Nomination Form

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For Office Use

The Nomination for the ……..………………………………….…………… has been received along with all the enclosures on ……………………

Signature

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Nomination for Special Awards

We, the members of Association of Biotechnology and Pharmacy, would like to nominate the following person as a candidate for the award of

Life time Achievement Award in Biotechnology

Life time Achievement Award in Pharmacy

Talented IndustrialBiotechnologist Award

ABAP-Senior Scientist Award

(Tick which ever is applicable)

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Name of the Nominee:…Dr.K.S.NAGESH …

Address K.S. Nagesh, Door No. 524, 4 /3 Main,E and F Block, Ramkrishnanagar

Mysore-570022, Karnataka, India

Phone…8050944624………Fax………….. Email

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We certify the statement made by the candidate and in our opinion he/she is fully qualified for the above award

Proposer Name ……………………………………Signature………..………………...

Supporter Name……………………………………Signature………………..…..……

A Fellow/Life Member can nominate two members for each award every year

BIGRAPHICAL INFORMATION OF NOMINEE

1. Name in full: Dr.K.S.NAGESH

2. Date of Birth & Age: 23/06/1972 and 43 years

(on the day of application)

3. Nationality: Indian

4. Present Position/Designation: Lecturer

5. Field of Specialization: Medicinal plant Tissue culture and Biodiversity

Conservation

6. Address:

Official: GovernmentCollege,

Basavapattana, Arakalgud Taluk

Hassan District, Karnataka

Residence: Dr. K.S. Nagesh

Door No. 524, 4 /3 Main,

E and F Block

Ramkrishnanagar

Mysore-570022

Karnataka, India

Phone: 8050944624 Fax: Email:

7. Academic Details:

(Degree, Post-graduation, PhD, DSc and other research qualifications)

Degree / Name of University / Subject(s) / Year of Passing
B.Sc., / J.S.S. College,
University of Mysore / Chemistry
Botany
Zoology / 1993
M.Sc., / Department of Botany
University of Mysore / Botany / 1995
Ph.D. / University of Mysore / Botany / 2004
KSLET- for Assistant Professorship Cleared on 2014 (Accredited by UGC)
Title of Thesis: "In vivo, invitro and Bioactivity studies of traditional
and economically important medicinal plants"

Research Experience:

Designation / Institution / Area of Research / Duration
Technical Assistant / Department of Botany,University of Mysore
Central Silk Board Sponsored Project / Mulberry mutation breed through tissue culture method" / 1996-1997
Junior and Senior Research Fellowship / Department of Botany,University of Mysore
Manasagangotri,Mysore-570006 / "In vivo, invitro and Bioactivity studies of traditional and economically important medicinal plants" / 1998-2002
CSIR- Research Associate / Department of Botany,
Sri Krishnadevaraya UinversityAnantapur, Andhra Pradesh / Survey, Conservation and Utilization of Bryophytes of Andhra Pradesh Undertaken by Prof. T. Pullaiah / 2008 - 2010

8. Academic Distinctions like Gold Medals/Endowment/Memorial Lectures Delivered:

9. Honors and Awards:

  1. Nagesh and Shanthamma C. 2001. Micropropagation of Curculigo orchioides Gaertn. An endangered anticancer Herb. National Conference on plant biotechnology helad at Warangal. Baggaed Best presentation Award.
  1. Nagesh K.S. 2002 In vitro Propagation and antioxidant activity of Curculigo orchioides Gaertn. Selected and presented for Young Scientist Award Under Indian Science Congress Association held at Lucknow.
  2. Nagesh K.S 2008. In vitro propagation and antioxidant activity of Curculigo orchioides Gaertn.Selected for Young Botanist Award under IBS held at Allahabad.

10.Teaching experience (years) :12 years

11.Research experience (years) : 6 years

12.No. of Ph.D(s) and MPhil(s) guided : Nil

13.No. of Books/Monographs Written/Edited: : 02

Books Published

  1. Sandhy Rani S., M. Sowghandhika, K.S. Nagesh, B. Shusheela, and T. Pullaiah. 2014. Bryophytes in Andhra Pradesh.ISBN978-81-211-0867- 6.Bishen Singh Mahendra Pal Singh. Dehra Dun (India).

14. Membership in Scientific Associations:

International Journal of Advanced Research in Biological Sciences / Editorial Board as Reviewer
Indian Botanical Society / Life member
Indian science congress / Annual membership
Bangalore Nano, Karnataka Science And Technology / Annual Membership

15. Publications and Patents: Attached in separate sheets

(Attach List of Publications and Patents with names of authors, impact factors and

attach best 5 papers reprints and proof of filing patents, Attach separate sheets)

PUBLICATIONS: / Published (15) / Accepted/ in Press
National / International / National / International
Research papers: / 06 / 09
Books: / 01 / -
Book chapters in edited book / 04 / -

15. Fellows to the National Academies: Nil

16. Achievements and Discoveries:Enclosing in separate sheets

17. A Critical Analysis of Highlighting the Discoveries of the Nominee not Exceeding
150 words (if necessary, attach separate sheets):Enclosing in separate sheets

18.Innovative Contributions of the Nominee to the Society (not exceeding 150 words)

Enclosing in separate sheets

Annexure-I

Published/Accepted papers

  1. Jagadish Chandra and Nagesh K.S. 1997. Micropropagation through nodal bud culture in mulberry (Morus indica) Cv. S-13. Journal of Swamy Botanical Club. 14; 102-105. ISSN 0256 - 9493
  2. Nagesh K.S. 2008. High frequency of multiple shoot induction of Curculigo orchioides Gaertn. Shoot tip V/S Rhizome Disc Taiwania- international. Journal of life science. 53(3):242-247. ISSN 0372-333X
  3. Nagesh K.S., Harish Nayaka., Shylaja M. Dharmesh., Shanthamma C. and Pullaih T. 2008 In vitro Propagation and Antioxidant activity of Curculigo orchioides Gaertn. Journal of Tropical Medicinal plants. 9(2): 404-410. ISSN: 1511-8525
  4. Nagesh K.S. and C. Shanthamma. 2009. Antimicrobial activity of Curculigo orchioides rhizome extract on pathogenic bacteria. African Journal of Microbial Research 3(1): 05-09. (Impact factor 0.3).ISSN: 1996-0808
  5. Nagesh K.S., Bhgyalakashmi, N and Shanthamma C. 2009. Role of Polarity in de novo shoot bud initation in Rhizome Disc of Curculigo orchioides Gaertn. and its encapsulation and storability in Acta Physiologia Plantarum 31:699-704.(Impact factor 1.2)ISSN: 0137-5881
  6. Nagesh K.S., C. Shanthamma and T. Pullaiah 2010.Somatic embryogenesis and plant regeneration in callus culture of Curculigo orchioides Gaertn. Indian journal of Biotechnology.9: 408-413. (Impact factor 0.4).ISSN 0972-5849
  7. Nagesh K.S. and C. Shanthamma 2011. Micropropagation and antioxidant activity of Mollugo nudicaulis Lam. Journal of Medicinal Plants Research Vol. 5(6), pp. 895-902, (Impact factor 0.5).ISSN: 19960875
  8. Nagesh K.S. and C. Shanthamma 2011. Wound healing acivity ofMollugo nudicaulis Lam -In vitro derived callus V/S Field grown leaves. Journal of Herbs, Spices and Medicinal Plants:17(3): 275-284. (Impact factor 0.8).ISSN1049-6475 (Print)
  9. Sandhy Rani S., M. Sowghandhika, B. Shusheela, K.S. Nagesh and T. Pullaiah. 2011. Addition to the bryophytes of Southern peninsular India. J. Indian Bot. Soc. 90(1&2)75-79. ISSN: 0019-4468.
  10. Prakasha., RaveeshaK.A., Rajashekar N., Nagesh K. S., 2012. Anthelmintic activity of Tinospora sinensis miers.(Stem and Callus Extract) International Journal of Pharmaceutical Research & Development 4(05): 024 – 028.ISSN 0974-9446
  11. Vinay B. Raghavendra, Lokesh S., Nagesh K. S., Chandra Nayak, Niranjana S., Ramachandrappa. 2013. Induction of systemic resistance by biocontrol agents against bacterial blight of cotton caused by Xanthomonas campestris pv. Malvacearum J. Plant Pathol. 02 : 59-69.ISSN:2306-1650
  12. Sowghandhika M., Nagesh K.S., Sandhy Rani S., Shusheela, B. and Pullaiah T. 2013. Hepaticae and Anthocerotae in Vishakapatnam district of Andhra Pradesh, India. Indian J. of Forestry. 36 (2) ; 261-265. ISSN 0971-9431
  13. Vinay Basavegowda Raghavendra, Nagesh Kallahally Sugnanachar, Govindappa M., Lokesh Siddalingaiah. (2016). First report of leaf spot Caused by Cercospora apii Fresen of Tabebuia argentea in India. Int. J. Adv. Res. Biol. Sci. 3(7): 203-205.ISSN 2348-8069
  14. Nagesh K.S. and C. Shanthamma 2016.An overview on tissue culture studies ofCurculigo orchioidesGaertn: An endangered multi-potential medicinal herb. Journal of Medicinal Plants Studies :4(3): 119-123 (ISSN:2394 - 0530
  15. Nagesh K.S. and C. Shanthamma 2016. Encapsulation of somatic embryoids of Curculigo orchioides Gaertn. and its germination. European Journal of Biotechnology and Bioscience:4(6): 38-42.

Books Published

  1. Sandhy Rani S., M. Sowghandhika, K.S. Nagesh, B. Shusheela, and T. Pullaiah. 2014. Bryophytes in Andhra Pradesh. ISBN 978-81-211-0867- 6.Bishen Singh Mahendra Pal Singh. Dehra Dun (India).

Invited Book chapters Published

  1. Nagesh K.S. and Shanthamma 2011. Studies on de novo shoot bud regeneration, organogenesis and somatic embryogenesis in Curculigo orchioides Gaertn.: An endangered medicinal herb. In :Plant Tissue culture : Emerging Trends. T. Pullaiah (Eds).Regency Publications New Delhi : 90-102.( ISBN 81-89233-69-6, ISBN 978-81-89233-69-3)
  2. Ramesh C., Lakshmi, H., Sugunna Kumari, S.,Pushpalatha C., Nagesh K.S., and Suresh Kumar C. 2011. Biotechnological Prospective of Mulberry and Silk worms. In: Application of Biotechnology in Sericulture. Venkatesh Kumar R. and Shyam Kumar V.(Eds). Studium Press (India) Pvt. Ltd. New Delhi : 43-70.( ISBN 978-93-80012-48-3)
  3. Nagesh K.S. 2012. Herbal antioxidants and antioxidant assays In: Encyclopedia of Herbal Antioxidants (Volumes1-3) T.Pullaiah (Ed).Regency Publications New Delhi.:1-36.(ISBN 978-81-89233-69-3)
  4. Nagesh K.S. 2012. Antioxidant assays In: Encyclopedia of Herbal Antioxidants (Volumes1-3) T.Pullaiah (Ed).Regency Publications New Delhi.:1-36.(ISBN 978-81-89233-69-3,70-9,71-6,72-3)

Annexure-II

A Critical Analysis of Highlighting the Discoveries of the Nominee

IN VIVO, IN VITRO AND BIOACTIVITY STUDIES OF TRADITIONAL AND ECONOMICALLY IMPORTANT MEDICINAL PLANTS

Despite the increasing use of medicinal plants, their future, seemingly, is being threatened by complacency concerning their conservation. Reserves of herbs and stocks of medicinal plants in developing countries are diminishing and in danger of extinction as a result of growing trade demands for cheaper healthcare products and new plant-based therapeutic markets in preference to more expensive target-specific drugs and biopharmaceuticals.

To cope up with this alarming situation, the Plant biotechnology played important role in the mass multiplication and provide source for extraction of secondary metabolites.

Therefore, the major objectives of the my research programme is to select important medicinal plants for in vitro propagation, extraction and evaluation of antioxidant activity,wound healing and hepatoprotective activity and antibacterial properties.

In the present investigation two medicinal plant spices such as Mollugo nudicaulis Lam - a traditionally important medicinal plant and Curculigo orchioides Gaertn.- an endangered multipotential medicinal plant have been selected.

M. nudicaulis (Molluginaceae) is a traditionally important wild medicinal herb. The leaves are used by Indian traditional practitioners for curing several disorders including whooping cough, jaundice and as antiseptic Although it is distributed in different geographical locations, collection of the plant material for extraction of drugs is a major task as this small herb grows only in localized areas during rainy season.

Curculigo orchioides Gaertn. (Hypoxidaceae) is a valuable wild, endangered medicinal plant Indiscriminate and over exploitation also pushed this plant to the present threatened and endangered status.

The PhD work emphasis on the following aspects

  1. In vitro studies of Mollugo nudiculis Lam.
  2. In vitro studies of Curculigo orchioides Gaertn.
  3. Comparative bioactivity studies using native (in vivo ) plant parts and in vitro derived callus extracts for
  4. Antioxidant activity using in vitro assays
  5. Hepatoprotective activity using animal models
  6. Wound healing Activity using animal models
  7. Antibacterial activity using pathogenic bacteria.

Innovative Contributions of the Nominee to the Society

Herbal drugs have been extracted from plant cultivated in fields or from their natural habitats. It has been reported that nearly 85% of plants used traditionally as ingredients in crude drugs are collected from natural habitats (22). Endemicity, restricted distribution, small population, availability in particular season have caused a decline in wild population. To overcome these, in vitro cultures could be used as alternative method. From our results, it can be suggested that in vitro derived callus of M. nudicaulis and Curculigo orchioidescould be used as alternative to field grown plant for extraction of secondary metabolites throughout season. And also this biotechnological approaches help for conservation of the medicinal plants

The in vitro derived calli have shown a remarkable for

  1. Antioxidant activity using in vitro assays
  2. Hepatoprotective activity using animal models
  3. Wound healing Activity using animal models
  4. Antibacterial activity using pathogenic bacteria

and therefore hold promise for treating various ailment in humans after careful clinical evaluation studies

The demand for herbal remedies has been increasing significantly. Constant demands for some of the medicinal plants have affected their availability to a large extent for extraction of secondary metabolites.

The present findings are important and have implications in modern biotechnology, which can offer highly active antioxidants and antibacterial compounds for which there is great demand throughout the season. The protocol developed in the present investigation may serve as a basic tool for further exploitation of these two medicinal plants for further pharmacological applications and conservation for future needs.