Supplemental Table 1. Associations Between Tlr2snpsand Asthma Outcomes in the First 8 Years

Supplemental Table 1. Associations between TLR2SNPsand asthma outcomes in the first 8 years of life adjusted for confounders.

TLR2 SNP / Doctor diagnosed asthma
OR (95% CI) / Asthma symptoms
OR (95% CI)
Rs4696480 / TA vs TT
0.61 (0.38-0.98) / AA vs TT
0.53 (0.30-0.95) / TA vs TT
0.83 (0.61-1.12) / AA vs TT
0.82 (0.57-1.19)
Rs1898830 / AG vs AA
1.35 (0.84-2.17) / GG vs AA
1.65 (0.87-3.13) / AG vs AA
1.11 (0.83-1.49) / GG vs AA
1.22 (0.81-1.84)
Rs3804099 / TC vs TT
0.84 (0.52-1.37) / CC vs TT
0.93 (0.49-1.74) / TC vs TT
0.95 (0.70-1.28) / CC vs TT
1.02 (0.69-1.51)
Rs3804100 / TC or CC vs TT
0.96 (0.52-1.78) / TC or CC vs TT
1.05 (0.71-1.54)

Bold indicates p<0.05.

Supplemental Table 2. Associations between TLR4SNPs and asthma outcomes in the first 8 years of life adjusted for confounders.

TLR4 SNP / Doctor diagnosed asthma
OR (95% CI) / Asthma symptoms
OR (95% CI)
Rs2770150 / TC vs TT
0.88 (0.56-1.36) / CC vs TT
0.71 (0.29-1.74) / TC vs TT
1.00 (0.77-1.31) / CC vs TT
0.81 (0.48-1.37)
Rs10759931 / GA vs GG
1.18 (0.75-1.87) / AA vs GG
1.07 (0.57-2.01) / GA vs GG
1.04 (0.77-1.40) / AA vs GG
1.12 (0.78-1.62)
Rs6478317 / AG vs AA
1.03 (0.68-1.55) / GG vs AA
0.89 (0.45-1.76) / AG vs AA
1.16 (0.88-1.52) / GG vs AA
0.83 (0.53-1.30)
Rs10759932 / CT or CC vs TT
0.81 (0.49-1.31) / CT or CC vs TT
0.83 (0.60-1.14)
Rs1927911 / CT vs CC
1.29 (0.86-1.92) / TT vs CC
0.94 (0.40-2.20) / CT vs CC
0.96 (0.72-1.27) / TT vs CC
1.18 (0.71-1.96)
Rs11536878 / CA or AA vs CC
0.65 (0.40-1.03) / CA or AA vs CC
0.88 (0.63-1.21)
Rs4986790 / AG or GG vs AA
1.58 (0.76-3.29) / AG or GG vs AA
1.02 (0.66-1.56)
Rs4986791 / CT or TT vs CC
1.69 (0.76-3.75) / CT or TT vs CC
1.05 (0.67-1.64)
Rs11536889 / GC or CC vs GG
0.86 (0.56-1.33) / GC or CC vs GG
0.87 (0.65-1.15)