Table S1. Characteristics of Women Included in the Study

Table S1. Characteristics of women included in the study.

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Characteristic Normal PretermLOPEEOPE

(n=23)(n=4)(n=10)(n=8)

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Age (years± SEM) a29.0± 1.725.5 ± 2.422.3± 2.131.1± 2.6

Weight initial (kg ± SEM)66.3± 2.866.5 ± 1.363.5 ± 3.562.6± 3.2

Weight (kg ± SEM)78.9± 2.773.1 ± 1.179.6± 4.172.5± 3.3

Height (cm ± SEM) a156± 1.5165± 1.8159± 2.0153± 2.0‡

Parity (mean ± SEM)1.4± 0.21.0± 0.70.7± 0.32.1± 0.5

Nulliparous n (%)4 (17%)2 (50%)4 (40%)3 (25%)

Gestational age (wk)a38.6± 0.330.7± 2.6*37.6± 0.7‡32.0± 0.6*†

Cesarean, n (%)13 (56%)2 (50%)6 (60%)4 (50%)

Hospitalization (days)a2.6± 0.63.6± 0.93.0± 0.56.2± 1.7*†

SBP (mmHg)a116± 1.9103± 4.1146± 2.1*‡157± 7.2*‡

DBP (mmHg) a69.8± 1.564.7± 5.193.3± 1.6*‡ 97± 3.5*‡

Biochemical parameters

Proteinuria (mg/24h ± SEM) a00708±382*1483± 437*

LDH (mean ± SEM) (n) aNANA210± 8.7 (4)362± 44 (4)†

A. phosphatase (mean ± SEM) (n)NANA189± 21 (6)173±37 (7)

GOT (mean ± SEM) (n)NANA13.8± 1.8 (7)22.5± 7.2 (6)

GPT (mean ± SEM) (n)NANA9.7± 0.8 (7)24.4± 8.1 (7)

Creatinine (mean ± SEM) (n)0.7 ± 0.03 (7)0.8 ± 0.02 (4)0.6± 0.07 (7)0.6± 0.08 (7)

Platelets (#*103/ml ± SEM) (n)223± 22 (15)203± 21 (4)186± 17 (9)156±35 (7)

Uric acid (mg/dl ± SEM) (n)NANA4.4± 0.5 (8)4.6± 0.5 (7)

Hemoglobin (mg/dl ± SEM) (n)11.9± 0.2 (18)10.4± 0.5 (4)12.2± 0.4 (10)12.5± 0.7 (8)

Leucocytes (#*103/ml ± SEM)(n)12.1± 0.1 (15)9.8 ± 0.7 (4)12.5± 1.3 (8)14.2± 1.1 (8)‡

Table S1. Continue.

Newborn

Male/Female13/103/16/45/3

Weight (g ± SEM) a3371±831809± 495*3077± 2121666± 182*†

Percentilea57.2± 4.757.5± 7.554.5± 7.935± 11*†

SGA, n (%)001 (10%)2 (25%)

Height (cm ± SEM) a48.7± 0.441.7± 4.0*47.2± 1.139.8± 1.2*†

Cephalic perimeter (cm ± SEM) a34.0± 0.230.8± 1.9*34.1± 0.629.1± 0.5*

Apgar 1 mina8.3± 0.37.0± 1.68.9± 0.16.0± 1.1*†

Apgar 5 mina8.9 ± 0.29.0 ± 0.09.3± 0.18.0 ± 0.5*†

Placenta

Weight (g ± SEM)a544±25385± 94.3516± 45318±26*†

Area (m2± SEM)a3.9± 0.31.5 ± 0.4*2.8± 0.3*1.4± 0.2*†

NBW/PlW (g ± SEM) a6.4± 0.24.6± 0.2*6.1± 0.35.3± 0.5

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SBP, systolic blood pressure. DBP, diastolic blood pressure. NBW, newborn weight. PlW, placental weight. ap<0.05 in ANOVA. *p<0.05 vs normal pregnancy. †p<0.05 vs late-onset pre-eclampsia. ‡p<0.05 vs preterm delivery. Values are mean ± SEM.