Rajiv Gandhi University of Health Sciences, Karnataka s24

DISSERTATION - SYNOPSIS

DR SIDDHARTH KRISHNAN

POST GRADUATE STUDENT

DEPARTMENT OF CONSERVATIVEDENTISTRY

AND ENDODONTICS

A.J. INSTITUTE OF DENTAL SCIENCES, KUNTIKANA,

MANGALORE.

BATCH 2011-2012

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, BANGALORE, KARNATAKA

ANNEXURE II

PERFORMA FOR REGISTRATION OF SUBJECTS FOR DISSERTATION

1. / Name of the Candidate
And Address
(in block letters) / SIDDHARTH KRISHNAN
C/21 RESHAM,7 BUNGLOWS
ANDHERI WEST,
MUMBAI – 400061
2. / Name of the institution / A.J. INSTITUTE OF DENTAL SCIENCES,
N.H-17, KUNTIKANA,
MANGALORE-575004
3. / Course of study and subject / MASTER OF DENTAL SURGERY, CONSERVATIVE DENTISTRY AND ENDODONTICS.
4. / Date of admission to course / 20/4/2011
5. / Title of the topic: / INFUENCE OF CARBAMIDE PEROXIDE BASED BLEACHING AGENTS ON THE BOND STRENGTH OF RESIN-ENAMEL/DENTIN INTERFACES
6. / Brief resume of the intended work:
6.1 Need for the study:
Carbamide Peroxide is a common at home bleaching technique used by patients.Carbamide Peroxide dispensed at various concentration from 10% – 35%. These bleaching agents are likely to destroy the hybrid layer at the Resin-Enamel-Dentin interfaces and varying results have been reported.Hence the need for the study.
6.2 Review of literature:
1.  DCBarcellos, VVB Fernandes Junior,MC Valera, P Benetti.
EffectOfCarbamide Peroxide Bleaching Gel Concentration On The Bond Strength Of Dental Substrates And Resin Composite.
Operative dentistry 2010;35(4):463-469.
This study evaluated the effect of bleaching gel containing 10%,15%,20% Carbamide Peroxide on the bond strength of dental enamel or dentin and resin composite restorations.They concluded that the bond strength of the restoration to enamel and the restoration to dentin were influenced by the application of Carbamide Peroxide and was dependent on its concentration in the bleaching gel.
2.HakanBulut,MuratTurkun, AysegulDemirbas Kaya, Effect of an oxidizing agent on the shear bond strength of brackets bonded to bleached human enamel. American journal of orthodontics anddentofacialorthopaedics 2006;129(2):266-272.
The purpose of this study was to investigate the effect of antioxidant treatment and delayed bonding on the shear bond strength of metal brackets bonded with composite resin to human enamel after bleaching with CarbamidePeroxide.They concluded that bleaching with 10% Carbamide Peroxide immediately before bonding reduces the bond strength of composite resin to enamel.Treating the bleached enamel surface with 10% sodium ascorbate or waiting reverses the reduction.
3.Rogerio de oliveira, Adriana Franco PaesLeme,Marcelo Giannini , Effect of a Carbamide Peroxide bleaching gel containing calcium or fluoride on human enamel surface microhardness. Brazillian dental journal 2005;16(2):103-106.
This in vitro study evaluated the surface microhardness of human enamel submitted to bleaching with 10%Carbamide Peroxide containing calcium or fluoride.They concluded that inspite of the addition of calcium and fluoride,all bleaching treatments affected the enamel surface microhardness.
4.Mortazaviv,Fathi MH ,AtaeiE,Khodaeian N. The Effect of 15% Carbamide Peroxide bleaching on the shear bond strength of composite to enamel.Shirazuniv dent journal.2009;9(1):24-30
The purpose of this study was to evaluate the effect of Carbamide Peroxide bleaching on the shear bond strength of composite to bleached enamel bonded with a three step total etch system;scotchbond multipurpose ,and two simplified all-in-one system Prompt L-pop and I bond.They concluded that the bleaching with 15%Carbamide Peroxide used in this study reduced the bond strength of the composite to the enamel bonded with a Three step total etch and Two simplified one step all-in-one dental bonding agents.
5.AF Lima, RT Sasaki ,LS Araujo, LA Gaglianone, MS Freitas, FHB Aguiar, GM Marchi. Effect of tooth bleaching on bond strength of enamel-dentin cavities restored with silorane and dimethacrylate –based materials. Operative dentistry 2011;36(4):390-396.
The aim of this study was to evaluate the influence of tooth bleaching on the push out bond strength of a composite resin based on dimethacrylates and silorane to cavities that involves both enamel and dentin.They concluded that bleaching treatment did not significantly affect the bond strength to either restorative system to enamel-dentin.Regardless of the bleaching treatment, Dimethacrylate-based resin systems exhibited significantly higher bond strengths to enamel-dentin than did the silorane-based system.
6.VanessaCavalli,MarceloGiannini,Ricardo M Carvalho. Effect of Carbamide Peroxide bleaching agent on tensile strength of human enamel . Dental Materials 2004;20:733-739.
The aim of this study was to evaluate the effect of low concentration of Carbamide Peroxide bleaching agent on the ultimate tensile strength of the enamel. They concluded that the specimen subjected to the bleaching regime presented significantly lower ultimate tensile strength than the control group.No difference were found among the type and concentration of the bleaching agent.
6.3 Objectives of the study:
The Objective of the study is to determine the variation in bond strength values with 35% Carbamide Peroxide in comparisonto conventional 10% Carbamide Peroxide.
7 / Material and methods:
7.1 Source of data:
80 freshly extracted non carious human molars were collected,not less than one month from the start ofthe experiment, from the Department of Oral and Maxillofacial Surgery, A.J.Institute of Dental Sciences and from private dental clinics in and around Mangalore and were surfaced adhering to CDC infection control protocols global.
7.2 Methods of collection of data(including sampling procedure,if any)
Selection Teeth:
80 freshly extracted teeth were randomly divided in two experimental groups(Enamel-E,Dentin-D) in which the samples were further divided into one control subgroup and four experimental subgroups consisting of 8 teeth each.

Methodology:
A flexible diamond disc attached to a handpiece was used to cut the roots from the teeth 2 mm apically to the cemento-enamel junction.80 freshly extracted teeth were randomly divided in two experimental groups (Enamel-E,Dentin-D) in which the samples were further divided into one control subgroup and four experimental subgroups consisting of 8 teeth each according to the carbamide peroxide concentration used in the whitening treatment.
·  GS :control subgroup,specimen stored in artificial saliva
·  G10 :Bleaching with opalescence P F 10%
·  G15 : Bleaching with opalescence P F 15%
·  G20: Bleaching with opalescence P F 20%
·  G35: Bleaching with opalescence P F 35%
The surfaces of all the specimens were etched with 37%phosporic acid for 15 seconds in dentin and 30 seconds in enamel and washed with air water spray for 40 seconds.Subsequently the adhesive resin was applied to the treated surfaces and light activated.Nanocomposite resin Filtek Z350(3M ESPE)was applied to the prepared enamel and dentin surfaces using a divided teflon mold with an internal dimension of 4×4×4 mm. Carbamide peroxide bleaching gels were applied directly to the bond interface of the specimens daily for 6 hours for 14 days.Finally the specimens were subjected to shear bond strength study under INSTRON machine (universal testing machine) where they were aligned in the holding device called Jig and subjected to load.The shear bond strength was noted by the mercury level alongside the scale. The maximum shear bond strength was noted at the time of fracture (de-bonding) of the restorative material. The results were statistically analyzed using ANOVA &Tukey’s Test.
7.3 Does the study require any investigations or interventions to be conductedon patients or other humans or animals? If so, pleasedescribe briefly.
Not Applicable.
7.4 Has ethical clearance been obtained from your institution in case of 7.3?
Obtained
















8. / List of references:
1.DCBarcellos,VVB Fernandes Junior, MC Valera, P Benetti.
Effect Of Carbamide Peroxide Bleaching Gel Concentration On The Bond Strength Of Dental Substrates And Resin Composite.
Operative dentistry 2010;35(4):463-469.
2.HakanBulut,Murat Turkun, AysegulDemirbas Kaya, Effect of an oxidizing agent on the shear bond strength of brackets bonded to bleached human enamel. American journal of orthodontics and dentofacialorthopaedics 2006;129(2):266-272.
3.Rogerio de oliveira, Adriana Franco PaesLeme, Marcelo Giannini , Effect of a Carbamide Peroxide bleaching angel containing calcium or fluoride on human enamel surface microhardness. Brazillian dental journal 2005;16(2):103-106.
4.Mortazavi v, Fathi MH , Ataei E, Khodaeian N. The Effect of 15% Carbamide Peroxide bleaching on the shear bond strength of composite to enamel.Shirazuniv dent journal.2009;9(1):24-30
5.AF Lima, RT Sasaki ,LS Araujo, LA Gaglianone, MS Freitas, FHB Aguiar, GM Marchi. Effect of tooth bleaching on bond strength of enamel-dentin cavities restored with silorane and dimethacrylate –based materials. Operative dentistry 2011;36(4):390-396.
6.VanessaCavalli, Marcelo Giannini, Ricardo M Carvalho. Effect of Carbamide Peroxide bleaching agent on tensile strength of human enamel . Dental Materials 2004;20:733-739.
9. / Signature of candidate
10. / Remarks of the guide:
11. / Name & Designation of
(in block letters):
11.1 Guide: / DR B SURESHCHANDRA
PRINCIPAL, PROFESSOR ,
DEPARTMENT OF CONSERVATIVE DENTISTRY AND ENDODONTICS
11.2 Signature:
11.3 Co-Guide (if any)
11.4 Signature:
11.5 Head of Department / DR RAJARAM NAIK
PROFESSOR AND HOD,
DEPARTMENT OF CONSERVATIVE DENTISTRY AND ENDODONTICS.
11.6 Signature
12. / 12.1 Remarks of the
Chairman & Principal: / DR B SURESHCHANDRA
12.2 Signature