Prof. Dr. Jeroen Krijgsveld

Prof. Dr. Jeroen Krijgsveld

German Cancer Research Center (DKFZ), Division Proteomics of Stem Cells and Cancer & Heidelberg University Medical Faculty

Im Neuenheimer Feld 581

69120 Heidelberg

Phone: +49-6221-421720

E-mail:

Education

1994 – 1999PhD, Dept. of Medical Microbiology, University of Amsterdam, The Netherlands

1988 – 1994MSc in Molecular Sciences, Wageningen University, The Netherlands

Employment

2016-Full Professor, German Cancer Research Center (DKFZ), Division Proteomics of Stem Cells and Cancer, & Heidelberg University Medical Faculty, Cluster of Excellence CellNetworks

2008-2015Research Team Leader and Head of the Proteomics Core Facility, EMBL, Heidelberg.

2004-2008Assistant professor, Dept. of Biomolecular Mass Spectrometry, Utrecht University, The Netherlands

2003NWO Genomics Fellow at Harvard Medical School, Dept. Cell Biology, Boston (with Prof. Steven Gygi)

2000-2003Post-doc, Dept. of Biomolecular Mass Spectrometry, Utrecht University, The Netherlands (with Prof. Albert Heck)

1999-2000Post-doc, Dept. of Pharmacology and Pathophysiology, Utrecht University, The Netherlands

Key publications

Rafiee M.-R., C. Girardot, G. Sigismondo, J. Krijgsveld. Expanding the circuitry of pluripotency by selective isolation of chromatin-associated proteins. Mol Cell 64(3):624-635; PMID: 27773674

Virant-Klun, I., S. Leicht, C. Hughes, and J. Krijgsveld. 2016. Identification of maturation-specific proteins by single-cell proteomics of human oocytes. Molecular & cellular proteomics 15:2616-27. PMID: 27215607

Cabezas-Wallscheid, N., D. Klimmeck, J. Hansson, D.B. Lipka, A. Reyes, Q. Wang, D. Weichenhan, A. Lier, L. von Paleske, S. Renders, P. Wunsche, P. Zeisberger, D. Brocks, L. Gu, C. Herrmann, S. Haas, M.A. Essers, B. Brors, R. Eils, W. Huber, M.D. Milsom, C. Plass, J.Krijgsveld*, and A. Trumpp*. 2014. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell. 15:507-522. PMID: 25158935

Hughes, C.S., S. Foehr, D.A. Garfield, E.E. Furlong, L.M. Steinmetz, and J. Krijgsveld. 2014. Ultrasensitive proteome analysis using paramagnetic bead technology. Molecular Systems Biology. 10:757. PMID: 25358341

Eichelbaum, K., and J. Krijgsveld. 2014. Rapid temporal dynamics of transcription, protein synthesis, and secretion during macrophage activation. Molecular & cellular proteomics 13:792-810. PMID: 24396086

Hansson, J., M.R. Rafiee, S. Reiland, J.M. Polo, J. Gehring, S. Okawa, W. Huber, K. Hochedlinger, and J. Krijgsveld. 2012. Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. Cell Reports. 2:1579-1592. PMID: 23260666

Eichelbaum, K., M. Winter, M. Berriel Diaz, S. Herzig, and J. Krijgsveld. 2012. Selective enrichment of newly synthesized proteins for quantitative secretome analysis. Nature Biotechnology. 30:984-990. PMID: 23000932

Van Hoof, D., J. Munoz, S.R. Braam, M.W. Pinkse, R. Linding, A.J. Heck, C.L. Mummery, and J. Krijgsveld. 2009. Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell. 5:214-226. PMID: 19664995

Van Hoof, D., M.W. Pinkse, D.W. Oostwaard, C.L. Mummery, A.J. Heck, and J. Krijgsveld. 2007. An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics. Nature Methods. 4:677-678. PMID: 17762871

Krijgsveld, J., R.F. Ketting, T. Mahmoudi, J. Johansen, M. Artal-Sanz, C.P. Verrijzer, R.H. Plasterk, and A.J. Heck. 2003. Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Nature Biotechnology. 21:927-931. PMID: 12858183