Supplemental Table 1: Demographic variables (age, education level), pain and experimental threshold, and clinical characteristics (trait dissociation, symptom severity, co-occurring psychiatric disorders) of the full sample of patients with Borderline Personality Disorder (BPD) and healthy controls (HC)
BPD [Mean (SD)]n = 34 / HC [Mean (SD)]
n= 32 / Statistics
(t-Test, Chi²-test)
Age / 27.6 (7.5) / 27.8 (7.5) / t= .098, df=63, p=.922
Educationlevel:
University
College
Apprenticeship
No higher education / 2
3
15
13 / 8
5
10
6 / Chi2=7.45, p=.059
Pain Threshold / 3.52 (2.26) / 2.49 (1.49) / t=2.09, df=50, p=.042
Threshold experiment / 4.47 (2.55) / 2.98 (1.62) / t=2.71, df=49, p=.009
Trait Dissociation (FDS) / 26.10 (14.17) / 3.26 (5.92) / t=8.13, df=57, p<.001
Symptom Severity (BSL) / 1.83 (0.66) / 0.34 (0.19) / t=12.37, df=38, p<.001
Major Depression current/lifetime / 0/26 / 0/0 / -
Anxiety Disorders current/lifetime / 24/25 / 0/0 / -
PTSD current/lifetime / 14/18 / 0/0 / -
Eating Disorder current/litetime / 6/16 / 0/0 / -
Note: n= sample size, SD = standarddeviation, FDS= ‘Fragebogen zu Dissoziativen Symptomen‘ (German version of theDissociative Experience Scale); BSL=Borderline Symptom List; PTSD=Posttraumatic Stress Disorder
Supplemental Table 2: Demographic variables (age, education level),pain and experimental threshold, trait dissociation, and symptom severity of Borderline Personality Disorder (BPD) patients and healthy controls (HC) included in the analysis of skin conductance response(Conditioning Session 1: BPD n=21, HC n=21; Session 2 (Extinction recall, Reacquisition): BPD n=14, HC n=15 ))
BPD [Mean (SD)] / HC [Mean (SD)] / Statistics(t-Test, Chi²-test)
Age
Conditioning Session 1
Conditioning Session 2 / 26.73 (7.74)
28.07 (6.18) / 29.55 (8.54)
29.45 (7.95) / t=1.12, df=40, p=.268
t=0.49, df=23, p=.629
Education level
Conditioning Session 1:
University
College
Apprenticeship
No higher education
Education level
Conditioning Session 2:
University
College
Apprenticeship
No higher education / 1
2
12
7
0
4
5
5 / 5
4
6
4
4
3
3
1 / Chi2=5.96, df=3, p=.113
Chi2=7.05,df=3, p=.070
Pain Threshold
Conditioning Session 1
Conditioning Session 2 / 3.50 (2.39)
2.73 (1.68) / 2.27 (1.00)
2.30 (1.28) / t=2.08, df=36, p=.049
t=0.70.;df=22, p=.493
Threshold experiment
Conditioning Session 1
Conditioning Session 2 / 4.39 (2.67)
3.65 (2.28) / 2.77 (1.41)
2.95 (1.66) / t=2.34, df=36, p=.027.
t=0.85, df=22, p=.407
Trait Dissociation (FDS)
Conditioning Session 1
Conditioning Session 2 / 23.98 (15.49)
30.39 (18.20) / 1.81 (1.24)
1.66 (1.16) / t=6.05, df=34, p<.001
t=5.23,df=20, p<.001
Symptom Severity (BSL)
Conditioning Session 1
Conditioning Session 2 / 1.73 (0.73)
2.02 (0.76) / 0.29 (0.08)
0.27 (0.08) / t=8.29, df=37, p<.001
t=7.59, df=22, p<.001
Note: n=sample size, SD=standard deviation, FDS=‘Fragebogen zu Dissoziativen Symptomen‘ (German version of the Dissociative Experience Scale); BSL=Borderline Symptom List; PTSD=Posttraumatic Stress Disorder
Supplemental Table 3: Demographic variables, pain and experimental threshold,trait dissociation, and symptom severity of Borderline Personality Disorder (BPD) patients and healthy controls (HC) included in the neuroimaging analysis (Conditioning Session 1: BPD n=27, HC n=26; Extinction recall: BPD n=21, HC n=22; Reacquisition: BPD n=24, HC n=17)
BPD [Mean (SD)] / HC [Mean (SD)] / Statistics(t-Test, Chi²-test)
Age
Conditioning Session 1:
Extinction recall:
Re-acquisition: / 27.59 (6.50)
26.29 (6.47)
26.38 (6.50) / 28.16 (8.26)
27.95 (8.13)
26.81 (6.12) / t=.28,df=50, p=.783
t=0.74, df=40, p=.467
t=0.21, df=38, p=.837
Education level
ConditioningSession 1:
University
College
Apprenticeship
No higher education
Extinctionrecall:
University
College
Apprenticeship
No higher education
Re-acquisition:
University
College
Apprenticeship
No higher education / 2
2
13
9
1
2
9
8
1
3
10
9 / 7
4
7
5
4
4
8
4
3
3
5
4 / Chi2=6.23, df=3, p=.101
Chi2=3.86,df=3, p=.277
Chi2=3.04, df=3, p=.385
Pain Threshold
ConditioningSession 1:
Extinction recall:
Re-acquisition: / 3.45 (2.31)
3.68 (2.40)
3.58 (2.38) / 2.33 (1.13)
2.45 (1.59)
2.57 (1.72) / t=2.10, df=45, p=.044.
t=1.93, df=40, p=.062
t=1.51, df=36; p=.140
Threshold experiment
ConditioningSession 1:
Extinction recall:
Re-acquisition: / 4.46 (2.57)
4.59 (2.71)
4.45 (2.71) / 2.84 (1.43)
2.85 (1.56)
3.09 (1.64) / t=2.65, df=45; p=.012
t=2.51, df=40, p=.018
t=1.96, df=36; p=.059
Trait Dissociation (FDS)
ConditioningSession 1:
Extinction recall:
Re-acquisition: / 28.53 (14.77)
24.58 (16.10)
24.50 (14.86) / 2.18 (1.38)
3.69 (6.87)
3.88 (7.80) / t=8.34, df=44, p<.0001
t=5.14, df=38, p<.0001
t=5.49, df=36; p<.0001
Symptom Severity (BSL)
ConditioningSession 1:
Extinction recall:
Re-acquisition: / 1.93 (0.66)
1.83 (0.70)
1.82 (0.65) / 0.33 (0.13)
0.34 (0.19)
0.35 (0.22) / t=12.08, df=44, p<.0001
t=9.48, df=41, p<.0001
t=10.27, df=39, p<.0001
Note: n=sample size, SD=standarddeviation,FDS=‘Fragebogen zu Dissoziativen Symptomen‘ (German version of theDissociative Experience Scale); BSL=Borderline Symptom List; PTSD=Posttraumatic Stress Disorder