Name: ______Date: ______Hour: ______
BIOLOGY B.2016
On-line DNA Interactive Worksheet
In this activity, you will have an opportunity to review the concepts of DNA structure, DNA replication, DNA transcription and translation. Follow the directions below, and answer the questions at the end of this sheet.
Procedure:
1. With a partner, log on to a computer and go to the following website: www.dnai.org/index.htm Be certain that the audio is on.
2. Click on the word ‘Code’ from the bar near the top of the page.
3. From the Code page, click on ‘finding the structure’ from the bar at the bottom of the page.
4. Now, choose ‘problem’ from the task bar at the top, and read about the discovery of nuclein.
5. When you are finished, click ‘players’ on the task bar. Click on individual frames from the filmstrip to read about the people involved in discovering the structure of DNA.
6. Now, click on ‘pieces of the puzzle’. As you move your cursor over the pieces of the puzzle, you can find out what each puzzle piece describes. Choose one or two and review the material there. Be sure to take a look at Rosalind Franklin’s X-ray crystallography image.
7. Now, click on ‘putting it all together’. From this page, first look at ‘the DNA double helix’, then click on ‘base pairing interactive’ and try the activity!
8. Now, click on ‘copying the code’. You can go directly to ‘putting it all together’. (you may look at the other parts of this site at home).
9. Click on ‘Replication’ and choose ‘large viewing option’. Right click on the image, then ‘zoom in’ to make the image larger. Try to identify leading and lagging strands in this movie. Be sure that your speakers are on so that you can hear the narration.
10. Next, click on the ‘interactive’ and build your own RNA strand.
11. Finally, click on ‘transcription’ and follow the directions for the replication movie to view this feature.
12. Now, click on ‘reading the code’. Choose the ‘putting it together’ first, then click on ‘translation’ and view the movie. Finally, click on ‘interactive’ and build a protein.
13. Finally, log out and answer the analysis questions on the reverse of this direction sheet. These analysis questions will be due the next time class meets.
Analysis Questions:
1. Who first isolated what would later turn out to be DNA? ______
2. Which scientist believed that the structure of DNA was a triple helix? ______
3. What did Rosalind Franklin determine from her X-ray of crystals of DNA? ______
4. The process of DNA replication makes ______from ______.
5. The process of DNA transcription makes ______from ______.
6. The process of translation makes ______from ______.
7. The codon is found on molecules of ______and consists of three ______.
8. The anti-codon is found on molecules of ______and consists of three ______.
9. The job of mRNA is to: ______
10. The job of tRNA is to: ______
11. Amino acids are joined by ______bonds, which are a type of ______bond, and then produce molecules called ______.
12. Ribosomes consist of two materials, ______and ______.
13. A ribosome has ______subunits, and the ______is sandwiched in between during translation.
14. There are ______hydrogen bonds between cytosine and guanine, and ______hydrogen bonds between adenine and uracil.
15. As each new DNA strand made during the process of DNA replication contains one original and one new strand, DNA replication is said to be ______.