Table I: Evaluation Studies of β-Cyclodextrin Complexes of CDF

Code / Method / Complexing Agent Used / Ratio / Solubility (mg/ml)
CDF / - / - / - / 0.014
CDFCD / Kneading / β-cyclodextrin / (1:1) / 0.032
CDFCD / Kneading / β-cyclodextrin / (1:2) / 0.089


Table II: Infra-Red Assignments of β-Cyclodextrin (CD), CDF and CDFCD Spectra

IR Frequencies (cm-1)
CD / CDF / CDFCD
3377-3238 (O-H) / 3437-3315 (O-H) / 3373-3255 (O-H)
2924 (C-H) / 2933-2841 (C-H. OCH3) / 2928-2843 (C-H)
1330 coupled (C–C–H), (C–O–H),
(H–C–H) / 1627-1568 (C=C, C=O) / 1637-1570 (C=C, C=O)
1155 and 1078 (C–O), (C–C), (C–O–C) / 1429 (olefinic C-H) / 1429 (olefinic C-H)
1030 (O–C–H), (C–C–H), (C–C–O) / 1274 (C-F) / 1332 coupled (C–C–H), (C–O–H), (H–C–H)
943 (skeletal vibration involving α-1,4 linkage) / 1184-1163 (aromatic C–O) / 1276 (C-F)
858 (C–C–H), (C–O), (C–C) from anomeric vibration / 1035-823 (C–O–C) / 1155 and 1078 (C–O), (C–C), (C–O–C)
1031 (O–C–H), (C–C–H), (C–C–O)
945 (skeletal vibration involving α-1,4 linkage)
844 (C–C–H), (C–O), (C–C) from anomeric vibration


Table III: Relative Intensities of β-Cyclodextrin, CDF and CDFCD

Β-Cyclodextrin / CDF / CDFCD
Peak position (2θ) / Intensity / Peak position (2θ) / Intensity / Peak position (2θ) / Intensity
10.7 / 1488 / 10.7 / 1203 / 10.7 / 1560
12.5 / 2705 / 12.4 / 1108 / 12.4 / 1973
17.1 / 1415 / 16.1 / 1517 / 12.5 / 2378
19.6 / 1484 / 17.1 / 2503 / 16.1 / 732
20.8 / 1375 / 19.4 / 1276 / 17.1 / 1297
22.8 / 1341 / 21.6 / 2081 / 19.4 / 841
23.2 / 1228 / 19.6 / 1601
24.7 / 3676 / 20.8 / 1135
25.0 / 2323 / 21.6 / 904
25.6 / 2546 / 22.8 / 1172
23.2 / 594
24.7 / 685
25.0 / 986
25.6 / 842

1