Study Guide for Chapter 5 in Fox

Glycolysis

  1. Define: metabolism, catabolism, & anabolism
  2. Glucose is catabolized in 3 stages. Name these.
  3. What does “glycolysis” mean? Where in the cell does this process occur?
  4. What happens to glucose immediately as it enters a cell?
  5. Glucose could be stored in a cell as a molecule of ______
  6. In what 2 tissues is this storage most likely tooccur?
  7. If glucose-6-P is to be broken down (catabolized), It is 1st converted into______
  8. Be able to summarize the process of glycolysis, including the products from some of the intermediary steps, and the end products as I did on the board.
  9. How many ATPs were used? How may ATPs did we gain?
  10. How many reduced NADs did we gain?
  11. Why is lactic acid produced sometimes?
  12. Of what benefit is lactic acid production to glycolysis?
  13. Is lactic acid a carbohydrate? Why?
  14. Be able to define: glycogenesis, glycogenolysis, and gluconeogenesis
  15. Be able to describe the over-all process of the “Cori Cycle”.
  16. What was the error in Fig. 5.5 that I pointed out to you?

Aerobic Respiration

  1. What does Aerobic mean?
  2. What organelle does the 3-carbon, pyruvic acid enter?
  3. What happens during what I call the “Pre-Krebs”?
  4. Acetyl-CoA binds to what other molecule at the start of the Krebs Cycle?
  5. What are the other 2 names for the Krebs Cycle?
  6. Be able to summarize what happens during the cycle and what we get out of it.
  7. Be able to summarize what happens during “Electron Transport and Oxidative Phosphorylation”.
  8. What is the “Final Electron Acceptor”? What is the “End Product” in Electron Transport?
  9. How many ATPs result from the oxidation of one reduced NAD? Form reduced FAD?
  10. How many ATPs do we get when one molecule of glucose is completely oxidized?
  11. What are “Free radicals” and “Antioxidants”?
  12. What is the name of the process by which the ATPs are actually generated within the mito?
  13. Be able to write the over-all equation involving the oxidation of glucose.

Metabolism of Lipids and Proteins

  1. What do “Lipogenesis and Lipolysis” mean?
  2. Understand the process of “Beta-Oxidation”. What are its main products?
  3. What happens to these products?
  4. What are “Ketone Bodies”? Where do they come from?
  5. What are the 3 steps in the catabolism of a polypeptide as I outlined on the board?
  6. What happens to the amino group? What does it become?
  7. Define: “Essential Amino Acids”? How many are there? Why are they “Essential”?
  8. What does “Transamination” mean? What is its significance?
  9. What is the preferred energy source for the: Brain? Resting Skeletal Muscle?
  10. What does the term “glucose sparing” mean? What is its significance?
  11. What is the “Key” molecule for most of the metabolic pathways? (Fig 5.17)