Table S2 Genes that are both dCIN and CIN
Over-‐expressed gene
SL partners tested
YOR058C / ASE1 / YKR054C / DYN1 / drygin / Y
YDR488C / PAC11 / drygin
YCL029C / BIK1 / YOR349W / CIN1 / drygin / Y
YPL269W / KAR9 / drygin
YGR140W / CBF2 / YPL017C / IRC15 / drygin / Y / CBF3 complex
YDR318W / MCM21 / drygin
YPR120C / CLB5 / YMR198W / CIK1 / drygin / Y
YDL117W / CYK3 / drygin
YGL061C / DUO1 / YJL013C / MAD3 / drygin / Y / DASH complex
YMR055C / BUB2 / drygin
YOR025W / HST3 / YDR191W / HST4 / drygin / Y
YJR043W / POL32 / drygin
YKL089W / MIF2 / YPR046W / MCM16 / PMID: 16172405 / Y
YPL268W / PLC1 / PMID: 12756538
YIR002C / MPH1 / YJR075W / HOC1 / drygin / Y
YJR051W / OSM1 / drygin
YOR160W / MTR10 / YDR432W / NPL3 / PMID: 10952997 / Y
YJR042W / NUP85 / PMID: 9545233
YCL061C / MRC1 / YER173W / RAD24 / drygin / Y
YJR043W / POL32 / drygin
YBR073W / RDH54 / YKL053C-‐A / MDM35 / drygin / Y
YJL092W / SRS2 / drygin
YPR018W / RLF2 / YBL008W / HIR1 / drygin / Y / CAF1 comples
YOR038C / HIR2 / drygin
YDL139C / SCM3 / YPL018W / CTF19 / PMID: 21980305 / Y
YOR073W / SGO1 / YER016W / BIM1 / PMID: 15525520 / Y
YMR198W / CIK1 / PMID: 22319456
YBR156C / SLI15 / YHR129C / ARP1 / PMID: 18194531 / Y / CPC complex
YGR113W / DAM1 / PMID: 11724818
YHR172W / SPC97 / YDR356W / SPC110 / PMID: 9693376 / N / Tub4 complex
YLR200W / YKE2 / PMID: 9463374
YPL128C / TBF1 / YLR373C / VID22 / PMID: 17314980 / Y
YPL165C / SET6 / PMID: 17314980
YIL144W / TID3 / YKL052C / ASK1 / PMID: 14565975 / Y / Ndc80 complex
YGR140W / CBF2 / PMID: 11266451
YHR070W / TRM5 / YHR081W / LRP1 / PMID: 16155567 / Y
YDR164C / YDR164C / PMID: 16155567
YFL037W / TUB2 / YER155C / BEM2 / PMID: 14661025 / Y / tubulin complex
YCL029C / BIK1 / PMID: 2277073
YJL194W / CDC6 / YMR186W / HSC82 / drygin / Y
YML066C / SMA2 / drygin
YGR218W / CRM1 / YKL069W / YKL069W / drygin / Y
YKR082W / NUP133 / drygin
YDR363W / ESC2 / YBR228W / SLX1 / drygin / Y
YBR098W / MMS4 / drygin
YDR191W / HST4 / YOR024W / YOR024W / drygin / Y
YOR025W / HST3 / drygin
YIL150C / MCM10 / YDR150W / NUM1 / drygin / Y
YDL013W / SLX5 / drygin
YBL079W / NUP170 / YAR002W / NUP60 / drygin / Y / Nuclear pore
YGR081C / SLX9 / drygin
YLR032W / RAD5 / YML028W / TSA1 / drygin / Y
YER162C / RAD4 / drygin
YGL163C / RAD54 / YAR002W / NUP60 / drygin / Y
YJR043C / POL32 / drygin
YML114C / TAF8 / YNL119W / NCS2 / drygin / Y / TFIID
YPR023C / EAF3 / drygin
YGR270W / YTA7 / YOL054W / PSH1 / drygin / Y
YLR085C / ARP6 / drygin
YDR113C / PDS1 / YDR318W / MCM21 / SGD / Y
YOR349W / CIN1 / SGD
YOR195W / SLK19 / YPR141C / KAR3 / Drygin / Y
YMR198W / CIK1 / Drygin
YGL116W / CDC20 / YLR102C / APC9 / drygin / N / anaphase-‐promoting complex
YDR260C / SWM1 / drygin
YPL253C / VIK1 / YOR026W / BUB3 / drygin / N / SPB complex with Kar3
YOR014W / RTS1 / drygin
YDR386W / MUS81 / YMR055C / BUB2 / drygin / N / Holliday junction resolvase complex
YMR190C / SGS1 / drygin
YGL071W / AFT1 / YPR009W / SUT2 / drygin / N
YLR298C / yhc1-‐3 / drygin
YLR423C / ATG17 / YAL054C / ACS1 / drygin / N / Autophagy specific complex
YPR151C / SUE1 / drygin
YFL009W / CDC4 / YHR200W / RPN10 / drygin / N
YOR058C / ASE1 / drygin
YPR141C / KAR3 / YCR077C / PAT1 / drygin / N / SPB complex with Vik1
YGL086W / MAD1 / drygin
YAL040C / CLN3 / YER111C / SWI4 / drygin / N
YLL029W / FRA1 / drygin
YGR179C / OKP1 / YDR254W / CHL4 / PMID: 16172405 / N / COMA complex
YKL049C / CSE4 / PMID: 10958698
YHR027C / RPN1 / YDR363W-‐A / SEM1 / PMID: 15572408 / N / 26S proteosome
YMR186W / HSC82 / PMID: 12853471
YHR154W / RTT107 / YML028W / TSA1 / drygin / N
YMR190C / SGS1 / drygin
YKL193C / SDS22 / YOR027W / STI1 / drygin / N / PP1
YNL064C / YDJ1 / drygin
YLL028W / TPO1 / YNL236W / SIN4 / drygin / N
YAL002W / VPS8 / drygin
YML028W / TSA1 / YBR098W / MMS4 / drygin / N
YCR066W / RAD18 / drygin
YDR285W / ZIP1 / YHR123W / EPT1 / drygin / N / Synaptonemal complex (SC)
YDR404C YDR279W YNL072W YAL019W / RPB7 RNH202 RNH201 FUN30 / YER022W YJL140W YMR190C YMR190C YKL113C YOL081W YMR190C YJL013C / srb4-‐2 RPB4 SGS1 SGS1 RAD27 IRA2 SGS1 MAD3 / drygin PMID: 8488730
drygin drygin drygin drygin drygin drygin / N N N N / DNA-‐directed RNA polymerase II complex
RNAse H2
YBR060C / ORC2 / drygin
YKL113C / RAD27 / YOR033C / EXO1 / drygin / N
YPR164W / MMS1 / drygin
YPL190C / NAB3 / YOL081W / IRA2 / SGD / Y
YOR001W / RRP6 / SGD
YDR369C / XRS2 / YJR043W / POL32 / drygin / N
YHR031C / RRM3 / drygin
YKL049C / CSE4 / YBL008W / HIR1 / SGD / N / Sec61 complex
YPL018W / CTF19 / SGD
YGL044C / RNA15 / YML010C-‐B / YML010C-‐ / drygin / N
YLL045C / RPL8B / drygin
YOL006C / TOP1 / YHR167W / THP2 / drygin / N / mRNA cleavage factor complex
YJL124C / LSM1 / drygin
YLR357W / RSC2 / YHR129C / ARP1 / drygin / N
YER156C / YER156C / drygin
YKL108W / SLD2 / YJL090C / DPB11 / PMID: 9742127 / N / RSC complex
YLR103C / CDC45 / Drygin
YML065W / ORC1 / YBR060C / ORC2 / PMID: 20595233 / N / ORC
YMR055C / BUB2 / PMID: 16716188
YER133W / GLC7 / YDR158W / HOM2 / Drygin / N / CPF complex
YOR058C / ASE1 / Drygin
YGR274C / TAF1 / YJL115W / ASF1 / ygin, PMID:233906 / N / TFIID complex
YPR164W / MMS1 / Drygin
YHR031C / RRM3 / YDR363W / ESC2 / Drygin / N
YPR164W / MMS1 / Drygin
YJL115W / ASF1 / PMID:16327883
YHR164C / DNA2 / YOR033C / EXO1 / PMID:16327883 / N
YJL115W / ASF1 / Drygin
YIL026C / IRR1 / YOR144C / ELG1 / PMID:19430531 / N / Cohesin
YMR190C / SGS1 / Drygin
YJL092W / SRS2 / YDR363W / ESC2 / Drygin / N
YOL069W / NUF2 / YMR190C YGL086W / SGS1 MAD1 / Drygin PMID:23390603 / N / Ndc80 complex
YMR224C / MRE11 / PMID:23390603
YLR418C / CDC73 / PMID:23390603
ORF / Gene / OE mimics deletion / Complex
YHR027C / RPN1 / N / 26S proteosome
YLR423C / ATG17 / N / Autophagy specific complex
YGR179C / OKP1 / N / COMA complex
YDR404C / RPB7 / N / DNA-‐directed RNA polymerase II complex
YDR386W / MUS81 / N / Holliday junction resolvase complex
YGL044C / RNA15 / N / mRNA cleavage factor complex
YDR369C / XRS2 / N / MRX complex
YML065W / ORC1 / N / ORC
YKL193C / SDS22 / N / PP1
YJR068W / RFC2 / N / RF-‐C complex
YNL072W / RNH201 / N / RNAse H2
YLR357W / RSC2 / N / RSC complex
YLR378C / SEC61 / N / Sec61 complex
YPL253C / VIK1 / N / SPB complex with Kar3
YPR141C / KAR3 / N / SPB complex with Vik1
YDR285W / ZIP1 / N / Synaptonemal complex (SC)
YDR279W / RNH202 / N / RNAse H2
YGL116W / CDC20 / N / anaphase-‐promoting complex
YPR018W / RLF2 / Y / CAF1 comples
YGR140W / CBF2 / Y / CBF3 complex
YBR156C / SLI15 / Y / CPC complex
YGL061C / DUO1 / Y / DASH complex
YIL144W / TID3 / Y / Ndc80 complex
YBL079W / NUP170 / Y / Nuclear pore
YML114C / TAF8 / Y / TFIID
YHR172W / SPC97 / N / Tub4 complex
YFL037W / TUB2 / Y / tubulin complex
YER133W / GLC7 / N / CPF complex
YGR274C / TAF1 / N / TAFIID
YIL026C / IRR1 / N / Cohesin
YOL069W / NUF2 / N / Ndc80 complex