Table 3. Discrete Choice (Multinomial Logit) Model for Attribute Main Effects by Breast Cancer Risk

High / Mod / Low
Attributes / Levels / Coeff.
(B) / Stand.
error / t-ratio / P / Coeff.
(B) / Stand.
error / t-ratio / P / Coeff
(B). / Stand.
error / t-ratio / P
Staff seen / Consultant geneticist / 0.807891 / 0.141549 / 5.70752 / <0.01 / 0.491716 / 0.170988 / 2.87574 / <0.01 / 0.97999 / 0.22261 / 4.40227 / <0.01
Specialist genetics nurse / -0.236943 / 0.168232 / -1.40842 / 0.16 / -0.420656 / 0.215173 / -1.95497 / 0.051 / -0.0541286 / 0.272415 / -0.198699 / 0.84
Genetics associate / -0.570949 / 0.19557 / -2.9194 / <0.01 / -0.0710607 / 0.221015 / -0.321519 / 0.75 / -0.925861 / 0.325543 / -2.84405 / <0.01
Waiting time for letter / 1 month / 1.11917 / 0.170467 / 6.56535 / <0.01 / 1.35704 / 0.220161 / 6.16388 / <0.01 / 1.53943 / 0.236039 / 6.52194 / <0.01
2 month / 0.605685 / 0.173166 / 3.49771 / <0.01 / 0.67439 / 0.186318 / 3.61956 / <0.01 / 0.592422 / 0.268097 / 2.20972 / <0.05
4 month / -0.524831 / 0.18471 / -2.84138 / <0.01 / -0.458103 / 0.209609 / -2.18552 / <0.05 / -0.816564 / 0.287491 / -2.84031 / <0.01
6 month / -1.20003 / 0.246208 / -4.87403 / <0.01 / -1.57333 / 0.314447 / -5.00348 / <0.01 / -1.31529 / 0.378583 / -3.47423 / <0.01
Distance to counselling / 20 miles / 0.281293 / 0.199913 / 1.40708 / 0.16 / 0.396118 / 0.24968 / 1.5865 / 0.11 / 0.864855 / 0.264548 / 3.26919 / <0.01
40 miles / 0.693696 / 0.183402 / 3.78237 / <0.01 / 0.503089 / 0.251902 / 1.99716 / <0.05 / 0.376671 / 0.313274 / 1.20237 / 0.23
60 miles / -0.996691 / 0.224472 / -4.44015 / <0.01 / -0.776432 / 0.265125 / -2.92855 / <0.01 / -0.984584 / 0.338389 / -2.90962 / <0.01
80 miles / 0.0217017 / 0.175119 / 0.123926 / 0.90 / -0.122775 / 0.212643 / -0.577378 / 0.56 / -0.256943 / 0.272386 / -0.943306 / 0.35
Duration of counselling / 30 minutes / -1.48606 / 0.26215 / -5.66874 / <0.01 / -0.599724 / 0.281687 / -2.12904 / <0.05 / -0.468109 / 0.327934 / -1.42745 / 0.15
1 hour / 0.365709 / 0.183933 / 1.98827 / <0.05 / 0.326822 / 0.21628 / 1.51111 / 0.13 / 0.192295 / 0.269646 / 0.71314 / 0.48
1 hour 30 minutes / 0.470156 / 0.188568 / 2.49329 / 0.05 / 0.220217 / 0.253228 / 0.869637 / 0.38 / 0.502277 / 0.300013 / 1.67419 / 0.09
2 hour / 0.650198 / 0.15015 / 4.33032 / <0.01 / 0.0526849 / 0.215712 / 0.244237 / 0.81 / -0.226463 / 0.25723 / -0.880393 / 0.38
Availability of testing / High risk / 0.0816467 / 0.115888 / 0.70453 / 0.48 / -0.874926 / 0.143116 / -6.11339 / <0.01 / -0.587836 / 0.193233 / -3.04211 / <0.01
All / -0.0816467 / 0.115888 / -0.70453 / 0.48 / 0.874926 / 0.143116 / 6.11339 / <0.01 / 0.587836 / 0.193233 / 3.04211 / <0.01
Cost of service / £1,500 / 0.402371 / 0.195398 / 2.05924 / <0.05 / 0.821968 / 0.209772 / 3.91839 / <0.01 / 0.20546 / 0.301281 / 0.681956 / 0.50
£2,000 / 0.440799 / 0.194548 / 2.26576 / <0.05 / 0.336268 / 0.274772 / 1.22381 / 0.22 / 0.263439 / 0.352492 / 0.747363 / 0.45
£2,500 / 0.170999 / 0.161888 / 1.05628 / 0.29 / -0.39732 / 0.209167 / -1.89954 / 0.06 / 0.142046 / 0.25221 / 0.563205 / 0.57
£3,000 / -1.01417 / 0.243535 / -4.16436 / <0.01 / -0.760915 / 0.255786 / -2.97481 / <0.01 / -0.610946 / 0.357107 / -1.71082 / 0.09
N = / 30 / 32 / 19
Number of observations / 678 / 736 / 437
Log likelihood function / -552.6894 / -514.4619 / -299.6787
Restricted log likelihood / -552.6894 / -514.4619 / -299.6787
McFadden’s R2 / 0.25799 / 0.36375 / 0.37579
Adjusted McFadden’s R2 / 0.24969. / 0.35720 / 0.36489

Table 4. Utility (preference) of the Cancer Genetic Services Configurations and their Cost per Patient

Service configuration scenarios for event pathway 15 / Utility
score / Mean
cost / Utility
ranking / Cost
ranking
Staff / Wait / Distance / Duration
Consultant geneticist / 1 month / 40 miles / 2 hours / 3.270955 / £3,645 / 1 / 63
Consultant geneticist / 1 month / 40 miles / 1 hour 30 / 3.090913 / £3,357 / 2 / 59
Consultant geneticist / 1 month / 40 miles / 1 hour / 2.986466 / £3,064 / 3 / 55
Consultant geneticist / 2 month / 40 miles / 2 hours / 2.75747 / £3,645 / 4 / 63
Consultant geneticist / 2 month / 40 miles / 1 hour 30 / 2.577428 / £3,357 / 5 / 59
Consultant geneticist / 2 month / 40 miles / 1 hour / 2.472981 / £3,064 / 6 / 55
Genetics associate / 1 month / 40 miles / 2 hours / 1.892115 / £2,855 / 7 / 49
Genetics associate / 1 month / 40 miles / 1 hour 30 / 1.712073 / £2,692 / 8 / 39
Consultant geneticist / 4 month / 40 miles / 2 hours / 1.626954 / £2,951 / 9 / 53
Genetics associate / 1 month / 40 miles / 1 hour / 1.607626 / £2,525 / 10 / 29
Consultant geneticist / 1 month / 60 miles / 2 hours / 1.580568 / £3,466 / 11 / 61
Consultant geneticist / 4 month / 40 miles / 1 hour 30 / 1.446912 / £2,757 / 12 / 41
Consultant geneticist / 1 month / 60 miles / 1 hour 30 / 1.400526 / £3,178 / 13 / 57
Genetics associate / 2 month / 40 miles / 2 hours / 1.37863 / £2,855 / 14 / 49
Consultant geneticist / 4 month / 40 miles / 1 hour / 1.342465 / £2,559 / 15 / 31
Consultant geneticist / 1 month / 60 miles / 1 hour / 1.296079 / £2,892 / 16 / 51
Genetics associate / 2 month / 40 miles / 1 hour 30 / 1.198588 / £2,692 / 17 / 39
Consultant geneticist / 1 month / 40 miles / 30 minutes / 1.134697 / £2,778 / 18 / 45
Genetics associate / 2 month / 40 miles / 1 hour / 1.094141 / £2,525 / 19 / 29
Consultant geneticist / 2 month / 60 miles / 2 hours / 1.067083 / £3,466 / 20 / 61
Consultant geneticist / 6 month / 40 miles / 2 hours / 0.951755 / £2,951 / 21 / 53
Consultant geneticist / 2 month / 60 miles / 1 hour 30 / 0.887041 / £3,178 / 22 / 57
Consultant geneticist / 2 month / 60 miles / 1 hour / 0.782594 / £2,892 / 23 / 51
Consultant geneticist / 6 month / 40 miles / 1 hour 30 / 0.771713 / £2,757 / 24 / 41
Consultant geneticist / 6 month / 40 miles / 1 hour / 0.667266 / £2,559 / 25 / 31
Consultant geneticist / 2 month / 40 miles / 30 minutes / 0.621212 / £2,778 / 26 / 45
Genetics associate / 4 month / 40 miles / 2 hours / 0.248114 / £2,424 / 27 / 23
Genetics associate / 1 month / 60 miles / 2 hours / 0.201728 / £2,758 / 28 / 43
Genetics associate / 4 month / 40 miles / 1 hour 30 / 0.068072 / £2,313 / 29 / 15
Genetics associate / 1 month / 60 miles / 1 hour 30 / 0.021686 / £2,598 / 30 / 33
Genetics associate / 4 month / 40 miles / 1 hour / -0.03638 / £2,200 / 31 / 7
Consultant geneticist / 4 month / 60 miles / 2 hours / -0.06343 / £2,821 / 32 / 47
Genetics associate / 1 month / 60 miles / 1 hour / -0.08276 / £2,438 / 33 / 27
Consultant geneticist / 4 month / 60 miles / 1 hour 30 / -0.24348 / £2,630 / 34 / 37
Genetics associate / 1 month / 40 miles / 30 minutes / -0.24414 / £2,368 / 35 / 19
Genetics associate / 2 month / 60 miles / 2 hours / -0.31176 / £2,758 / 36 / 43
Consultant geneticist / 4 month / 60 miles / 1 hour / -0.34792 / £2,436 / 37 / 25
Genetics associate / 6 month / 40 miles / 2 hours / -0.42709 / £2,424 / 38 / 23
Genetics associate / 2 month / 60 miles / 1 hour 30 / -0.4918 / £2,598 / 39 / 33
Consultant geneticist / 4 month / 40 miles / 30 minutes / -0.5093 / £2,369 / 40 / 21
Consultant geneticist / 1 month / 60 miles / 30 minutes / -0.55569 / £2,605 / 41 / 35
Genetics associate / 2 month / 60 miles / 1 hour / -0.59625 / £2,438 / 42 / 27
Genetics associate / 6 month / 40 miles / 1 hour 30 / -0.60713 / £2,313 / 43 / 15
Genetics associate / 6 month / 40 miles / 1 hour / -0.71157 / £2,200 / 44 / 7
Consultant geneticist / 6 month / 60 miles / 2 hours / -0.73863 / £2,821 / 45 / 47
Genetics associate / 2 month / 40 miles / 30 minutes / -0.75763 / £2,368 / 46 / 19
Consultant geneticist / 6 month / 60 miles / 1 hour 30 / -0.91867 / £2,630 / 47 / 37
Consultant geneticist / 6 month / 60 miles / 1 hour / -1.02312 / £2,436 / 48 / 25
Consultant geneticist / 2 month / 60 miles / 30 minutes / -1.06918 / £2,605 / 49 / 35
Consultant geneticist / 6 month / 40 miles / 30 minutes / -1.1845 / £2,369 / 50 / 21
Genetics associate / 4 month / 60 miles / 2 hours / -1.44227 / £2,350 / 51 / 17
Genetics associate / 4 month / 60 miles / 1 hour 30 / -1.62232 / £2,242 / 52 / 9
Genetics associate / 4 month / 60 miles / 1 hour / -1.72676 / £2,135 / 53 / 5
Genetics associate / 4 month / 40 miles / 30 minutes / -1.88814 / £2,095 / 54 / 3
Genetics associate / 1 month / 60 miles / 30 minutes / -1.93453 / £2,278 / 55 / 13
Genetics associate / 6 month / 60 miles / 2 hours / -2.11747 / £2,350 / 56 / 17
Consultant geneticist / 4 month / 60 miles / 30 minutes / -2.19969 / £2,245 / 57 / 11
Genetics associate / 6 month / 60 miles / 1 hour 30 / -2.29751 / £2,242 / 58 / 9
Genetics associate / 6 month / 60 miles / 1 hour / -2.40196 / £2,135 / 59 / 5
Genetics associate / 2 month / 60 miles / 30 minutes / -2.44802 / £2,278 / 60 / 13
Genetics associate / 6 month / 40 miles / 30 minutes / -2.56334 / £2,095 / 61 / 3
Consultant geneticist / 6 month / 60 miles / 30 minutes / -2.87489 / £2,245 / 62 / 11
Genetics associate / 4 month / 60 miles / 30 minutes / -3.57853 / £2,027 / 63 / 1
Genetics associate / 6 month / 60 miles / 30 minutes / -4.25373 / £2,027 / 64 / 1

Note: signifies the separation of quartiles.