Tikka-Kleemola et al.

Table e-1. Families with migraine with aura who were used for genome-wide screen

Family number / Subjects / Genotyped subjects / Generations
a / Subjects with visual aura / Scintillating scotoma
23 / 15 / 13 / 4 / 8 / 7
104 / 9 / 5 / 3 / 3 / 3
107 / 6 / 5 / 3 / 4 / 3
119 / 18 / 13 / 4 / 7 / 7
170 / 8 / 8 / 3 / 4 / 4
181 / 10 / 8 / 4 / 2 / 2
190 / 16 / 14 / 4 / 5 / 4
214 / 12 / 9 / 4 / 6 / 5
234 / 25 / 14 / 4 / 7 / 7
241 / 15 / 7 / 4 / 3 / 3
245 / 13 / 12 / 3 / 7 / 5
287 / 22 / 18 / 4 / 6 / 6
305 / 6 / 3 / 3 / 2 / 2
317 / 8 / 5 / 3 / 5 / 4
346 / 20 / 18 / 3 / 12 / 12
348 / 12 / 12 / 3 / 4 / 3
427 / 10 / 8 / 3 / 4 / 4
430 / 15 / 10 / 3 / 5 / 2
438 / 34 / 19 / 5 / 10 / 10
466 / 15 / 9 / 3 / 7 / 7
467 / 16 / 10 / 4 / 6 / 4
480 / 21 / 15 / 3 / 8 / 6
496 / 11 / 10 / 3 / 5 / 4
575 / 14 / 11 / 4 / 6 / 5
732 / 16 / 12 / 4 / 5 / 3
736 / 9 / 4 / 4 / 4 / 3
737 / 7 / 6 / 3 / 4 / 4
749 / 15 / 12 / 3 / 5 / 4
752 / 15 / 11 / 3 / 4 / 4
753 / 14 / 8 / 3 / 6 / 5
759 / 13 / 10 / 3 / 4 / 3
767 / 9 / 6 / 4 / 3 / 3
778 / 10 / 8 / 4 / 3 / 2
1010 / 8 / 4 / 3 / 3 / 3
1013 / 9 / 9 / 3 / 5 / 3
1035 / 6 / 5 / 3 / 3 / 3
Mean / 13.4 / 9.8 / 3.4 / 5.1 / 4.4
Range / 6-34 / 3-19 / 3-5 b / 2-12 / 2-12
Mode c / 15 / 8 / 3 / 4 / 3
Total / 482 d / 351 / 36 / 185 / 159

a Includes all family members

b This range includes 21 families with 3 generations, 14 families with 4 generations and 1 family with 5 generations

c Mode = the value that occurs most frequently

d This number includes 131 individuals that have not provided blood sample but are important for linkage information