Supplemental Table A - Selected features of ALCL cases in patients with breast implants

Source (case) / Characteristics / Cancer History / Affected Implant
Age / Sex / Side / Prior non ALCLcancer (side) / Yrs toALCL / Prior
ALCL / Prior lymphoma or LCL / Surface / Cover / Type / Manufacturer/ Model
Do / 74 / F / R / Breast ca (L) / 6 / N/R / N/R / N/R / N/R / Silicone / N/R
Hanson / 44 / F / R / N/R / N/A / N/R / N/R / Textured / N/R / Saline / N/R
Thompson / 45 / F / N/R / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Alexander / 52 / F / R / N/R / N/A / N/R / N/R / N/R / N/R / N/R / N/R
Carty / 57 / F / L, R / No / N/A / No / No / Textured / N/R / Saline / McGhan style 168 Biocell
Lazzeri / 58 / F / R / N/R / N/A / N/R / N/R / Smooth / N/R / Silicone / Inamed McGhan
Lechner / 42 / F / R / N/R / N/A / N/R / N/R / N/R / Silicone / Saline / Nagor SFX-HP250
Popplewell / 49 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Popplewell / 41 / F / N/R / N/R / N/A / N/R / N/R / N/R / N/R / N/R / N/R
Popplewell / 62 / F / R / N/R / N/A / N/R / N/R / N/R / N/R / N/R / N/R
Popplewell / 54 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / N/R / N/R
Popplewell / 41 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Popplewell / 32 / F / L / N/R / N/A / N/R / N/R / Textured / N/R / N/R / McGhan
Aladily / 47 / F / R / DCIS (N/R) / N/R / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 60 / F / R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / Silicone / N/R
Aladily / 65 / F / L / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 68 / F / L / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / Silicone / N/R
Aladily / 39 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 54 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 46 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 63 / F / R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 63 / F / R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / N/R / N/R
Aladily / 65 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 63 / F / R / Breast ca (L) / 7 / N/R / Lymphomatoid papulosis / N/R / N/R / Saline / N/R
Aladily / 47 / F / R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / Saline / N/R
Aladily / 57 / F / R / N/R / N/A / N/R / N/R / N/R / N/R / Silicone / N/R
Largent / 72 / N/R / R / Breast ca (R, L) / 27 / N/R / N/R / Smooth / N/R / N/R / Allergan
Largent / 53 / N/R / R / Breast ca (L) / 15 / N/R / N/R / Textured / N/R / N/R / Allergan
Largent / 62 / N/R / L / Breast ca (R) / 10 / N/R / N/R / Textured / N/R / Silicone / Allergan
Lechner / 42 / F / N/R / N/R / N/A / N/R / N/R / Textured / N/R / Saline / Nagor SFX-HP250
Lechner / 43 / F / N/R / N/R / N/A / N/R / N/R / Textured / N/R / Saline / McGhan/Inamed/Allergan
Lechner / 45 / F / N/R / N/R / N/A / N/R / N/R / Textured / N/R / Saline / McGhan/Inamed/Allergan
Lee / 48 / F / L / No / N/A / No / No / Textured / N/R / Saline / N/R
Mies / 46 / F / N/R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / N/R / N/R
Mies / 67 / F / N/R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / N/R / N/R
Mies / 67 / F / N/R / Breast ca (N/R) / N/R / N/R / N/R / N/R / N/R / N/R / N/R
Smith / 33 / F / R / N/R / N/A / N/R / N/R / N/R / Yes / Silicone / Silimed
Taylor / 58 / F / L / N/R / N/A / N/R / N/R / Textured / N/R / Silicone / Inamed
Taylor / 37 / F / R / N/R / N/A / N/R / N/R / Textured / Silicone / Saline / Nagor SFX-HP250
Taylor / 49 / F / R / DCIS (R) / 11 / N/R / N/R / Textured / N/R / Saline / McGhan style 468, Inamed
Taylor / 69 / F / R / N/R / N/A / N/R / N/R / Textured / N/R / Silicone / N/R
Taylor / 54 / F / R / DCIS (R) / 16 / N/R / N/R / Textured / N/R / Silicone / McGhan
Arbelaez / 29 / F / R / N/R / N/A / N/R / N/R / Textured / N/R / N/R / McGhan
Bautista-Quach / 52 / F / Bil / N/R / N/A / N/R / N/R / Textured / N/R / Saline / McGhan
De Silva / 34 / F / R / N/R / N/A / N/R / N/R / Textured / N/R / Silicone / Allergan Inspira
de Torres Olombrada / 51 / F / L / Breast ca (R) / N/R / N/R / N/R / N/R / N/R / N/R / N/R
Farace / 51 / F / R / Breast ca (R) / 10 / N/R / N/R / Textured / No / Silicone / McGhan style 410 MF 27-FF125-375 (Allergan)
George / 67 / F / R / DCIS (affected); comedo carcinoma (L) / 11 / N/R / N/R / Textured / No / Silicone / Allergan Style 153 LOT-273111-MCGHAN-360 CC
Parthasarathy / 43 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Silicone / N/R
Singh / 77 / F / L / N/R / N/A / N/R / N/R / N/R / N/R / Silicone / N/R
Sorensen / 55 / F / L / N/R / N/A / N/R / N/R / Textured / No / Silicone / Allergan Style 150
Talagas / 66 / F / R / Breast ca (R) / 10 / No / N/R / N/R / N/R / Saline / McGhan
Weathers / 44 / F / L / N/R / N/A / N/R / N/R / Textured / N/R / Silicone / CUI Corporation, Allergan
Zakhary / 44 / F / L / DCIS (L and R) / 11 / N/R / N/R / Textured / N/R / Saline / N/R

F=Female

R=Right

L=Left

N/R=Not reported

N/A=Not applicable

DCIS=Ductal carcinoma in situ

LCL=Lymphoma-like condition

Appendix Table A - Selected features of ALCL cases in patients with breast implants (continued)

Source (case) / ALCL Characteristics / Outcomes
Ca in capsule / Seroma / Mass / Stage / ALK / Years of Follow-up / Recurrence / Vital status
Do / Yes / No / Yes / IE / Neg / N/R / N/R / N/R
Hanson / N/R / N/R / Yes / N/R / N/R / N/R / N/R / N/R
Thompson / N/R / Yes / No / N/R / N/R / N/R / N/R / N/R
Alexander / N/R / N/R / N/R / N/R / Neg / 0.58 / Yes / Dead
Carty / N/R / No / Yes / IIE / Neg / 3 / Yes / Dead
Lazzeri / Yes / Yes / No / IE / Neg / 1.75 / No / Alive
Lechner / Yes / Yes / No / IE / Neg / 0.58 / No / Alive
Popplewell / N/R / Yes / N/R / N/R / Neg / N/R / N/R / N/R
Popplewell / Yes / N/R / Yes / N/R / Neg / N/R / N/R / N/R
Popplewell / Yes / Yes / N/R / N/R / Neg / N/R / Yes / N/R
Popplewell / Yes / N/R / N/R / N/R / Neg / 7.5 / No / Alive
Popplewell / Yes / N/R / Yes / N/R / Pos, then Neg / 6 / No / Alive
Popplewell / N/R / Yes / N/R / IE / Neg / N/R / N/R / N/R
Aladily / Yes / Yes / No / IE / Neg / 3.5 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 0.4 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 2 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 1 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 0.5 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 1 / No / Alive
Aladily / Yes / Yes / No / IE / Neg / 2 / No / Alive
Aladily / Yes / Yes / No / IIE / Neg / 3 / Yes / Alive
Aladily / Yes / Yes / No / IE / Neg / N/R / N/R / N/R
Aladily / Yes / Yes / No / IE / Neg / 2 / No / Alive
Aladily / N/R / Yes / Yes / IE / Neg / 12 / N/R / Dead
Aladily / N/R / Yes / Yes / IIE / Neg / 2 / Yes / Dead
Aladily / N/R / Yes / Yes / IIE / Neg / 0.5 / No / Alive
Largent / N/R / N/R / N/R / N/R / N/R / 3 / N/R / Alive
Largent / N/R / N/R / N/R / N/R / N/R / 2 / N/R / Alive
Largent / N/R / N/R / N/R / N/R / N/R / 3 / N/R / Alive
Lechner / N/R / Yes / N/R / N/R / Neg / 3 / No / Alive
Lechner / N/R / Yes / N/R / N/R / Neg / 0.75 / Yes / Dead
Lechner / N/R / Yes / Yes / N/R / Neg / 1.17 / No / Alive
Lee / N/R / Yes / Yes / IIE / Neg / 0.25 / No / Alive
Mies / Yes / Yes / N/R / IE / Neg / 3 / No / Alive
Mies / Yes / Yes / N/R / IE / Neg / 1 / No / Alive
Mies / Yes / Yes / N/R / IE / Neg / 0.58 / No / Alive
Smith / No / Yes / No / IE / Neg / 1 / No / Alive
Taylor / Yes / Yes / Yes / IE / Neg / 2 / Yes / Alive
Taylor / No / Yes / No / IE / Neg / 1.5 / No / Alive
Taylor / No / Yes / No / IE / N/R / 2.5 / Yes / Alive
Taylor / Yes / Yes / N/R / IE / Neg / 2 / No / Alive
Taylor / No / No / Yes / IE / Neg / N/R / No / Alive
Arbelaez / No / Yes / N/R / IE / Neg / N/R / N/R / N/R
Bautista-Quach / Yes / Yes / No / IE / Neg / N/R / No / Alive
De Silva / Yes / Yes / No / IE / Neg / 0.33 / No / Alive
de Torres Olombrada / N/R / Yes / N/R / IE / Neg / N/R / N/R / N/R
Farace / Yes / Yes / Yes / IE / Neg / 2 / No / Alive
George / Yes / Yes / N/R / IE / Neg / N/R / Yes / N/R
Parthasarathy / N/R / N/R / Yes / IIE / Neg / 0.25 / No / Alive
Singh / N/A / N/R / Yes / N/R / Neg / N/R / N/R / N/R
Sorensen / N/R / Yes / N/R / IE / Neg / 1 / No / Alive
Talagas / Yes / Yes / N/R / IE / Neg / N/R / No / Alive
Weathers / No / Yes / N/R / IE / Neg / N/R / No / Alive
Zakhary / Yes / Yes / No / IE / Neg / N/R / N/R / N/R

Key: N/R=Not reported; N/A=Not applicable