OhioMiamiValley Chapter, Society for Neuroscience

Neuroscience Day – May 16, 2008

WrightStateUniversity

Program

10:00 – 10:45 a.m.
Lobby – White Hall /
Registration & Poster Set-up
10:45 – 11:00 a.m. /
Introductory Comments
Tim Cope, Ph.D., 2008 President OMV-SfN
11:00 a.m. – 12:15 p.m.
Gandhi Auditorium
101 White Hall /
Distinguished Speaker
Barry Connors, Ph.D., Professor and Chair of Neuroscience, BrownUniversity
Title: Eclectic Electric Synapses in the Brain
12:30 – 1:30 p.m.
Tent on lawn between White Hall and the Student Union /
Lunch
1:30 – 3:00 p.m.
Gandhi Auditorium
101 White Hall / Student Presentations
Soumya Banerjee (MiamiUniversity)
Remodeling the Drosophila Abdominal Motor System during Metamorphosis
Martine Lamy (University of Cincinnati)
Alterations in fMRI Brain Activation are Associated with Biochemical Abnormalities in Bipolar Disorder
Katrina Paumier (University of Cincinnati)
Antidepressant-mediated Neuroprotection of the Nigrostriatal Pathway in a Rodent Model of Parkinson's Disease
Adam Deardorff (WrightStateUniversity)
Calcium Binding Proteins in The Medial Nucleus of the Trapezoid Body of Normal and Deaf (dn/dn) Mice
Ian Wenker (WrightStateUniversity)
The Role of Purnergic Signaling in the Activation of the Volume-Regulated Anion Channel in 1321N1 Astrocytoma Cells
3:00 – 5:30 p.m.
White Hall Lobby / Poster Session and Reception
5:15 p.m.
White Hall Lobby / Poster Competition Awards

OhioMiamiValley Chapter, Society for Neuroscience

Neuroscience Day – May 16, 2008

WrightStateUniversity

Poster Presentations

Poster1

Presenter: AnneChristiansen,Psychiatry,University of Cincinnati

Coauthors: Y.M. Ulrich-Lai, J.P. Herman

Title: Stress and sucrose modulation of pro-opioid mRNA expression in neural pathways mediating stress and reward

Key words:

Poster2

Presenter: ShwetaNayar,Zoology,MiamiUniversity

Coauthors: Dr.Phyllis Callahan, Dr.Emily Murphree, Dr. James Janik

Title: Role of Orphanin FQ/Nociceptin in the neuroendocrine response to stress in postpartum female mice

Key words: Stress,Opiates

Poster3

Presenter: NicoleNichols, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: Katie A. Wilkinson, Frank L. Powell, Robert W. Putnam

Title: Chronic Hypoxia (CHx) Suppresses the Chemosensitive Response of Individual Nucleus Tractus Solitarius (NTS) Neurons from Adult Rats

Key words:

Poster4

Presenter: NathanEvanson,Neuroscience Graduate Program,University of Cincinnati

Coauthors: Y.M. Ulrich-LaiA.R. FurayJ.G. TaskerJ.P. Herman

Title: Hypothalamic paraventricular cannabinoid receptor signaling in fast feedback inhibition of the hypothalamus-pituitary-adrenal axis response to acute restraint stress

Key words: HPA axis, rats, cannabinoid, CB1, glucocorticoid

Poster5

Presenter: JamesOlson,Emergency Medicine,WrightStateUniversity

Coauthors: Leasure, James E.

Title: ATP-mediated cell volume regulation during oxidative stress.

Key words: hippocampus

Poster6

Presenter: JonathanFlak,Psychiatry,University of Cincinnati

Coauthors: M. M. OSTRANDER, N. K. MUELLER, J. P.HERMAN

Title: Chronic stress-induced neurotransmitter plasticity in the hypothalamic paraventricular nucleus

Key words: HPA axis, CRH, synaptophysin, glutamate, norepinephrine, GABA

Poster7

Presenter: Meera Seshadri,Zoology,MiamiUniversity

Coauthors: Dr.Phyllis Callahan, Dr.Emily Murphree, Dr. James Janik

Title: Gender differences in and the effects of OFQ/N on the Prolactin-receptor expression in the rat choroid plexus following stress

Key words: Stress, Prolactin, Opiates

Poster8

Presenter: AnnHemmerle,Neuroscience Graduate Program/Neurology,University of Cincinnati

Coauthors: J.W. Dickerson, K.H. Lundgren, B.A. Packard, K.R. Jones, J.P. Herman, K.B. Seroogy

Title: Chronic variable stress alters neurotrophic factor and neurotransmitter synthesizing enzyme expression within the mesotelencephalic system of adult rats

Key words: depression, animal model, gene expression, neurotrophic factor, stress

Poster9

Presenter: CrystalStuckey,Emergency Medicine,WrightStateUniversity

Coauthors: Olson, James E.; and D'Agostino, Dominic P.

Title: Hypoosmotic swelling of rat C6 glioma cells causes cell death via oxidative stress.

Key words:

Poster10

Presenter: EricKrause,Psychiatry,University of Cincinnati

Coauthors: Susan J. Melhorn, Jon F. Davis, Karen A. Scott, Li Y. Ma, Annette D. de Kloet, Stephen C. Benoit, Stephen C. Woods, and Randall R. Sakai.

Title: AT1 receptors in the subfornical organ mediate the drinking and hypothalamic-pituitary-adrenal response to systemic isoproterenol.

Key words: angiotensin II, corticosterone, ACTH, water intake, hypotension, hypovolemia, HPA

Poster11

Presenter: Brian Tucker, Neuroscience, Cell Biology and Physiology,WrightStateUniversity

Coauthors: James Olson, PhD

Title: The Role of Glutamate in Taurine Efflux during Oxidative Stress

Key words: Glutamate, Taurine, Oxidative Stress

Poster12

Presenter: JenniferMcGuire,Psychiatry,University of Cincinnati

Coauthors: James P. Herman, Floyd R. Sallee, Renu Sah

Title: Neuropeptide Y (NPY) and posttraumatic stress disorder (PTSD): Studies in a chronic variable stress model

Key words:

Poster13

Presenter: BrianMurphy,Anesthesia,University of Cincinnati/Cincinnati Children's MedicalCenter

Coauthors: Steve Danzer, Cynthia Walter, Raymund Pun

Title: Real-time imaging of dentate granule cells in organotypic hippocampal explant cultures made from Thy1-YFP-expressing mice

Key words: hippocampus, dentate gyrus, organotypic explant culture, lesioning, neuronal circuitry, transgenic mouse linesSTev

Poster14

Presenter: Soumya Banerjee,Zoology,MiamiUniversity

Coauthors: Meredith Dorr, Holly Rataiczak, Badrinath Krishan and Joyce Fernandes

Title: Nervous system remodeling in Drosophila: The fate of Hb9-positive neuron during metamorphosis

Key words: nervous system remodeling, Motor neuron,cell death

Poster15

Presenter: Lynn Hartzler,Neuroscience, Cell Biology & Physiology,WrightStateUniversity

Coauthors: Jay B. Dean, Robert W. Putnam

Title: Developmental changes in the chemosensitive response in locus coeruleus neurons from neonatal rats

Key words:

Poster16

Presenter: RobertHufnagel,Neuroscience,University of Cincinnati

Coauthors: Quinn M, Brown NL

Title: Evaluating the competence of the earliest retinal progenitors to precociously adopt late fates

Key words: Retinal neurogenesis, bHLH transcription factors, Math5, Math1

Poster 17

Presenter: Christian Gutierrez,Zoology,MiamiUniversity

Coauthors: Alexander BerrebiKatia Del Rio-Tsonis

Title: Regulators of Retina Pigmented Epithelial(RPE) Cell Transdifferentiation

Key words: Transdifferentiation, Retina Regeneration

Poster18

Presenter: Valerie Siembab,Neuroscience, Cell Biology & Physiology,WrightStateUniversity

Coauthors: C. A. Smith, N. A. Shneider, M. C. Berrocal, F. J. Alvarez

Title: Alterations in Ia afferent input strength modulates the maturation of synaptic excitatory input organization on Renshaw cells

Key words: Renshaw Cell, Recurrent Collaterals, VGLUT1, VAChT

Poster19

Presenter: Meghana Tare,Biology, University of Dayton

Coauthors: Madhuri Kango Singh Amit Singh

Title: Opposing interactions between homothorax and Notch pathway genes Lobe and Serrate define ventral eye margin of the developing eye field

Key words: Eye Development,Drosophila melanogaster, Axial Patterning, Growth, Homothorax, Lobe

Poster20

Presenter: Courtney Smith, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: Shneider N.A., Berrocal M.C., Alvarez F.J.

Title: Influence of sensory afferents and motoneurons on the developmental regulation of calbindin and parvalbumin expression in spinal interneurons.

Key words:

Poster21

Presenter: JieZhu, Zoology, MiamiUniversity

Coauthors: Tracy Hynes, KatiaDelRio Tsonis

Title: Canonical Wnt Signaling Regulates Chick Retina Regeneration

Key words: Wnt, chick, retina, regeneration

Poster22

Presenter: SarahOros,Biology, University of Dayton

Coauthors: Monica Berkemeier, Dr. Amit Singh, Ph.D.

Title: Drosophila model to study genetic basis of birth defect in eye

Key words:

Poster23

Presenter: MindyCall,Ophthalmology, University of Cincinnati

Coauthors: CY Kuan, Cincinnati Children's Medical CenterWW Kao, University of Cincinnati

Title: Development of a Mouse Model to Characterize and Ablate Pyramidal Neurons in the Hippocampus

Key words: bi-transgenic mouse model, hippocampus

Poster24

Presenter: TeresaGarrett, Pharmacology & Toxicology, WrightStateUniversity

Coauthors: C.M. Rapp, A.R. Kessler, & J.B Lucot

Title: The effects of CBDP and sarin on fear-potentiated startle and y-maze performance in mice.

Key words: fear potentiated startle, y-maze, sarin, behavior training, mice, locomotor activity

Poster25

Presenter: Martine Lamy, Neuroscience, University of Cincinnati

Coauthors: Lamy, M; Cerullo, MC;Mills, NP; Allendorfer JB; Eliassen, JC; Adler, CM; Strakowski, SM; DelBello MP

Title: Alterations of face-responsive visual regions in adolescent bipolar disorder during emotional face processing.

Key words: bipolar disorder, ADHD, adolescence, fMRI, emotion,

Poster26

Presenter: JamesLucot, Pharmacology & Toxicology, WrightStateUniversity

Coauthors: James B. Lucot, Shenika Poindexter, Steven Baird, M. Mach

Title: Low dose sarin suppresses dopamine function in selected brain regions: relevance to fear potentiation of startle.

Key words: sarin,FPS,dopamine

Poster27

Presenter: JonathanDickerson, Neurology, University of Cincinnati

Coauthors: A.M. Hemmerle, K.H. Lundgren, and K.B. Seroogy.

Title: Supranigral infusion of neuregulins improves behavioral recovery in a partial-lesion model of Parkinson’s disease.

Key words: neuregulin, Parkinson's Disease, 6-hydroxydopamine, motor function, substantia nigra, stereology.

Poster28

Presenter: ChristineRapp, Pharmacology & Toxicology, WrightStateUniversity

Coauthors: T. L. Garrett, K. E. Irwin, R. D. Grubbs, J. B. Lucot

Title: Neuronal damage in mice over time after injecton with CBDP and sarin.

Key words: sarin, CBDP, immunohistochemistry, neuronal cell death

Poster29

Presenter: RyanWalker, Zoology, MiamiUniversity

Coauthors: A. Foster, C.L. Randolph, and L.G.Isaacson

Title: Changes in NGF and NT-3 protein species in the superior cervical ganglion following axotomy or crush injury of postganglionic axons

Key words: neurotrophin transport, retrograde, proNGF

Poster30

Presenter: MatthewLoftspring, Neurology, University of Cincinnati

Coauthors: Matthew C. Loftspring, Jeremiah McDole, Aigang Lu, Aaron J. Johnson, Joseph F. Clark

Title: Intracerebral hemorrhage leads to infiltration of several leukocyte populations with concomitant pathophysiological changes.

Key words: stroke, intracerebral hemorrhage, inflammation, leukocyte infiltration

Poster31

Presenter: JeremiahMcDole, Neurology, University of Cincinnati

Coauthors: Istvan Pirko, Jeremiah McDole, Yi Chen, Scott Dunn, Diana M. Lindquist, Aaron Johnson

Title: Prospective MRI Study of Brain Atrophy and Its Relationship to Disability in a Murine Model of MS

Key words: MRI, MRS, TMEV, MS,

Poster32

Presenter: JenniferO'Malley, Neuroscience, University of Cincinnati

Coauthors: N. D. Levine, C. E. Sortwell, T. J. Collier, T. Schallert, K. Steece-Collier;

Title: Therapeutic Implications of Dendritic Spine Loss in a Rat Model of Parkinson’s disease.

Key words: parkinson's disease, dendritic spines, MSN, nimodipine, dyskinesias, levodopa

Poster33

Presenter: KatrinaPaumier, Neurology, University of Cincinnati

Coauthors: Sortwell CE, Daley BF, Terpstra BT, Madhavan LM, Levine ND, and Collier TJ.

Title: Chronic antidepressant treatment is neuroprotective in a rat model of Parkinson's disease

Key words: Parkinson's disease, neuroprotection, antidepressants

Poster34

Presenter: AnneSpieles-Engemann, Neurology, University of Cincinnati

Coauthors: Michael M. Behbehani, Brian T. Terpstra, Timothy J. Collier, Kathy Steece-Collier, Lalitha Madhavan, Katrina Paumier, Susan L. Wohlgenant, Sara Gombash, and Caryl E. Sortwell

Title: Establishment of a Clinically Relevant Model of Long-Term STN Deep Brain Stimulation in Parkinsonian Rats

Key words: Deep brain stimulation, Parkinson's disease, Subthalamic nucleus

Poster35

Presenter: BrianTerpstra, Neurology, University of Cincinnati

Coauthors: J.W. Lipton, K.L. Paumier, N.D. Levine, S.L Wohlgenant, A.Y. Yu and C.E. Sortwell

Title: Inosine Protects Mesencephalic Dopamine Neurons from Parkinsonian Insult in vitro and Accumulates in the Nigrostriatal Pathway Following Peripheral Administration

Key words: Parkinson's Disease, Inosine, Neuroprotection

Poster 36

Presenter: Jane Allendorfer, Neuroscience/Psychiatry, University of Cincinnati

Coauthors: Lamy M, Eliassen JC

Title: Human recreational MDMA use affects fMRI brain activation during working memory

Key words: fmri, memory, mdma

Poster37

Presenter: MelissaBautista, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: B. Walmsley, R. E. W. Fyffe

Title: Ultrastructural analysis of endbulbs and calyces of Held in the AVCN and MNTB in normal andcongenitally deaf mice

Key words:

Poster38

Presenter: LorenHoffmann, Psychology, MiamiUniversity, Oxford

Coauthors: Stephen D. Berry

Title: Hippocampal Modulation of Cerebellar Learning I: IPN

Key words:

Poster39

Presenter: Loren Hoffmann, Psychology, MiamiUniversity, Oxford

Coauthors: Stephen D. Berry

Title: Hippocampal Modulation of Cerebellar Learning II: Cortex

Key words:

Poster 40

Presenter: JeannineCrum, Neuroscience, Cell Biology, & Physiology, WrightStateUniversity

Coauthors: K. Bullinger, L. Goss, P. Nardelli, & T. Cope

Title: Neuregulin 1 implicated in injury induced synaptic plasticity.

Key words: synaptic plasticity, synaptic strengthening, nerve injury, axotomy, neuregulin, erbB

Poster41

Presenter: KatieBullinger, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: Cope, Timothy C

Title: Synaptic responses to high frequency activation of regenerated Ia afferents

Key words: Regeneration, Synapses, Spinal Cord, Motoneurons, Primary Afferents, Muscle Spindles, Reinnervation

Poster42

Presenter: AdamDeardorff, Neuroscience, Cell Biology, Physiology, WrightStateUniversity

Coauthors: R. Tracy, J. Roebel, B. Walmsley, R.E.W. Fyffe

Title: Calcium Binding Proteins in Brainstem Auditory Nuclei of Normal and Deaf (dn/dn) Mice

Key words: Auditory, Calcium

Poster43

Presenter: JimEliassen, Psychiatry, University of Cincinnati

Coauthors: Maria M. Martini, Jane B. Allendorfer, Martine Lamy

Title: Recreational MDMA use affects fMRI brain activation in serotonin target regions during associative learning

Key words: operant conditioning, instrumental learning, drug abuse, fMRI

Poster44

Presenter: ZhihuiDeng, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: S.H. Romer, T.C.Cope, L.Goss, P. Nardelli, K. Bullinger, R.E.W Fyffe

Title: Expression of small conductance Ca2+ -activated potassium (SK) channels in mammalian spinal motoneurons

Key words:

Poster45

Presenter: ParamaPaul, Zoology, MiamiUniversity

Coauthors: K. Ghosal, J.R. Allen, L. Wene, K.A. Killian

Title: Social Experience and Aggression in Male Crickets

Key words: aggression, insect, dominance, social behavior, invertebrate

Poster46

Presenter: RogerFecher, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors: K. Dominguez, S.H. Romer, R. Fecher, Z. Deng, P. Nardelli, L. Goss, T.C. Cope, R.E.W. Fyffe

Title: Redistribution of somatic membrane Kv2.1 ion channels on spinal motoneurons following peripheral nerve injury

Key words:

Poster47

Presenter: JudithStrong, Anesthesiology, University of Cincinnati

Coauthors: J.-G. Wang, J. A. Strong, W.-R. Xie, J.-M. Zhang

Title: Chronic GRO/KC Exposure Enhances Voltage-Gated Na Currents in Small Diameter Rat Sensory Neurons.

Key words: inflammation, pain, cytokine, sodium current

Poster48

Presenter: PatrickSonner, Neuroscience, Cell Biology, and Physiology, WrightStateUniversity

Coauthors: Jessica Filosa, Javier Stern

Title: Intracellular Ca2+ dynamics in presympathetic PVN neurons during repetitive firing.

Key words: intracellular calcium, presympathetic, PVN

Poster49

Presenter: GeorgetteSuidan, Neurology, University of Cincinnati

Coauthors: Jon Dickerson, Kim Seroogy, Istvan Pirko, Aaron J Johnson

Title: Rapid induction of VEGF by CD8 T cells precedes CNS vascular permeability

Key words: VEGF, CD8 T cells, Blood Brain Barrier, tight junctions

Poster50

Presenter: MelGoldfinger, Neuroscience, Cell Biology & Physiology, WrightStateUniversity

Coauthors:

Title: Markov NaCh Kinetics Shape the Form of Axonal Relative Refractoriness

Key words: sodium channel, Markov kinetics, computational neuroscience, relative refractoriness, supernormality

Poster51

Presenter: Guangze Li,Emergency medicine,WrightStateUniversity

Coauthors: James E. Olson

Title: Mechanisms of Hypoosmotic Sensitization of ATP-activated Anion Conductance in Cultured Hippocampal Astrocytes

Key words: Astrocytes, ATP, Patch Clamp, Purinergic receptor

Poster52

Presenter: IanWenker, Neuroscience, Cell Biology and Physiology, WrightStateUniversity

Coauthors: James Olson PhD

Title: The Role of Purnergic Signaling in the Activation of the Volume-Regulated Anion Channel in 1321N1 Astrocytoma Cells

Key words: Astrocyte, electrophysiology, cell volume, purinergic signaling, VRAC

Poster53

Presenter: JamesOlson,Emergency Medicine,WrightStateUniversity

Coauthors: Dines, Megan; Caraman, Elena; Aston, Jill; Ballester, Mike; McCarthy, Mary.

Title: Early Brain Edema Predicts Poor Outcome In Head Trauma Patients.

Key words:

Poster54

Presenter: JamesOlson,Emergency Medicine,WrightStateUniversity

Coauthors:

Title: Promoting neuroscience education with Science Olympiad™

Key words: