BIOCHEMISTRY II
BIOENERGETICS AND METABOLISM
BGY C13S
2005/2006
GENERAL INSTRUCTIONS
PROFESSOR: J.W. GURD
OFFICE: S532
OFFICE HOURS: MONDAY AND THURSDAY, 9:15-10:15 A.M.
(or whenever you can find me!)
LECTURE : Room SW319; WEDNESDAY: 12-2 p.m. FRIDAY: 11-12a.m.
Telephone: 287-7410
E-mail: .
Texts:
· Principles of Biochemistry, 4th edition, Horton, Moran,Perry and Rawn (2006)
· The Biochemistry Student Companion, A.J. Scism, 3rd edition 2006
· Reserve: The following books should be on course reserve:
Voet, Voet and Pratt Fundamentals of Biochemistry
Rawn Biochemistry
Zubay Biochemistry
Stryer Biochemistry
Garrett and Grisham Biochemistry
Each of these texts contain similar information. However, you may find that reading a slightly different presentation of the same basic material will help to clarify difficult concepts.
A number of additional biochemistry texts and sources are also available in the library.
Marking scheme:
Exam / Material / Date / % of final gradeQuiz
1 hr / bioenergetics / Feb 3 / 10
mid-term
2 hours / bioenergetics, electron transport, carbohydrate chemistry, glycolysis, TCA cycle / TBA / 30
Final
3 hours / All course material / TBA / 60
* Note that the final exam may be held on Friday evening or Saturday morning.
The quiz will be 50 minutes in duration and held during class time. The midterm will be 2 hours, and the final 3 hours long. Quizzes and exams will have a multiple choice format.
Marks will be posted on the web and can be accessed via the course web page. It is each student’s responsibility to check her/his grade and to resolve any problems within 1 week of the posting.
There will be NO makeup for the quiz. If the quiz is missed and a valid reason (medical certificate or other) is provided, the 10% allotted to the quiz will be added to the midterm. Student’s who miss the midterm must provide valid documentation (medical certificates will be verified) and inform Dr. Gurd before the exam or within 48 hours of the exam.Students must use the UTSC medical form. If required, a makeup will be held within 3-5 days of the initial examination.There will be only 1 makeup exam for the midterm. For students who miss both the midterm and the makeup, a special final exam will be written that will be worth 90% of the final grade. Student’s who miss the final exam must petition for permission to write a makeup exam, which will be held at the end of the summer examination period (see calendar).
Office hours:
Dr. Gurd’s office is room S532. Office hours are Monday and Thursday mornings from 9:15-10:15a.m.. Appointments outside these hours can be arranged, or simply drop by the office. I will do my best to make time to meet with you. Be prepared and consult the text prior to coming to the office.
I will answer e-mail, but will give only short answers. Yes or No preferred. Questions requiring longer, more involved answers should be addressed to me in person during office hours, after class, or whenever else you can find me.
DO NOT FALL BEHIND!
METABOLISM IS VERY INTERESTING, BUT THERE IS A LOT OF MATERIAL AND IT CAN BECOME OVERWHELMING IF YOU LET THE WORK ACCUMULATE.
COURSE OBJECTIVES:
By the end of this course you should:
~ Understand the overall framework of metabolism
and have a general knowledge of how it is
regulated
~ Understand the concepts of free energy and redox
potential in relation to metabolism
~ Understand the central importance of ATP in energy
currency
~ Know the mechanisms involved in the synthesis of ATP
~ Be familiar with the key steps in the main pathways of
carbohydrate, fat and lipid metabolism, nitrogen metabolism, their regulation
and their physiologic and pathologic significance
~ Understand the switches in metabolic pathways during
feeding and fasting
~ Appreciate the important roles of hormones in
regulation of metabolism
~ Be familiar with the main concepts of transmembrane
signaling
~ Be able to apply your knowledge of metabolism to your
understanding of health & disease