SUPPLEMENTAL TABLES
Supplemental Table 1: Description of NF-B Genes
Gene / Description / Gene ID / Chr / RefSeq / Position / Size / RefsCanonical; Activation
AHR / aryl hydrocarbon receptor / 196 / 7 / NM_001621.3 / 17,304,832 / 47,467 / [1, 2]
AKT1 / v-akt murine thymoma viral oncogene homolog 1 / 207 / 14 / NM_001014431.1 / 104,306,731 / 26,394 / [3, 4]
AKT2 / v-akt murine thymoma viral oncogene homolog 2 / 208 / 19 / NM_001626.3 / 45,428,064 / 55,041 / [4-6]
ATM / ataxia telangiectasia mutated / 472 / 11 / NM_000051.3 / 107,598,769 / 146,267 / [7]
AZI2 / 5-azacytidine induced 2 / 64343 / 3 / NM_022461.2 / 28,339,090 / 26,489 / [8, 9]
BCL10 / B-cell CLL/lymphoma 10 / 8915 / 1 / NM_003921.3 / 85,504,047 / 12,124 / [10, 11]
BIRC3 / baculoviral IAP repeat-containing 3 / 330 / 11 / NM_001165.3 / 101,693,404 / 20,271 / [12]
BRCA1 / breast cancer 1, early onset / 672 / 17 / NM_007294.2 / 38,449,840 / 81,154 / [8]
CARD10 / caspase recruitment domain family, member 10 / 29775 / 22 / NM_014550.3 / 36,216,346 / 28,810 / [13, 14]
CARD11 / caspase recruitment domain family, member 11 / 84433 / 7 / NM_032415.3 / 2,912,295 / 137,810 / [15]
CARD14 / caspase recruitment domain family, member 14 / 79092 / 17 / NM_024110.2 / 75,766,876 / 30,570 / [15]
CARD9 / caspase recruitment domain family, member 9 / 64170 / 9 / NM_052813.3 / 138,378,229 / 9,710 / [16]
CASP1 / caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) / 834 / 11 / NM_001223.3 / 104,401,445 / 9,622 / [17]
CASP2 / caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) / 835 / 7 / NM_032982.2 / 142,695,524 / 19,383 / [15]
CASP8 / caspase 8, apoptosis-related cysteine peptidase / 841 / 2 / NM_001228.4 / 201,806,411 / 54,268 / [18-20]
CC2D1A / coiled-coil and C2 domain containing 1A / 54862 / 19 / NM_017721.3 / 13,878,052 / 24,640 / [11]
CD247 / CD247 molecule / 919 / 1 / NM_000734.2 / 165,666,505 / 87,945 / [11]
CD28 / CD28 molecule / 940 / 2 / NM_006139.1 / 204,279,443 / 31,358 / [21]
CD3D / CD3d molecule, delta (CD3-TCR complex) / 915 / 11 / NM_000732.4 / 117,714,999 / 3,670 / [22]
CD3E / CD3e molecule, epsilon (CD3-TCR complex) / 916 / 11 / NM_000733.2 / 117,680,662 / 11,438 / [18]
CD3G / CD3g molecule, gamma (CD3-TCR complex) / 917 / 11 / NM_000073.1 / 117,720,311 / 8,950 / [23]
CDC37 / cell division cycle 37 homolog (S. cerevisiae) / 11140 / 19 / NM_007065.3 / 10,362,809 / 12,462 / [24]
CDK4 / cyclin-dependent kinase 4 / 1019 / 12 / NM_000075.2 / 56,428,270 / 4,161 / [25]
CRADD / CASP2 and RIPK1 domain containing adaptor with death domain / 8738 / 12 / NM_003805.3 / 92,595,282 / 173,381 / [26]
CRP / C-reactive protein, pentraxin-related / 1401 / 1 / NM_000567.2 / 157,948,703 / 2,300 / [27, 28]
CSNK2A2 / casein kinase 2, alpha prime polypeptide / 1459 / 16 / NM_001896.2 / 56,749,312 / 39,971 / [29, 30]
CSNK2B / casein kinase 2, beta polypeptide / 1460 / 6 / NM_001320.5 / 31,741,636 / 4,186 / [31]
ECSIT / ECSIT homolog (Drosophila) / 51295 / 19 / NM_016581.2 / 11,477,744 / 23,186 / [32]
EGF / epidermal growth factor (beta-urogastrone) / 1950 / 4 / NM_001963.2 / 111,053,499 / 99,369 / [33]
EGFR / epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) / 1956 / 7 / NM_005228.3 / 55,054,219 / 188,306 / [33]
EIF2AK2 / eukaryotic translation initiation factor 2-alpha kinase 2 / 5610 / 2 / NM_002759.1 / 37,187,203 / 50,369 / [33]
ERBB2 / v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) / 2064 / 17 / NM_001005862.1 / 35,097,919 / 40,522 / [33]
FADD / Fas (TNFRSF6)-associated via death domain / 8772 / 11 / NM_003824.2 / 69,726,917 / 4,227 / [33]
FRAP1 / FK506 binding protein 12-rapamycin associated protein 1 / 2475 / 1 / NM_004958.2 / 11,089,179 / 155,974 / [8]
HRAS / v-Ha-ras Harvey rat sarcoma viral oncogene homolog / 3265 / 11 / NM_005343.2 / 522,242 / 3,308 / [34]
HSP90AA1 / heat shock protein 90kDa alpha (cytosolic), class A member 1 / 3320 / 14 / NM_001017963.2 / 101,616,828 / 59,011 / [35]
HSP90AA2 / heat shock protein 90kDa alpha (cytosolic), class A member 2 / 3324 / 11 / --- / 27,866,201 / 3,114 / [18]
HSP90AB1 / heat shock protein 90kDa alpha (cytosolic), class B member 1 / 3326 / 6 / NM_007355.2 / 44,322,827 / 6,765 / [18, 36]
IKBKB / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta / 3551 / 8 / NM_001556.1 / 42,247,986 / 61,136 / [37]
IKBKE / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon / 9641 / 1 / NM_014002.2 / 204,710,419 / 26,426 / [38]
IKBKG / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma / 8517 / X / NM_001099856.1 / 153,423,653 / 22,802 / [39, 40]
IL12A / interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) / 3592 / 3 / NM_000882.2 / 161,189,323 / 7,177 / [15]
IL15 / interleukin 15 / 3600 / 4 / NM_000585.2 / 142,777,204 / 96,858 / [18]
IL17A / interleukin 17A / 3605 / 6 / NM_002190.2 / 52,159,144 / 4,251 / [8, 18]
IL18 / interleukin 18 (interferon-gamma-inducing factor) / 3606 / 11 / NM_001562.2 / 111,519,186 / 20,864 / [8, 18]
IL1A / interleukin 1, alpha / 3552 / 2 / NM_000575.3 / 113,247,963 / 11,479 / [11]
IL1B / interleukin 1, beta / 3553 / 2 / NM_000576.2 / 113,303,808 / 7,019 / [41, 42]
IL1R1 / interleukin 1 receptor, type I / 3554 / 2 / NM_000877.2 / 102,136,834 / 25,932 / [14, 43, 44]
IL1R2 / interleukin 1 receptor, type II / 7850 / 2 / NM_004633.3 / 101,974,738 / 36,579 / [45]
IL1RAPL1 / interleukin 1 receptor accessory protein-like 1 / 11141 / X / NM_014271.2 / 28,515,480 / 1,369,281 / [14, 46]
IL1RAPL2 / interleukin 1 receptor accessory protein-like 2 / 26280 / X / NM_017416.1 / 103,697,652 / 1,200,826 / [47]
IL2 / interleukin 2 / 3558 / 4 / NM_000586.3 / 123,592,075 / 5,025 / [18]
IL6 / interleukin 6 (interferon, beta 2) / 3569 / 7 / NM_000600.2 / 22,733,343 / 4,802 / [18]
IL8 / interleukin 8 / 3576 / 4 / NM_000584.2 / 74,825,139 / 3,158 / [18]
ILK / integrin-linked kinase / 3611 / 11 / NM_004517.2 / 6,581,540 / 7,137 / [48, 49]
IRAK1 / interleukin-1 receptor-associated kinase 1 / 3654 / X / NM_001569.3 / 152,929,151 / 9,385 / [49, 50]
IRAK2 / interleukin-1 receptor-associated kinase 2 / 3656 / 3 / NM_001570.3 / 10,181,563 / 78,864 / [51]
IRAK4 / interleukin-1 receptor-associated kinase 4 / 51135 / 12 / NM_016123.1 / 42,439,047 / 29,119 / [52]
KRAS / v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog / 3845 / 12 / NM_004985.3 / 25,249,447 / 45,674 / [53]
LAT / linker for activation of T cells / 27040 / 16 / NM_001014989.1 / 28,903,648 / 5,957 / [53]
LBP / lipopolysaccharide binding protein / 3929 / 20 / NM_004139.2 / 36,408,299 / 30,768 / [53]
LCK / lymphocyte-specific protein tyrosine kinase / 3932 / 1 / NM_005356.3 / 32,489,427 / 34,926 / [53]
LCP2 / lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) / 3937 / 5 / NM_005565.3 / 169,607,666 / 49,734 / [53]
MALT1 / mucosa associated lymphoid tissue lymphoma translocation gene 1 / 10892 / 18 / NM_006785.2 / 54,489,598 / 78,752 / [53]
MAP2K1 / mitogen-activated protein kinase kinase 1 / 5604 / 15 / NM_002755.2 / 64,466,679 / 104,257 / [53]
MAP2K2 / mitogen-activated protein kinase kinase 2 / 5605 / 19 / NM_030662.2 / 4,041,319 / 33,807 / [53]
MAP2K3 / mitogen-activated protein kinase kinase 3 / 5606 / 17 / NM_145109.2 / 21,128,561 / 30,584 / [18, 53]
MAP2K4 / mitogen-activated protein kinase kinase 4 / 6416 / 17 / NM_003010.2 / 11,864,860 / 122,916 / [54]
MAP2K5 / mitogen-activated protein kinase kinase 5 / 5607 / 15 / NM_002757.2 / 65,622,075 / 264,431 / [55]
MAP2K6 / mitogen-activated protein kinase kinase 6 / 5608 / 17 / NM_002758.3 / 64,922,433 / 127,632 / [18]
MAP2K7 / mitogen-activated protein kinase kinase 7 / 5609 / 19 / NM_145185.2 / 7,874,765 / 10,598 / [56]
MAP3K1 / mitogen-activated protein kinase kinase kinase 1 / 4214 / 5 / NM_005921.1 / 56,146,657 / 81,079 / [57]
MAP3K11 / mitogen-activated protein kinase kinase kinase 11 / 4296 / 11 / NM_002419.3 / 65,121,802 / 16,494 / [58]
MAP3K2 / mitogen-activated protein kinase kinase kinase 2 / 10746 / 2 / NM_006609.3 / 127,778,609 / 38,631 / [16]
MAP3K3 / mitogen-activated protein kinase kinase kinase 3 / 4215 / 17 / NM_002401.3 / 59,053,533 / 73,869 / [59]
MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / 6885 / 6 / NM_003188.2 / 91,282,074 / 71,554 / [10]
MAP3K7IP1 / mitogen-activated protein kinase kinase kinase 7 interacting protein 1 / 10454 / 22 / NM_153497.2 / 38,125,705 / 37,373 / [60]
MAP3K7IP2 / mitogen-activated protein kinase kinase kinase 7 interacting protein 2 / 23118 / 6 / NM_015093.2 / 149,680,756 / 93,684 / [43, 60]
MAP3K7IP3 / mitogen-activated protein kinase kinase kinase 7 interacting protein 3 / 257397 / X / NM_152787.3 / 30,755,480 / 61,952 / [61]
MAP3K8 / mitogen-activated protein kinase kinase kinase 8 / 1326 / 10 / NM_005204.2 / 30,762,872 / 27,895 / [62, 63]
MAP4K1 / mitogen-activated protein kinase kinase kinase kinase 1 / 11184 / 19 / NM_007181.4 / 43,770,121 / 30,362 / [64]
MAPK14 / mitogen-activated protein kinase 14 / 1432 / 6 / NM_001315.1 / 36,103,551 / 82,962 / [18]
MAPK8 / mitogen-activated protein kinase 8 / 5599 / 10 / NM_002750.2 / 49,279,693 / 33,496 / [65]
MTDH / metadherin / 92140 / 8 / NM_178812.2 / 98,725,583 / 82,131 / [66]
MYD88 / myeloid differentiation primary response gene (88) / 4615 / 3 / NM_002468.3 / 38,155,009 / 4,508 / [67]
NCAM1 / neural cell adhesion molecule 1 / 4684 / 11 / NM_000615.5 / 112,337,205 / 317,163 / [68]
NOD1 / nucleotide-binding oligomerization domain containing 1 / 10392 / 7 / NM_006092.1 / 30,430,675 / 54,115 / [33, 69]
NOD2 / nucleotide-binding oligomerization domain containing 2 / 64127 / 16 / NM_022162.1 / 49,288,551 / 35,937 / [33, 69]
NRK / Nik related kinase / 203447 / X / NM_198465.2 / 104,953,192 / 136,066 / [33, 69]
PDPK1 / 3-phosphoinositide dependent protein kinase-1 / 5170 / 16 / NM_002613.3 / 2,527,971 / 65,219 / [70]
PELI1 / pellino homolog 1 (Drosophila) / 57162 / 2 / NM_020651.2 / 64,173,499 / 19,488 / [71, 72]
PELI2 / pellino homolog 2 (Drosophila) / 57161 / 14 / NM_021255.2 / 55,654,846 / 182,938 / Extension to tcrs from [73, 74]
PELI3 / pellino homolog 3 (Drosophila) / 246330 / 11 / NM_145065.2 / 65,990,912 / 10,472 / Extension to tcrs from [73]
PIK3CA / phosphoinositide-3-kinase, catalytic, alpha polypeptide / 5290 / 3 / NM_006218.2 / 180,349,005 / 86,189 / Extension to tcrs from [73]
PIK3CB / phosphoinositide-3-kinase, catalytic, beta polypeptide / 5291 / 3 / NM_006219.1 / 139,856,921 / 103,954 / [75]
PIK3CG / phosphoinositide-3-kinase, catalytic, gamma polypeptide / 5294 / 7 / NM_002649.2 / 106,293,160 / 41,668 / [76]
PIK3R1 / phosphoinositide-3-kinase, regulatory subunit 1 (alpha) / 5295 / 5 / NM_181523.1 / 67,558,218 / 75,187 / [77]
PLCG1 / phospholipase C, gamma 1 / 5335 / 20 / NM_002660.2 / 39,199,575 / 38,196 / [78]
PRKACA / protein kinase, cAMP-dependent, catalytic, alpha / 5566 / 19 / NM_002730.3 / 14,063,500 / 26,059 / [37, 79]
PRKACB / protein kinase, cAMP-dependent, catalytic, beta / 5567 / 1 / NM_002731.2 / 84,316,333 / 160,436 / [8]
PRKCA / protein kinase C, alpha / 5578 / 17 / NM_002737.2 / 61,729,388 / 507,936 / [33, 69]
PRKCQ / protein kinase C, theta / 5588 / 10 / NM_006257.2 / 6,509,111 / 153,133 / [80]
PRKDC / protein kinase, DNA-activated, catalytic polypeptide / 5591 / 8 / NM_006904.6 / 48,848,222 / 187,074 / [18, 81, 82]
PTPRC / protein tyrosine phosphatase, receptor type, C / 5788 / 1 / NM_002838.3 / 196,874,760 / 118,408 / [83]
RAF1 / v-raf-1 murine leukemia viral oncogene homolog 1 / 5894 / 3 / NM_002880.2 / 12,600,108 / 80,570 / [8] [84]
RHOA / ras homolog gene family, member A / 387 / 3 / NM_001664.2 / 49,371,582 / 52,948 / [18, 85]
RIPK1 / receptor (TNFRSF)-interacting serine-threonine kinase 1 / 8737 / 6 / NM_003804.3 / 3,022,057 / 38,363 / [14, 44, 86, 87]
RIPK2 / receptor-interacting serine-threonine kinase 2 / 8767 / 8 / NM_003821.5 / 90,839,110 / 33,323 / [88, 89]
RIPK3 / receptor-interacting serine-threonine kinase 3 / 11035 / 14 / NM_006871.3 / 23,875,067 / 4,015 / [90]
SPAG9 / sperm associated antigen 9 / 9043 / 17 / NM_003971.3 / 46,397,987 / 155,107 / [18]
STAT1 / signal transducer and activator of transcription 1, 91kDa / 6772 / 2 / NM_007315.2 / 191,542,121 / 45,060 / [72]
SYK / spleen tyrosine kinase / 6850 / 9 / NM_003177.3 / 92,603,891 / 94,414 / [18, 91]
TBK1 / TANK-binding kinase 1 / 29110 / 12 / NM_013254.2 / 63,132,204 / 49,954 / [92]
TBKBP1 / TBK1 binding protein 1 / 9755 / 17 / NM_014726.1 / 43,127,629 / 16,786 / [93, 94]
TICAM1 / toll-like receptor adaptor molecule 1 / 148022 / 19 / NM_182919.1 / 4,766,992 / 2,459 / [82]
TICAM2 / toll-like receptor adaptor molecule 2 / 353376 / 5 / NM_021649.3 / 114,942,247 / 47,363 / [95]
TIFA / TRAF-interacting protein with forkhead-associated domain / 92610 / 4 / NM_052864.2 / 113,416,231 / 10,277 / [18]
TIRAP / toll-interleukin 1 receptor (TIR) domain containing adaptor protein / 114609 / 11 / NM_001039661.1 / 125,658,192 / 11,846 / [14, 96, 97]
TNF / tumor necrosis factor (TNF superfamily, member 2) / 7124 / 6 / NM_000594.2 / 31,651,329 / 2,762 / [98]
TNFRSF10A / tumor necrosis factor receptor superfamily, member 10a / 8797 / 8 / NM_003844.2 / 23,104,915 / 33,669 / [8, 14, 99]
TNFRSF10B / tumor necrosis factor receptor superfamily, member 10b / 8795 / 8 / NM_003842.3 / 22,933,591 / 49,046 / [100]
TNFRSF10D / tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain / 8793 / 8 / NM_003840.3 / 23,049,046 / 28,439 / [101, 102]
TNFRSF1A / tumor necrosis factor receptor superfamily, member 1A / 7132 / 12 / NM_001065.2 / 6,308,184 / 13,338 / [103]
TNFSF10 / tumor necrosis factor (ligand) superfamily, member 10 / 8743 / 3 / NM_003810.2 / 173,706,158 / 17,805 / [14, 104]
TOLLIP / toll interacting protein / 54472 / 11 / NM_019009.2 / 1,252,177 / 35,238 / [105]
TP53 / tumor protein p53 / 7157 / 17 / NM_000546.3 / 7,512,445 / 19,197 / [106, 107]
TRA@ / T cell receptor alpha locus / 6955 / 14 / 21,159,897 / 931,018 / [108]
TRADD / TNFRSF1A-associated via death domain / 8717 / 16 / NM_003789.3 / 65,745,589 / 5,724 / [109]
TRAF2 / TNF receptor-associated factor 2 / 7186 / 9 / NM_021138.3 / 138,900,786 / 40,102 / [110]
TRAF7 / TNF receptor-associated factor 7 / 84231 / 16 / NM_032271.2 / 2,145,800 / 22,331 / [18]
TRB@ / T cell receptor beta locus / 6957 / 7 / --- / 141,645,314 / 575,783 / [16, 109]
TRD@ / T cell receptor delta locus / 6964 / 14 / --- / 21,961,377 / 44,032 / [111]
TRG@ / T cell receptor gamma locus / 6965 / 7 / --- / 38,246,150 / 128,031 / [112]
TRIP6 / thyroid hormone receptor interactor 6 / 7205 / 7 / NM_003302.2 / 100,302,886 / 6,126 / [113]
VISA / virus-induced signaling adapter / 57506 / 20 / NM_020746.2 / 3,775,484 / 20,489 / [114, 115]
ZAP70 / zeta-chain (TCR) associated protein kinase 70kDa / 7535 / 2 / NM_001079.3 / 97,696,463 / 26,292 / [33]
CFLAR / CASP8 and FADD-like apoptosis regulator / 8837 / 2 / NM_003879.3 / 201,689,135 / 48,125 / [8, 116]
Canonical; Degradation
CSNK2A1 / casein kinase 2, alpha 1 polypeptide / 1457 / 20 / NM_001895.3 / 411,338 / 61,144 / [30, 117]
GSK3A / glycogen synthase kinase 3 alpha / 2931 / 19 / NM_019884.2 / 47,426,178 / 12,398 / [8, 118]
GSK3B / glycogen synthase kinase 3 beta / 2932 / 3 / NM_002093.2 / 121,028,233 / 266,970 / [18]
HNRNPAB / heterogeneous nuclear ribonucleoprotein A/B / 3182 / 5 / NM_004499.3 / 177,564,114 / 6,676 / [14, 119]
RPS6KA1 / ribosomal protein S6 kinase, 90kDa, polypeptide 1 / 6195 / 1 / NM_002953.3 / 26,728,836 / 45,271 / [120]
VCP / valosin-containing protein / 7415 / 9 / NM_007126.2 / 35,046,560 / 16,004 / [14, 121]
Canonical; Inhibition
ARRB1 / arrestin, beta 1 / 408 / 11 / NM_004041.3 / 74,654,130 / 86,391 / [122]
ARRB2 / arrestin, beta 2 / 409 / 17 / NM_004313.3 / 4,560,538 / 11,006 / [123, 124]
ATR / ataxia telangiectasia and Rad3 related / 545 / 3 / NM_001184.3 / 143,650,767 / 129,591 / [8, 9]
BAG4 / BCL2-associated athanogene 4 / 9530 / 8 / NM_004874.2 / 38,153,263 / 34,431 / [87, 125]
BIRC2 / baculoviral IAP repeat-containing 2 / 329 / 11 / NM_001166.3 / 101,723,176 / 31,435 / [107, 126]
CARD6 / caspase recruitment domain family, member 6 / 84674 / 5 / NM_032587.3 / 40,877,167 / 14,046 / [15]
CARD8 / caspase recruitment domain family, member 8 / 22900 / 19 / NM_014959.1 / 53,403,325 / 41,412 / [15]
CDKN2A / cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) / 1029 / 9 / NM_058195.2 / 21,957,751 / 26,739 / [8, 116]
CHEK1 / CHK1 checkpoint homolog (S. pombe) / 1111 / 11 / NM_001274.3 / 125,001,547 / 29,300 / [127]
CLU / clusterin / 1191 / 8 / NM_001831.2 / 27,510,368 / 17,876 / [26, 128]
CYLD / cylindromatosis (turban tumor syndrome) / 1540 / 16 / NM_015247.2 / 49,333,462 / 59,885 / [129]
EGR1 / early growth response 1 / 1958 / 5 / NM_001964.2 / 137,829,080 / 3,823 / [71, 72]
ESR1 / estrogen receptor 1 / 2099 / 6 / NM_000125.2 / 152,170,379 / 295,720 / [33]
ESR2 / estrogen receptor 2 (ER beta) / 2100 / 14 / NM_001040276.1 / 63,763,504 / 111,517 / [33]
G3BP2 / GTPase activating protein (SH3 domain) binding protein 2 / 9908 / 4 / NM_203504.1 / 76,786,990 / 30,639 / [18, 130, 131]
HEXIM1 / hexamethylene bis-acetamide inducible 1 / 10614 / 17 / NM_006460.2 / 40,580,467 / 4,784 / [28]
HMOX1 / heme oxygenase (decycling) 1 / 3162 / 22 / NM_002133.1 / 34,107,087 / 13,107 / [14, 93]
IL10 / interleukin 10 / 3586 / 1 / NM_000572.2 / 205,007,571 / 4,891 / [40]
IL1RN / interleukin 1 receptor antagonist / 3557 / 2 / NM_000577.3 / 113,591,941 / 16,123 / [18]
IL3 / interleukin 3 (colony-stimulating factor, multiple) / 3562 / 5 / NM_000588.3 / 131,424,246 / 2,549 / [18]
IRAK3 / interleukin-1 receptor-associated kinase 3 / 11213 / 12 / NM_007199.1 / 64,869,284 / 59,368 / [73]
ITGA3 / integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) / 3675 / 17 / NM_002204.1 / 45,488,730 / 34,113 / [4]
MCC / mutated in colorectal cancers / 4163 / 5 / NM_001085377.1 / 112,385,695 / 466,731 / [132]
MDM2 / Mdm2 p53 binding protein homolog (mouse) / 4193 / 12 / NM_002392.2 / 67,488,247 / 32,234 / [133]
NFKBIA / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha / 4792 / 14 / NM_020529.1 / 34,940,468 / 3,227 / [18, 82]
NFKBIB / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta / 4793 / 19 / NM_002503.3 / 44,082,455 / 8,919 / [134]
NFKBIE / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon / 4794 / 6 / NM_004556.2 / 44,333,881 / 7,622 / [135]
NFKBIZ / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta / 64332 / 3 / NM_001005474.1 / 103,029,547 / 33,009 / [136]
NKIRAS1 / NFKB inhibitor interacting Ras-like 1 / 28512 / 3 / NM_020345.3 / 23,908,576 / 24,965 / [71, 72]
NKIRAS2 / NFKB inhibitor interacting Ras-like 2 / 28511 / 17 / NM_001001349.1 / 37,422,564 / 8,621 / [33, 69]
NLRP12 / NLR family, pyrin domain containing 12 / 91662 / 19 / NM_144687.1 / 58,988,650 / 30,754 / [33, 69]
NR1D1 / nuclear receptor subfamily 1, group D, member 1 / 9572 / 17 / NM_021724.2 / 35,502,567 / 7,932 / [33, 69]
OTUD7B / OTU domain containing 7B / 56957 / 1 / NM_020205.2 / 148,178,855 / 70,455 / [33, 69]
PGR / progesterone receptor / 5241 / 11 / NM_000926.3 / 100,414,313 / 92,152 / Extension to tcrs from [73]
PKN1 / protein kinase N1 / 5585 / 19 / NM_002741.3 / 14,405,166 / 38,513 / [77]
PPARA / peroxisome proliferator-activated receptor alpha / 5465 / 22 / NM_005036.4 / 44,925,163 / 93,154 / [82]
PPARG / peroxisome proliferator-activated receptor gamma / 5468 / 3 / NM_005037.5 / 12,304,349 / 146,506 / [14, 137]
PPP1R13L / protein phosphatase 1, regulatory (inhibitor) subunit 13 like / 10848 / 19 / NM_006663.2 / 50,574,736 / 25,393 / [14, 137]
PPP6C / protein phosphatase 6, catalytic subunit / 5537 / 9 / NM_002721.3 / 126,951,228 / 40,658 / [8]
PTPN13 / protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) / 5783 / 4 / NM_006264.1 / 87,734,909 / 220,417 / [44, 138]
PYCARD / PYD and CARD domain containing / 29108 / 16 / NM_013258.3 / 31,120,308 / 1,444 / [89, 139]
RNF216 / ring finger protein 216 / 54476 / 7 / NM_207111.2 / 5,626,204 / 161,614 / [140]
SOD1 / superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) / 6647 / 21 / NM_000454.4 / 31,953,806 / 9,309 / [72]
TAL1 / T-cell acute lymphocytic leukemia 1 / 6886 / 1 / NM_003189.1 / 47,454,551 / 13,479 / [18]
TNFAIP3 / tumor necrosis factor, alpha-induced protein 3 / 7128 / 6 / NM_006290.2 / 138,230,274 / 15,868 / [141, 142]
TNIP1 / TNFAIP3 interacting protein 1 / 10318 / 5 / NM_006058.3 / 150,389,699 / 51,491 / [143]
TNIP2 / TNFAIP3 interacting protein 2 / 79155 / 4 / NM_024309.2 / 2,713,185 / 14,674 / [144] [111, 145]
TNIP3 / TNFAIP3 interacting protein 3 / 79931 / 4 / NM_024873.3 / 122,272,017 / 32,909 / [146, 147]
TRAF1 / TNF receptor-associated factor 1 / 7185 / 9 / NM_005658.3 / 122,704,493 / 24,501 / [18, 148]
TRIB3 / tribbles homolog 3 (Drosophila) / 57761 / 20 / NM_021158.3 / 309,308 / 16,895 / [149]
Canonical; Nuclear Function
BCL3 / B-cell CLL/lymphoma 3 / 602 / 19 / NM_005178.3 / 49,943,820 / 11,321 / [11]
DHX9 / DEAH (Asp-Glu-Ala-His) box polypeptide 9 / 1660 / 1 / NM_001357.3 / 181,075,074 / 48,433 / [72, 105]
F2R / coagulation factor II (thrombin) receptor / 2149 / 5 / NM_001992.2 / 76,047,542 / 19,512 / [33]
KPNA3 / karyopherin alpha 3 (importin alpha 4) / 3839 / 13 / NM_002267.2 / 49,171,462 / 93,596 / [150]
NCOA3 / nuclear receptor coactivator 3 / 8202 / 20 / NM_006534.2 / 45,564,064 / 154,959 / [151, 152]
NKAP / NFKB activating protein / 79576 / X / NM_024528.1 / 118,943,051 / 18,712 / [33, 69]
PRKCZ / protein kinase C, zeta / 5590 / 1 / NM_002744.4 / 1,971,769 / 134,925 / [18, 153]
RNF25 / ring finger protein 25 / 64320 / 2 / NM_022453.2 / 219,236,831 / 8,194 / [140]
RPS6KA4 / ribosomal protein S6 kinase, 90kDa, polypeptide 4 / 8986 / 11 / NM_003942.2 / 63,883,201 / 13,062 / [72]
RPS6KA5 / ribosomal protein S6 kinase, 90kDa, polypeptide 5 / 9252 / 14 / NM_004755.2 / 90,406,912 / 189,834 / [16]
STAT3 / signal transducer and activator of transcription 3 (acute-phase response factor) / 6774 / 17 / NM_003150.3 / 37,718,869 / 75,170 / [44, 154]
Canonical; Subunits
NFKB1 / nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) / 4790 / 4 / NM_003998.2 / 103,641,518 / 115,989 / [72]
REL / v-rel reticuloendotheliosis viral oncogene homolog (avian) / 5966 / 2 / NM_002908.2 / 60,962,256 / 41,426 / [43, 155]
RELA / v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) / 5970 / 11 / NM_021975.2 / 65,178,393 / 8,558 / [156]
Canonical & Non-Canonical; Activation
CHUK / conserved helix-loop-helix ubiquitous kinase / 1147 / 10 / NM_001278.3 / 101,938,114 / 41,220 / [157]
FKBP5 / FK506 binding protein 5 / 2289 / 6 / NM_004117.2 / 35,649,345 / 115,347 / [158]
IKBKAP / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein / 8518 / 9 / NM_003640.2 / 110,669,621 / 66,596 / [8, 159]
NIBP / trafficking protein particle complex 9 / 83696 / 8 / NM_031466.4 / 140,811,770 / 726,090 / [33, 69]
TANK / TRAF family member-associated NFKB activator / 10010 / 2 / NM_004180.2 / 161,701,712 / 99,216 / [14, 96, 97]
TLR1 / toll-like receptor 1 / 7096 / 4 / NM_003263.3 / 38,474,271 / 8,536 / [79]
TLR10 / toll-like receptor 10 / 81793 / 4 / NM_030956.2 / 38,450,629 / 10,355 / [8, 160]
TLR2 / toll-like receptor 2 / 7097 / 4 / NM_003264.3 / 154,824,891 / 21,802 / [160]
TLR3 / toll-like receptor 3 / 7098 / 4 / NM_003265.2 / 187,227,303 / 15,943 / [161]
TLR4 / toll-like receptor 4 / 7099 / 9 / NM_138554.2 / 119,506,431 / 13,158 / [108, 162, 163]
TLR5 / toll-like receptor 5 / 7100 / 1 / NM_003268.4 / 221,350,207 / 33,040 / [164]
TLR6 / toll-like receptor 6 / 10333 / 4 / NM_006068.2 / 38,504,803 / 2,752 / [14, 165]
TLR7 / toll-like receptor 7 / 51284 / X / NM_016562.3 / 12,795,123 / 23,278 / [142, 166]
TLR8 / toll-like receptor 8 / 51311 / X / NM_138636.3 / 12,834,679 / 16,530 / [167]
TLR9 / toll-like receptor 9 / 54106 / 3 / NM_017442.2 / 52,230,138 / 5,081 / [142]
TNFRSF1B / tumor necrosis factor receptor superfamily, member 1B / 7133 / 1 / NM_001066.2 / 12,149,647 / 42,217 / [168]
TRAF5 / TNF receptor-associated factor 5 / 7188 / 1 / NM_004619.3 / 209,566,580 / 48,331 / [169]
TRAF6 / TNF receptor-associated factor 6 / 7189 / 11 / NM_004620.2 / 36,467,302 / 21,096 / [33, 69]
XIAP / X-linked inhibitor of apoptosis / 331 / X / NM_001167.2 / 122,821,729 / 53,774 / [8]
Canonical & Non-Canonical; Degradation
BTRC / beta-transducin repeat containing / 8945 / 10 / NM_003939.3 / 103,103,815 / 203,245 / [161]
CAPN1 / calpain 1, (mu/I) large subunit / 823 / 11 / NM_005186.2 / 64,705,919 / 30,133 / [170]
CUL1 / cullin 1 / 8454 / 7 / NM_003592.2 / 148,026,866 / 102,269 / [18, 171]
FBXW11 / F-box and WD repeat domain containing 11 / 23291 / 5 / NM_012300.2 / 171,221,161 / 145,321 / [33]
FBXW7 / F-box and WD repeat domain containing 7 / 55294 / 4 / NM_033632.2 / 153,461,860 / 213,762 / [8, 172]
RBX1 / ring-box 1 / 9978 / 22 / NM_014248.2 / 39,677,331 / 21,283 / [14, 18, 87]
SKP1 / S-phase kinase-associated protein 1 / 6500 / 5 / NM_006930.2 / 133,520,468 / 20,115 / [18, 20, 133]
SUMO4 / SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) / 387082 / 6 / NM_001002255.1 / 149,763,188 / 687 / [173]
UBE2D1 / ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) / 7321 / 10 / NM_003338.3 / 59,764,745 / 35,770 / [15]
UBE2D2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / 7322 / 5 / NM_003339.2 / 138,920,935 / 67,268 / [33, 69]
UBE2N / ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) / 7334 / 12 / NM_003348.3 / 92,326,219 / 33,938 / [76, 115]
UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1 / 7335 / 20 / NM_021988.4 / 48,131,068 / 34,833 / [174]
USP11 / ubiquitin specific peptidase 11 / 8237 / X / NM_004651.3 / 46,977,258 / 15,413 / [175]
Canonical & Non-Canonical; Inhibition
TTRAP / TRAF and TNF receptor associated protein / 51567 / 6 / NM_016614.2 / 24,758,184 / 16,910 / [76]
Canonical & Non-Canonical; Nuclear Function
FUS / fusion (involved in t(12;16) in malignant liposarcoma) / 2521 / 16 / NM_004960.2 / 31,098,954 / 11,647 / [176]
RPS6KA3 / ribosomal protein S6 kinase, 90kDa, polypeptide 3 / 6197 / X / NM_004586.2 / 20,077,950 / 116,721 / [8] [172]
ATF1 / activating transcription factor 1 / 466 / 12 / NM_005171.3 / 49,444,086 / 57,088 / [8]
CREB1 / cAMP responsive element binding protein 1 / 1385 / 2 / NM_004379.2 / 208,102,931 / 68,887 / [177]
CREBBP / CREB binding protein (Rubinstein-Taybi syndrome) / 1387 / 16 / NM_004380.2 / 3,715,056 / 155,066 / [71, 72]
EP300 / E1A binding protein p300 / 2033 / 22 / NM_001429.2 / 39,818,553 / 87,471 / [33]
GTF2A1 / general transcription factor IIA, 1, 19/37kDa / 2957 / 14 / NM_201595.1 / 80,716,147 / 41,181 / [178]
GTF2A2 / general transcription factor IIA, 2, 12kDa / 2958 / 15 / NM_004492.1 / 57,718,358 / 18,629 / [18, 44]
GTF2B / general transcription factor IIB / 2959 / 1 / NM_001514.4 / 89,090,909 / 38,980 / [67]
GTF2E1 / general transcription factor IIE, polypeptide 1, alpha 56kDa / 2960 / 3 / NM_005513.2 / 121,944,248 / 40,358 / [179]
GTF2E2 / general transcription factor IIE, polypeptide 2, beta 34kDa / 2961 / 8 / NM_002095.4 / 30,555,573 / 79,707 / [180]
GTF2F1 / general transcription factor IIF, polypeptide 1, 74kDa / 2962 / 19 / NM_002096.2 / 6,330,580 / 13,711 / [8]
GTF2F2 / general transcription factor IIF, polypeptide 2, 30kDa / 2963 / 13 / NM_004128.1 / 44,592,672 / 163,565 / [181]
GTF2H1 / general transcription factor IIH, polypeptide 1, 62kDa / 2965 / 11 / NM_005316.2 / 18,300,719 / 44,434 / [182]
GTF2H2 / general transcription factor IIH, polypeptide 2, 44kDa / 2966 / 5 / NM_001515.3 / 70,366,707 / 32,546 / [8]
GTF2H3 / general transcription factor IIH, polypeptide 3, 34kDa / 2967 / 12 / NM_001516.3 / 122,684,334 / 26,953 / [183]
GTF2H4 / general transcription factor IIH, polypeptide 4, 52kDa / 2968 / 6 / NM_001517.4 / 30,983,956 / 5,903 / [184]
GTF2H5 / general transcription factor IIH, polypeptide 5 / 404672 / 6 / NM_207118.1 / 158,511,489 / 21,886 / [185]
HDAC1 / histone deacetylase 1 / 3065 / 1 / NM_004964.2 / 32,530,295 / 41,516 / [186]
HDAC3 / histone deacetylase 3 / 8841 / 5 / NM_003883.3 / 140,980,627 / 15,980 / [187]
HDAC6 / histone deacetylase 6 / 10013 / X / NM_006044.2 / 48,545,431 / 22,893 / [188]
JUN / jun oncogene / 3725 / 1 / NM_002228.3 / 59,019,051 / 3,322 / [4]
MAPK1 / mitogen-activated protein kinase 1 / 5594 / 22 / NM_002745.4 / 20,443,946 / 108,024 / [189]
MAPK3 / mitogen-activated protein kinase 3 / 5595 / 16 / NM_002746.2 / 30,032,927 / 9,204 / [190]
MCM5 / minichromosome maintenance complex component 5 / 4174 / 22 / NM_006739.3 / 34,126,116 / 24,379 / [8]
MCM7 / minichromosome maintenance complex component 7 / 4176 / 7 / NM_005916.3 / 99,528,340 / 9,023 / [79]
PCAF / p300/CBP-associated factor / 8850 / 3 / NM_003884.4 / 20,056,528 / 114,372 / [191, 192]
POLR2A / polymerase (RNA) II (DNA directed) polypeptide A, 220kDa / 5430 / 17 / NM_000937.2 / 7,328,422 / 30,231 / [193]
POLR2B / polymerase (RNA) II (DNA directed) polypeptide B, 140kDa / 5431 / 4 / NM_000938.1 / 57,539,866 / 52,225 / [127, 194]
POLR2C / polymerase (RNA) II (DNA directed) polypeptide C, 33kDa / 5432 / 16 / NM_032940.2 / 56,054,052 / 9,370 / [14, 18]
POLR2D / polymerase (RNA) II (DNA directed) polypeptide D / 5433 / 2 / NM_004805.2 / 128,320,703 / 11,471 / [14, 18, 19]
POLR2E / polymerase (RNA) II (DNA directed) polypeptide E, 25kDa / 5434 / 19 / NM_002695.2 / 1,039,163 / 7,173 / [22, 151]
POLR2F / polymerase (RNA) II (DNA directed) polypeptide F / 5435 / 22 / NM_021974.2 / 36,679,664 / 14,088 / [18, 195]
POLR2G / polymerase (RNA) II (DNA directed) polypeptide G / 5436 / 11 / NM_002696.1 / 62,285,591 / 5,166 / [20, 196]
POLR2H / polymerase (RNA) II (DNA directed) polypeptide H / 5437 / 3 / NM_006232.2 / 185,563,888 / 5,169 / [95, 197]
POLR2I / polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa / 5438 / 19 / NM_006233.4 / 41,296,451 / 1,595 / [14, 95]
POLR2J / polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa / 5439 / 7 / NM_006234.4 / 101,900,552 / 5,834 / [67]
POLR2K / polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa / 5440 / 8 / NM_005034.3 / 101,232,015 / 3,391 / [198]
POLR2L / polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa / 5441 / 11 / NM_021128.3 / 829,721 / 2,808 / [82]
SP1 / Sp1 transcription factor / 6667 / 12 / NM_138473.2 / 52,060,246 / 36,251 / [199]
TAF1 / TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa / 6872 / X / NM_004606.2 / 70,502,839 / 98,186 / [18]
TAF10 / TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa / 6881 / 11 / NM_006284.2 / 6,588,649 / 1,372 / [8, 200]
TAF11 / TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa / 6882 / 6 / NM_005643.2 / 34,953,533 / 10,264 / [82]
TAF12 / TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa / 6883 / 1 / NM_005644.2 / 28,802,200 / 39,972 / [162]
TAF13 / TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa / 6884 / 1 / NM_005645.3 / 109,408,521 / 11,626 / [18]
TAF15 / TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa / 8148 / 17 / NM_003487.2 / 31,160,601 / 37,750 / [18, 148]
TAF2 / TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa / 6873 / 8 / NM_003184.3 / 120,812,195 / 102,060 / [201]
TAF3 / TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa / 83860 / 10 / NM_031923.2 / 7,900,679 / 196,041 / [111]
TAF4 / TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa / 6874 / 20 / NM_003185.3 / 59,983,249 / 91,012 / [14, 202, 203]
TAF4B / TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa / 6875 / 18 / NM_005640.1 / 22,060,407 / 165,240 / [204]
TAF5 / TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa / 6877 / 10 / NM_006951.3 / 105,117,714 / 21,098 / [41, 205]
TAF6 / TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa / 6878 / 7 / NM_139315.1 / 99,542,629 / 12,286 / [206]
TAF7 / TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa / 6879 / 5 / NM_005642.2 / 140,678,241 / 2,294 / [207]
TAF8 / TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa / 129685 / 6 / NM_138572.2 / 42,126,229 / 30,393 / [123, 208]
TAF9 / TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa / 6880 / 5 / NM_001015891.1 / 68,683,309 / 18,287 / [156]
TBP / TATA box binding protein / 6908 / 6 / NM_003194.3 / 170,705,396 / 18,476 / [209]
Non-Canonical; Activation
CD40 / CD40 molecule, TNF receptor superfamily member 5 / 958 / 20 / NM_001250.4 / 44,180,313 / 11,478 / [71, 72]
CD40LG / CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) / 959 / X / NM_000074.2 / 135,558,002 / 12,213 / [8, 210]
DYNLL1 / dynein, light chain, LC8-type 1 / 8655 / 12 / NM_001037494.1 / 119,392,043 / 28,638 / [211]
LTA / lymphotoxin alpha (TNF superfamily, member 1) / 4049 / 6 / NM_000595.2 / 31,648,072 / 2,005 / [53]
LTB / lymphotoxin beta (TNF superfamily, member 3) / 4050 / 6 / NM_002341.1 / 31,656,314 / 1,867 / [53]
LTBR / lymphotoxin beta receptor (TNFR superfamily, member 3) / 4055 / 12 / NM_002342.1 / 6,363,618 / 7,375 / [18, 53]
MAP3K14 / mitogen-activated protein kinase kinase kinase 14 / 9020 / 17 / NM_003954.2 / 40,696,271 / 53,926 / [195]
TNFRSF11A / tumor necrosis factor receptor superfamily, member 11a, NFKB activator / 8792 / 18 / NM_003839.2 / 58,143,528 / 60,956 / [18]
TNFRSF13B / tumor necrosis factor receptor superfamily, member 13B / 23495 / 17 / NM_012452.2 / 16,783,123 / 33,004 / [212]
TNFRSF13C / tumor necrosis factor receptor superfamily, member 13C / 115650 / 22 / NM_052945.2 / 40,650,982 / 1,746 / [213, 214]
TNFSF11 / tumor necrosis factor (ligand) superfamily, member 11 / 8600 / 13 / NM_033012.2 / 42,043,795 / 36,353 / [215]
Non-Canonical; Inhibition
IFNG / interferon, gamma / 3458 / 12 / NM_000619.2 / 66,834,817 / 4,971 / [176]
TRAF3 / TNF receptor-associated factor 3 / 7187 / 14 / NM_003300.2 / 102,313,569 / 128,812 / [148]
TRAF3IP2 / TRAF3 interacting protein 2 / 10758 / 6 / NM_147686.1 / 111,986,836 / 47,178 / [216]
Non-Canonical; Nuclear Function
KPNA2 / karyopherin alpha 2 (RAG cohort 1, importin alpha 1) / 3838 / 17 / NM_002266.2 / 63,462,310 / 11,122 / [4]
KPNA6 / karyopherin alpha 6 (importin alpha 7) / 23633 / 1 / NM_012316.4 / 32,346,231 / 68,525 / [38]
Non-Canonical; Subunits
NFKB2 / nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) / 4791 / 10 / NM_001077493.1 / 104,144,219 / 8,052 / [61]
RELB / v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian) / 5971 / 19 / NM_006509.2 / 50,196,552 / 36,740 / [140]
Unknown; Inhibition
NKRF / NFKB repressing factor / 55922 / X / NM_017544.2 / 118,606,334 / 17,507 / [33, 69]
Unknown; Unknown
NFKBIL1 / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 / 4795 / 6 / NM_005007.2 / 31,623,351 / 11,234 / [217]
NFKBIL2 / nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 / 4796 / 8 / NM_013432.3 / 145,624,984 / 15,605 / [67]
NFRKB / nuclear factor related to kappaB binding protein / 4798 / 11 / NM_006165.2 / 129,239,568 / 28,546 / [33, 69]
TCEAL7 / transcription elongation factor A (SII)-like 7 / 56849 / X / NM_152278.2 / 102,471,821 / 2,089 / [14, 191]
Genes are list under classifications by sub-pathway and biological function; position based on genome build 36.3 gene start;TRA@, TRB@, TRD@, and TRG@ are gene loci that have no RefSeq IDs; HSP90AA2 is a pseudo-gene and has no RefSeq ID.
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