Postdoctoral Fellowship – CSOF4

Role summary for potential applicants

Advertised Job Title: / Postdoctoral Fellow – Using synthetic biology approaches to deliver improved health strategies.
Reference Number: / 38504
Classification: / CSOF4
Salary Range: / AU$81,055 - AU$88,787 plus up to 15.4% superannuation
Location: / Geelong, Victoria
Tenure: / Specified Term until June 2019
Relocation assistance: / Will be provided to the successful candidate if required.
Applications are open to: / Australian Citizens Only
Australian Citizens and Permanent Residents Only
 All Candidates
Functional Area: / Research Scientist / Engineer - Postdoc
% Client Focus - Internal: / 80
% Client Focus - External: / 20
Reports to the: / Research Scientist
Number of Direct Reports: / No direct reports
Role Overview:
Future Science Platforms are an investment in science that underpins innovation and that has the potential to help reinvent and create new industries for Australia. FSPs will see us grow the capability of new generation of researchers and allow Australia to attract the best students and experts to work with us on future science. They are strategic investments aimed at developing capacity in areas of identified future importance for Australia.FSPs are both impact and science focused, developing innovative scientific solutions with industry, government and university partners. They support world class, coherent and creative research teams which integrate science and delivery over the long term, looking to the future science needs of CSIRO and our partners with a 5 to 10 year vision.
To position Australia to build a vibrant synthetic biology research and development community to support the bio-based industries and ecoengineering activities of tomorrow, CSIRO has established the Synthetic Biology FSP (SynBioFSP). Synthetic Biology (SynBio) is the design and construction of biological parts, devices, and organisms (usually based on DNA-encoded componentry); and their application for useful purposes. The SynBioFSP has a mission to develop capacity in synthetic biology within CSIRO and across Australia, in a collaborative and transparent manner. Science capability will be strongly aligned with CSIRO business unit capabilities and will allow CSIRO to deliver novel future outcomes for external partners. The program has a $13 million funding envelope over the first three years. We aim to:
  1. Build the foundational capabilities to advance SynBio research, including significant investment in social licence to operate
  2. Drive national coordination by making these foundational capabilities widely available to the broad research community, governments, and industry for the development of novel industrial products, pharma, biocontrol agents, and strategies for building ecosystem resilience to environmental change, and
  3. Build strong partnerships, collaborations, and connections across the innovation sector to develop these novel products and applications responsibly.
The Synthetic Biology FSP (SynBioFSP) is developing a research portfolio which will be spread across CSIRO and a wide variety of partner organisations (universities, industry, NGOs, other research organisations, etc.), both national and international. The research portfolio is dynamic and will evolve over time on the basis of strategy and performance.Research projects will sit within one or more priority Application Domains (Environment & Biocontrol, Chemicals & Fibres, Organelles & Endosymbionts) and one or more Science Domains (Integrative Biological Modelling, Engineering Novel Biological Components, Assembling Novel Biosystems, Maximising Impact). The SynBio FSP will embed a social and behavioural science agenda to address issues around social licence to operate.
Postdoctoral Fellowships at CSIRO provide opportunities to scientists and engineers, who have completed their doctorate and have less than three years relevant postdoctoral work experience. These fellowships will help launch their careers, provide experience that will enhance their career prospects, and facilitate the recruitment and development of potential leaders for CSIRO.
Postdoctoral Fellows are appointed for up to three years and will work closely with a leading Research Scientist or Engineer in their respective field. They carry out innovative, impactful research of strategic importance to CSIRO with the possibility of novel and important scientific outcomes in collaboration with others. They present the findings in appropriate publications and at conferences nationally and internationally.
The Postdoctoral Fellow will be based at the CSIRO Australian Animal Health Laboratory (AAHL), a high-containment facility designed to allow scientific research into the most dangerous infectious agents in the world. The postdoctoral fellow will work across CSIRO research groups with expertise in synthetic biology, immunology and molecular biology and will be joining an active research team consisting of multiple post-doctoral fellows, students and technicians. The candidate will have a unique opportunity to work on a multidisciplinary project using novel genetic technologies applied to emerging viral pathogens of global importance. The candidate will gain valuable experience and training working in both SynBio and Immunology research at AAHL in a world class biocontainment facility. Successful completion of this project has the potential to make a major contribution to the global control of viruses of significance. They will also have access to multiple training opportunities to build their scientific career. This project provides an opportunity to help develop a new, state-of-the-art research program in CSIRO.
Duties and Key Result Areas:
  • Use gene manipulation tools, such as siRNAs/CRISPRs, to silence/delete genes.
  • Contribute to the development of a GeCKO screen to identify important genes.
  • Use bioinformatics approaches to investigate the implications of gene manipulation and assess candidate genes.
  • Perform validation studies in preparation for scale-up and production trials.
  • Carry out innovative, impactful research of strategic importance to CSIRO that will where possible lead to novel and important scientific outcomes.
  • Undertake regular reviews of relevant literature and patents.
  • Produce high quality scientific and/or engineering papers suitable for publication in quality journals, for client reports and granting of patents.
  • Prepare appropriate conference papers and present those at conferences as agreed with your supervisor.
  • Contribute to the development of innovative concepts and ideas for further research.
  • Make a contribution to the effective functioning of the research team and help deliver CSIRO’s organisational objectives and plans.
  • Work collaboratively with colleagues within your team, the business unit and across CSIRO.
  • Communicate effectively and respectfully with all staff, clients and suppliers in the interests of good business practice, collaboration and enhancement of CSIRO’s reputation.
  • Adhere to the spirit and practice of CSIRO’s Values, Health, Safety and Environment plans and policies, Diversity initiatives and Zero Harm goals.
  • Undertake an appropriate training and development program developed by CSIRO.
  • Other duties as directed.
CSIRO’s postdoctoral training programis developed between the Postdoctoral Fellow and a CSIRO scientist. The program will focus on enhancing the Fellows’ capabilities to the level expected of an independent researcher and will include on-the-job and course-based development encompassing:
  • Discipline-specific techniques and protocols
  • Professional growth
  • Project management
  • Communication and influencing skills
  • Working and collaborating with others

Selection Criteria:
Under CSIRO policy only those who meet all essential criteria can be appointed
Pre-Requisites:
  • Education/Qualifications: A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as molecular biology, cell biology or immunology.
Please note: To be eligible for this role you must have no more than 3 years of relevant postdoctoral experience.
  • Communication: High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including at national and international conferences.
  • Publications: A record of publications in quality, peer reviewed journals.
  • Collaboration: A history of professional and respectful behaviours and attitudes in a collaborative environment.
Essential Criteria:
  1. Demonstrated track record in molecular biology techniques, including PCR, qRT-PCR, gene cloning, sequencing, CRISPR/Cas9 genome editing and a knowledge of GeCKO screening techniques;
  2. Demonstrated experience in sterile tissue culture;
  3. Demonstrated experience in immunoassays, such as flow cytometry, ELISA and Western blot;
  4. Demonstrated ability to work independently under minimal supervision while contributing to overall team performance and proven ability to meet performance deadlines during the course of the project;
  5. A desire to carry out innovative, impactful research that will lead to novel and important scientific outcomes.
Desirable Criteria:
  1. Experience in innocuity testing
  2. Demonstrated experience in bioinformatics analysis of next generation sequencing data;
  3. Demonstrated experience in virology methods, e.g. virus culture, TCID50;
  4. Demonstrated experience in host-pathogen interaction analysis;
  5. Research experience in disease models.
CSIRO Values:
As Australia’s Innovation Catalyst, CSIRO has strategic actions underpinned by behaviours aligned to:
  • Excellence in science,
  • Inclusion, trust & respect,
  • Health, safety & environment
  • Deliver on commitments.
In your application and at interview you will need to demonstrate alignment with these behaviours.
To be appointed as a Postdoctoral Fellow within CSIRO, candidates are required to have submitted their PhD at the time of commencement, as a minimum requirement, if PhD conferment has not been obtained. If a candidate has submitted, but their PhD has not yet been formally attained, the starting salary will be CSOF4-1 which is AU$78,479. Upon CSIRO receiving written confirmation that the PhD has been awarded (within a six month period from commencement date), the salary will be increased to the negotiated level and the difference will be back-paid to the Officer’s start date.
Other special requirements:
Appointment to this role may be subject to conditions including security/medical/character clearance requirements. Applicants who are not Australian Citizens or Permanent Residents may be required to undergo additional security clearance processes; which may include medical examinations and an international standardised test of English language proficiency (i.e. IELTS test).-
This is a security assessed position. The successful applicant will currently hold, or have the ability to obtain, an Australian security clearance.
Security Assessment and Microbiological Security Requirements for Personnel Working on the Australian Animal Health Laboratory (AAHL) Site:
  • The nature of our work requires that each person working on site must comply with the conditions described below.
  • The appointee is required to pass a security clearance at a level appropriate to duties of the position. Confirmation of the appointment is subject to obtaining that clearance.
  • It is essential that all work on exotic or emerging diseases carried out at AAHL is conducted in a safe manner to prevent the escape of the disease agents used, and to this end, all activities and personnel will be subject to appropriate microbiological security measures. Consequently, while working at AAHL, you may not reside on a property on which are kept any of the following animals: sheep, cattle, pigs, goats, horses, asses and mules, any other cloven-hoofed animal, fowls, turkeys, geese, domestic ducks, caged birds, emus or ostriches. Personnel working with diseases of aquatic animals may not keep aquarium fish at their place of residence and personnel working with cane toad material must avoid contact with amphibians.
  • In addition, for a period of seven days after working in the microbiologically secure area of AAHL, personnel may not have close contact with any of the above animals, amphibians or birds or the actual places where these animals are held, or visit any aquatic animal farm or aquatic animal hatchery.
  • Working in the barrier maintained Small Animal Facility requires avoidance of additional animals such as mice, rats, guinea pigs, rabbits and poultry 3 days prior to arrival.
  • It is usual practice in laboratories where work with infectious disease agents is carried out, to collect a blood sample from personnel and store serum for future reference. This is a safety precaution, so that if any person becomes ill in the future, serum samples are available for testing.
  • Personnel must abide by Occupational Health, Safety and Environment regulations. Safety signs and directives issued by CSIRO personnel must be complied with at all times.
  • Access restrictions apply to the Werribee Animal Health Facility (WAHF) site that is associated with, but remote from, the AAHL site.
Additional information detailing AAHL's micro-security restrictions can be found at it:

Other Information:
How to Apply
Please apply for this position online at You will need to upload your cover letter and resume/CV as ONE document, expressing your interest in the role and addressing each of the Selection Criteria. Please provide sufficient relevant information to enable the selection panel to assess your suitability against the Selection Criteria. Should your application proceeds to the next step, you may be asked to provide additional information.
If you experience difficulties applying online call 1300 984 220 and someone will be able to assist you. Outside business hours please email:
Referees: If you do not already have the names and contact details of two previous supervisors or academic/ professional referees included in your resume/CV please add these before uploading your CV.
Contact: If after reading the selection documentation you require further information please contactAndrew Bean by email by phone at+613 5227 5000.
About CSIRO
Australia is founding its future on science and innovation. Its national science agency, the Commonwealth Scientific and Industrial Research Organisation (CSIRO) is a powerhouse of ideas, technologies and skills for building prosperity, growth, health and sustainability. It serves governments, industries, business and communities across the nation.
Find out more!
About the SynBio FSP Future Science Platform
For more information, see theSynthetic Biology FSP website.
CSIROHealth & Biosecurity: This business unit collaborates with government, industry, universities and other international agencies to make a difference and protect the things we value most - the health of our people, economy, industries and environment - from biosecurity threats. For more information please see Health & Biosecurity.
What CSIRO offers you
This multidisciplinary project is a unique opportunity for the postdoc to work at the convergence of biology, chemistry and surface chemistry. The appointment will be able to expand their expertise into all these areas and bring together scientists from each discipline.
The postdoctoral fellow will benefit from the intellectually stimulating environment provided by the host laboratories, and have access to state of the art facilities and equipment.
The postdoc would have the opportunity to benefit from mentorship from key high-calibre scientists within the project, both within CSIRO and internationally.
Ongoing international interest in this area will ensure the opportunity for the postdoc to publish in high calibre internationally recognised journals and to travel to, and present at, international conferences. The postdoc will have access to training programs both within and external to the organisation (e.g., project management or technical development).
The grounding in this area of research will enhance the postdoc's career, making them highly employable beyond this postdoctoral experience.
The postdoc will be free to identify and explore new IP in this area and work with CSIRO's BD&C to develop a commercialisation plan for this highly sought after technology.