Supplementary Table S1A. Transcripts Upregulated 2-Fold Following Mir-34B Overexpression

Supplementary Table S1A. Transcripts upregulated ≥ 2-fold following miR-34b overexpression in MCF-7 cells.

Symbol / Fold Change ± SD / P-value / Accession Number / Definition
IFIT3 / 13.64 ± 0.79 / 4.68E-04 / NM_001031683.1 / Homo sapiens interferon-induced protein with tetratricopeptide repeats 3 (IFIT3), mRNA.
IFIT2 / 13.59 ± 1.74 / 1.64E-03 / NM_001547.3 / Homo sapiens interferon-induced protein with tetratricopeptide repeats 2 (IFIT2), mRNA.
HLA-B / 13.34 ± 0.80 / 1.90E-04 / NM_005514.5 / Homo sapiens major histocompatibility complex, class I, B (HLA-B), mRNA.
OAS2 / 11.19 ± 0.95 / 1.31E-04 / NM_002535.2 / Homo sapiens 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2), transcript variant 2, mRNA.
RARRES3 / 11.09 ± 1.19 / 3.21E-03 / NM_004585.2 / Homo sapiens retinoic acid receptor responder (tazarotene induced) 3 (RARRES3), mRNA.
CCL5 / 10.95 ± 1.49 / 8.66E-03 / NM_002985.2 / Homo sapiens chemokine (C-C motif) ligand 5 (CCL5), mRNA.
HCP5 / 10.06 ± 1.76 / 1.82E-02 / NM_006674.2 / Homo sapiens HLA complex P5 (HCP5), mRNA.
MX2 / 9.41 ± 0.78 / 3.38E-04 / NM_002463.1 / Homo sapiens myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA.
XAF1 / 8.73 ± 0.47 / 7.20E-04 / NM_199139.1 / Homo sapiens XIAP associated factor 1 (XAF1), transcript variant 2, mRNA.
OASL / 8.64 ± 0.47 / 1.82E-03 / NM_003733.2 / Homo sapiens 2'-5'-oligoadenylate synthetase-like (OASL), transcript variant 1, mRNA.
IFNB1 / 7.49 ± 0.54 / 7.57E-04 / NM_002176.2 / Homo sapiens interferon, beta 1, fibroblast (IFNB1), mRNA.
IGFBP6 / 7.10 ± 1.21 / 1.71E-02 / NM_002178.2 / Homo sapiens insulin-like growth factor binding protein 6 (IGFBP6), mRNA.
TAP1 / 6.88 ± 0.99 / 7.46E-03 / NM_000593.5 / Homo sapiens transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (TAP1), mRNA.
IFI35 / 6.49 ± 0.18 / 9.02E-05 / NM_005533.2 / Homo sapiens interferon-induced protein 35 (IFI35), mRNA.
IFI44L / 6.15 ± 0.51 / 3.88E-03 / NM_006820.1 / Homo sapiens interferon-induced protein 44-like (IFI44L), mRNA.
SAMD9 / 6.07 ± 0.77 / 4.76E-03 / NM_017654.2 / Homo sapiens sterile alpha motif domain containing 9 (SAMD9), mRNA.
HERC5 / 5.89 ± 0.34 / 7.14E-04 / NM_016323.1 / Homo sapiens hect domain and RLD 5 (HERC5), mRNA.
PSMB8 / 5.89 ± 0.29 / 3.69E-04 / NM_148919.3 / Homo sapiens proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2, mRNA.
UBE2L6 / 5.53 ± 0.27 / 1.25E-03 / NM_198183.1 / Homo sapiens ubiquitin-conjugating enzyme E2L 6 (UBE2L6), transcript variant 2, mRNA.
PSMB9 / 5.52 ± 0.16 / 3.35E-04 / NM_002800.4 / Homo sapiens proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) (PSMB9), transcript variant 1, mRNA.
HLA-H / 5.46 ± 0.73 / 6.93E-03 / NR_001434.1 / Homo sapiens major histocompatibility complex, class I, H (pseudogene) (HLA-H), non-coding RNA.
HLA-A29.1 / 5.33 ± 0.49 / 2.47E-03 / NM_001080840.1 / Homo sapiens major histocompatibility complex class I HLA-A29.1 (HLA-A29.1), mRNA.
GBP1 / 5.28 ± 0.19 / 6.36E-04 / NM_002053.1 / Homo sapiens guanylate binding protein 1, interferon-inducible, 67kDa (GBP1), mRNA.
DIO2 / 5.04 ± 0.07 / 1.35E-05 / NM_013989.2 / Homo sapiens deiodinase, iodothyronine, type II (DIO2), transcript variant 1, mRNA.
OAS1 / 5.03 ± 0.09 / 2.50E-04 / NM_002534.2 / Homo sapiens 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, mRNA.
FGD3 / 5.01 ± 0.61 / 1.08E-02 / NM_033086.1 / Homo sapiens FYVE, RhoGEF and PH domain containing 3 (FGD3), transcript variant 2, mRNA.
UBA7 / 5.00 ± 0.36 / 1.08E-03 / NM_003335.2 / Homo sapiens ubiquitin-like modifier activating enzyme 7 (UBA7), mRNA.
LGALS3BP / 4.96 ± 0.25 / 1.64E-03 / NM_005567.2 / Homo sapiens lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP), mRNA.
HLA-F / 4.91 ± 0.50 / 5.72E-03 / NM_018950.1 / Homo sapiens major histocompatibility complex, class I, F (HLA-F), transcript variant 1, mRNA.
PARP14 / 4.90 ± 0.09 / 1.40E-05 / NM_017554.1 / Homo sapiens poly (ADP-ribose) polymerase family, member 14 (PARP14), mRNA.
TMEM140 / 4.79 ± 0.44 / 4.81E-03 / NM_018295.1 / Homo sapiens transmembrane protein 140 (TMEM140), mRNA.
SLC15A3 / 4.68 ± 0.25 / 1.13E-04 / NM_016582.1 / Homo sapiens solute carrier family 15, member 3 (SLC15A3), mRNA.
ZNFX1 / 4.63 ± 0.23 / 1.42E-03 / NM_021035.1 / Homo sapiens zinc finger, NFX1-type containing 1 (ZNFX1), mRNA.
TNFSF10 / 4.61 ± 0.50 / 7.09E-04 / NM_003810.2 / Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), mRNA.
C19orf66 / 4.59 ± 0.31 / 1.73E-04 / NM_018381.1 / Homo sapiens chromosome 19 open reading frame 66 (C19orf66), mRNA.
TNS3 / 4.50 ± 0.70 / 1.37E-02 / NM_022748.9 / Homo sapiens tensin 3 (TNS3), mRNA.
USP18 / 4.43 ± 0.50 / 9.12E-03 / NM_017414.3 / Homo sapiens ubiquitin specific peptidase 18 (USP18), mRNA.
WARS / 4.41 ± 0.10 / 5.29E-05 / NM_213646.1 / Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 2, mRNA.
PARP10 / 4.39 ± 0.31 / 3.37E-03 / NM_032789.1 / Homo sapiens poly (ADP-ribose) polymerase family, member 10 (PARP10), mRNA.
PARP12 / 4.36 ± 0.32 / 2.95E-03 / NM_022750.2 / Homo sapiens poly (ADP-ribose) polymerase family, member 12 (PARP12), mRNA.
IFITM1 / 4.32 ± 0.17 / 2.01E-04 / NM_003641.2 / Homo sapiens interferon induced transmembrane protein 1 (9-27) (IFITM1), mRNA.
CFB / 4.28 ± 0.47 / 4.94E-03 / NM_001710.4 / Homo sapiens complement factor B (CFB), mRNA.
IL29 / 4.16 ± 0.22 / 1.12E-03 / NM_172140.1 / Homo sapiens interleukin 29 (interferon, lambda 1) (IL29), mRNA.
IRF1 / 4.16 ± 0.46 / 9.32E-03 / NM_002198.1 / Homo sapiens interferon regulatory factor 1 (IRF1), mRNA.
IFIH1 / 4.15 ± 0.60 / 1.58E-02 / NM_022168.2 / Homo sapiens interferon induced with helicase C domain 1 (IFIH1), mRNA.
IFIT1 / 4.14 ± 0.53 / 2.93E-03 / NM_001548.2 / Homo sapiens interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), transcript variant 2, mRNA.
PRIC285 / 4.09 ± 0.26 / 2.36E-03 / NM_033405.2 / Homo sapiens peroxisomal proliferator-activated receptor A interacting complex 285 (PRIC285), transcript variant 2, mRNA.
RSAD2 / 3.98 ± 0.25 / 2.96E-03 / NM_080657.3 / Homo sapiens radical S-adenosyl methionine domain containing 2 (RSAD2), mRNA.
IL28A / 3.98 ± 0.39 / 4.48E-03 / NM_172138.1 / Homo sapiens interleukin 28A (interferon, lambda 2) (IL28A), mRNA.
ISG20 / 3.84 ± 0.49 / 6.07E-03 / NM_002201.4 / Homo sapiens interferon stimulated exonuclease gene 20kDa (ISG20), mRNA.
RTP4 / 3.80 ± 0.30 / 5.67E-03 / NM_022147.2 / Homo sapiens receptor (chemosensory) transporter protein 4 (RTP4), mRNA.
KRT17 / 3.76 ± 0.47 / 1.06E-02 / NM_000422.1 / Homo sapiens keratin 17 (KRT17), mRNA.
STAT2 / 3.69 ± 0.14 / 1.10E-04 / NM_005419.2 / Homo sapiens signal transducer and activator of transcription 2, 113kDa (STAT2), mRNA.
ALDH1A3 / 3.65 ± 0.77 / 3.20E-02 / NM_000693.1 / Homo sapiens aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), mRNA.
IFI44 / 3.64 ± 0.32 / 2.19E-03 / NM_006417.2 / Homo sapiens interferon-induced protein 44 (IFI44), mRNA.
LBA1 / 3.60 ± 0.40 / 3.19E-03 / XM_940627.1 / Homo sapiens lupus brain antigen 1 (LBA1), mRNA.
HLA-A / 3.50 ± 0.12 / 2.94E-04 / NM_002116.5 / Homo sapiens major histocompatibility complex, class I, A (HLA-A), mRNA.
OAS3 / 3.46 ± 0.29 / 5.32E-03 / NM_006187.2 / Homo sapiens 2'-5'-oligoadenylate synthetase 3, 100kDa (OAS3), mRNA.
PARP9 / 3.45 ± 0.12 / 1.77E-04 / NM_031458.1 / Homo sapiens poly (ADP-ribose) polymerase family, member 9 (PARP9), mRNA.
HERC6 / 3.38 ± 0.28 / 5.98E-04 / NM_001013005.1 / Homo sapiens hect domain and RLD 6 (HERC6), transcript variant 1, mRNA.
NCOA7 / 3.36 ± 0.28 / 3.96E-03 / NM_181782.2 / Homo sapiens nuclear receptor coactivator 7 (NCOA7), mRNA.
CYP1A1 / 3.34 ± 0.44 / 1.70E-02 / NM_000499.2 / Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1), mRNA.
LAMP3 / 3.33 ± 0.12 / 8.24E-04 / NM_014398.2 / Homo sapiens lysosomal-associated membrane protein 3 (LAMP3), mRNA.
NMI / 3.21 ± 0.84 / 5.34E-02 / NM_004688.1 / Homo sapiens N-myc (and STAT) interactor (NMI), mRNA.
DHRS3 / 3.20 ± 0.72 / 4.96E-02 / NM_004753.4 / Homo sapiens dehydrogenase/reductase (SDR family) member 3 (DHRS3), mRNA.
CMPK2 / 3.14 ± 0.36 / 1.13E-02 / NM_207315.1 / Homo sapiens cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial (CMPK2), nuclear gene encoding mitochondrial protein, mRNA.
LGALS9 / 3.13 ± 0.07 / 5.09E-04 / NM_009587.2 / Homo sapiens lectin, galactoside-binding, soluble, 9 (LGALS9), transcript variant 1, mRNA.
DDX60 / 3.09 ± 0.13 / 2.22E-04 / NM_017631.3 / Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 (DDX60), mRNA.
TAP2 / 3.06 ± 0.14 / 2.23E-03 / NM_000544.3 / Homo sapiens transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1, mRNA.
COL5A1 / 3.05 ± 0.26 / 4.62E-03 / NM_000093.2 / Homo sapiens collagen, type V, alpha 1 (COL5A1), mRNA.
MDK / 3.01 ± 0.05 / 2.57E-04 / NM_001012334.1 / Homo sapiens midkine (neurite growth-promoting factor 2) (MDK), transcript variant 1, mRNA.
CLDN1 / 2.98 ± 0.26 / 6.12E-03 / NM_021101.3 / Homo sapiens claudin 1 (CLDN1), mRNA.
GBP4 / 2.97 ± 0.39 / 1.44E-02 / NM_052941.2 / Homo sapiens guanylate binding protein 4 (GBP4), mRNA.
DDX58 / 2.96 ± 0.15 / 3.90E-04 / NM_014314.2 / Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58), mRNA.
SAMD9L / 2.92 ± 0.16 / 2.78E-03 / NM_152703.2 / Homo sapiens sterile alpha motif domain containing 9-like (SAMD9L), mRNA.
DUSP19 / 2.90 ± 0.74 / 2.53E-02 / NM_080876.2 / Homo sapiens dual specificity phosphatase 19 (DUSP19), mRNA.
PLEKHA4 / 2.85 ± 0.24 / 1.86E-03 / NM_020904.1 / Homo sapiens pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 (PLEKHA4), mRNA.
MVP / 2.83 ± 0.16 / 2.36E-03 / NM_017458.2 / Homo sapiens major vault protein (MVP), transcript variant 1, mRNA.
PLSCR1 / 2.80 ± 0.54 / 3.68E-02 / NM_021105.1 / Homo sapiens phospholipid scramblase 1 (PLSCR1), mRNA.
TAGLN / 2.79 ± 0.02 / 5.45E-05 / NM_001001522.1 / Homo sapiens transgelin (TAGLN), transcript variant 1, mRNA.
UGT1A6 / 2.78 ± 0.62 / 4.71E-02 / NM_001072.2 / Homo sapiens UDP glucuronosyltransferase 1 family, polypeptide A6 (UGT1A6), transcript variant 1, mRNA.
BATF2 / 2.76 ± 0.18 / 4.74E-03 / NM_138456.3 / Homo sapiens basic leucine zipper transcription factor, ATF-like 2 (BATF2), mRNA.
SALL4 / 2.75 ± 0.19 / 3.86E-03 / NM_020436.2 / Homo sapiens sal-like 4 (Drosophila) (SALL4), mRNA.
PSMB10 / 2.71 ± 0.01 / 1.73E-05 / NM_002801.2 / Homo sapiens proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10), mRNA.
OPTN / 2.71 ± 0.24 / 8.10E-03 / NM_001008213.1 / Homo sapiens optineurin (OPTN), transcript variant 4, mRNA.
HLA-E / 2.68 ± 0.15 / 2.23E-03 / NM_005516.4 / Homo sapiens major histocompatibility complex, class I, E (HLA-E), mRNA.
SCIN / 2.66 ± 0.19 / 2.18E-03 / NM_033128.1 / Homo sapiens scinderin (SCIN), mRNA.
LOC100129681 / 2.66 ± 0.26 / 1.13E-02 / XM_001726834.1 / PREDICTED: Homo sapiens similar to NPC-A-7 (LOC100129681), mRNA.
FBXO32 / 2.65 ± 0.26 / 1.16E-02 / NM_148177.1 / Homo sapiens F-box protein 32 (FBXO32), transcript variant 2, mRNA.
CEACAM1 / 2.64 ± 0.27 / 1.26E-02 / NM_001024912.1 / Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), transcript variant 2, mRNA.
B2M / 2.63 ± 0.35 / 1.58E-02 / NM_004048.2 / Homo sapiens beta-2-microglobulin (B2M), mRNA.
TRIM21 / 2.62 ± 0.14 / 2.18E-03 / NM_003141.3 / Homo sapiens tripartite motif-containing 21 (TRIM21), mRNA.
AOX1 / 2.62 ± 0.22 / 7.22E-03 / NM_001159.3 / Homo sapiens aldehyde oxidase 1 (AOX1), mRNA.
KIAA1618 / 2.61 ± 0.10 / 1.36E-03 / NM_020954.2 / Homo sapiens KIAA1618 (KIAA1618), mRNA.
TDRD7 / 2.57 ± 0.28 / 8.45E-03 / NM_014290.1 / Homo sapiens tudor domain containing 7 (TDRD7), mRNA.
NFKBIZ / 2.57 ± 0.18 / 3.37E-03 / NM_001005474.1 / Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), transcript variant 2, mRNA.
OGFR / 2.56 ± 0.22 / 2.43E-03 / NM_007346.2 / Homo sapiens opioid growth factor receptor (OGFR), mRNA.
LMCD1 / 2.56 ± 0.45 / 3.86E-02 / NM_014583.2 / Homo sapiens LIM and cysteine-rich domains 1 (LMCD1), mRNA.
TRIM22 / 2.54 ± 0.29 / 7.52E-03 / NM_006074.2 / Homo sapiens tripartite motif-containing 22 (TRIM22), mRNA.
GPRC5A / 2.54 ± 0.43 / 1.73E-02 / NM_003979.3 / Homo sapiens G protein-coupled receptor, family C, group 5, member A (GPRC5A), mRNA.
IRF7 / 2.52 ± 0.12 / 8.82E-04 / NM_004029.2 / Homo sapiens interferon regulatory factor 7 (IRF7), transcript variant b, mRNA.
TGFB2 / 2.51 ± 0.48 / 4.31E-02 / NM_003238.1 / Homo sapiens transforming growth factor, beta 2 (TGFB2), mRNA.
DHX58 / 2.48 ± 0.31 / 2.11E-02 / NM_024119.1 / Homo sapiens DEXH (Asp-Glu-X-His) box polypeptide 58 (DHX58), mRNA.
UNC93B1 / 2.48 ± 0.32 / 5.45E-03 / NM_030930.2 / Homo sapiens unc-93 homolog B1 (C. elegans) (UNC93B1), mRNA.
BST2 / 2.46 ± 0.05 / 4.00E-04 / NM_004335.2 / Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA.
ABCA1 / 2.45 ± 0.09 / 1.63E-03 / NM_005502.2 / Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), mRNA.
TRIM5 / 2.44 ± 0.22 / 5.96E-03 / NM_033092.1 / Homo sapiens tripartite motif-containing 5 (TRIM5), transcript variant gamma, mRNA.
SP110 / 2.44 ± 0.16 / 1.01E-03 / NM_080424.1 / Homo sapiens SP110 nuclear body protein (SP110), transcript variant c, mRNA.
TFPI / 2.43 ± 0.32 / 1.32E-02 / NM_001032281.1 / Homo sapiens tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI), transcript variant 1, mRNA.
IFITM3 / 2.43 ± 0.11 / 2.74E-03 / NM_021034.1 / Homo sapiens interferon induced transmembrane protein 3 (1-8U) (IFITM3), mRNA.
CRISPLD2 / 2.42 ± 0.14 / 2.77E-03 / NM_031476.1 / Homo sapiens cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2), mRNA.
SLC2A6 / 2.40 ± 0.36 / 2.61E-02 / NM_017585.2 / Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6), mRNA.
LOC643384 / 2.39 ± 0.19 / 8.82E-03 / XR_016363.2 / PREDICTED: Homo sapiens hypothetical LOC643384 (LOC643384), mRNA.
CXCL10 / 2.39 ± 0.14 / 1.43E-03 / NM_001565.1 / Homo sapiens chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA.
STAT1 / 2.39 ± 0.12 / 9.63E-04 / NM_139266.1 / Homo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha, mRNA.
DDX60L / 2.37 ± 0.10 / 1.87E-03 / NM_001012967.1 / Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like (DDX60L), mRNA.
CACNG6 / 2.36 ± 0.10 / 2.46E-03 / NM_145814.1 / Homo sapiens calcium channel, voltage-dependent, gamma subunit 6 (CACNG6), transcript variant 1, mRNA.
RNU1-5 / 2.35 ± 0.38 / 1.32E-02 / NR_004400.1 / Homo sapiens RNA, U1 small nuclear 5 (RNU1-5), small nuclear RNA.
ZFYVE26 / 2.34 ± 0.21 / 2.71E-03 / NM_015346.2 / Homo sapiens zinc finger, FYVE domain containing 26 (ZFYVE26), mRNA.
EPAS1 / 2.34 ± 0.18 / 3.23E-03 / NM_001430.3 / Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA.
ZMYND15 / 2.34 ± 0.23 / 1.25E-02 / NM_032265.1 / Homo sapiens zinc finger, MYND-type containing 15 (ZMYND15), transcript variant 2, mRNA.
LOC100128274 / 2.34 ± 0.05 / 2.05E-04 / XM_001725558.1 / PREDICTED: Homo sapiens hypothetical protein LOC100128274 (LOC100128274), mRNA.
HCG4 / 2.34 ± 0.31 / 1.20E-02 / NR_002139.1 / Homo sapiens HLA complex group 4 (HCG4), non-coding RNA.
HSH2D / 2.34 ± 0.16 / 5.46E-03 / NM_032855.2 / Homo sapiens hematopoietic SH2 domain containing (HSH2D), mRNA.
RNU1G2 / 2.33 ± 0.26 / 1.13E-02 / NR_004426.1 / Homo sapiens RNA, U1G2 small nuclear (RNU1G2), small nuclear RNA.
LOXL4 / 2.33 ± 0.26 / 1.67E-02 / NM_032211.6 / Homo sapiens lysyl oxidase-like 4 (LOXL4), mRNA.
RNU1-3 / 2.33 ± 0.30 / 5.32E-03 / NR_004408.1 / Homo sapiens RNA, U1 small nuclear 3 (RNU1-3), small nuclear RNA.
BIRC3 / 2.32 ± 0.08 / 3.56E-04 / NM_182962.1 / Homo sapiens baculoviral IAP repeat-containing 3 (BIRC3), transcript variant 2, mRNA.
DCDC2 / 2.32 ± 0.34 / 1.58E-02 / NM_016356.1 / Homo sapiens doublecortin domain containing 2 (DCDC2), mRNA.
RAB32 / 2.32 ± 0.12 / 4.34E-03 / NM_006834.2 / Homo sapiens RAB32, member RAS oncogene family (RAB32), mRNA.
IFI27 / 2.31 ± 0.14 / 1.24E-03 / NM_005532.3 / Homo sapiens interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, mRNA.
NT5E / 2.31 ± 0.57 / 8.00E-02 / NM_002526.1 / Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), mRNA.
TMEM62 / 2.30 ± 0.06 / 3.02E-04 / NM_024956.3 / Homo sapiens transmembrane protein 62 (TMEM62), mRNA.
TNFRSF21 / 2.28 ± 0.41 / 2.77E-02 / NM_014452.3 / Homo sapiens tumor necrosis factor receptor superfamily, member 21 (TNFRSF21), mRNA.
TGFBI / 2.26 ± 0.30 / 7.42E-03 / NM_000358.1 / Homo sapiens transforming growth factor, beta-induced, 68kDa (TGFBI), mRNA.
DRAM1 / 2.26 ± 0.08 / 4.61E-04 / NM_018370.1 / Homo sapiens DNA-damage regulated autophagy modulator 1 (DRAM1), mRNA.
MT2A / 2.26 ± 0.13 / 3.61E-03 / NM_005953.2 / Homo sapiens metallothionein 2A (MT2A), mRNA.
LOC440353 / 2.25 ± 0.24 / 1.85E-02 / NR_002603.1 / Homo sapiens nuclear pore complex interacting protein pseudogene (LOC440353), non-coding RNA.
TGM2 / 2.24 ± 0.06 / 7.48E-04 / NM_198951.1 / Homo sapiens transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 2, mRNA.
FAM46A / 2.24 ± 0.11 / 1.38E-03 / NM_017633.1 / Homo sapiens family with sequence similarity 46, member A (FAM46A), mRNA.
RND3 / 2.24 ± 0.18 / 5.63E-03 / NM_005168.3 / Homo sapiens Rho family GTPase 3 (RND3), mRNA.
LOC100132247 / 2.23 ± 0.22 / 9.44E-03 / NM_001135865.1 / Homo sapiens similar to Uncharacterized protein KIAA0220 (LOC100132247), mRNA.
LOC648526 / 2.23 ± 0.21 / 1.06E-02 / XM_937579.1 / PREDICTED: Homo sapiens similar to epiplakin 1 (LOC648526), mRNA.
SELL / 2.22 ± 0.08 / 1.97E-03 / NM_000655.2 / Homo sapiens selectin L (SELL), mRNA.
LOC440348 / 2.22 ± 0.19 / 1.19E-02 / NM_001018059.2 / Homo sapiens similar to nuclear pore complex interacting protein (LOC440348), mRNA.
C3orf59 / 2.22 ± 0.24 / 1.46E-02 / NM_178496.2 / Homo sapiens chromosome 3 open reading frame 59 (C3orf59), mRNA.
TRAFD1 / 2.21 ± 0.10 / 1.30E-03 / NM_006700.1 / Homo sapiens TRAF-type zinc finger domain containing 1 (TRAFD1), mRNA.
LOC729090 / 2.20 ± 0.54 / 3.94E-02 / XR_015449.2 / PREDICTED: Homo sapiens similar to Eukaryotic translation elongation factor 1 alpha 1 (LOC729090), mRNA.
SP100 / 2.20 ± 0.06 / 5.11E-04 / NM_001080391.1 / Homo sapiens SP100 nuclear antigen (SP100), transcript variant 1, mRNA.
MX1 / 2.20 ± 0.19 / 5.41E-03 / NM_002462.2 / Homo sapiens myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1), mRNA.
STC2 / 2.19 ± 0.09 / 1.23E-03 / NM_003714.2 / Homo sapiens stanniocalcin 2 (STC2), mRNA.
HLA-G / 2.19 ± 0.48 / 6.95E-02 / NM_002127.3 / Homo sapiens HLA-G histocompatibility antigen, class I, G (HLA-G), mRNA.
ACTG2 / 2.19 ± 0.03 / 6.52E-05 / NM_001615.3 / Homo sapiens actin, gamma 2, smooth muscle, enteric (ACTG2), mRNA.
IFITM2 / 2.18 ± 0.07 / 7.25E-04 / NM_006435.1 / Homo sapiens interferon induced transmembrane protein 2 (1-8D) (IFITM2), mRNA.
PMP22 / 2.18 ± 0.10 / 9.70E-04 / NM_153321.1 / Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 2, mRNA.
LOC728457 / 2.18 ± 0.18 / 4.12E-03 / XR_037027.1 / PREDICTED: Homo sapiens misc_RNA (LOC728457), miscRNA.
C4orf19 / 2.17 ± 0.18 / 1.12E-02 / NM_018302.1 / Homo sapiens chromosome 4 open reading frame 19 (C4orf19), mRNA.
LYN / 2.17 ± 0.16 / 2.77E-03 / NM_002350.1 / Homo sapiens v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN), mRNA.
APOD / 2.17 ± 0.43 / 5.62E-02 / NM_001647.2 / Homo sapiens apolipoprotein D (APOD), mRNA.
LOC728888 / 2.16 ± 0.14 / 2.81E-03 / XM_930046.1 / PREDICTED: Homo sapiens similar to Protein KIAA0220 (LOC728888), mRNA.
ANKRD1 / 2.15 ± 0.26 / 2.37E-02 / NM_014391.2 / Homo sapiens ankyrin repeat domain 1 (cardiac muscle) (ANKRD1), mRNA.
MOV10 / 2.14 ± 0.20 / 1.05E-02 / NM_020963.1 / Homo sapiens Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), mRNA.
PSCD1 / 2.12 ± 0.17 / 6.98E-03 / NM_017456.1 / Homo sapiens pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1) (PSCD1), transcript variant 2, mRNA.
LOC440341 / 2.12 ± 0.08 / 1.29E-03 / XM_932044.1 / PREDICTED: Homo sapiens similar to nuclear pore complex interacting protein, transcript variant 4 (LOC440341), mRNA.
IL10 / 2.11 ± 0.26 / 1.59E-02 / NM_000572.2 / Homo sapiens interleukin 10 (IL10), mRNA.
CXCL16 / 2.11 ± 0.22 / 5.90E-03 / XM_931373.1 / Homo sapiens chemokine (C-X-C motif) ligand 16 (CXCL16), mRNA.
IFI30 / 2.10 ± 0.25 / 5.97E-03 / NM_006332.3 / Homo sapiens interferon, gamma-inducible protein 30 (IFI30), mRNA.
LOC645452 / 2.10 ± 0.42 / 1.67E-02 / XM_939733.2 / PREDICTED: Homo sapiens similar to hCG1782414 (LOC645452), mRNA.
SPATS2L / 2.10 ± 0.28 / 1.80E-02 / NM_015535.1 / Homo sapiens spermatogenesis associated, serine-rich 2-like (SPATS2L), transcript variant 2, mRNA.
PSG4 / 2.09 ± 0.24 / 1.53E-02 / NM_002780.3 / Homo sapiens pregnancy specific beta-1-glycoprotein 4 (PSG4), transcript variant 1, mRNA.
TRIM56 / 2.08 ± 0.30 / 1.94E-02 / NM_030961.1 / Homo sapiens tripartite motif-containing 56 (TRIM56), mRNA.
BATF / 2.08 ± 0.24 / 2.35E-02 / NM_006399.2 / Homo sapiens basic leucine zipper transcription factor, ATF-like (BATF), mRNA.
TAPBP / 2.08 ± 0.04 / 5.44E-04 / NM_172209.1 / Homo sapiens TAP binding protein (tapasin) (TAPBP), transcript variant 3, mRNA.
LAP3 / 2.07 ± 0.25 / 1.88E-02 / NM_015907.2 / Homo sapiens leucine aminopeptidase 3 (LAP3), mRNA.
ZFP36L1 / 2.07 ± 0.30 / 3.59E-02 / NM_004926.2 / Homo sapiens zinc finger protein 36, C3H type-like 1 (ZFP36L1), mRNA.
[Unannotated] / 2.07 ± 0.18 / 1.15E-02 / Hs.570988 / Homo sapiens primary neuroblastoma cDNA, clone:Nbla10111, full insert sequence
SNAI2 / 2.07 ± 0.22 / 1.71E-02 / NM_003068.3 / Homo sapiens snail homolog 2 (Drosophila) (SNAI2), mRNA.
PAPSS2 / 2.07 ± 0.25 / 1.48E-02 / NM_004670.3 / Homo sapiens 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2), transcript variant 1, mRNA.
REC8 / 2.07 ± 0.22 / 1.33E-02 / NM_005132.1 / Homo sapiens REC8 homolog (yeast) (REC8), transcript variant 1, mRNA.
MYH9 / 2.06 ± 0.07 / 1.82E-03 / NM_002473.3 / Homo sapiens myosin, heavy chain 9, non-muscle (MYH9), mRNA.
LOC728809 / 2.06 ± 0.77 / 9.35E-02 / XM_001719546.1 / PREDICTED: Homo sapiens hypothetical LOC728809 (LOC728809), mRNA.
TRIM31 / 2.06 ± 0.06 / 7.03E-04 / NM_007028.3 / Homo sapiens tripartite motif-containing 31 (TRIM31), mRNA.
LOC440157 / 2.06 ± 0.15 / 7.36E-03 / NM_001013701.1 / Homo sapiens hypothetical gene supported by AK096951; BC066547 (LOC440157), mRNA.
NUB1 / 2.05 ± 0.07 / 5.03E-04 / NM_016118.3 / Homo sapiens negative regulator of ubiquitin-like proteins 1 (NUB1), mRNA.
CDKN2AIPNL / 2.05 ± 0.50 / 6.65E-02 / NM_080656.1 / Homo sapiens CDKN2A interacting protein N-terminal like (CDKN2AIPNL), mRNA.
LPIN1 / 2.04 ± 0.07 / 9.27E-04 / NM_145693.1 / Homo sapiens lipin 1 (LPIN1), mRNA.
PDLIM1 / 2.04 ± 0.23 / 2.06E-02 / NM_020992.2 / Homo sapiens PDZ and LIM domain 1 (PDLIM1), mRNA.
MT1A / 2.04 ± 0.05 / 9.64E-04 / NM_005946.2 / Homo sapiens metallothionein 1A (MT1A), mRNA.
OSBPL7 / 2.04 ± 0.13 / 5.45E-03 / NM_145798.2 / Homo sapiens oxysterol binding protein-like 7 (OSBPL7), transcript variant 1, mRNA.
EIF2AK2 / 2.03 ± 0.02 / 1.07E-04 / NM_002759.1 / Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), mRNA.
C10orf81 / 2.02 ± 0.13 / 3.32E-03 / NM_024889.3 / Homo sapiens chromosome 10 open reading frame 81 (C10orf81), mRNA.
TPM2 / 2.02 ± 0.07 / 2.12E-03 / NM_003289.3 / Homo sapiens tropomyosin 2 (beta) (TPM2), transcript variant 2, mRNA.
RNU1A3 / 2.02 ± 0.13 / 3.27E-03 / NR_004430.1 / Homo sapiens RNA, U1A3 small nuclear (RNU1A3), small nuclear RNA.
SIK1 / 2.02 ± 0.08 / 1.13E-03 / NM_173354.2 / Homo sapiens salt-inducible kinase 1 (SIK1), mRNA.
TAPBPL / 2.01 ± 0.17 / 7.95E-03 / NM_018009.3 / Homo sapiens TAP binding protein-like (TAPBPL), mRNA.
TP53INP1 / 2.01 ± 0.21 / 1.29E-02 / NM_033285.2 / Homo sapiens tumor protein p53 inducible nuclear protein 1 (TP53INP1), mRNA.
KIAA0513 / 2.01 ± 0.09 / 1.49E-03 / NM_014732.2 / Homo sapiens KIAA0513 (KIAA0513), mRNA.
HIST1H2BJ / 2.00 ± 0.14 / 7.58E-03 / NM_021058.3 / Homo sapiens histone cluster 1, H2bj (HIST1H2BJ), mRNA.
[Unannotated] / 2.00 ± 0.11 / 1.43E-03 / Hs.201441 / Homo sapiens cDNA FLJ11076 fis, clone PLACE1005077

Supplementary Table S1B. Transcripts downregulated ≥ 2-fold following miR-34b overexpression in MCF-7 cells.

Symbol / Fold Change ± SD / P-value / Accession Number / Definition
MTSS1 / -2.01 ± 0.01 / 1.14E-03 / NM_014751.2 / Homo sapiens metastasis suppressor 1 (MTSS1), mRNA.
LOC729679 / -2.02 ± 0.03 / 1.81E-03 / XR_015990.2 / PREDICTED: Homo sapiens misc_RNA (LOC729679), miscRNA.
AFAP1L2 / -2.03 ± 0.03 / 9.04E-03 / NM_001001936.1 / Homo sapiens actin filament associated protein 1-like 2 (AFAP1L2), transcript variant 1, mRNA.
KLK11 / -2.04 ± 0.04 / 8.35E-03 / NM_006853.2 / Homo sapiens kallikrein-related peptidase 11 (KLK11), transcript variant 2, mRNA.
LOC100132673 / -2.05 ± 0.02 / 2.81E-03 / XR_039018.1 / PREDICTED: Homo sapiens misc_RNA (LOC100132673), miscRNA.
MGP / -2.05 ± 0.03 / 5.77E-03 / NM_000900.2 / Homo sapiens matrix Gla protein (MGP), mRNA.
KIAA1324 / -2.06 ± 0.07 / 3.28E-02 / NM_020775.2 / Homo sapiens KIAA1324 (KIAA1324), mRNA.
[Unannotated] / -2.08 ± 0.02 / 3.91E-03 / Hs.567759 / Homo sapiens cDNA FLJ38153 fis, clone DFNES1000083
C9orf152 / -2.10 ± 0.06 / 2.17E-02 / NM_001012993.1 / Homo sapiens chromosome 9 open reading frame 152 (C9orf152), mRNA.
ASCL1 / -2.13 ± 0.03 / 5.83E-03 / NM_004316.2 / Homo sapiens achaete-scute complex homolog 1 (Drosophila) (ASCL1), mRNA.
S100A7 / -2.24 ± 0.01 / 1.07E-04 / NM_002963.2 / Homo sapiens S100 calcium binding protein A7 (S100A7), mRNA.
PGM1 / -2.25 ± 0.08 / 3.93E-02 / NM_002633.2 / Homo sapiens phosphoglucomutase 1 (PGM1), mRNA.
MYB / -2.31 ± 0.05 / 1.58E-02 / NM_005375.2 / Homo sapiens v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, mRNA.
SHISA2 / -2.32 ± 0.03 / 1.89E-03 / NM_001007538.1 / Homo sapiens shisa homolog 2 (Xenopus laevis) (SHISA2), mRNA.
AK3L1 / -2.34 ± 0.07 / 3.63E-02 / NM_013410.2 / Homo sapiens adenylate kinase 3-like 1 (AK3L1), nuclear gene encoding mitochondrial protein, transcript variant 6, mRNA.
TXNDC12 / -2.36 ± 0.03 / 1.36E-03 / NM_015913.2 / Homo sapiens thioredoxin domain containing 12 (endoplasmic reticulum) (TXNDC12), mRNA.
LOC399942 / -2.38 ± 0.07 / 3.71E-02 / XM_934471.1 / PREDICTED: Homo sapiens similar to Tubulin alpha-2 chain (Alpha-tubulin 2), transcript variant 5 (LOC399942), mRNA.
HS3ST3A1 / -2.38 ± 0.04 / 2.98E-03 / NM_006042.1 / Homo sapiens heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 (HS3ST3A1), mRNA.
CRABP1 / -2.39 ± 0.03 / 4.31E-03 / NM_004378.1 / Homo sapiens cellular retinoic acid binding protein 1 (CRABP1), mRNA.
[Unannotated] / -2.43 ± 0.04 / 1.01E-02 / Hs.296031 / Homo sapiens cDNA clone IMAGE:5262734
TFF3 / -2.54 ± 0.05 / 2.27E-02 / NM_003226.2 / Homo sapiens trefoil factor 3 (intestinal) (TFF3), mRNA.
IL20 / -2.75 ± 0.01 / 9.49E-05 / NM_018724.3 / Homo sapiens interleukin 20 (IL20), mRNA.
BNIP3 / -2.77 ± 0.08 / 5.13E-02 / NM_004052.2 / Homo sapiens BCL2/adenovirus E1B 19kDa interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA.
ALDOC / -2.92 ± 0.06 / 3.06E-02 / NM_005165.2 / Homo sapiens aldolase C, fructose-bisphosphate (ALDOC), mRNA.
KRTDAP / -2.95 ± 0.02 / 3.38E-03 / NM_207392.1 / Homo sapiens keratinocyte differentiation-associated protein (KRTDAP), mRNA.
NDRG1 / -2.95 ± 0.08 / 5.36E-02 / NM_006096.2 / Homo sapiens N-myc downstream regulated gene 1 (NDRG1), mRNA.
IGFBP5 / -3.00 ± 0.05 / 2.60E-02 / NM_000599.2 / Homo sapiens insulin-like growth factor binding protein 5 (IGFBP5), mRNA.
ACO1 / -3.15 ± 0.03 / 2.70E-03 / NM_002197.1 / Homo sapiens aconitase 1, soluble (ACO1), mRNA.
S100A9 / -3.18 ± 0.04 / 7.84E-03 / NM_002965.2 / Homo sapiens S100 calcium binding protein A9 (calgranulin B) (S100A9), mRNA.
[Unannotated] / -3.77 ± 0.02 / 6.46E-03 / Hs.10862 / Homo sapiens cDNA: FLJ23313 fis, clone HEP11919
S100A8 / -4.41 ± 0.01 / 1.18E-03 / NM_002964.3 / Homo sapiens S100 calcium binding protein A8 (S100A8), mRNA.