On-Line Supplemental Material Tables (E) T-1 to T-5

Table (E) T-1 ICD9 Diagnostic and Procedure Codes Used for Cohort Identification

Diagnostic Codes / CCS / ICD-9-CM
Procedures:
CABG / 44 / 361.0 – .9, 362, 363.1, 363.2 and 363.0
CEA / 51 / 381.2
Diagnostic Codes:
Inclusion
Acute myocardial infarction / 100 / 410.0 – 410.92
Coronary artery disease / 101 / V458.1, V458.2, 411.0 – 414.89
Acute cerebrovascular disease / 109 / 433.01 – 434.91, 436
Cerebrovascular occlusions / 110 / 433.0 – 433.90
Other cerebrovascular diseases / 111 / 437.0, 437.1, 437.3 – 437.9
Transient ischemic attack / 112 / 435.0, 435.1, 435.3, 435.8, and 435.9
Cerebrovascular disease, late effects / 113 / 438 – 438.9
Exclusion
Acute cerebrovascular disease / 109 / 430, sub-arachnoid hemorrhage
431, intracerebral hemorrhage
432.0 – 432.9 extradural and subdural hemorrhage


Table (E) T-2 Additional Cohort Demographics

CEA / CABG / CEA and CABG / p
n=178,959 / n= 471,881 / same day
n=1230 / spacing unknown
n=5807
Race / Ethnicity*
White, non-Hispanic / 91.4% / 85.5% / 82.3% / 87.9%
African American / 4.2% / 6.2% / 4.8% / 5.3%
Hispanic / 2.6% / 4.6% / 6.6% / 3.9%
Asian – Pacific Islander / 0.6% / 1.2% / 1.6% / 08%
Native American / 0.2% / 0.3% / 0% / 0.2%
Other / 1.1% / 2.4% / 4.7% / 1.9%
Admission Type*
Emergency / 17.6% / 30.5% / 26.0% / 27.6%
Urgent / 17.8% / 29.5% / 24.1% / 30.1%
Elective / 64.6% / 39.8% / 49.4% / 41.8%
Primary payer / < .0001**
Medicaid / 3.0% / 4.6% / 3.4% / 4.0%
Medicare / 69.0% / 53.3% / 70.8% / 64.0%
Private and HMO / 24.7% / 36.6% / 23.8% / 27.4%
Self pay, no charge, and other / 3.3% / 5.5% / 2.0% / 4.5%
Discharge disposition / < .0001**
Home / 85.7% / 64.6% / 49.2% / 53.9%
Transfer to other short term hospital / 0.8% / 1.0% / 1.6% / 1.3%
Long term care facility / 4.4% / 8.2% / 23.6% / 12.2%
Home health and hospice / 5.8% / 20.2% / 20.8% / 21.8%
Alive, destination not known / 1.8% / 2.6% / 0% / 4.8%
Died in-hospital / 1.3% / 3.4% / 4.7% / 5.8%

* Information on ethnicity and race was either suppressed by the state supplying the data or missing in 21% of the cohort, admission type was missing for 9.4%.

† Wilcoxon rank sum

** x2


Table (E) T-3 CEA-CABG Rate Over Time*

CEA / CABG / CEA-CABG / Proportion of all CABG where CEA-CABG are combined
1993 / 12,625 / 43,272 / 481 / 1.10%
1994 / 15,783 / 47,908 / 567 / 1.17%
1995 / 21,220 / 51,539 / 695 / 1.33%
1996 / 28,266 / 72,200 / 1084 / 1.48%
1997 / 30,796 / 80,737 / 1338 / 1.63%
1998 / 14,009 / 34,444 / 593 / 1.69%
1999 / 13,770 / 34,073 / 614 / 1.77%
2000 / 7,113 / 19,069 / 293 / 1.51%
2001 / 28,166 / 71,130 / 1092 / 1.51%
2002 / 7,211 / 17,509 / 281 / 1.58%

* p < .0001 x2


Table (E) T-4 Co-Morbidities among the cohorts

CEA / CABG / CEA and CABG / p*
Condition (%)
Acute myocardial infarction
(as admitting diagnosis) / 0.8% / 7.1% / 7.3% / < .0001
Congestive heart failure / 5.4% / 16.9% / 21.7% / < .0001
Prior CVA / 4.4% / 1.1% / 3.0% / < .0001
COPD / 14.1% / 13.6% / 21.0% / < .0001
Diabetes mellitus / 23.4% / 27.2% / 31.1% / < .0001
Charlson index / < .0001
0 / 55.1% / 46.5% / 36.7%
1 / 29.4% / 32.4% / 34.7%
2 / 8.5% / 11.4% / 15.3%
3 / 4.9% / 6.1% / 8.5%
4 / 2.1% / 3.6% / 5.0%

* x2


Table (E) T-5 Logistic Regression Model of Disease States for Combined Outcomes of Death or Postoperative Stroke

Effect / Comparison / slope estimate / Odds Ratio / 95% CI / p
CEA-CABG / CABG / 0.5013 / 1.85 / 1.69 – 2.03 / <.0001
Age > 65 / Age < 65 / 0.2166 / 1.54 / 1.49 – 1.60 / < .0001
Female / Male / - 0.0884 / 0.84 / 0.82 – 0.86 / < .0001
Urban, teaching hospital / rural / 0.0418 / 1.06 / 0.99 1.13 / .0015
Urban, non-teaching hospital / rural / -0.0278 / 0.99 / 0.92 1.06 / .034
Prior stroke / none / 0.6577 / 3.73 / 3.60 3.82 / < .0001
Severe heart disease / none / 0.0788 / 1.17 / 1.11 – 1.23 / <.0001
Pulmonary disease / none / 0.0069 / 2.06 / 2.00 – 2.11 / < .0001
Renal failure / none / 0.0097 / 5.13 / 4.94 5.33 / < .0001