TABLE S1. Clusters of orthologous genes (COGs) of H. boliviensis related to carbon transport and metabolism.

‡ Refers to the number of alleles and the cluster that the alleles formed with: P, proteobacteria; B, bacteria; T, thermophilic archaea; HA, halophilic archaea; combinations of these groups of organisms and NC denotes that no cluster was formed.

COG / Protein function / Number of alleles / Clusters formed by the alleles‡
21 / Transketolase / 1 / P
33 / Phosphoglucomutase / 1 / B
36 / Pentose-5-phosphate-3-epimerase / 1 / P
57 / Glyceraldehyde-3-phosphate dehydrogenase / erythrose-4-phosphate dehydrogenase / 4 / 4 P
61 / Predicted sugar kinase / 1 / P
63 / Predicted sugar kinase / 1 / B
120 / Ribose 5-phosphate isomerase / 1 / P
126 / 3-phosphoglycerate kinase / 1 / P
148 / Enolase / 1 / P
149 / Triosephosphate isomerase / 1 / P
166 / Glucose-6-phosphate isomerase / 2 / 2 - B
176 / Transaldolase / 1 / P
191 / Fructose/tagatose bisphosphate aldolase / 1 / P
205 / 6-phosphofructokinase / 1 / B
235 / Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases / 3 / 2 - P
1 - B
246 / Mannitol-1-phosphate/altronate dehydrogenases / 2 / 1 - P
1 - NC
279 / Phosphoheptose isomerase / 2 / 1- P
1 - B
363 / 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase / 1 / P
364 / Glucose-6-phosphate 1-dehydrogenase / 1 / P
366 / Glycosidases / 2 / 2 - B
395 / ABC-type sugar transport system, permease component / 7 / 1- P
4 - B
1 - B, HA
1 - B, T
406 / Fructose-2,6-bisphosphatase / 3 / 1- P
2 - B
469 / Pyruvate kinase / 2 / 2 - P
483 / Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family / 4 / 1- P
1 - B
2 - B, HA
524 / Sugar kinases, ribokinase family / 3 / 3 - B
574 / Phosphoenolpyruvate synthase/pyruvate phosphate dikinase / 1 / P
662 / Mannose-6-phosphate isomerase / 1 / B
676 / Uncharacterized enzymes related to aldose 1-epimerase / 1 / B
696 / Phosphoglyceromutase / 1 / P
726 / Predicted xylanase/chitin deacetylase / 2 / 1- P
1 - B
800 / 2-keto-3-deoxy-6-phosphogluconate aldolase / 2 / 1- P
1 - HA
837 / Glucokinase / 1 / P
1015 / Phosphopentomutase / 1 / P
1070 / Sugar (pentulose and hexulose) kinases / 2 / 2 - B
1080 / Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) / 1 / B
1082 / Sugar phosphate isomerases/epimerases / 2 / 2 - B
1105 / Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) / 1 / B
1109 / Phosphomannomutase / 2 / 1- P
1 - B, T
1129 / ABC-type sugar transport system, ATPase component / 3 / 1- P
1 - B
1 - B, T
1172 / Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components / 3 / 2 - B
1 - T
1175 / ABC-type sugar transport systems, permease components / 7 / 1 - B
4 - B, T
2 - B, HA
1299 / Phosphotransferase system, fructose-specific IIC component / 1 / P
1312 / D-mannonate dehydratase / 1 / B
1363 / Cellulase M and related proteins / 1 / B
1472 / Beta-glucosidase-related glycosidases / 1 / P
1593 / TRAP-type C4-dicarboxylate transport system, large permease component / 15 / 6- P
5 - B
1 - B, HA
3 - NC
1638 / TRAP-type C4-dicarboxylate transport system, periplasmic component / 17 / 6- P
5 - B
6 - NC
1653 / ABC-type sugar transport system, periplasmic component / 7 / 3- P
3 - B
1 - T
1803 / Methylglyoxal synthase / 1 / B
1830 / DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes / 1 / B
1850 / Ribulose 1,5-bisphosphate carboxylase, large subunit / 1 / B
1879 / ABC-type sugar transport system, periplasmic component / 3 / 2 - B
1 - B, T
1929 / Glycerate kinase / 1 / B
2017 / Galactose mutarotase and related enzymes / 1 / B
2133 / Glucose/sorbosone dehydrogenases / 1 / HA
2513 / PEP phosphonomutase and related enzymes / 1 / P
2721 / Altronate dehydratase / 1 / B
2814 / Arabinose efflux permease / 4 / 4 - NC
2956 / Predicted N-acetylglucosaminyl transferase / 1 / P
3090 / TRAP-type C4-dicarboxylate transport system, small permease component / 11 / 2- P
6 - B
2 - B, HA
1 - NC
3265 / Gluconate kinase / 1 / B
3386 / Gluconolactonase / 1 / B
3459 / Cellobiose phosphorylase / 1 / B
3693 / Beta-1,4-xylanase / 1 / B
3717 / 5-keto 4-deoxyuronate isomerase / 1 / B
3718 / Uncharacterized enzyme involved in inositol metabolism / 1 / B
3734 / 2-keto-3-deoxy-galactonokinase / 1 / B
3839 / ABC-type sugar transport systems, ATPase components / 9 / 1- P
6 - B
1 - T
1 - B, T
3936 / Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation / 1 / B
4678 / Muramidase (phage lambda lysozyme) / 1 / P
4993 / Glucose dehydrogenase / 2 / 2- P