TABLE S1: Validation of Subsample of Self-Reported Incident Cancer Outcomes

Cancer / No. of Cancers Reported / Medical Records Obtained / No. of Cancers Confirmed / PPV (%)a
No. / %
All cancers excluding nonmelanoma skin cancer / 3813 / 2459 / 64 / 2241 / 91
Brain cancer / 30 / 16 / 53 / 3 / 19
Female breast cancer / 1436 / 1094 / 76 / 1076 / 98
Melanoma / 565 / 418 / 74 / 300 / 72
Basal cell carcinoma / 2057 / 1085 / 53 / 988 / 91
Squamous cell carcinoma / 560 / 98 / 18 / 81 / 83
Thyroid cancer / 151 / 128 / 85 / 113 / 88
Prostate cancer / 363 / 113 / 31 / 113 / 100
Lung and bronchial cancer / 99 / 28 / 28 / 28 / 100
Colorectal cancer / 249 / 150 / 60 / 133 / 89
Leukemia other than chronic lymphocytic leukemia / 29 / 21 / 72 / 17 / 81

aCalculated by number of confirmed reported cancers divided by the number for which medical records were obtained.

TABLE S2: Exclusions for Cancer Incidence Outcomes

Cancer Incidence / Baseline Cohort / Third Survey Missing / Race Not White / Cancer Status or Date Missing / Outcome Before Second Survey (Preexisting Condition) / Final No. in Incidence
Analysis Cohort
All cancer excluding nonmelanoma skin cancer / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Brain cancer / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Female breast cancer / 76,823 / 23,701 / 0 / 82 / 3102 / 49.938
Melanoma / 90,957 / 23,701 / 3236 / 105 / 3541 / 60,374
Basal cell carcinoma / 90,957 / 23,701 / 3236 / 370 / 6031 / 57,619
Squamous cell carcinoma / 90,957 / 23,701 / 3236 / 370 / 6031 / 57,619
Thyroid cancer / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Prostate cancer / 37,835 / 23,701 / 0 / 29 / 561 / 13,544
Lung or bronchial cancer / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Colorectal cancer / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Leukemia other than chronic lymphocytic leukemia / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482
Non-Hodgkin lymphoma / 90,957 / 23,701 / 0 / 111 / 3663 / 63,482

Note—Values are numbers of subjects.

TABLE S3: Exclusions for Cancer Mortality Outcomes

Cancer Mortality / Baseline Cohort / Death With Unknown Date / Death With Unknown Cause / Race Not White / Cancer Outcome or Date Missing / Outcome Before Second Survey (Preexisting Condition) / Final No. in Mortality Analysis Cohort
All cancer excluding nonmelanoma skin cancer / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952
Brain cancer / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952
Female breast cancer / 70,029 / 2 / 154 / 0 / 125 / 4626 / 65,122
Melanoma / 90,957 / 2 / 154 / 4868 / 158 / 5464 / 80,311
Prostate cancer / 21,084 / 2 / 154 / 0 / 43 / 1055 / 19,830
Lung or bronchus cancer / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952
Colorectal cancer / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952
Leukemia other than chronic lymphocytic leukemia / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952
Non-Hodgkin lymphoma / 90,957 / 2 / 154 / 0 / 168 / 5681 / 84,952

Note—Values are numbers of subjects.

TABLE S4: Number of Events and Person-Years at Risk of Selected Cancer Outcomes Associated With Working With Fluoroscopically Guided Interventional Procedures Among U.S. Radiologic Technologists Who Completed Second Survey (1994–1998)

Experience With Procedures / Incidence / Mortality
No. of Cases / Person-Years at Risk / No. of Deaths / Person-Years at Risk
All cancer excluding nonmelanoma skin cancer / 2431 / 367,975 / 4202 / 742,621
Never
Ever / 900 / 141,233 / 1319 / 282,532
Unknown / 406 / 54,435 / 1460 / 122,343
Brain cancer
Never / 12 / 367,975 / 34 / 698,389
Ever / 4 / 141,233 / 26 / 268,044
Unknown / 1 / 54,435 / 11 / 112,701
Female breast cancer
Never / 962 / 304,771 / 97 / 568,070
Ever / 324 / 97,381 / 28 / 180,104
Unknown / 152 / 42,988 / 20 / 87,354
Melanoma
Never / 288 / 352,097 / 25 / 698,389
Ever / 141 / 133,777 / 6 / 268,044
Unknown / 48 / 50,781 / 7 / 112,701
Basal cell carcinoma / NA
Never / 1427 / 329,681
Ever / 501 / 125,899
Unknown / 214 / 46,778
Squamous cell carcinoma / NA
Never / 418 / 329,681
Ever / 144 / 125,899
Unknown / 72 / 46,778
Thyroid cancer / NA
Never / 96 / 367,975
Ever / 32 / 141,233
Unknown / 10 / 54,435
Prostate cancer
Never / 211 / 63,204 / 15 / 130,319
Ever / 114 / 43,852 / 8 / 87,939
Unknown / 45 / 11,447 / 8 / 25,347
Lung cancer
Never / 70 / 367,975 / 288 / 698,389
Ever / 19 / 141,233 / 94 / 268,044
Unknown / 11 / 54,435 / 85 / 112,701
Colorectal cancer
Never / 159 / 367,975 / 79 / 698,389
Ever / 48 / 141,233 / 20 / 268,044
Unknown / 36 / 54,435 / 29 / 112,701
Leukemia other than chronic lymphocytic leukemia
Never / 19 / 367,975 / 31 / 698,389
Ever / 6 / 141,233 / 16 / 268,044
Unknown / 1 / 54,435 / 8 / 112,701

Note—NA = not applicable.

TABLE S5: Incidence Rates per Hundred Thousand Person-Years for Cancer Outcomes in U.S. Radiologic Technologists 1994–2008 (USRT) Compared With Estimated Age-Adjusted U.S. Surveillance, Epidemiology, and End Results (SEER) Based on 2008–2012 Cases and Deaths

Incidencea / Mortality
USRT / SEER / USRT / SEER
Brain cancer / 2.4 / 6.4 / 6.6 / 4.3
Female breast cancer / 308 / 124.8 / 17.4 / 21.9
Melanoma / 82.2 / 21.6 / 3.7 / 2.7
Basal cell carcinoma / 428.2 / NA / NA / NA
Squamous cell carcinoma / 154.7 / NA / NA / NA
Thyroid cancer / 17.4 / 13.5 / NA / 0.5
Prostate cancer / 305.3 / 137.9 / 12.7 / 21.4
Lung cancer / 22.4 / 58.8 / 43.3 / 47.2
Colorectal cancer / 53.2 / 42.4 / 11.9 / 15.5
Leukemia other than chronic lymphocytic leukemia / 4.4 / NA / 5.1 / NA

Note—NA = not applicable.

aRates per 100,000 individuals. Age-adjusted U.S. general population rates are based on malignant cancers from the National Cancer Institute SEER program, 2008–2012.

AJR:206, May 2016 1