (hCMEC-D3), coronary artery (HCAEC) / [1, 2, 14–17, 47–52]
Epithelium / Epithelium: (Calu-6, HeLa), airway (NuLi-1, CuFi-1), bladder, breast (MDA-MB-468), colon (Caco-2, HCT8), corneal, middle ear / nose, pancreas (PANC-1, CFPAC-1, CAPAN-1), prostate (DU145, PC-3, PNT-2, LNCaP), bile duct (H69, Mz-ChA-1) / [1, 2, 23, 33–35, 38, 40, 53–60]
Epithelium: (MDCK-D1) and pancreatic duct from dog / [61–64]
Eye / Trabecular meshwork (HTM-3) / [65]
Heart / Heart / [1, 2, 66, 67]
Intestine / Intestine, enterochromaffin cell (BON) / [1, 2, 68]
Joint / Synoviocyte / [69]
Kidney / Fibroblast (COS-1) from African green monkey / [1, 2]
Kidney including cortex (HK-2) / [1, 2, 38]
Liver / Liver including hepatocyte (HepG2, Chang, WRL68) / [1, 2, 38]
Lung / Lung / [1, 2]
Muscle / Muscle: skeletal, smooth aortic (AOSMC+), coronary artery (HCASMC) / [1, 2, 14–17, 38, 70]
Muscle smooth from guinea pig / [71]
Pancreas / Pancreas / [1, 2, 44]
Prostate / Prostate / [1, 2]
Skin / Keratinocyte (HaCaT) / [26, 72–74]
Melanocyte (LB23) / [10]
Spleen / Spleen / [1, 2, 38]
Stomach / Stomach / [1, 2]
Testes / Testes / [38]
Table S5: Tissue, cell types and cell lines fulfilling expression criteria as described in the text. Articles reporting detection of the P2Y11 receptor and not fulfilling expression criteria or where PCR primer sequences were not available are:[14, 29, 51, 52, 57, 58, 71, 75–111].
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