Supplementary Table 1: Questions for Laparoscopic Liver Resection (LLR) and Their Working

Supplementary Table 1: Questions for laparoscopic liver resection (LLR) and their working groups

Comparative outcomes, value, safety

Q1What are the comparative short-term outcomes of LLR vs. open liver resection(OLR)? (minor and major)

Daniel Cherqui*, Olivier Scatton, Mohammad Abu Hilal, Luca Aldrighetti, Juan Pekolj, Kuo-Hsin Chen, Hironori Kaneko

Q2What are the comparative long-term outcomes of LLR vs. OLR? (minor and major)

David Geller*, Paulo Herman, Giulio Belli, Bjørn Edwin

Q3What are the comparative cost implications of LLR vs. OLR?(minor and major)

Horacio Asbun*, Sean Cleary, Ho-Seong Han

Q4What are the comparative pain control and QOL outcomes for LLR vs. OLR?(minor and major)

Nicholas O'Rourke*, Mohammed Abu Hilal, Minoru Tanabe

Robotic and donor hepatectomy

Q5 What is the role of robotic hepatectomy?

Allan Tsung*, Gi Hong Choi, Chung-Ngai Tang

Q6Is LLR applicable to donor hepatectomy?

Roberto Troisi*, Go Wakabayashi, Olivier Scatton, Daniel Cherqui

Randomized controlled trial (RCT)

Q7Are RCTs feasible for LLR?

Ronald Van Dam*, Bjørn Edwin, David Kwon

Spread, difficulty, alternatives

Q8 What is the spread of LLR?

Ho-Seong Han*, Michael R. Schön, Horacio J Asbun

Q9 What determines the difficulty of LLR?

Minoru Tanabe*, Luca Aldrighetti, Roberto Troisi

Q10 What is the role of HALS and the hybrid method?

Alan Koffron*, Joseph Buell, Go Wakabayashi

Techniques

Q11 What has changed in the concept of liver resection?

Olivier Soubrane*, Go Wakabayashi, Ibrahim Dagher

Q12 What are the essentials of bleeding control in LLR?

Ibrahim Dagher*, Nicholas O'Rourke, Atsushi Sugioka, Ronald Van Dam

Q13What is the best technique for parenchymal transection?

Hironori Kaneko*, Joseph Buell, Xiujun Cai, Sean P. Cleary

Q14What kind of energy devices should be used for LLR?

Brice Gayet*, Giulio Belli, Juan Pekolj, Olivier Scatton

Q15What is the best approach to the hilar structures（individual or Glissonian approach）?

Marcel Machado*, Astushi Sugioka, Olivier Soubrane

Q16Is anatomical resection preferable for LLR?

Go Wakabayashi*, David Kwon, Michael R. Schön

Simulation, navigation

Q17What is the role of simulation and navigation in LLR?

Patrick Pessaux*, Brice Gayet, Allan Tsung

*Primary author

Supplementary Table 2: Questions (Q1-7) Covered by Jury and Jury Assignments

Q1 Short term outcomes Barkun, Jarnagin

Q2 Long term outcomes Clavien, Strong

Q3 Cost Jagannath, Yamamoto

Q4 Pain control and QOL Kokudo, Lo

Q5 Robotic hepatectomy All

Q6 Donor Hepatectomy Kokudo, Strong

Q7 Are RCT feasible in this areaAll