SUPPLEMENTARY TABLE: O’Hara, Lim, Mazzatti and Trayhurn. Complete List of Genes Whose Expression Is Differentially Regulated in Human (SGBS) Adipocytes by Macrophage-conditioned Medium at 24 h
Mean ‘fold-changes’ are shown relative to adipocytes incubated with unconditioned medium (n=6)
Description / Genbank ID / Fold Changematrix metallopeptidase 1 (interstitial collagenase) (MMP1) / NM_002421 / 2408
matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3) / NM_002422 / 1417
matrix metallopeptidase 10 (stromelysin 2) (MMP10) / NM_002425 / 1264
colony stimulating factor 3 (granulocyte) (CSF3) / NM_000759 / 860
chemokine (C-X-C motif) ligand 5 (CXCL5) / NM_002994 / 662
chemokine (C-X-C motif) ligand 5 (CXCL5) / NM_002994 / 463
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9) / NM_004994 / 390
if20d02.x1 Melton Normalized Human Islet 4 N4-HIS 1 cDNA clone IMAGE:5677082 3' / BM129308 / 312
chemokine (C-C motif) ligand 7 (CCL7) / NM_006273 / 280
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1) / NM_002462 / 257
chemokine (C-X-C motif) ligand 3 (CXCL3) / NM_002090 / 236
chromosome 15 open reading frame 48 (C15orf48) / NM_032413 / 225
matrix metallopeptidase 12 (macrophage elastase) (MMP12) / NM_002426 / 216
leucine rich repeat containing 15 (LRRC15) / NM_130830 / 192
pyrimidinergic receptor P2Y, G-protein coupled, 6 (P2RY6) / NM_176798 / 176
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (CXCL6) / NM_002993 / 167
claudin 14 (CLDN14), transcript variant 1 / NM_144492 / 162
chromosome 9 open reading frame 26 (NF-HEV) (C9orf26) / NM_033439 / 154
serpin peptidase inhibitor, clade B (ovalbumin), member 2 (SERPINB2) / NM_002575 / 153
stanniocalcin 1 (STC1) / NM_003155 / 128
chemokine (C-C motif) ligand 20 (CCL20) / NM_004591 / 125
regulator of G-protein signalling 16 (RGS16) / NM_002928 / 121
interleukin 8 (IL8) / NM_000584 / 121
matrix metallopeptidase 12 (macrophage elastase) (MMP12) / NM_002426 / 106
G protein-coupled receptor 68 (GPR68) / NM_003485 / 98.1
interferon induced transmembrane protein 1 (9-27) (IFITM1) / NM_003641 / 96.0
hect domain and RLD 6 (HERC6), transcript variant 2 / NM_001013002 / 92.2
interleukin 1 receptor-like 1 (IL1RL1), transcript variant 1 / NM_016232 / 88.0
interleukin 11 (IL11) / NM_000641 / 82.5
cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1), nuclear gene encoding mitochondrial protein / NM_000785 / 82.2
chemokine (C-C motif) ligand 8 (CCL8) / NM_005623 / 80.7
neuronal pentraxin I (NPTX1) / NM_002522 / 78.4
SLAM family member 8 (SLAMF8) / NM_020125 / 77.1
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor (ICAM1) / NM_000201 / 75.3
interferon-induced protein 44-like (IFI44L) / NM_006820 / 73.8
CUB domain containing protein 1 (CDCP1), transcript variant 1 / NM_022842 / 72.2
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1) / NM_001511 / 64.7
full-length cDNA clone CS0DH002YJ05 of T cells (Jurkat cell line) of (human) / CR599277 / 61.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2), transcript variant 1 / NM_016817 / 58.8
Fc receptor-like and mucin-like 1 (FCRLM1) / NM_032738 / 58.4
interleukin 1 receptor antagonist (IL1RN), transcript variant 1 / NM_173842 / 56.6
cDNA FLJ26323 fis, clone HRT00813, highly similar to Tissue factor pathway inhibitor 2 precursor (TFPI-2) / AK129833 / 54.1
serpin peptidase inhibitor, clade B (ovalbumin), member 3 (SERPINB3) / NM_006919 / 53.0
solute carrier family 26, member 4 (SLC26A4) / NM_000441 / 52.7
galanin (GAL) / NM_015973 / 49.4
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2) / NM_002203 / 49.2
tissue factor pathway inhibitor 2 (TFPI2) / NM_006528 / 46.1
leukemia inhibitory factor (cholinergic differentiation factor) (LIF) / NM_002309 / 46.0
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2) / NM_002203 / 45.7
interleukin 24 (IL24), transcript variant 1 / NM_006850 / 44.7
chemokine (C-X-C motif) ligand 2 (CXCL2) / NM_002089 / 44.5
MTB (MTB) mRNA, complete cds / AF348994 / 42.6
neuronal pentraxin I (NPTX1) / NM_002522 / 42.3
Fc receptor-like and mucin-like 1 (FCRLM1) / NM_032738 / 41.8
superoxide dismutase 2, mitochondrial, mRNA (cDNA clone MGC:21350 IMAGE:4184203), complete cds / BC016934 / 39.4
myxovirus (influenza virus) resistance 2 (mouse) (MX2) / NM_002463 / 35.9
CD163 molecule (CD163), transcript variant 1 / NM_004244 / 35.5
inhibin, beta A (activin A, activin AB alpha polypeptide) (INHBA) / NM_002192 / 35.1
EST389636 MAGE resequences, MAGO cDNA / AW977527 / 34.7
interleukin 13 receptor, alpha 2 (IL13RA2) / NM_000640 / 34.5
BCL2-related protein A1 (BCL2A1) / NM_004049 / 34.5
chemokine (C-X-C motif) ligand 2 (CXCL2) / NM_002089 / 33.9
protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1 / NM_006504 / 33.8
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3) / NM_000212 / 32.9
myxovirus (influenza virus) resistance 2 (mouse) (MX2) / NM_002463 / 32.4
POU domain, class 2, transcription factor 2 (POU2F2) / NM_002698 / 32.3
chromosome 13 open reading frame 18 (C13orf18) / NM_025113 / 32.1
cDNA: FLJ22487 fis, clone HRC10931 / AK026140 / 31.5
cDNA FLJ11041 fis, clone PLACE1004405 / AK001903 / 31.4
interleukin 6 (interferon, beta 2) (IL6) / NM_000600 / 31.4
CD33 molecule-like 3 (CD33L3) / NM_213602 / 31.3
serum amyloid A2 (SAA2) / NM_030754 / 31.3
bone morphogenetic protein 2 (BMP2) / NM_001200 / 30.5
immediate early response 3 (IER3), transcript variant short / NM_003897 / 30.3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (ITGB3) / NM_000212 / 29.4
thrombomodulin (THBD) / NM_000361 / 29.1
dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (DACT1) / NM_016651 / 28.8
adenosine monophosphate deaminase (isoform E) (AMPD3), transcript variant 1 / NM_000480 / 28.7
regulator of G-protein signalling 16 (RGS16) / NM_002928 / 28.1
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) (GREM1) / NM_013372 / 28.1
tumor necrosis factor, alpha-induced protein 6 (TNFAIP6) / NM_007115 / 28.0
adenosine monophosphate deaminase (isoform E) (AMPD3), transcript variant 1 / NM_000480 / 27.0
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 2 / NM_001002236 / 27.0
dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (DACT1) / NM_016651 / 26.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7 (SERPINB7), transcript variant 1 / NM_003784 / 25.5
colony stimulating factor 2 (granulocyte-macrophage) (CSF2) / NM_000758 / 25.2
Ras-related associated with diabetes (RRAD) / NM_004165 / 25.1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), transcript variant 1 / NM_001712 / 24.7
superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding mitochondrial protein, transcript variant 1 / NM_000636 / 24.2
metallothionein 1X (MT1X) / NM_005952 / 23.0
endothelial cell-specific molecule 1 (ESM1) / NM_007036 / 22.5
transmembrane protein 51 (TMEM51) / NM_018022 / 22.5
serum amyloid A1 (SAA1), transcript variant 1 / NM_000331 / 21.2
metallothionein 1H (MT1H) / NM_005951 / 20.9
chemokine (C-C motif) ligand 2 (CCL2) / NM_002982 / 20.7
lipase, endothelial (LIPG) / NM_006033 / 20.5
metallothionein 1E (functional) (MT1E) / NM_175617 / 19.5
cholesterol 25-hydroxylase (CH25H) / NM_003956 / 19.1
metallothionein 1G (MT1G) / NM_005950 / 19.1
arylsulfatase family, member I, mRNA (cDNA clone IMAGE:5750037) / BC111002 / 18.9
epithelial stromal interaction 1 (breast) (EPSTI1), transcript variant 2 / NM_033255 / 18.9
adenosine A2a receptor (ADORA2A) / NM_000675 / 18.9
metallothionein 1H (MT1H) / NM_005951 / 18.7
metallothionein 1X (MT1X) / NM_005952 / 18.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58) / NM_014314 / 18.2
PR domain containing 1, with ZNF domain (PRDM1), transcript variant 1 / NM_001198 / 18.1
chemokine (C-C motif) ligand 3 (CCL3) / NM_002983 / 18.1
metallothionein 1B (functional) (MT1B) / NM_005947 / 18.1
transmembrane protein 158 (TMEM158) / NM_015444 / 17.7
unknown mRNA / AF495759 / 17.7
ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) / NM_005099 / 17.6
cathepsin S (CTSS) / NM_004079 / 17.5
2'-5'-oligoadenylate synthetase 3, 100kDa (OAS3) / NM_006187 / 17.4
cDNA FLJ37574 fis, clone BRCOC2003100 / AK094893 / 17.1
cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2) / NM_031476 / 17.0
cDNA FLJ13661 fis, clone PLACE1011635, highly similar to heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B (3OST3B1) / AK023723 / 16.9
tripartite motif-containing 63 (TRIM63) / NM_032588 / 16.9
mRNA for AML1a protein, complete cds / D43967 / 16.7
KIAA1199 (KIAA1199) / NM_018689 / 16.7
lipase, endothelial (LIPG) / NM_006033 / 16.7
interleukin 1, beta (IL1B) / NM_000576 / 16.6
interleukin 1 receptor, type II (IL1R2), transcript variant 1 / NM_004633 / 16.6
metallothionein 1G (MT1G) / NM_005950 / 16.6
pp10472 mRNA, complete cds / AF318321 / 16.4
aquaporin 9 (AQP9) / NM_020980 / 16.2
KIAA1199 (KIAA1199) / NM_018689 / 16.2
transmembrane 4 L six family member 1 (TM4SF1) / NM_014220 / 16.1
Ras-related associated with diabetes (RRAD) / NM_004165 / 15.8
H.sapiens mRNA for metallothionein isoform 1R / X97261 / 14.9
sphingosine kinase 1 (SPHK1), transcript variant 1 / NM_021972 / 14.8
leprecan-like 1 (LEPREL1) / NM_018192 / 14.8
hypothetical protein MGC4294, mRNA (cDNA clone MGC:4294 IMAGE:3636069), complete cds / BC002831 / 14.8
ras homolog gene family, member H (RHOH) / NM_004310 / 14.6
wingless-type MMTV integration site family member 2 (WNT2) / NM_003391 / 14.6
metallothionein 1A (functional) (MT1A) / NM_005946 / 14.5
epiregulin (EREG) / NM_001432 / 14.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2) / NM_000963 / 14.5
PDZK1 interacting protein 1 (PDZK1IP1) / NM_005764 / 14.4
tenascin C (hexabrachion) (TNC) / NM_002160 / 14.4
chemokine (C-X-C motif) ligand 3 (CXCL3) / NM_002090 / 14.3
solute carrier family 39 (zinc transporter), member 14 (SLC39A14) / NM_015359 / 14.3
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III (P4HA3) / NM_182904 / 14.2
protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1 / NM_006504 / 14.1
G protein-coupled receptor 84 (GPR84) / NM_020370 / 13.6
cDNA FLJ37310 fis, clone BRAMY2016706 / AK094629 / 13.5
interleukin 32 (IL32), transcript variant 1 / NM_001012631 / 13.4
solute carrier family 16 (monocarboxylic acid transporters), member 6 (SLC16A6) / NM_004694 / 13.3
plasminogen activator, urokinase (PLAU) / NM_002658 / 13.1
XIAP associated factor-1 (BIRC4BP), transcript variant 1 / NM_017523 / 13.1
interferon-induced protein 44 (IFI44) / NM_006417 / 12.8
tryptophan 2,3-dioxygenase (TDO2) / NM_005651 / 12.8
CD743044 UI-H-FT1-bjx-e-03-0-UI.s1 NCI_CGAP_FT1 cDNA clone UI-H-FT1-bjx-e-03-0-UI 3' / CD743044 / 12.7
AI470277 tj18h01.x1 NCI_CGAP_Gas4 cDNA clone IMAGE:2141905 3' / AI470277 / 12.7
interferon induced with helicase C domain 1 (IFIH1) / NM_022168 / 12.6
interleukin 1 family, member 5 (delta) (IL1F5), transcript variant 1 / NM_012275 / 12.6
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2), transcript variant 2 / NM_198951 / 12.5
glycerol kinase (GK), transcript variant 1 / NM_203391 / 12.5
zinc finger CCCH-type containing 12A (ZC3H12A) / NM_025079 / 12.5
XIAP associated factor-1 (BIRC4BP), transcript variant 1 / NM_017523 / 12.5
neuregulin 1 (NRG1), transcript variant HRG-beta2 / NM_013957 / 12.3
neurofilament 3 (150kDa medium) (NEF3) / NM_005382 / 12.3
XIAP associated factor-1 (BIRC4BP), transcript variant 1 / NM_017523 / 12.2
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) / NM_001085 / 12.2
RCSD domain containing 1 (RCSD1) / NM_052862 / 12.1
amphiregulin (schwannoma-derived growth factor) (AREG) / NM_001657 / 12.0
2'-5'-oligoadenylate synthetase 3, 100kDa (OAS3) / NM_006187 / 11.9
TIMP metallopeptidase inhibitor 1 (TIMP1) / NM_003254 / 11.5
protein phosphatase 1, regulatory (inhibitor) subunit 14C (PPP1R14C) / NM_030949 / 11.5
cardiomyopathy associated 1 (CMYA1) / NM_194293 / 11.4
solute carrier family 39 (zinc transporter), member 14 (SLC39A14) / NM_015359 / 11.3
cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2) / NM_031476 / 11.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 (HS3ST3B1) / NM_006041 / 11.1
Rh family, C glycoprotein (RHCG) / NM_016321 / 11.0
leucine-rich repeat LGI family, member 2 (LGI2) / NM_018176 / 10.9
hypothetical protein FLJ14834 (FLJ14834) / NM_032849 / 10.9
potassium channel, subfamily K, member 1 (KCNK1) / NM_002245 / 10.8
endothelin receptor type B (EDNRB), transcript variant 2 / NM_003991 / 10.7
solute carrier family 22 (organic cation transporter), member 4 (SLC22A4) / NM_003059 / 10.7
jun B proto-oncogene (JUNB) / NM_002229 / 10.7
pleckstrin homology-like domain, family A, member 1 (PHLDA1) / NM_007350 / 10.5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) / NM_001085 / 10.4
myosin X (MYO10) / NM_012334 / 10.3
adenosine A2a receptor (ADORA2A) / NM_000675 / 10.2
uridine phosphorylase 1 (UPP1), transcript variant 2 / NM_181597 / 10.2
interferon regulatory factor 7 (IRF7), transcript variant d / NM_004031 / 9.8
CD38 molecule (CD38) / NM_001775 / 9.7
hypothetical protein FLJ14834 (FLJ14834) / NM_032849 / 9.6
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2) / NM_000963 / 9.6
hypothetical LOC387763, mRNA (cDNA clone IMAGE:6272440), partial cds / BC052560 / 9.6
phospholipid scramblase 1 (PLSCR1) / NM_021105 / 9.5
msh homeobox homolog 2 (Drosophila) pseudogene (MSX2P) on chromosome 17 / NR_002307 / 9.3
, clone IMAGE:4179986, mRNA, partial cds / BC008580 / 9.2
LIM and senescent cell antigen-like domains 3 (LIMS3) / NM_033514 / 9.2
neuregulin 1 (NRG1), transcript variant GGF / NM_013961 / 9.2
cDNA clone IMAGE:4822429 / BC047636 / 9.1
glycerol kinase (GK), transcript variant 1 / NM_203391 / 9.1
poly (ADP-ribose) polymerase family, member 14 (PARP14) / NM_017554 / 9.1
myosin X (MYO10) / NM_012334 / 8.9
glutamine-fructose-6-phosphate transaminase 2 (GFPT2) / NM_005110 / 8.9
HUMA1ACM alpha-1-antichymotrypsin {;} , partial (17%) / H25835 / 8.8
transmembrane protein 49, mRNA (cDNA clone IMAGE:4295896), with apparent retained intron / BC024020 / 8.8
neuregulin 1 (NRG1), transcript variant GGF2 / NM_013962 / 8.8
hypothetical protein FLJ36031 (FLJ36031) / NM_175884 / 8.7
nuclear receptor interacting protein 3 (NRIP3) / NM_020645 / 8.6
suppressor of cytokine signaling 3 (SOCS3) / NM_003955 / 8.4
, clone IMAGE:4110919 / BC006384 / 8.4
AF533653 truncated DNA architectural factor HMGA2 {;} , partial (64%) / 8.4
dual specificity phosphatase 5 (DUSP5) / NM_004419 / 8.4
cDNA FLJ37399 fis, clone BRAMY2027587 / AK094718 / 8.3
pleckstrin 2 (PLEK2) / NM_016445 / 8.2
phosphoinositide-3-kinase, catalytic, delta polypeptide (PIK3CD) / NM_005026 / 8.2
LIM and senescent cell antigen-like domains 3, mRNA (cDNA clone IMAGE:30531558), containing frame-shift errors / BC094740 / 8.1
guanylate binding protein 1, interferon-inducible, 67kDa (GBP1) / NM_002053 / 8.1
zinc finger protein 281 (ZNF281) / NM_012482 / 8.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (SERPIND1) / NM_000185 / 8.0