STUDY ON THE CHEMICAL CONSTITUENTS IN LANTANA CAMARA L. LEAVES

ARPANA MISHRA AND RAVINDRA SINGH

Department of Botany,

M.G.C.G.V. Chitrakoot,

SATNA (M.P.),INDIA

ABSTRACT

Lantana camara has allelopathic properties which effect in the germination and growth of surrounding plants. Allelopathic effect shows due to the presence of some allelochemicals which are present in plant leaf at about 78 chemical constituents are identified during the study . The following allelochemicals triterpenoids betulonic acid lantadene A , lantadene B, lantadene C, camaraside, flavonoids ,ursolic acid , palmitic acid, oleanolic acid were isolated from the leaves of the yellow pink Lantana camara L.

Table :01 Figure :00 References : 07
KEY WORDS : Allelochemical, Lantana camara, Triterpenoid

Introduction

Lantana camara is a notorious weed belonging to verbenaceae family. It is native to tropical and subtropical America and popular ornamental garden plant. Lantana camara grows under varying conditions of climate and soil and commonly known ach man, big sage, lantana, flowered sage. Allelochemicals are present in leaves, stem, roots and flowers of Lantana but leaves are the major source of allelochemicals. Lantadene A and lantadene B as more potent allelochemicals. First systematic study on the chemical constituents of Lantana camara was undertaken in 1943 by P.G.J. Louw.

Extract from the leaves have been reported to have antimicrobial, fungicidal, insecticidal and nematicidal activity ( Saksena et al., 1985 ; Begun et al., 1995; Sharma et al., 1999; Deena et al., 2000). Lantana camara leaf allelochemicals can use growth control allergic plant Parthenium hysterophorus ( Ravindra et al., 2008 ).

The present paper deals with the identification of allelochemicals present in leaf of Lantana camara . Identified allelochemicals are useful in medicine.

Materials and Method

Lantana camara leaves ( yellow pink flower ) were collected from Chitrakoot . The air dried leaves ( 10 Kg ) of L. camara were extracted with MeOH under reflux. This extract showed inhibitory effect and classical methods of separation followed by vacuum liquid chromatography, flash column chromatography, column chromatography and preparative thin layer chromatography as used in the experiment.

The chemical characterization of Lantana camara leaf were analyze according to the Aneela wahab 2004.

Result and Disscution

The constituents isolated from Lantana camara leaves are listed in Table 1.

Table-1 Chemical constituents of Lantana camara leaf.

S.NO / Name / Molecular formula
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20 / α-Amyrin
22 β-Angeloyloxy-
3 β–hydroxyolean-
12-en-28-oic acid
(reduced lantadene A)
Arachidic acid
Betulic acid
Betulonic acid
Cadinene
α-Cadinol
Calceolarioside E
Camaraside
Camaric acid
Camarinic acid
Camaroside
Campesterol acetate
Cedrene
1,8-Cineole
Citral
ρ-Coumarie acid
ρ-Cymene
Derhamnosyl
verbascoside
3,7-Dimethoxy
quercetin / C30H50O
C35H54O5
C20H40O2
C30H43O3
C30H46O3
C15H24
C15H26O
C28H34O15
C23H24O12
C35H52O6
C32H48O6
C23H24O11
C30H50O2
C15H24
C10H18O
C10H16O
C9H8O3
C10H14
C23H26O11
C17H14O7
21
22
23
24
25
26
27
28
28
29
30
31
32
33
34
35
36
37
/ 22 β-Dimethyl- acryloxy-3β- hydroxyolean-12-
en-28-oic acid
(reduced lantadene B)
22 β–Dimethylacry-
loyloxylantanolic acid
22 β-Dimethyl-
acryloyloxylantic acid
Dipentene
Eugenol
Farnesol
Furfural
Geraniol
Glucose
Hispidulin
ρ-Hydroxybenzoic acid
22 β– Hydroxy-3- oxoolean-12-en-28-oic acid
Icterogenin
Isonuomioside A
Isoverbascoside
Lancamarone
Lantabetulic acid
Lantadene A / C35H54O5
C35H52O6
C35H52O6
C10H16
C10H12O2
C15H26O
C5H4O2
C10H18O
C6H12O6
C16H12O6
C7H6O3
C30H46O4
C35H52O6
C28H34O15
C29H36O15
C28H40O4
C30H46O4
C35H52O5

These study have led to the isolation and identified 78 constituents present in Lantana camara (yellow – pink taxa) leaves.

References

1.  Begun S, Mohammad BS. and SS Siddiqui 1995, Triterpenoids from the aerial parts of Lantana camara. J. Nat. Prod. 58: p.1570-1574.

2.  Deena . MJ and JE . Thoppil 2000, Antimicrobial activity of the essential oil of Lantana camara. Fitoterapia. 71(4): p.453-455.

3.  Louw P.G.J. 1943, Onderstepoort J. Vet. Sci. Animal Ind., 18, p.197.

4.  Saksena . N AND HH . Tripathi 1985, Plant volatiles in relation to fungistasis. Fitoterapia. 56: p243-244.

5.  Sharma . S, Singh . A and OP. Sharma 1999, An improved procedure for isolation and purification of lantadene A, the bioactive pentacyclic triterpenoids from Lantana camara leaves. J. Med. Aromatic Plant Sci., pp.686-688.

6.  Singh .R and A. Mishra 2008, Inhibitory effect of Lantana camara leaf extract on growth of Parthenium hysterophorus L. Life Sciences Bulletin, 5(2): p156-158.

7. Wahab A . 2004, Studies on the chemical constituents of Lantana camara L. Thesis.

International Center For Chemical Sciences University of Karachi, Karachi Pakistan .

21
22
23
24
25
26
27
28
28
29
30
31
32
33
34
35
36
37
/ 22 - Dimethyl- acryloxy-3 - hydroxyolean-12-
en-28-oic acid
(reduced lantadene B)
22 – Dimethylacry-
loyloxylantanolic acid
22 - Dimethyl-
acryloyloxylantic acid
Dipentene
Eugenol
Farnesol
Furfural
Geraniol
Glucose
Hispidulin
- Hydroxybenzoic acid
22 – Hydroxy-3- oxo-
olean-12-en-28-oic acid
Icterogenin
Isonuomioside A
Isoverbascoside
Lancamarone
Lantabetulic acid
Lantadene A / C35H54O5
C35H52O6
C35H52O6
C10H16
C10H12O2
C15H26O
C5H4O2
C10H18O
C6H12O6
C16H12O6
C7H6O3
C30H46O4
C35H52O6
C28H34O15
C29H36O15
C28H40O4
C30H46O4
C35