Supplementary Table 1. Genotype and Allele Frequencies of COL1A1 Gene -1997(T>G), -1363
Supplementary Table 1. Genotype and allele frequencies of COL1A1 gene -1997(T>G), -1363（G>C） in liver cirrhosis with different Child-pugh score
Polymorphisms / genotypeor allele / Grade (A+B)
n=59(%) / Grade C
n=49(%) / P value
-1997 / genotype / GG 28 (0.475)
GT 22 ( 0.373)
TT 9 (0.152) / GG 26 (0.531)
GT 19 (0.388)
TT 4 (0.081) / 0.5216
Allele / G 78 (0.724)
T 40 (0.276) / G 71 (0.724)
T 27 (0.276) / 0.3153
-1363 / genotype / CC 26 (0.433)
CG 24 (0.400)
GG 10 (0.167) / CC 18 (0.367)
CG 25 (0.510)
GG 6 (0.123) / 0.5019
Allele / C 76 (0.633)
G 44 (0.367) / C 61 (0.622)
G 37 (0.378) / 0.8686
Supplementary Table 2. Comparison of estimated haplotype frequencies among different Child-pugh score
-1997 / -1363 / Grade A+B / Grade C / P value
1 / Ｇ / C / 68(0.572) / 61(0.622) / 0.4897
2 / G / G / 11(0.089) / 10(0.102) / 0.6329
3 / T / C / 0(0.055) / 6(0.000) / -
4 / T / T / 33(0.284) / 27(0.276) / 0.8329