Participation of the research staff of SBCG in international conferences or short term training events.

Research staff of SBCG attended the following international conferences or short term training events where they presented SBCG’s research work:

  1. Dr. D.D. Leonidas. 25th European Crystallographic Meeting, 16 – 21August 2009, Istanbul, Turkey. Title of poster presentation: The binding of pyrimidinyl phosphonucleotide inhibitors to bovine seminal ribonuclease Leonidas, D.D., Dossi, K. Hayes, J.M., Tsirkone, V., Matoušek, J., Poučková, P., Souček, J., Zadinova, M., and Zographos, S.E.Abstractsp. 147
  1. Spyros E. Zographos, Christina E. Drakou, Katerina E. Tsitsanou. 60th Hellenic Society of Biochemistry and Molecular Bilogy Conference. Athens 20-22 November 2009. Title of Poster presentation:Natural occurring flavonoids as potential antidiabetic agents: Structural, kinetic and computational analysis of chrysin in complex with Glycogen Phosphorylase.Keramioti M, Tsitsanou KE, Tiraidis C, Alexacou K-M, Mamais M, Drakou CE,Leonidas DD, Kato A, Oikonomakos NG, Hayes JM and Zographos SE. Abstracts, Vol. 55, p. 89
  1. Demetres D. Leonidas, Evangelia D. Chrysina, Josheph M. Hayes, Michalis Mamais. 4th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB09 NHRF, Athens, 18-20 December, 2009.

Titles of poster presentations: (1). Beta-D-glucose pyrimidine derivatives binding at the catalytic site of glycogen phosphorylase: the role of ligand ionization/tautomeric states. Michalis Mamais, J.M. Hayes, T. Gimisis, E.D. Chrysina (2). Structure based design of hypoglycaemic agents: in silico studies of 3'-substituted glucose derivatives as inhibitors of glycogen phosphorylase. C. Lamprakis, J.M. Hayes, D. Komiotis, D.D. Leonidas.

  1. Dr. S.E. Zographos. 3rd Swedish-Hellenic, Life Science Research conference 25–27 March 2010 Athens, Greece. Title of Oral presentation:Structural Studies of hCINAP: Αn atypical mammalian nuclear adenylate kinase with ATPase activity.
  1. Maria Dimarogona. InternationalSchool of Biological Magnetic Resonance: 9th Course. Biophysics and Structure to counter threats and challenges. 22 June – 2 July 2009, Erice, Sicely. Italy.Title of poster presentation:Structural Studies of new hemicellulases from the filamentous fungus F. oxysporum. Dimarogona M., Moukouli, M., Topakas, E., Christakopoulos, P., Chrysina, E.D. (2009).
  1. Evangelia D. Chrysina, Joseph M. Hayes, Michalis Mamais.3rd Hellenic Symposium on Organic Synthesis from chemistry to Biology Medicine and Materials Science, 15-17 October 2009. Titles of Poster presentations: (1). Looking for potent inhibitors of glycogen phosphorylase – the structure-based ligand design approach in vitro and in silico. Chrysina, E.D., Hayes, J.M., Mamais, M., Lazoura, E., Gimisis, T. Abstract book L07, pg.37 (2). Molecular modelling of β-D-glucose pyrimidine derivatives binding at the catalytic site of glycogen phosphorylase.Mamais, M., Hayes, J.M., Gimisis, T., Chrysina, E.D. Abstract book P55, pg.115 (3). Glucopyranosylidene-spiro-oxathiazoles: an optimized class of potential glycogen phosphorylase inhibitors for the structure-based design of new hypoglycemic agents.Skourti, P.V., Alexacou, K-M., Vidal, S., Czifrak, K., Nagy, V. Berzsenyi, E., Praly, J-P, Somsak, L., Siafaka-Kapadai, A., Chrysina, E.D.
  1. Spyros E. Zographos, Demetres D. Leonidas, Evangelia D. Chrysina, Vassiliki T. Skamnaki, Katerina E. Tsitsanou, Christina. E. Drakou, Vassiliki Tsirkone, Maria Dimarogona, Magda Chegkazi, , Aikaterini Chajistamatiou, Dionisis Markopoulos & Evdoxia Mastroleon. 5th Conference of the Hellenic Crystallographic Association, University of Thessaly, 24-25 September 2010, Larisa, Greece.

Titles of Oral presentations: (1). Natural flavonoid Catechin inhibits Glycogen phosphorylase by binding at new allosteric site. V.T. Skamnaki, M. Savvidou, A. Katsandi, A.-M. Psarra, M. Kontou, D. Kouretas, D.D. Leonidas.Abstract Book p. 16. (2). Crystal structure of a new endo--1,4-xylanase from Fusarium oxysporum determined at 1.9 Å resolution.Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D. Abstract Book p. 18 (3). Refinement and Validation of Phosphorylase Kinase ATP-Binding Site Inhibitor Complexes using Molecular Dynamics and MM-GBSA calculations. J.M. Hayes, V.G. Tsirkone, V.T. Skamnaki, G. Archontis, S.E. Zographos, D. Komiotis, D.D. Leonidas. Abstract Book p. 37

Titles of poster presentations:(1). An overview of diabetes type 2 and glycogen phosphorylase inhibitors. How structure based drug design can prove a valuable therapeutic strategy. K.-M. Alexacou, S.E. Zographos, N.G. Oikonomakos, and D.D. Leonidas. Abstract Book p. 42 (2). Kinetic and crystallographic studies of glycogen phosphorylase in complex with D-glucopyrano-sylidene spiro-isoxazoline derivatives for the design of new antidiabetic drugs.Chajistamatiou, A., Goyard, D., Vidal., S., Praly, J-P., Siafaka-Kapadai, A., Chrysina, E.D.Abstract Book p. 46 (3).Kinetic and crystallographic studies of potential inhibitors of glycogen phosphorylase, a key enzyme for the treatment of type 2 diabetes. Chegkazi, M., Pantzou, A., Sovantzis, D., Hadjiloi, T., Cismas, C., Siafaka-Kapadai, A., Gimisis, A., Chrysina, E.D. Abstract Book p. 47 (4). Development of a software application for handling protein crystallization conditions and trials. Markopoulos, D., Manolakos, E., Chrysina, E.D. Abstract Book p. 52 (5). Development of an electronic laboratory notebook for structure-based drug design. Mastroleon, E., Manolakos, E., Chrysina, E.D.Abstract Book p. 53 (6). The crystal structure of rabbit muscle glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)guanidinoacetamide.Skourti, P.V., Loganathan, D. Siafaka-Kapadai, A., Chrysina, E.D.Abstract Book p. 57 (7). Kinetic and modeling studies of a new set of β-D-glucose pyrimidine derivatives binding at the glycogen phosphorylase catalytic site.V.G. Tsirkone, A. Katsandi, S. Manta, E. Tsoukala, J.M. Hayes, M. Kontou, D. Komiotis, D.D. Leonidas. Abstract Book p. 59 (8). AgamOBP1 is a molecular target for the development of novel insect repellents. K.E. Tsitsanou, C.E. Drakou, A. Thireou, E. Eliopoulos, K. Iatrou and S.E. Zographos. (Poster presentation) Abstracts, p.60.

  1. Evangelia D. Chrysina. International Graduate School in Molecular Medicine, Joint fall retreat with students of the University of Ulm, Germany. Organized by Prof. Dr. C. Vorgias & Prof. Dr. U. Knippschild. Biology Department, University of Athens, 24 September 2010. Title of Oral presentation: Chrysina, E.D: Structural basis of drug design.
  2. Demetres D. Leonidas. 8th RNase Congress, Naples – Italy October 20-22, 2010.Title of Oral presentation: Structure-assisted inhibitor design on Ribonucleases. Abstract Book p. 21.
  1. Evangelia D. Chrysina, Maria Dimarogona, Marianna D. Charavgi. 11th Panhellenic Symposium of Catalysis, University of Athens, 22-23 October 2010, Athens, Greece.Title of Oral presentation: Evangelia D. Chrysina: The role of glycogen phosphorylase in the biosynthesis of carbohydrates.Titles of Poster presentations: (1). The crystal structure of a new GH10 xylanase from Fusarium oxysporum determined at 1.9 Å resolution.Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D. (2). Crystallographic studies of glucuronoyl esterase from Sporotrichum thermophile – a novel biocatalyst for the plant biomass degradation.Charavgi, M-D, Dimarogkona, M., Moukouli, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.Book of Abstracts, pg, P39
  2. Evangelia D. Chrysina(representing Greece). Instruct meeting. End of preparatory phase for the ESFRI action Integrated Structural Biology in Europe, , Centro Nacional de Biotecnología – CNB, 7-8 February 2011, Madrid, Spain
  3. Evangelia D. Chrysina. () General Secretariat for Gender Equality, 3 May 2011, Karditsa, Greece. Title of Oral presentation:Marie Curie- Miraculous Chemistry
  4. Demetres D. Leonidas and Evangelia D. Chrysina.1st Summer School on Proteins, Department of Biology, National and Kaporistrian University of Athens, 1-2 July 2011, Athens, Greece. Titlesof oral presentations:(1). Demetres D. Leonidas: Sttructure guided drug design. (2). Evangelia D. Chrysina: From the knowledge of protein structure to the design of new leads.
  1. Spyros E. Zographos & Katerina E. Tsitsanou.Fifth International Meeting on "Molecular and Population Biology of Mosquitoes and Other Disease Vectors”, 24-30 July 2011, Kolymbari, Crete, Greece.Title of Oral presentation by Spyros E. Zographos: New Molecular Targets for the Structure-based Design of Novel Mosquito Repellents.
  1. Spyros E. Zographos & Katerina E. Tsitsanou. XXIst Congress of the European Chemoreception Research Organization (ECRO), September 7-10, 2011, Manchester, UK.Titles of poster presentations: (1). K.E. Tsitsanou, C.E. Drakou, S.E. Zographos. “Crystal structure of odorant binding protein 4 from Anopheles gambiae”;, XXIst Congress of the European Chemoreception Research Organization (ECRO), September 7-10, 2011, Manchester, UK, Abstracts, p.122. (2). K.E. Tsitsanou, T. Thireou, C.E. Drakou, K. Koussis, E. Eliopoulos, K. Iatrou, S.E. Zographos. “AgamOBP1 crystal complex with DEET: a new molecular target for the design of novel mosquito repellents. Abstracts, p.123.
  1. Demetres D. Leonidas, Evangelia D. Chrysina, , Athanassios Tartas, Vassiliki Tsirkone. 6th conference of the Hellenic Society for Computational Biology and Bioinformatics - HSCBB11, University of Patras Conference Centre, October 7-9, 2011. Titles of Oral presentetions: (1). Identification of glycogen phosphorylase catalytic site inhibitors exploiting the Zinc-Database and Consensus scoring docking. V. Tsirkone, D.D. Leonidas, J.M. Hayes. Proceedings p.45 (2). “Lakes”- an application for the detection of protein binding sites by solvent mapping. Athanassios Tartas & Evangelia D. Chrysina.
  1. Spyros E. Zographos, Demetres D. Leonidas, Evangelia D. Chrysina & Katerina E. Tsitsanou. International Workshop on Macromolecular Crystal Growth and Optimisation Methods 31 October - 3 November 2011 National Centre for Scientific Research “DEMOKRITOS”, Athens, Greece.

Titles of Oral presentations (1). Spyros E. Zographos: The purification of Proteins: Objectives and strategy, Choice of source, Purification methods (an overview of chromatographic methods), and protein purification examples. (2). Demetres D. Leonidas: High-throughput structure based drug design. (3). Evangelia D. Chrysina: Spot the difference” puzzle for a new xylanase of GH10 family; from crystallization to 3D structure

  1. Maria Dimarogona. EMBO Practical Course - Computational structural biology - from data to structure to function, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), 14-18 November 2011, Cambridge, UK.Title of Poster presentation:Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.
  1. Demetres D. Leonidas, Marianna D. Charavgi.62nd Meeting of Hellenic Society of Biochemistry & Molecular Biology, 9-11 December 2011, Athens.Titles of Poster presentations: (1). The 3D structure of a novel Glucuronoyl Esterase from Sporotrichum thermophile (StGE) at 1.55 Å. Charavgi, M.D., Dimarogona, M., Moukouli, M., Topakas, E., Christakopoulos, P., Chrysina, E.D. (2). C-5 Halogen substituted glucopyranosyl nucleosides as inhibitors of glycogen phosphorylase b. Structural, biochemical and biological assessment. Kantsadi A.L., Manta S., Skamnaki V.T., Hayes J.M., Kiritsis C., Psarra A.-M.G., Koutsogiannis Z., Dimopoulou A.,Theofanous S., Nikouleousakos N., Zoumpoulakis P., Kontou M., Zographos, S.E., Komiotis, D., and Leonidas, D.D. Abstract Book p. 255.
  2. Structure- & Computer-Aided Design Workshop: Bioactive Molecules & Materials, 7-11 November 2011, National Hellenic Research Foundation, Athens, Greece.Title of Oral presentation: J.M. Hayes: “Molecular Modeling Targetting Glycogenolysis Control”, J.M. Hayes, V.G. Tsirkone, V.T. Skamnaki, G. Archontis, S.E. Zographos, D. Komiotis, D.D. Leonidas
  3. Michalis Mamais. 21st Panhellenic Conference of Chemistry, 9-12 December 2011, Thessaloniki, Greece. Title of Oral presentation: 4-arylamino--D-glucopyranosyl-pyrimidines: Exploring the catalytic site of glycogen phosphorylase. Mamais, M., Chrysina, E.D., Gimisis, T.