Table S3A: Cluster Specific Lipid Category Enrichment

Table S3A: Cluster specific lipid category enrichment

Cluster 1 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 3.26E-02 / 10 / 0.019
Cluster 2 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 3.87E-04 / 61 / 0.116
sphingolipids / 1.21E-02 / 12 / 0.158
glycerolipids / 9.83E-01 / 6 / 0.041
fatty acyls / 1.00E+00 / 3 / 0.014
prenol lipids / 1.00E+00 / 2 / 0.012
category_unclear / 1.00E+00 / 1 / 0.005
sterol lipids / 9.92E-01 / 1 / 0.014
Cluster 3 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 1.81E-06 / 69 / 0.132
sphingolipids / 2.52E-03 / 14 / 0.184
glycerolipids / 9.89E-01 / 6 / 0.041
sterol lipids / 8.25E-01 / 4 / 0.055
prenol lipids / 1.00E+00 / 3 / 0.019
fatty acyls / 1.00E+00 / 3 / 0.014
Cluster 4 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 8.38E-03 / 26 / 0.050
glycerolipids / 4.51E-01 / 5 / 0.034
fatty acyls / 9.11E-01 / 4 / 0.019
sphingolipids / 3.07E-01 / 3 / 0.039
saccharolipids / 2.29E-03 / 2 / 0.250
polyketides / 6.15E-01 / 1 / 0.018
category_unclear / 9.98E-01 / 1 / 0.005
sterol lipids / 7.67E-01 / 1 / 0.014
Cluster 5 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 1.32E-01 / 2 / 0.004
Cluster 6 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 1.77E-04 / 30 / 0.057
glycerolipids / 8.24E-01 / 3 / 0.021
fatty acyls / 9.92E-01 / 2 / 0.010
sphingolipids / 5.61E-01 / 2 / 0.026
prenol lipids / 9.90E-01 / 1 / 0.006
sterol lipids / 7.80E-01 / 1 / 0.014
Cluster 7 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 1.40E-02 / 91 / 0.174
glycerolipids / 8.63E-01 / 17 / 0.117
fatty acyls / 1.00E+00 / 15 / 0.072
prenol lipids / 1.00E+00 / 8 / 0.050
sphingolipids / 9.83E-01 / 5 / 0.066
sterol lipids / 9.92E-01 / 4 / 0.055
Cluster 8 / p-value / # of IDs / ratio: sign/total IDs
glycerophospholipids / 9.66E-03 / 21 / 0.040
prenol lipids / 5.17E-01 / 4 / 0.025
glycerolipids / 4.19E-01 / 4 / 0.028
fatty acyls / 7.58E-01 / 4 / 0.019
sterol lipids / 3.59E-01 / 2 / 0.027
sphingolipids / 3.84E-01 / 2 / 0.026
category_unclear / 9.52E-01 / 2 / 0.010
polyketides / 4.84E-01 / 1 / 0.018

Table S3B: Cluster specific lipid class enrichment

Cluster 1 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoethanolamines / 1.80E-02 / 7 / 0.025
glycerophosphocholines / 7.27E-02 / 6 / 0.020
class_unclear / 8.27E-01 / 3 / 0.008
glycerophosphoinositols / 3.99E-03 / 3 / 0.058
glycerophosphates / 1.29E-02 / 3 / 0.042
glycerophosphoserines / 2.18E-01 / 2 / 0.017
Cluster 2 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoserines / 4.42E-08 / 28 / 0.233
neutral glycosphingolipids / 4.30E-03 / 6 / 0.240
glycerophosphates / 1.94E-02 / 11 / 0.153
phosphosphingolipids / 2.12E-02 / 6 / 0.182
glycerophosphoethanolamines / 1.36E-01 / 29 / 0.102
glycerophosphoinositols / 1.68E-01 / 6 / 0.115
glycerophosphocholines / 2.69E-01 / 28 / 0.095
class_unclear / 1.00E+00 / 6 / 0.016
isoprenoids / 1.00E+00 / 2 / 0.015
diradylglycerols / 9.10E-01 / 2 / 0.034
fatty acids and conjugates / 9.64E-01 / 2 / 0.028
glycerophosphoglycerols / 7.36E-01 / 2 / 0.048
ceramides / 1.19E-01 / 2 / 0.143
glycosyldiradylglycerols / 1.80E-02 / 2 / 0.286
monoradylglycerols / 7.93E-01 / 1 / 0.031
fatty esters / 5.68E-01 / 1 / 0.048
bile acids and derivatives / 5.68E-01 / 1 / 0.048
sterols / 6.43E-01 / 1 / 0.042
secosteroids / 1.21E-01 / 1 / 0.143
fatty acyl glycosides / 7.74E-03 / 1 / 0.500
oxidized glycerophospholipids / 7.44E-01 / 1 / 0.034
triradylglycerols / 8.85E-01 / 1 / 0.025
Cluster 3 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoserines / 2.75E-10 / 32 / 0.267
glycerophosphates / 8.04E-06 / 18 / 0.250
oxidized glycerophospholipids / 2.01E-05 / 10 / 0.345
glycerophosphoethanolamines / 2.93E-05 / 43 / 0.152
phosphosphingolipids / 8.19E-05 / 10 / 0.303
glycerophosphoglycerols / 8.89E-04 / 10 / 0.238
neutral glycosphingolipids / 2.20E-02 / 5 / 0.200
glycerophosphocholines / 4.19E-02 / 34 / 0.116
glycerophosphoinositols / 9.75E-02 / 7 / 0.135
diradylglycerols / 6.52E-01 / 4 / 0.068
class_unclear / 1.00E+00 / 11 / 0.029
sterols / 1.74E-01 / 3 / 0.125
triradylglycerols / 7.33E-01 / 2 / 0.050
isoprenoids / 1.00E+00 / 1 / 0.008
fatty acids and conjugates / 9.94E-01 / 1 / 0.014
steroids / 6.89E-01 / 1 / 0.040
quinones and hydroquinones / 5.65E-01 / 1 / 0.050
fatty acyl glycosides / 8.44E-03 / 1 / 0.500
other glycerophospholipids / 8.44E-03 / 1 / 0.500
hopanoids / 0.00E+00 / 1 / 1.000
glycerophosphonoethanolamines / 0.00E+00 / 1 / 1.000
Cluster 4 / p-value / # of IDs / ratio: sign/total IDs
oxidized glycerophospholipids / 4.58E-05 / 6 / 0.207
glycerophosphates / 1.33E-02 / 6 / 0.083
glycerophosphoethanolamines / 3.43E-02 / 15 / 0.053
glycerophosphoinositols / 3.82E-02 / 4 / 0.077
glycerophosphocholines / 4.81E-02 / 15 / 0.051
glycerophosphoserines / 1.44E-01 / 6 / 0.050
class_unclear / 9.97E-01 / 6 / 0.016
fatty acids and conjugates / 2.72E-01 / 3 / 0.042
glycerophosphoglycerols / 6.46E-02 / 3 / 0.071
neutral glycosphingolipids / 1.15E-02 / 3 / 0.120
glycosyldiradylglycerols / 5.13E-05 / 3 / 0.429
diradylglycerols / 3.74E-01 / 2 / 0.034
acyltrehaloses / 0.00E+00 / 2 / 1.000
eicosanoids / 4.96E-02 / 1 / 0.100
bile acids and derivatives / 1.80E-01 / 1 / 0.048
glycosylglycerophospholipids / 1.24E-02 / 1 / 0.200
Cluster 5 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoethanolamines / 2.06E-02 / 2 / 0.007
glycerophosphocholines / 2.32E-02 / 2 / 0.007
glycerophosphoserines / 1.55E-03 / 2 / 0.017
glycerophosphates / 1.38E-02 / 1 / 0.014
Cluster 6 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoserines / 4.50E-09 / 18 / 0.150
glycerophosphoinositols / 4.22E-02 / 4 / 0.077
glycerophosphates / 4.89E-02 / 5 / 0.069
glycerophosphocholines / 6.09E-02 / 15 / 0.051
glycerophosphoethanolamines / 8.66E-02 / 14 / 0.049
diradylglycerols / 1.80E-01 / 3 / 0.051
class_unclear / 1.00E+00 / 2 / 0.005
phosphosphingolipids / 1.25E-01 / 2 / 0.061
isoprenoids / 9.68E-01 / 1 / 0.008
other glycerolipids / 4.26E-02 / 1 / 0.111
bile acids and derivatives / 1.87E-01 / 1 / 0.048
sterols / 2.30E-01 / 1 / 0.042
secosteroids / 2.61E-02 / 1 / 0.143
glycosylglycerophospholipids / 1.30E-02 / 1 / 0.200
hydrocarbons / 0.00E+00 / 1 / 1.000
Cluster 7 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphoinositols / 6.69E-03 / 14 / 0.269
glycerophosphocholines / 1.65E-02 / 55 / 0.187
fatty esters / 8.20E-02 / 5 / 0.238
glycerophosphoethanolamines / 1.71E-01 / 47 / 0.166
glycerophosphoserines / 1.75E-01 / 21 / 0.175
glycerophosphoglycerols / 2.91E-01 / 7 / 0.167
monoradylglycerols / 3.48E-01 / 5 / 0.156
glycerophosphates / 3.99E-01 / 11 / 0.153
fatty acids and conjugates / 7.85E-01 / 8 / 0.111
diradylglycerols / 8.13E-01 / 6 / 0.102
isoprenoids / 1.00E+00 / 6 / 0.046
class_unclear / 1.00E+00 / 25 / 0.065
eicosanoids / 4.98E-02 / 3 / 0.300
neutral glycosphingolipids / 5.34E-01 / 3 / 0.120
secosteroids / 1.20E-02 / 3 / 0.429
triradylglycerols / 8.77E-01 / 3 / 0.075
fatty amides / 6.35E-01 / 2 / 0.095
other glycerolipids / 1.41E-01 / 2 / 0.222
quinones and hydroquinones / 6.00E-01 / 2 / 0.100
ceramides / 6.48E-01 / 1 / 0.071
bile acids and derivatives / 8.50E-01 / 1 / 0.048
fatty aldehydes / 4.59E-01 / 1 / 0.100
sterols / 8.98E-01 / 1 / 0.042
steroids / 9.11E-01 / 1 / 0.040
other glycerophospholipids / 2.26E-02 / 1 / 0.500
glycosyldiradylglycerols / 2.85E-01 / 1 / 0.143
glycerophosphonocholines / 0.00E+00 / 1 / 1.000
sphingoid bases / 2.26E-02 / 1 / 0.500
fatty alcohols / 0.00E+00 / 1 / 1.000
oxygenated hydrocarbons / 0.00E+00 / 1 / 1.000
Cluster 8 / p-value / # of IDs / ratio: sign/total IDs
glycerophosphates / 1.06E-04 / 8 / 0.111
glycerophosphoethanolamines / 1.53E-04 / 17 / 0.060
glycerophosphocholines / 2.63E-04 / 17 / 0.058
class_unclear / 7.31E-01 / 9 / 0.024
isoprenoids / 5.38E-01 / 3 / 0.023
fatty acids and conjugates / 1.52E-01 / 3 / 0.042
diradylglycerols / 2.44E-01 / 2 / 0.034
sterols / 2.99E-02 / 2 / 0.083
quinones and hydroquinones / 1.82E-02 / 2 / 0.100
diterpenes / 4.13E-01 / 1 / 0.021
monoradylglycerols / 2.39E-01 / 1 / 0.031
fatty amides / 1.23E-01 / 1 / 0.048
glycerophosphoinositols / 4.54E-01 / 1 / 0.019
neutral glycosphingolipids / 1.63E-01 / 1 / 0.040
oxo fatty acids / 3.20E-02 / 1 / 0.100
glycerophosphoserines / 8.83E-01 / 1 / 0.008
glycosyldiradylglycerols / 1.58E-02 / 1 / 0.143
sphingoid bases / 8.22E-04 / 1 / 0.500

Table S3C: Cluster specific lipid subclass enrichment

Cluster 1 / p-value / # of IDs / ratio: sign/total IDs
diacylglycerophosphocholines / 4.95E-04 / 6 / 0.049
diacylglycerophosphoethanolamines / 2.66E-03 / 5 / 0.043
hmdb_missing / 8.22E-01 / 7 / 0.010
diacylglycerophosphoinositols / 4.20E-04 / 3 / 0.103
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 7.15E-03 / 3 / 0.049
diacylglycerophosphates / 1.79E-02 / 2 / 0.047
1-alkyl,2-acylglycerophosphoethanolamines / 4.52E-02 / 2 / 0.033
1-(1z-alkenyl),2-acylglycerophosphoserines / 9.56E-02 / 1 / 0.026
1-alkyl,2-acylglycerophosphoserines / 1.31E-01 / 1 / 0.021
1-alkyl,2-acylglycerophosphocholines / 1.84E-01 / 1 / 0.017
1-(1z-alkenyl),2-acylglycerophosphates / 2.84E-02 / 1 / 0.050
1-alkyl,2-acylglycerophosphates / 1.43E-02 / 1 / 0.071
Cluster 2 / p-value / # of IDs / ratio: sign/total IDs
diacylglycerophosphoserines / 2.91E-11 / 21 / 0.396
diacylglycerophosphoethanolamines / 2.24E-05 / 23 / 0.197
diacylglycerophosphocholines / 1.69E-04 / 22 / 0.179
ceramide phosphocholines (sphingomyelins) / 1.99E-04 / 6 / 0.375
simple glc series / 3.15E-04 / 6 / 0.353
diacylglycerophosphates / 7.57E-04 / 10 / 0.233
diacylglycerophosphoinositols / 1.04E-02 / 6 / 0.207
1-alkyl,2-acylglycerophosphoserines / 1.13E-01 / 6 / 0.128
1-(1z-alkenyl),2-acylglycerophosphoserines / 1.22E-01 / 5 / 0.128
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 6.43E-01 / 4 / 0.066
hmdb_missing / 1.00E+00 / 30 / 0.045
1-(1z-alkenyl),2-acylglycerophosphocholines / 7.49E-01 / 3 / 0.054
ceramide 1-phosphates / 0.00E+00 / 2 / 1.000
dialkylglycerophosphocholines / 1.10E-02 / 2 / 0.333
branched fatty acids / 1.10E-02 / 2 / 0.333
glycosyldiacylglycerols / 1.80E-02 / 2 / 0.286
diacylglycerophosphoglycerols / 1.85E-01 / 2 / 0.118
diacylglycerols / 2.08E-01 / 2 / 0.111
1-alkyl,2-acylglycerophosphocholines / 9.03E-01 / 2 / 0.034
1-alkyl,2-acylglycerophosphoethanolamines / 9.21E-01 / 2 / 0.033
vitamin d4 and derivatives / 0.00E+00 / 1 / 1.000
spirostanols and derivatives / 0.00E+00 / 1 / 1.000
furospirostanols and derivatives / 0.00E+00 / 1 / 1.000
fatty acyl glycosides of mono- and disaccharides / 7.74E-03 / 1 / 0.500
ceramide phosphoethanolamines / 7.74E-03 / 1 / 0.500
c27 bile acids, alcohols, and derivatives / 7.74E-03 / 1 / 0.500
1-acyl,2-alkylglycerophosphocholines / 7.74E-03 / 1 / 0.500
c15 isoprenoids (sesquiterpenes) / 7.74E-03 / 1 / 0.500
cholesterol and derivatives / 2.19E-02 / 1 / 0.333
1-acyl,2-alkylglycerophosphoethanolamines / 2.19E-02 / 1 / 0.333
wax monoesters / 2.19E-02 / 1 / 0.333
lactones / 2.19E-02 / 1 / 0.333
monoacylglycerophosphocholines / 2.19E-02 / 1 / 0.333
1z-alkenylglycerophosphoethanolamines / 2.19E-02 / 1 / 0.333
unsaturated fatty acids / 4.13E-02 / 1 / 0.250
vitamin d3 and derivatives / 6.48E-02 / 1 / 0.200
tetraterpenes / 6.48E-02 / 1 / 0.200
monoacylglycerophosphoethanolamines / 6.48E-02 / 1 / 0.200
monoacylglycerols / 9.18E-02 / 1 / 0.167
triacylglycerols / 9.18E-02 / 1 / 0.167
oxidized glycerophosphoethanolamines / 2.53E-01 / 1 / 0.091
1-(1z-alkenyl),2-acylglycerophosphates / 5.41E-01 / 1 / 0.050
diacylglycerols / 9.55E-01 / 1 / 0.019
Cluster 3 / p-value / # of IDs / ratio: sign/total IDs
dialkylglycerophosphoglycerols / 0.00E+00 / 4 / 1.000
1-(1z-alkenyl),2-acylglycerophosphoserines / 5.82E-11 / 18 / 0.462
diacylglycerophosphoethanolamines / 1.27E-10 / 32 / 0.274
diacylglycerophosphocholines / 2.85E-09 / 31 / 0.252
1-alkyl,2-acylglycerophosphoserines / 2.51E-08 / 17 / 0.362
diacylglycerophosphates / 3.72E-08 / 16 / 0.372
ceramide phosphocholines (sphingomyelins) / 2.25E-06 / 8 / 0.500
oxidized glycerophosphoethanolamines / 1.68E-04 / 5 / 0.455
diacylglycerophosphoglycerols / 4.14E-04 / 6 / 0.353
diacylglycerophosphoserines / 5.87E-04 / 12 / 0.226
simple glc series / 2.83E-03 / 5 / 0.294
diacylglycerophosphoinositols / 3.30E-03 / 7 / 0.241
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 7.22E-03 / 11 / 0.180
diacylglycerols / 1.96E-02 / 4 / 0.222
1-alkyl,2-acylglycerophosphoethanolamines / 4.65E-02 / 9 / 0.148
1-(1z-alkenyl),2-acylglycerophosphocholines / 6.04E-01 / 4 / 0.071
hmdb_missing / 1.00E+00 / 40 / 0.060
oxidized glycerophosphocholines / 0.00E+00 / 3 / 1.000
steryl esters / 3.18E-04 / 3 / 0.600
sphingomyelins / 1.05E-01 / 3 / 0.150
1-acyl,2-alkylglycerophosphoethanolamines / 7.64E-04 / 2 / 0.667
monoacylglycerophosphoethanolamines / 6.65E-03 / 2 / 0.400
triacylglycerols / 1.24E-02 / 2 / 0.333
3.03E-02 / 2 / 0.250
1-alkyl,2-acylglycerophosphates / 1.32E-01 / 2 / 0.143
cardiolipins / 1.54E-01 / 2 / 0.133
1-(1z-alkenyl),2-acylglycerophosphates / 2.79E-01 / 2 / 0.100
diacylglycerols / 8.77E-01 / 2 / 0.038
1-alkyl,2-acylglycerophosphocholines / 9.19E-01 / 2 / 0.034
diacylglycerophosphonoethanolamines / 0.00E+00 / 1 / 1.000
dialkylglycerophosphoethanolamines / 0.00E+00 / 1 / 1.000
c19 steroids (androgens) and derivatives / 0.00E+00 / 1 / 1.000
c20 isoprenoids (diterpenes) / 0.00E+00 / 1 / 1.000
fatty acyl glycosides of mono- and disaccharides / 8.44E-03 / 1 / 0.500
ceramide phosphoethanolamines / 8.44E-03 / 1 / 0.500
ergosterols and c24-methyl derivatives / 8.44E-03 / 1 / 0.500
carbocyclic fatty acids / 8.44E-03 / 1 / 0.500
1-acyl,2-alkylglycerols / 2.38E-02 / 1 / 0.333
ubiquinones / 4.47E-02 / 1 / 0.250
unsaturated fatty acids / 4.47E-02 / 1 / 0.250
monoacylglycerophosphomonoradylglycerols / 9.90E-02 / 1 / 0.167
dialkylglycerophosphocholines / 9.90E-02 / 1 / 0.167
branched fatty acids / 9.90E-02 / 1 / 0.167
Cluster 4 / p-value / # of IDs / ratio: sign/total IDs
oxidized glycerophosphoethanolamines / 6.85E-07 / 5 / 0.455
diacylglycerophosphocholines / 8.99E-06 / 14 / 0.114
diacylglycerophosphoethanolamines / 2.58E-05 / 13 / 0.111
diacylglycerophosphates / 3.77E-03 / 5 / 0.116
1-alkyl,2-acylglycerophosphocholines / 5.72E-02 / 4 / 0.069
1-alkyl,2-acylglycerophosphoethanolamines / 6.85E-02 / 4 / 0.066
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 6.85E-02 / 4 / 0.066
hmdb_missing / 9.97E-01 / 16 / 0.024
diacylglycerophosphoglycerols / 2.67E-03 / 3 / 0.176
simple glc series / 2.67E-03 / 3 / 0.176
1-(1z-alkenyl),2-acylglycerophosphocholines / 1.47E-01 / 3 / 0.054
glycosyldiacylglycerols / 5.13E-05 / 3 / 0.429
diacylglycerols / 3.00E-01 / 2 / 0.038
diacylglycerophosphoinositols / 8.76E-02 / 2 / 0.069
1-(1z-alkenyl),2-acylglycerophosphoserines / 1.71E-01 / 2 / 0.051
1-alkyl,2-acylglycerophosphoserines / 2.49E-01 / 2 / 0.043
diacylglycerols / 2.58E-02 / 2 / 0.111
diacylglycerophosphoserines / 3.11E-01 / 2 / 0.038
mycolic acids / 0.00E+00 / 2 / 1.000
monoacylglycerophosphoinositols / 0.00E+00 / 2 / 1.000
monoacylglycerophosphomonoradylglycerols / 1.81E-02 / 1 / 0.167
bile acids, alcohols and derivatives / 6.94E-02 / 1 / 0.083
dicarboxylic acids / 1.81E-02 / 1 / 0.167
c24 bile acids, alcohols, and derivatives / 0.00E+00 / 1 / 1.000
1-(1z-alkenyl),2-acylglycerophosphates / 1.66E-01 / 1 / 0.050
diacylglycosylglycerophospholipids / 0.00E+00 / 1 / 1.000
cardiolipins / 1.03E-01 / 1 / 0.067
prostaglandins / 0.00E+00 / 1 / 1.000
Cluster 5 / p-value / # of IDs / ratio: sign/total IDs
1-(1z-alkenyl),2-acylglycerophosphoserines / 5.05E-05 / 2 / 0.051
1-alkyl,2-acylglycerophosphoserines / 8.96E-05 / 2 / 0.043
diacylglycerophosphoethanolamines / 1.44E-03 / 2 / 0.017
diacylglycerophosphocholines / 1.67E-03 / 2 / 0.016
diacylglycerophosphates / 4.99E-03 / 1 / 0.023
hmdb_missing / 7.21E-01 / 1 / 0.001
Cluster 6 / p-value / # of IDs / ratio: sign/total IDs
diacylglycerophosphoserines / 1.19E-08 / 12 / 0.226
diacylglycerophosphocholines / 6.55E-05 / 13 / 0.106
diacylglycerophosphoethanolamines / 1.72E-04 / 12 / 0.103
1-alkyl,2-acylglycerophosphoserines / 1.33E-03 / 6 / 0.128
diacylglycerophosphoinositols / 3.66E-03 / 4 / 0.138
diacylglycerophosphates / 4.32E-03 / 5 / 0.116
1-(1z-alkenyl),2-acylglycerophosphoserines / 1.34E-02 / 4 / 0.103
hmdb_missing / 1.00E+00 / 12 / 0.018
diacylglycerols / 1.29E-01 / 3 / 0.058
ceramide phosphocholines (sphingomyelins) / 2.00E-02 / 2 / 0.125
sphingomyelins / 3.67E-02 / 2 / 0.100
sesterterpenes / 1.33E-01 / 1 / 0.059
vitamin d3 and derivatives / 1.30E-02 / 1 / 0.200
cholesterols and derivatives / 3.39E-02 / 1 / 0.125
1-(1z-alkenyl),2-acylglycerophosphocholines / 6.39E-01 / 1 / 0.018
1-alkyl,2-acylglycerophosphoethanolamines / 6.87E-01 / 1 / 0.016
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 6.87E-01 / 1 / 0.016
cholesterol and derivatives / 4.10E-03 / 1 / 0.333
furostanols and derivatives / 0.00E+00 / 1 / 1.000
c27 bile acids, alcohols, and derivatives / 1.40E-03 / 1 / 0.500
sesterterpenes / 1.40E-03 / 1 / 0.500
1-acyl,2-alkylglycerols / 4.10E-03 / 1 / 0.333
1-alkyl,2-acylglycerols / 1.40E-03 / 1 / 0.500
glycosylglycerols / 8.01E-03 / 1 / 0.250
monoacylglycerophosphoethanolamines / 1.30E-02 / 1 / 0.200
monoacylglycerophosphocholines / 4.10E-03 / 1 / 0.333
Cluster 7 / p-value / # of IDs / ratio: sign/total IDs
1-alkyl,2-acylglycerophosphocholines / 2.28E-16 / 34 / 0.586
1-(1z-alkenyl),2-acylglycerophosphocholines / 5.31E-15 / 32 / 0.571
1-alkyl,2-acylglycerophosphoethanolamines / 9.77E-12 / 30 / 0.492
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 1.38E-08 / 26 / 0.426
1-(1z-alkenyl),2-acylglycerophosphoinositols / 2.27E-07 / 7 / 0.875
1-alkyl,2-acylglycerophosphoinositols / 2.27E-07 / 7 / 0.875
1-(1z-alkenyl),2-acylglycerophosphates / 2.17E-04 / 9 / 0.450
1-alkyl,2-acylglycerophosphates / 3.00E-04 / 7 / 0.500
monoacylglycerophosphomonoradylglycerols / 3.86E-04 / 4 / 0.667
dicarboxylic acids / 3.86E-04 / 4 / 0.667
monoacylglycerols / 3.86E-04 / 4 / 0.667
1-alkyl,2-acylglycerophosphoserines / 6.41E-03 / 13 / 0.277
diacylglycerophosphoglycerols / 7.94E-03 / 6 / 0.353
diacylglycerols / 4.12E-02 / 5 / 0.278
diacylglycerophosphoinositols / 5.71E-02 / 7 / 0.241
diacylglycerophosphocholines / 9.34E-02 / 23 / 0.187
diacylglycerophosphoethanolamines / 2.97E-01 / 19 / 0.162
1-(1z-alkenyl),2-acylglycerophosphoserines / 3.71E-01 / 6 / 0.154
monoacylglycerols / 4.81E-01 / 4 / 0.133
diacylglycerophosphoserines / 7.11E-01 / 6 / 0.113
diacylglycerols / 9.15E-01 / 4 / 0.077
hmdb_missing / 1.00E+00 / 52 / 0.077
monoalkylglycerophosphocholines / 0.00E+00 / 3 / 1.000
1z-alkenylglycerophosphocholines / 0.00E+00 / 3 / 1.000
vitamin d3 and derivatives / 2.20E-03 / 3 / 0.600
tetraterpenes / 2.20E-03 / 3 / 0.600
dialkylglycerophosphocholines / 5.82E-03 / 3 / 0.500
branched fatty acids / 5.82E-03 / 3 / 0.500
triacylglycerols / 5.82E-03 / 3 / 0.500
other hydroxyeicosapolyenoic acids / 3.37E-02 / 3 / 0.333
wax monoesters / 3.36E-03 / 2 / 0.667
lactones / 3.36E-03 / 2 / 0.667
1z-alkenylglycerophosphoethanolamines / 3.36E-03 / 2 / 0.667
ubiquinones / 1.20E-02 / 2 / 0.500
unsaturated fatty acids / 1.20E-02 / 2 / 0.500
acyl carnitines / 3.10E-01 / 2 / 0.154
simple glc series / 4.84E-01 / 2 / 0.118
diacylglycerophosphates / 9.69E-01 / 2 / 0.047
fatty acyl carnitines / 0.00E+00 / 1 / 1.000
diacylglycerophosphonocholines / 0.00E+00 / 1 / 1.000
dialkylglycerols / 0.00E+00 / 1 / 1.000
n-acylsphinganines (dihydroceramides) / 0.00E+00 / 1 / 1.000
n-acylsphingosines (ceramides) / 0.00E+00 / 1 / 1.000
cyano esters / 0.00E+00 / 1 / 1.000
calysterols and cyclopropylsidechain derivatives / 0.00E+00 / 1 / 1.000
hydroperoxy fatty acids / 0.00E+00 / 1 / 1.000
monoalkylglycerols / 0.00E+00 / 1 / 1.000
c23 bile acids, alcohols, and derivatives / 0.00E+00 / 1 / 1.000
sphinganines / 0.00E+00 / 1 / 1.000
primary amides / 0.00E+00 / 1 / 1.000
monoacylglycerophosphoglycerols / 0.00E+00 / 1 / 1.000
monoalkylglycerophosphoethanolamines / 0.00E+00 / 1 / 1.000
sesterterpenes / 2.26E-02 / 1 / 0.500
1-alkyl,2-acylglycerols / 2.26E-02 / 1 / 0.500
ergosterols and c24-methyl derivatives / 2.26E-02 / 1 / 0.500
other steroids and derivatives / 2.26E-02 / 1 / 0.500
hydroxy fatty acids / 2.26E-02 / 1 / 0.500
sphingoid base analogs / 2.26E-02 / 1 / 0.500
carbocyclic fatty acids / 2.26E-02 / 1 / 0.500
cholesterol and derivatives / 6.10E-02 / 1 / 0.333
1-acyl,2-alkylglycerols / 6.10E-02 / 1 / 0.333
glycosyldiacylglycerols / 2.85E-01 / 1 / 0.143
cholesterols and derivatives / 3.45E-01 / 1 / 0.125
endocannabinoids / 4.03E-01 / 1 / 0.111
n-acyl amines / 5.60E-01 / 1 / 0.083
sesterterpenes / 7.52E-01 / 1 / 0.059
unsaturated fatty acids / 8.98E-01 / 1 / 0.042
triacylglycerols / 9.78E-01 / 1 / 0.029
sesquiterpenes / 9.88E-01 / 1 / 0.026
monoterpenes / 9.94E-01 / 1 / 0.023
Cluster 8 / p-value / # of IDs / ratio: sign/total IDs
1-alkyl,2-acylglycerophosphocholines / 2.36E-12 / 14 / 0.241
1-(1z-alkenyl),2-acylglycerophosphocholines / 2.86E-11 / 13 / 0.232
1-alkyl,2-acylglycerophosphoethanolamines / 1.69E-09 / 12 / 0.197
1-(1z-alkenyl),2-acylglycerophosphoethanolamines / 1.69E-09 / 12 / 0.197
1-(1z-alkenyl),2-acylglycerophosphates / 5.13E-07 / 6 / 0.300
diacylglycerophosphocholines / 1.12E-05 / 12 / 0.098
1-alkyl,2-acylglycerophosphates / 2.49E-05 / 4 / 0.286
diacylglycerophosphoethanolamines / 3.95E-05 / 11 / 0.094
hmdb_missing / 7.91E-01 / 17 / 0.025
steryl esters / 2.15E-04 / 2 / 0.400
diacylglycerols / 1.36E-02 / 2 / 0.111
vitamin e / 0.00E+00 / 1 / 1.000
oxo fatty acids / 0.00E+00 / 1 / 1.000
1-acyl,2-alkylglycerophosphocholines / 8.22E-04 / 1 / 0.500
c15 isoprenoids (sesquiterpenes) / 8.22E-04 / 1 / 0.500
hydroxy fatty acids / 8.22E-04 / 1 / 0.500
sphingoid base analogs / 8.22E-04 / 1 / 0.500
ubiquinones / 4.76E-03 / 1 / 0.250
tetraterpenes / 7.78E-03 / 1 / 0.200
keto fatty acids / 1.15E-02 / 1 / 0.167
dicarboxylic acids / 1.15E-02 / 1 / 0.167
monoacylglycerols / 1.15E-02 / 1 / 0.167
dicarboxylic acids and derivatives / 1.58E-02 / 1 / 0.143
glycosyldiacylglycerols / 1.58E-02 / 1 / 0.143
1-(1z-alkenyl),2-acylglycerophosphoinositols / 2.06E-02 / 1 / 0.125
1-alkyl,2-acylglycerophosphoinositols / 2.06E-02 / 1 / 0.125
n-acyl amines / 4.52E-02 / 1 / 0.083
triterpenes / 7.66E-02 / 1 / 0.063
simple glc series / 8.52E-02 / 1 / 0.059
terpene lactones / 1.63E-01 / 1 / 0.040
monoacylglycerols / 2.17E-01 / 1 / 0.033
sesquiterpenes / 3.16E-01 / 1 / 0.026
1-(1z-alkenyl),2-acylglycerophosphoserines / 3.16E-01 / 1 / 0.026
diacylglycerophosphates / 3.60E-01 / 1 / 0.023
monoterpenes / 3.71E-01 / 1 / 0.023