Name______Date______

DNA & Protein Synthesis Test

Multiple Choice: Choose the BEST Answer.

_____1. Where does Translation occur?

A.  Nucleus

B.  Cytoplasm

C.  Chloroplast

D.  Phospholipid Bilayer

_____2. What amino acid does the codon AAC code for?

A.  Methionine

B.  Isoleucine

C.  Asparagine

D.  Glutamine

_____3. Which molecules make up the backbone of DNA?

A.  Ribose and Phosphate

B.  Deoxyribose and Sulfur

C.  Deoxyribose and Phosphate

D.  Ribose and Nitrogen

_____4. What is the name of the process that creates an exact copy of DNA so that all our cells can have the same genetic material?

A.  Transcription

B.  Replication

C.  Translation

D.  Meiosis

_____5. Which of the following is a Purine?

A.  Adenine

B.  Cytosine

C.  Thymine

D.  Uracil

_____6. How many hydrogen bonds hold together cytosine and guanine?

A.1

B. 2

C. 3

D. 4

_____7. Which molecules are involved in Transcription?

A.  DNA, mRNA, Proteins

B.  DNA, mRNA

C.  tRNA, Proteins

D.  tRNA, DNA

_____8. The genetic code in DNA depends on the order of

A.  Nuleotides

B.  Pyrimidines

C.  Phosphate Groups

D.  Sugar molecules

_____9. Who used X-ray Crystallography to discover the structure of DNA?

A.  Rosalind Franklin

B.  Watson and Crick

C.  Erwin Chargaff

D.  Oswald Avery

_____10. Sometimes mistakes in DNA replication are made. These are called…

A.  fragments

B.  mutations

C.  semi-conservative mistakes

D.  alternative base-pairing

_____11. Which of the following is NOT found in DNA?

A.  Thymine

B.  Uracil

C.  Phosphate

D.  Deoxyribose

_____12. How many codons are needed to specify 3 amino acids?

A.  3

B.  6

C.  9

D.  12

_____13. Using your codon chart, which of the following is NOT considered to be a STOP codon?

A.  UAG

B.  UAA

C.  UGA

D.  UUC

Matching: Match each item with the corresponding statement.

A. RNA B. DNA C. Both DNA and RNA D. Neither DNA or RNA

_____14. Nucleic Acid

_____15. Contains Ribose

_____16. Contains the base Thymine

_____17. Made up of amino acids

_____18. Made of nucleotides

_____19. single stranded with an indefinite shape

True/False: Decide whether or not the statement is completely true, or false.

_____20. Amino acids are held together by peptide bonds.

_____21. Erwin Chargaff said that adenine pairs with guanine and cytosine pairs with thymine.

_____22. The 3 types of RNA are messenger RNA, carrier RNA, and transfer RNA.

_____23. Transfer RNA brings amino acids to the ribosome during protein synthesis.

_____24. mRNA is produced during translation.

_____25. During transcription, we only transcribe a small piece of DNA called a gene.

_____26. The correct sequence in creating a protein is DNAàRNAàProtein.

Multiple Choice: Choose the BEST answer.

_____27. The anticodons for the mRNA sequence CUCAAGUGUUC are…

A.  GAG-UUC-ACG-AAG

B.  GAG-TTC-ACG-AAG

C.  CUC-GAA-CGU-CUU

D.  CUU-CGU-GAA-CUC

_____28. Which of the following would be the DNA sequence that made the mRNA sequence CUCAAGUGCUUC?

A.  CUCAAGUGCUUC

B.  GAGUUCACGAAG

C.  GAGTTCACGAAG

D.  AGACCTGTAGGA

_____29. Where does transcription occur?

A.  Nucleus

B.  Cytoplasm

C.  Ribosome

D.  Mitochondria

_____30. If a mutation occurs where ONE amino acid is changed and it changes to a STOP codon, what type of mutation has occurred?

A.  Frameshift mutation

B.  Missense substitution mutation

C.  Nonsense substitution mutation

D.  Insertion mutation

_____31. ANYTHING that causes a mutation is called a

A.  Mutagen

B.  Carcinogen

C.  Malfunction

D.  Ineffective Regulator

Matching: Determine which mutation has occurred from the original sequence below.

ORIGINAL DNA SEQUENCE: CTACCTGGACTCGAACCTGACT

_____32. CTACCTCGACTCGAACCTGACT
_____33. CTACCCTGGACTCGAACCTGACT
_____34. CACCTGGACTCGAACCTGACT
_____35. CTACCTGGACTCGAACCTGACT
_____36. CTACCTGGACTCGAACCTGAGT / A.  Insertion
B.  Substitution
C.  Deletion
D.  No mutation has occured

Short Answer:

37.

A) Transcribe the following sequence (remember to start and stop in the right spots!)

DNA: GACTACACACCCTTGGTCTATUAACGATGT

mRNA: ______

B) Translate the mRNA

______

38. Transcribe the following sequence.

DNA: GATTACACACCCTTGGTCTATUAACGATGT

mRNA: ______

B) Translate the mRNA

______

C) What type of mutation has occurred? ______

D) How will this effect the protein?

______

______